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The map label for this gene is zntR [H]

Identifier: 157960262

GI number: 157960262

Start: 539597

End: 540118

Strand: Direct

Name: zntR [H]

Synonym: Spea_0433

Alternate gene names: 157960262

Gene position: 539597-540118 (Clockwise)

Preceding gene: 157960258

Following gene: 157960263

Centisome position: 10.43

GC content: 45.98

Gene sequence:

>522_bases
ATGTATCGAATTGGTGAGCTTGCACTGCAGTGTGAGGTTAAAGCTGACACTCTAAGGTTTTACGAAAAGCACGGCTTGTT
GTCGCCGTCATCACGCACCGATTCAGGGTATCGCATTTATACCGAAGCGGATGCCGAGCGCTTGCGCTTTATTTTGCGCG
CCAAGGCGGTGGGCTTTACTTTAGCGGAAATCACCGAACTTCTGTCTATCGAACTCGATAAGTCCAATTGGGCTTGCGCC
GATGTAAAAGGCATGGTCGATGATAAATTGGCGAATGTTGAAGCTAAAATCGCCGAGCTAAACCATTTTCAATTATCTCT
GCAGCGCTTGTCGCAAGCTTGCTGTGGCGGCCCTGAAAGTGCGGAGCATTGCTCGATTCTTGAAGCGTTGGAATCGAATA
CTGACAATATCCGCTGTGAAAATGACAAGCATGGTCACGATAAAAAGCTGTTCACTAAAGGCTGCACGACTAAATCAAAT
GCTAAACCGACAAACAAATCGAAAGTTAAATCGAATACTTAA

Upstream 100 bases:

>100_bases
TACTCTCGTTATTACAGTAATAAAACCTGTTGGTTTATTGTTTTATCACTGGCTAATATTTGAGTTTGAAACTGAATATT
TGATTGATTTGGAGCTAGGC

Downstream 100 bases:

>100_bases
AAATACACGTGAGAAGTCGTTATGTTATTAGAAAACTTTATTGAGCTGTTTCTAGAGTCAGCCCCTTGGCTTTTACTAGG
CCTAGTATTAGCAGGCATGT

Product: zinc-responsive transcriptional regulator

Products: NA

Alternate protein names: Zn(II)-responsive regulator of zntA [H]

Number of amino acids: Translated: 173; Mature: 173

Protein sequence:

>173_residues
MYRIGELALQCEVKADTLRFYEKHGLLSPSSRTDSGYRIYTEADAERLRFILRAKAVGFTLAEITELLSIELDKSNWACA
DVKGMVDDKLANVEAKIAELNHFQLSLQRLSQACCGGPESAEHCSILEALESNTDNIRCENDKHGHDKKLFTKGCTTKSN
AKPTNKSKVKSNT

Sequences:

>Translated_173_residues
MYRIGELALQCEVKADTLRFYEKHGLLSPSSRTDSGYRIYTEADAERLRFILRAKAVGFTLAEITELLSIELDKSNWACA
DVKGMVDDKLANVEAKIAELNHFQLSLQRLSQACCGGPESAEHCSILEALESNTDNIRCENDKHGHDKKLFTKGCTTKSN
AKPTNKSKVKSNT
>Mature_173_residues
MYRIGELALQCEVKADTLRFYEKHGLLSPSSRTDSGYRIYTEADAERLRFILRAKAVGFTLAEITELLSIELDKSNWACA
DVKGMVDDKLANVEAKIAELNHFQLSLQRLSQACCGGPESAEHCSILEALESNTDNIRCENDKHGHDKKLFTKGCTTKSN
AKPTNKSKVKSNT

Specific function: Zinc-responsive transcriptional regulator of zntA [H]

COG id: COG0789

COG function: function code K; Predicted transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH merR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789687, Length=138, Percent_Identity=50.7246376811594, Blast_Score=149, Evalue=8e-38,
Organism=Escherichia coli, GI1786695, Length=127, Percent_Identity=34.6456692913386, Blast_Score=74, Evalue=7e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009061
- InterPro:   IPR000551
- InterPro:   IPR015358
- InterPro:   IPR011788 [H]

Pfam domain/function: PF00376 MerR; PF09278 MerR-DNA-bind [H]

EC number: NA

Molecular weight: Translated: 19270; Mature: 19270

Theoretical pI: Translated: 7.39; Mature: 7.39

Prosite motif: PS00552 HTH_MERR_1 ; PS50937 HTH_MERR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
4.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYRIGELALQCEVKADTLRFYEKHGLLSPSSRTDSGYRIYTEADAERLRFILRAKAVGFT
CCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCHH
LAEITELLSIELDKSNWACADVKGMVDDKLANVEAKIAELNHFQLSLQRLSQACCGGPES
HHHHHHHHHEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEHCSILEALESNTDNIRCENDKHGHDKKLFTKGCTTKSNAKPTNKSKVKSNT
HHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MYRIGELALQCEVKADTLRFYEKHGLLSPSSRTDSGYRIYTEADAERLRFILRAKAVGFT
CCCCCCEEEEEECCHHHHHHHHHCCCCCCCCCCCCCEEEEECCCHHHHHHHHHHHHHCHH
LAEITELLSIELDKSNWACADVKGMVDDKLANVEAKIAELNHFQLSLQRLSQACCGGPES
HHHHHHHHHEEECCCCCCCHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
AEHCSILEALESNTDNIRCENDKHGHDKKLFTKGCTTKSNAKPTNKSKVKSNT
HHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]