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The map label for this gene is yhdH [H]

Identifier: 157960181

GI number: 157960181

Start: 401814

End: 403190

Strand: Reverse

Name: yhdH [H]

Synonym: Spea_0352

Alternate gene names: 157960181

Gene position: 403190-401814 (Counterclockwise)

Preceding gene: 157960182

Following gene: 157960180

Centisome position: 7.79

GC content: 48.15

Gene sequence:

>1377_bases
ATGTACAGAAAGAGAGCTCAAATGAGTACAGTAAAAAACGGGCACTTCAGCTCTAGAATTGGCTTTATTATGGCGGCGGC
AGGCTCTGCTGTCGGTGTCGGTAATATCTGGGGCTTCCCCACTCAAGCGGCCACCCACGGCGGCGGCGCATTCTTGCTTG
TTTATCTGTTTCTGATCTTAGTACTCGGCTACCCCATGCTGCTTGCGGAGTTGATGATTGGTCGCCATGGGCAGACTAAC
CCAGCCGATGCCATGGCCAAGGTGGCGACTAAGCCACTTGCGAAGAAGATAGGTAAGGCAATCGGTTTTATCTCTATCAT
TACCGCCACCTTAATCTGTACTTTCTACAGCATTCTATCGGGTTGGTTTGTTAGCTTTGCTATCGCCCCCGTTGCCGAGT
TAACCGGCCAAACCAATGTCGCGTCTTGGTTAATGGACTTCTCGCTATCGCGCAACTTAGTGTTCACCCTTATTTTTATC
GCCATGGTGATACTGGTGATCCGTCAAGGTGTGCAACAAGGTATCGAGCGTTGGTCAAAGCGTTTGATGCCTATGCTGCT
GATCATTTTAGTCGCTGGCGTGGCCTATATCTTGACCCAGCCAGGTGCGATGCAAGGGCTAGAAGTATTATTGGTTCCTG
ATTTTTCACGAGTGTTTGACGCCGATGTTTTGATTGGCGCCTTAGGGCAAACCTTCTTCTCATTAACCATAGGCACCGCA
GCCATGATGGTTTATGGCGCCTACCTGAGCCAGAAAGAAGACTTGAGTAAGCTGACCGCCTACGTCACCTTAACCGATAC
CTGCGTGGCATTTTTAGCCGCACTTATGGTGCTACCTGCCATGTATGTAGCGCAGCATAATGGTGTACAGATTTTTGCCG
AAGATGGCAGCTTATTAAACTCGGATACGCTTGTATTCACCGTTTTGCCAGCGTTATTCGACACCATTGGCGGCATAAGC
CAGTACTTGTTAGCCATCACCTTCTTCATCTTAATGACGATTGCCGGCCTAACATCGGCTATCTCCATCGTTGAGGTACC
TACCAGCTACCTTGTGGAAAAGACCAGCTTGAGTCGTGACAAAGCTACATTAATCGTTGGTAGCGTCGTTGCCGTTCTGT
CTATGGTGGTTGTGTTTAATTTCGAGCTGTTATTTGGCTTTATGATCACCCTAACCACTGAACGGGCTCAACCGCTTATC
GCCCTAGGTATCGCCATCTACTTGGGTTGGATCTGGAACAGAAATCAGCTTATCAGTGCCATTGCCGCACAAGATAACGT
CGACACAAATAGCCTGTTTTGGAAGATATGGCCTTGGTATGTGAAATACGTTTGCCCAGTGCTTATCATCATGATTATTG
TGCAGCTAATTAGCTAA

Upstream 100 bases:

>100_bases
AAACTCAAAATAAAACATCAAAAAACAGATTTTAAGCGCGAGTTTAAGGCGTTGACACATCATTTTAAAGCACTAATATG
CGCGCTCTTAATTGGCAAAG

Downstream 100 bases:

>100_bases
TTCATCACGATTGAACTCACTGTTAAGAAGGGCGATTTTATCGCCCTTTTTTTATACGTAACGCCAGTAAAAAGTGAGAC
TTGTCACACCCACCTGTGAC

Product: sodium:neurotransmitter symporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 458; Mature: 458

Protein sequence:

>458_residues
MYRKRAQMSTVKNGHFSSRIGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLFLILVLGYPMLLAELMIGRHGQTN
PADAMAKVATKPLAKKIGKAIGFISIITATLICTFYSILSGWFVSFAIAPVAELTGQTNVASWLMDFSLSRNLVFTLIFI
AMVILVIRQGVQQGIERWSKRLMPMLLIILVAGVAYILTQPGAMQGLEVLLVPDFSRVFDADVLIGALGQTFFSLTIGTA
AMMVYGAYLSQKEDLSKLTAYVTLTDTCVAFLAALMVLPAMYVAQHNGVQIFAEDGSLLNSDTLVFTVLPALFDTIGGIS
QYLLAITFFILMTIAGLTSAISIVEVPTSYLVEKTSLSRDKATLIVGSVVAVLSMVVVFNFELLFGFMITLTTERAQPLI
ALGIAIYLGWIWNRNQLISAIAAQDNVDTNSLFWKIWPWYVKYVCPVLIIMIIVQLIS

Sequences:

>Translated_458_residues
MYRKRAQMSTVKNGHFSSRIGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLFLILVLGYPMLLAELMIGRHGQTN
PADAMAKVATKPLAKKIGKAIGFISIITATLICTFYSILSGWFVSFAIAPVAELTGQTNVASWLMDFSLSRNLVFTLIFI
AMVILVIRQGVQQGIERWSKRLMPMLLIILVAGVAYILTQPGAMQGLEVLLVPDFSRVFDADVLIGALGQTFFSLTIGTA
AMMVYGAYLSQKEDLSKLTAYVTLTDTCVAFLAALMVLPAMYVAQHNGVQIFAEDGSLLNSDTLVFTVLPALFDTIGGIS
QYLLAITFFILMTIAGLTSAISIVEVPTSYLVEKTSLSRDKATLIVGSVVAVLSMVVVFNFELLFGFMITLTTERAQPLI
ALGIAIYLGWIWNRNQLISAIAAQDNVDTNSLFWKIWPWYVKYVCPVLIIMIIVQLIS
>Mature_458_residues
MYRKRAQMSTVKNGHFSSRIGFIMAAAGSAVGVGNIWGFPTQAATHGGGAFLLVYLFLILVLGYPMLLAELMIGRHGQTN
PADAMAKVATKPLAKKIGKAIGFISIITATLICTFYSILSGWFVSFAIAPVAELTGQTNVASWLMDFSLSRNLVFTLIFI
AMVILVIRQGVQQGIERWSKRLMPMLLIILVAGVAYILTQPGAMQGLEVLLVPDFSRVFDADVLIGALGQTFFSLTIGTA
AMMVYGAYLSQKEDLSKLTAYVTLTDTCVAFLAALMVLPAMYVAQHNGVQIFAEDGSLLNSDTLVFTVLPALFDTIGGIS
QYLLAITFFILMTIAGLTSAISIVEVPTSYLVEKTSLSRDKATLIVGSVVAVLSMVVVFNFELLFGFMITLTTERAQPLI
ALGIAIYLGWIWNRNQLISAIAAQDNVDTNSLFWKIWPWYVKYVCPVLIIMIIVQLIS

Specific function: Putative sodium-dependent transporter [H]

COG id: COG0733

COG function: function code R; Na+-dependent transporters of the SNF family

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family [H]

Homologues:

Organism=Homo sapiens, GI21361581, Length=429, Percent_Identity=25.6410256410256, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI197276623, Length=346, Percent_Identity=25.7225433526012, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI54607094, Length=346, Percent_Identity=25.7225433526012, Blast_Score=96, Evalue=5e-20,
Organism=Homo sapiens, GI4507041, Length=514, Percent_Identity=23.3463035019455, Blast_Score=94, Evalue=4e-19,
Organism=Homo sapiens, GI7657587, Length=394, Percent_Identity=25.8883248730964, Blast_Score=93, Evalue=5e-19,
Organism=Homo sapiens, GI134304856, Length=350, Percent_Identity=26, Blast_Score=93, Evalue=6e-19,
Organism=Homo sapiens, GI171184408, Length=394, Percent_Identity=26.6497461928934, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI171184406, Length=394, Percent_Identity=26.6497461928934, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI171184404, Length=394, Percent_Identity=26.6497461928934, Blast_Score=91, Evalue=2e-18,
Organism=Homo sapiens, GI289191351, Length=407, Percent_Identity=24.0786240786241, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI4557046, Length=407, Percent_Identity=24.0786240786241, Blast_Score=90, Evalue=5e-18,
Organism=Homo sapiens, GI289191377, Length=407, Percent_Identity=24.0786240786241, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI58219014, Length=311, Percent_Identity=24.4372990353698, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI33354281, Length=299, Percent_Identity=24.0802675585284, Blast_Score=80, Evalue=5e-15,
Organism=Homo sapiens, GI51468073, Length=313, Percent_Identity=24.2811501597444, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI21361693, Length=107, Percent_Identity=32.7102803738318, Blast_Score=71, Evalue=2e-12,
Organism=Homo sapiens, GI11181770, Length=298, Percent_Identity=23.1543624161074, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI197276625, Length=156, Percent_Identity=27.5641025641026, Blast_Score=68, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71995588, Length=416, Percent_Identity=24.2788461538462, Blast_Score=95, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17554804, Length=393, Percent_Identity=24.9363867684478, Blast_Score=92, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI25146584, Length=400, Percent_Identity=24, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17542050, Length=110, Percent_Identity=31.8181818181818, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17535731, Length=116, Percent_Identity=29.3103448275862, Blast_Score=68, Evalue=1e-11,
Organism=Drosophila melanogaster, GI17136952, Length=392, Percent_Identity=24.7448979591837, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI281364394, Length=392, Percent_Identity=24.7448979591837, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574704, Length=392, Percent_Identity=24.7448979591837, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17136950, Length=392, Percent_Identity=24.7448979591837, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI28574702, Length=392, Percent_Identity=24.7448979591837, Blast_Score=96, Evalue=3e-20,
Organism=Drosophila melanogaster, GI281365034, Length=468, Percent_Identity=23.7179487179487, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24652942, Length=506, Percent_Identity=22.5296442687747, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI24661428, Length=493, Percent_Identity=23.3265720081136, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI45551088, Length=506, Percent_Identity=22.1343873517787, Blast_Score=87, Evalue=3e-17,
Organism=Drosophila melanogaster, GI19921352, Length=470, Percent_Identity=22.5531914893617, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24584353, Length=470, Percent_Identity=22.5531914893617, Blast_Score=85, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24654186, Length=286, Percent_Identity=25.8741258741259, Blast_Score=72, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24639516, Length=297, Percent_Identity=24.9158249158249, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24639514, Length=297, Percent_Identity=24.9158249158249, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI221329674, Length=297, Percent_Identity=24.9158249158249, Blast_Score=67, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000175 [H]

Pfam domain/function: PF00209 SNF [H]

EC number: NA

Molecular weight: Translated: 49839; Mature: 49839

Theoretical pI: Translated: 8.69; Mature: 8.69

Prosite motif: PS50267 NA_NEUROTRAN_SYMP_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure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HHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]