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The map label for this gene is aer [H]

Identifier: 157960166

GI number: 157960166

Start: 380368

End: 381921

Strand: Direct

Name: aer [H]

Synonym: Spea_0337

Alternate gene names: 157960166

Gene position: 380368-381921 (Clockwise)

Preceding gene: 157960165

Following gene: 157960170

Centisome position: 7.35

GC content: 46.72

Gene sequence:

>1554_bases
ATGGACGAAGAGTACCAGTATCCCGCCAATTACAATTTAATCTCAATCACGTCTCCTTCTAGTCATATTAAATATGCCAG
TCCTCACTTTTCTGAAGTGGCGGGATTTGCAGATGGCGAGCTTATTGGTCTTCCCCATAATGTTGTCAGACATCCGGATA
TGCCCAAAGCCGCGTTTAAAGATCTGTGGGGTCACTTGCAGAGTGGCAACCATTGGATGGGAATGGTGAAAAACAGTCGT
AAGGGGGGAGGTTATTATTGGGTCGATGCATTCGCCTCGCCGATAAAAAACAATGGAGAGATTGTCGAACTGCAATCGGT
TCGCTTTAAACCGGAACGGATCCATGTTAAACGAGCCGAGGCCGCTTATAAGCAATTATCAAATGATAAAAAGCCTTTTC
AATTGAGCATAGGCTTGAGAACTCGCTTGTGGCAGCGCAGCGCCTTTTGTTATGGCATCGCCGCGCTTATCTCCTATGGT
ATCGCCACCTTTACCCAAAATACCGCTCTGACGCTGGCATCCTTTTTCGTTATGGCGACTCTAATTAGTTATCTGTTAAC
TCGCCCCTTGGAGCGACTGGCAAAAGAGGCTCGTAAAGACTTTAATAATCCGCTAATGGAACTCATCTATACGGGGAAGG
TCAATGACTTTTCTGAAATTGAGTTGGCGATGAAGATGCGTCGACAGCACGTAAAAGCATTGATTGGGCGGGTAAATATC
TCTGTGATGGAGGCCTGTGACAAGACCTTAGATAACGCCAAGCTAGCCACCCAGAACAACCATAAAGTCACCGAACATCT
CAATACTCAGAAAACAGAGATTGAAATGGTGGCAACGGCGGTGAATGAGATGCAGGCGGCATCGACCGAGATCTCACAAA
ATGCTCAGGGCACCGCTGAAGCGACAATGCAGACGCAAAGTACCATGTCGGAGAATTTGGAGTGCATTAATCAGGTTAAT
AAGTCGATGTTGGAGCTCGTCGATGAGTTAGCCTCAATATCCAGTACCGTGGTATCGCTCGATAAGCAAACCCAGCAAAT
TAGTTCGGTGATCGATGTGATTAATGGCATTGCCGAGCAGACCAACCTACTAGCGCTAAATGCTGCGATTGAAGCGGCTC
GAGCCGGAGACTCTGGCCGTGGCTTTGCAGTGGTGTCCGATGAGGTGCGCACTTTAGCGCAGCGTACTCAGGTTGCAACC
ACAGAGATCCAGACGGCGATTGAGCAGATCCAGACCAATAGCCAAGTTGCGGTTAAATCGCTTGAAATTGGTAATGACAA
ATCCAGCAAGACGGTCAATATCATCAATGCCTCACTGAGCAAAATCAATGAACTTGAGGAATTGATTGAGGGCATAGTGG
AGCGTAATCAGCAGATAGCCGTGGCCATCGAAGAGCAGGTCTATGTCTGTAATGAGGTCAACACCAATGTGCAGATGGTT
AATTGTAAGGTGTCAGAGTCTTATGATCTGATTACCGTAACCAATACGCTCAACCAAGAGGTTGAGAACAGTACCGACGA
TCTATCCAATACCATCAGAAATTTCAATATGTAG

Upstream 100 bases:

>100_bases
TAGATGAAATAAATTACGCAGATGACTTTGATGGAAAGCGAATATTGGTACTACACTGAACGGTAGTTTTGTTTTATGCC
ATTAAATAAAGGATTATGTT

Downstream 100 bases:

>100_bases
TGGGATTAGTTTAAATAGAAAGGGTCTAGCCGAGTACTAGGCCCTTTTTAGTTTTTGGGGAAACATGGTAAGGCTGCTTA
TACTGATTGCTAGTACTATT

Product: Pas/Pac sensor containing methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 517; Mature: 517

Protein sequence:

>517_residues
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELIGLPHNVVRHPDMPKAAFKDLWGHLQSGNHWMGMVKNSR
KGGGYYWVDAFASPIKNNGEIVELQSVRFKPERIHVKRAEAAYKQLSNDKKPFQLSIGLRTRLWQRSAFCYGIAALISYG
IATFTQNTALTLASFFVMATLISYLLTRPLERLAKEARKDFNNPLMELIYTGKVNDFSEIELAMKMRRQHVKALIGRVNI
SVMEACDKTLDNAKLATQNNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAEATMQTQSTMSENLECINQVN
KSMLELVDELASISSTVVSLDKQTQQISSVIDVINGIAEQTNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVAT
TEIQTAIEQIQTNSQVAVKSLEIGNDKSSKTVNIINASLSKINELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
NCKVSESYDLITVTNTLNQEVENSTDDLSNTIRNFNM

Sequences:

>Translated_517_residues
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELIGLPHNVVRHPDMPKAAFKDLWGHLQSGNHWMGMVKNSR
KGGGYYWVDAFASPIKNNGEIVELQSVRFKPERIHVKRAEAAYKQLSNDKKPFQLSIGLRTRLWQRSAFCYGIAALISYG
IATFTQNTALTLASFFVMATLISYLLTRPLERLAKEARKDFNNPLMELIYTGKVNDFSEIELAMKMRRQHVKALIGRVNI
SVMEACDKTLDNAKLATQNNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAEATMQTQSTMSENLECINQVN
KSMLELVDELASISSTVVSLDKQTQQISSVIDVINGIAEQTNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVAT
TEIQTAIEQIQTNSQVAVKSLEIGNDKSSKTVNIINASLSKINELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
NCKVSESYDLITVTNTLNQEVENSTDDLSNTIRNFNM
>Mature_517_residues
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELIGLPHNVVRHPDMPKAAFKDLWGHLQSGNHWMGMVKNSR
KGGGYYWVDAFASPIKNNGEIVELQSVRFKPERIHVKRAEAAYKQLSNDKKPFQLSIGLRTRLWQRSAFCYGIAALISYG
IATFTQNTALTLASFFVMATLISYLLTRPLERLAKEARKDFNNPLMELIYTGKVNDFSEIELAMKMRRQHVKALIGRVNI
SVMEACDKTLDNAKLATQNNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAEATMQTQSTMSENLECINQVN
KSMLELVDELASISSTVVSLDKQTQQISSVIDVINGIAEQTNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVAT
TEIQTAIEQIQTNSQVAVKSLEIGNDKSSKTVNIINASLSKINELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
NCKVSESYDLITVTNTLNQEVENSTDDLSNTIRNFNM

Specific function: Signal transducer for aerotaxis. The aerotactic response is the accumulation of cells around air bubbles. The nature of the sensory stimulus detected by this protein is the proton motive force or cellular redox state. It uses a FAD prosthetic group as a r

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=519, Percent_Identity=28.3236994219653, Blast_Score=183, Evalue=2e-47,
Organism=Escherichia coli, GI2367378, Length=239, Percent_Identity=30.9623430962343, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787690, Length=362, Percent_Identity=23.7569060773481, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788194, Length=189, Percent_Identity=33.8624338624339, Blast_Score=91, Evalue=2e-19,
Organism=Escherichia coli, GI1788195, Length=238, Percent_Identity=29.8319327731092, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013655 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal; PF08447 PAS_3 [H]

EC number: NA

Molecular weight: Translated: 57398; Mature: 57398

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELIGLPHNVVRHPDMPKAAFK
CCCCCCCCCCCCEEEECCCCCCCEECCCCHHHHCCCCCCCEECCCHHHHCCCCCCHHHHH
DLWGHLQSGNHWMGMVKNSRKGGGYYWVDAFASPIKNNGEIVELQSVRFKPERIHVKRAE
HHHHHHCCCCCEEEEECCCCCCCCEEEHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHH
AAYKQLSNDKKPFQLSIGLRTRLWQRSAFCYGIAALISYGIATFTQNTALTLASFFVMAT
HHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LISYLLTRPLERLAKEARKDFNNPLMELIYTGKVNDFSEIELAMKMRRQHVKALIGRVNI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
SVMEACDKTLDNAKLATQNNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAE
HHHHHHHHHHCCCEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ATMQTQSTMSENLECINQVNKSMLELVDELASISSTVVSLDKQTQQISSVIDVINGIAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVATTEIQTAIEQIQTNSQVAVKS
HHEEEHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEE
LEIGNDKSSKTVNIINASLSKINELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
EECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCCCEEEE
NCKVSESYDLITVTNTLNQEVENSTDDLSNTIRNFNM
EEEECCCCCEEEEECHHHHHHHCCHHHHHHHHHHCCC
>Mature Secondary Structure
MDEEYQYPANYNLISITSPSSHIKYASPHFSEVAGFADGELIGLPHNVVRHPDMPKAAFK
CCCCCCCCCCCCEEEECCCCCCCEECCCCHHHHCCCCCCCEECCCHHHHCCCCCCHHHHH
DLWGHLQSGNHWMGMVKNSRKGGGYYWVDAFASPIKNNGEIVELQSVRFKPERIHVKRAE
HHHHHHCCCCCEEEEECCCCCCCCEEEHHHHHCCCCCCCCEEEEECCCCCHHHHHHHHHH
AAYKQLSNDKKPFQLSIGLRTRLWQRSAFCYGIAALISYGIATFTQNTALTLASFFVMAT
HHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
LISYLLTRPLERLAKEARKDFNNPLMELIYTGKVNDFSEIELAMKMRRQHVKALIGRVNI
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCH
SVMEACDKTLDNAKLATQNNHKVTEHLNTQKTEIEMVATAVNEMQAASTEISQNAQGTAE
HHHHHHHHHHCCCEECCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
ATMQTQSTMSENLECINQVNKSMLELVDELASISSTVVSLDKQTQQISSVIDVINGIAEQ
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TNLLALNAAIEAARAGDSGRGFAVVSDEVRTLAQRTQVATTEIQTAIEQIQTNSQVAVKS
HHEEEHHHHHHHHHCCCCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHEEEE
LEIGNDKSSKTVNIINASLSKINELEELIEGIVERNQQIAVAIEEQVYVCNEVNTNVQMV
EECCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCCCEEEE
NCKVSESYDLITVTNTLNQEVENSTDDLSNTIRNFNM
EEEECCCCCEEEEECHHHHHHHCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 9190831; 9380671 [H]