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The map label for this gene is ndh [H]

Identifier: 157960093

GI number: 157960093

Start: 296091

End: 297299

Strand: Reverse

Name: ndh [H]

Synonym: Spea_0264

Alternate gene names: 157960093

Gene position: 297299-296091 (Counterclockwise)

Preceding gene: 157960095

Following gene: 157960087

Centisome position: 5.75

GC content: 46.82

Gene sequence:

>1209_bases
ATGTCTCGTATTGTTATTGTTGGTGGTGGCGCTGCAGGTCTTGAAATCGCAAGCATGCTAGGTCGCAGTGTAAATAGCCA
AGATGAAGTTATTCTGGTTGAAGGTGAAACTCACCATTATTGGAAGCCACGCTTTCATGAGATTGCTGCAGGTACTTTTG
ACAGCGATCTCGACACAATCTGCTATTTCAGCCATGGCGCTAATAATGGTTACATGCATTACCAAGCTTGGATGACAGAC
GTCAATCGAGCGGCCAAGCAACTCGTGGTTCGTAAGCCTAACGGTGAAACTGATACGCTAGCTTACGATTACTTAATCAT
TGCCATCGGCGCAATTAGTAATGACTTTGCTACCCAAGGTGCGAAAGAGCATTGCCTATTCTTAGATACACCAGAGCAAG
CCCGTGATAGCTGGCACCAAATCAGCTCACTGCTGCGCTCAGGTCTGAGTCGCACCATTAATATCGTTGGCGCTGGTGCC
ACCGGTTTAGAGCTCGCGGCTGAATTAGCTAAAGTCAGTGAAGAGTTAAGTCGCAATCCTTATGCGGCAAAGCTTAATAT
CAACTTGATTGAAGCTGCAGACCGTGTATTACCAAACGGCCCAGTGAAAATGTCTGAGCAAGCATTATTAAGGCTTGAGA
AGTATCAAGTTAATGTCATGCTCAATACCCGTATCGCCAGTGTTGAAGCGGATCGTATGACCACCAGCGACGGCCAAGTG
CTAAATGCCGACGTGCAATTTTGGGCTGCAGGTATTAAGGCGCCGGATTGGCTAAAAGAGATTGGCGGTCTGCAGAGCAA
TTCGCTAAATCAATTAGTGGTTGAGCAAACTCTGGCAACGACATTTGATTCATCGATTTTCGCTCTGGGTGATTGCGCCG
CGATCCCACAAGCAGATGGCAGCCAGGTACCGCCAAAAGCACAAGCAGCTAACCGTGCAGCCGTGCATTTAGCTAAAAAT
CTTGTTGCCCATTTAAAGGGCAAGCCCCTCAAGCCTTTCGTCTACAACGACGGTGGCATGGTAGTCGCTATCGGCCATAA
CTTTGCCATTAGCACCATGATGAACGATAGATTGATCTTAAAAGGCCGCCTAGTCCGTCGCCTCTACGATACGATTTTCC
GTTTACATCAAAAAACTGTCAGTGGTTACTTAGCCATGTCACGTTTGATTATCTTCAAGCGACTAAAGTGTCTATTTAAA
CCAGTCTAA

Upstream 100 bases:

>100_bases
CCATTAAAGCCCTGCACTCGGTCATACCCTGCGTATCCCTTTCAGTCCCAAGGCTCTTGTTAAATTACATCCGCATCTGT
CGATGCTTAGAGGAATTATT

Downstream 100 bases:

>100_bases
TTGCTAAGTCACACACAACTAAATGTATGATTCGCCTCTTTGATTGCCTCCCCCTAAGGTTATTAGGGGTAAGGCGGACC
ACCTAATTAAGCCCGCTTAT

Product: FAD-dependent pyridine nucleotide-disulfide oxidoreductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSRIVIVGGGAAGLEIASMLGRSVNSQDEVILVEGETHHYWKPRFHEIAAGTFDSDLDTICYFSHGANNGYMHYQAWMTD
VNRAAKQLVVRKPNGETDTLAYDYLIIAIGAISNDFATQGAKEHCLFLDTPEQARDSWHQISSLLRSGLSRTINIVGAGA
TGLELAAELAKVSEELSRNPYAAKLNINLIEAADRVLPNGPVKMSEQALLRLEKYQVNVMLNTRIASVEADRMTTSDGQV
LNADVQFWAAGIKAPDWLKEIGGLQSNSLNQLVVEQTLATTFDSSIFALGDCAAIPQADGSQVPPKAQAANRAAVHLAKN
LVAHLKGKPLKPFVYNDGGMVVAIGHNFAISTMMNDRLILKGRLVRRLYDTIFRLHQKTVSGYLAMSRLIIFKRLKCLFK
PV

Sequences:

>Translated_402_residues
MSRIVIVGGGAAGLEIASMLGRSVNSQDEVILVEGETHHYWKPRFHEIAAGTFDSDLDTICYFSHGANNGYMHYQAWMTD
VNRAAKQLVVRKPNGETDTLAYDYLIIAIGAISNDFATQGAKEHCLFLDTPEQARDSWHQISSLLRSGLSRTINIVGAGA
TGLELAAELAKVSEELSRNPYAAKLNINLIEAADRVLPNGPVKMSEQALLRLEKYQVNVMLNTRIASVEADRMTTSDGQV
LNADVQFWAAGIKAPDWLKEIGGLQSNSLNQLVVEQTLATTFDSSIFALGDCAAIPQADGSQVPPKAQAANRAAVHLAKN
LVAHLKGKPLKPFVYNDGGMVVAIGHNFAISTMMNDRLILKGRLVRRLYDTIFRLHQKTVSGYLAMSRLIIFKRLKCLFK
PV
>Mature_401_residues
SRIVIVGGGAAGLEIASMLGRSVNSQDEVILVEGETHHYWKPRFHEIAAGTFDSDLDTICYFSHGANNGYMHYQAWMTDV
NRAAKQLVVRKPNGETDTLAYDYLIIAIGAISNDFATQGAKEHCLFLDTPEQARDSWHQISSLLRSGLSRTINIVGAGAT
GLELAAELAKVSEELSRNPYAAKLNINLIEAADRVLPNGPVKMSEQALLRLEKYQVNVMLNTRIASVEADRMTTSDGQVL
NADVQFWAAGIKAPDWLKEIGGLQSNSLNQLVVEQTLATTFDSSIFALGDCAAIPQADGSQVPPKAQAANRAAVHLAKNL
VAHLKGKPLKPFVYNDGGMVVAIGHNFAISTMMNDRLILKGRLVRRLYDTIFRLHQKTVSGYLAMSRLIIFKRLKCLFKP
V

Specific function: Transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Does not couple the redox reaction to proton translocation [H]

COG id: COG1252

COG function: function code C; NADH dehydrogenase, FAD-containing subunit

Gene ontology:

Cell location: Cell membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH dehydrogenase family [H]

Homologues:

Organism=Escherichia coli, GI1787352, Length=426, Percent_Identity=38.7323943661972, Blast_Score=299, Evalue=3e-82,
Organism=Escherichia coli, GI1789065, Length=339, Percent_Identity=27.4336283185841, Blast_Score=75, Evalue=6e-15,
Organism=Escherichia coli, GI1788892, Length=231, Percent_Identity=29.4372294372294, Blast_Score=62, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6323515, Length=462, Percent_Identity=25.7575757575758, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6323794, Length=410, Percent_Identity=25.3658536585366, Blast_Score=68, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6320118, Length=360, Percent_Identity=25.2777777777778, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013027
- InterPro:   IPR001327 [H]

Pfam domain/function: PF00070 Pyr_redox; PF07992 Pyr_redox_2 [H]

EC number: =1.6.99.3 [H]

Molecular weight: Translated: 44049; Mature: 43918

Theoretical pI: Translated: 8.31; Mature: 8.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRIVIVGGGAAGLEIASMLGRSVNSQDEVILVEGETHHYWKPRFHEIAAGTFDSDLDTI
CCEEEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCEE
CYFSHGANNGYMHYQAWMTDVNRAAKQLVVRKPNGETDTLAYDYLIIAIGAISNDFATQG
EEEECCCCCCEEEHHHHHHHHHHHHHHHEEECCCCCCCHHHHHEEEEEEECCCCHHHCCC
AKEHCLFLDTPEQARDSWHQISSLLRSGLSRTINIVGAGATGLELAAELAKVSEELSRNP
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHCCC
YAAKLNINLIEAADRVLPNGPVKMSEQALLRLEKYQVNVMLNTRIASVEADRMTTSDGQV
CEEEEEEEEEHHHHHHCCCCCCCCCHHHHHHEEEEEEEEEEEEEEEEEECCCEECCCCCE
LNADVQFWAAGIKAPDWLKEIGGLQSNSLNQLVVEQTLATTFDSSIFALGDCAAIPQADG
EECCHHEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
SQVPPKAQAANRAAVHLAKNLVAHLKGKPLKPFVYNDGGMVVAIGHNFAISTMMNDRLIL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCEEEEECCCCEEEH
KGRLVRRLYDTIFRLHQKTVSGYLAMSRLIIFKRLKCLFKPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
SRIVIVGGGAAGLEIASMLGRSVNSQDEVILVEGETHHYWKPRFHEIAAGTFDSDLDTI
CEEEEEECCHHHHHHHHHHCCCCCCCCCEEEEECCCCCCCCCCHHHHHCCCCCCCCCEE
CYFSHGANNGYMHYQAWMTDVNRAAKQLVVRKPNGETDTLAYDYLIIAIGAISNDFATQG
EEEECCCCCCEEEHHHHHHHHHHHHHHHEEECCCCCCCHHHHHEEEEEEECCCCHHHCCC
AKEHCLFLDTPEQARDSWHQISSLLRSGLSRTINIVGAGATGLELAAELAKVSEELSRNP
CCCCEEEECCCHHHHHHHHHHHHHHHHHHHHEEEEEECCCHHHHHHHHHHHHHHHHHCCC
YAAKLNINLIEAADRVLPNGPVKMSEQALLRLEKYQVNVMLNTRIASVEADRMTTSDGQV
CEEEEEEEEEHHHHHHCCCCCCCCCHHHHHHEEEEEEEEEEEEEEEEEECCCEECCCCCE
LNADVQFWAAGIKAPDWLKEIGGLQSNSLNQLVVEQTLATTFDSSIFALGDCAAIPQADG
EECCHHEEECCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCC
SQVPPKAQAANRAAVHLAKNLVAHLKGKPLKPFVYNDGGMVVAIGHNFAISTMMNDRLIL
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCEEEEECCCEEEEECCCCEEEH
KGRLVRRLYDTIFRLHQKTVSGYLAMSRLIIFKRLKCLFKPV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 6265208; 8905232; 9278503 [H]