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The map label for this gene is katE [C]

Identifier: 157959955

GI number: 157959955

Start: 136765

End: 138279

Strand: Direct

Name: katE [C]

Synonym: Spea_0125

Alternate gene names: 157959955

Gene position: 136765-138279 (Clockwise)

Preceding gene: 157959953

Following gene: 157959956

Centisome position: 2.64

GC content: 43.56

Gene sequence:

>1515_bases
ATGGAAATTGTAAAAAAGGCTGGTTTGGCCCTATCGTTGAGCTTGGTTGTTGTGAATGTGCAGGCTGAAACGTTAACACG
TGACAATGGTGCCCCAGTAGGAGACAACCAAAACTCAATCACTGCGGGGAGTAACGGCAGTGTGCTGCTACAAGATGTCC
AGTTGATCCAGAAGTTACAGAGATTTGCGCGTGAGCGGATCCCTGAGCGCGTAGTTCACGCTAGAGGAACTGGTGTACAT
GGGGAGTTTATTGCTAGTAGTGATTTGAGTGAGTTAACACAGGCCGCACCGTTTGCTGAAAAAGGCAAAATTACTCCGGT
ATTCGTACGCTTTTCAACAGTTATTCATTCAAAAGGTTCGCCAGAAACTCTACGGGACCCTAGAGGTTTTGCGACTCGTT
TTTACTCAGATCAAGGTAACTGGGATCTTGTGGGGAACAACTTGCCGGTGTTCTTTATCCGTGATGCGATAAAGTTTCCA
GATATGGTGCACTCACTTAAGCCGTCGCCTATTACTAATCTACAGGACCCAAATCGCTTTTTTGATTTTTTCAGTCATGA
AGCTACAGCAACAAATATGCTGACTTGGGTTTATACCAACTTAGGTACTCCTGCTAGCTACCGAAAAATGGACGGTTGGG
GAGTGCATGCATATAAATTTATTAACGATGAGCATCAGGTTAAATACGTAAAGTTTCATTGGAAAAGCCAACAAGGTGTA
GAAGGGCTAAGGCCTGATGAAGTCGTTAAAACTCAAGGCCAGAATTTTAACCATCTAACAGACGACCTTTATAGCGAGAT
TAACAAGGGCAACTTCCCAAAATGGGATCTTATGGTCAAGGTATTGCGCCCAGAGGATTTGAACAAGTTTGATTACAACC
CACTTGATGCAACAAAAATGTGGCTGGATGTACCAGAAACTAAAGTGGGCACTATGACGCTCAATCGCGTCCCGGATAAC
TTCTTTCAGGAAACAGAACAGGCAGCTTTTGCGCCTTCAAACTTAATACCCGGTATTGAACCTTCGGAAGATAAGTTGCT
TCAGGGACGTATTTTTTCCTATGCCGATACTCAGCTTTATCGTTTAGGTGCCAACTTGTCTCAATTGCCAATTAACCAAC
CTAAGATGGCTGTGGCAAATCATAATCAAGAAGGGGCAGCTAATTATGGTCGTACAAGCTCTGATGTGAATTATCAACCT
AGCACTAAGCTCGCATTAGCTGAAGATCATCGTTATCGAGCCGTACAAACACCCCTATCGGGCACAGTTCTGCAAGCGGT
TATTGCTAAACAAGATAATTTCACTCAGGCGGGCGTGCTTTACCGTAGTTTGAGTAAACAAGATAAGCGCGATCTTATTA
CCAATTTATCTGCTGACTTAGGCAAGGTGACAGACAGTCATGTTAAGCATCAAATGTTGAGTTATTTCTATCAGGCGGAT
AAGGACTTTGGTAAGCGTTTAACGCAAGCTGTGGCGGGTGATTTAAATGAAGTGAAAAAACTCGCCAATATGTAG

Upstream 100 bases:

>100_bases
CGATACAACCAATCGATAAAGGTTGCTTCTTTTAATCGACATTATCGCTCAAACTGTTTTTGGGCAGAAAGAGCGTGCGT
TGTTAATTAAGAGAATACTC

Downstream 100 bases:

>100_bases
CTAGTAACTAACTCTATAGGTTAACGCTTAATGGGCCGGCGTTAACAGTTCCCGAGTCAGTCTCTTGATTCGGTTTCTCG
AGTAAGTCCCGTAAGGCGTG

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MEIVKKAGLALSLSLVVVNVQAETLTRDNGAPVGDNQNSITAGSNGSVLLQDVQLIQKLQRFARERIPERVVHARGTGVH
GEFIASSDLSELTQAAPFAEKGKITPVFVRFSTVIHSKGSPETLRDPRGFATRFYSDQGNWDLVGNNLPVFFIRDAIKFP
DMVHSLKPSPITNLQDPNRFFDFFSHEATATNMLTWVYTNLGTPASYRKMDGWGVHAYKFINDEHQVKYVKFHWKSQQGV
EGLRPDEVVKTQGQNFNHLTDDLYSEINKGNFPKWDLMVKVLRPEDLNKFDYNPLDATKMWLDVPETKVGTMTLNRVPDN
FFQETEQAAFAPSNLIPGIEPSEDKLLQGRIFSYADTQLYRLGANLSQLPINQPKMAVANHNQEGAANYGRTSSDVNYQP
STKLALAEDHRYRAVQTPLSGTVLQAVIAKQDNFTQAGVLYRSLSKQDKRDLITNLSADLGKVTDSHVKHQMLSYFYQAD
KDFGKRLTQAVAGDLNEVKKLANM

Sequences:

>Translated_504_residues
MEIVKKAGLALSLSLVVVNVQAETLTRDNGAPVGDNQNSITAGSNGSVLLQDVQLIQKLQRFARERIPERVVHARGTGVH
GEFIASSDLSELTQAAPFAEKGKITPVFVRFSTVIHSKGSPETLRDPRGFATRFYSDQGNWDLVGNNLPVFFIRDAIKFP
DMVHSLKPSPITNLQDPNRFFDFFSHEATATNMLTWVYTNLGTPASYRKMDGWGVHAYKFINDEHQVKYVKFHWKSQQGV
EGLRPDEVVKTQGQNFNHLTDDLYSEINKGNFPKWDLMVKVLRPEDLNKFDYNPLDATKMWLDVPETKVGTMTLNRVPDN
FFQETEQAAFAPSNLIPGIEPSEDKLLQGRIFSYADTQLYRLGANLSQLPINQPKMAVANHNQEGAANYGRTSSDVNYQP
STKLALAEDHRYRAVQTPLSGTVLQAVIAKQDNFTQAGVLYRSLSKQDKRDLITNLSADLGKVTDSHVKHQMLSYFYQAD
KDFGKRLTQAVAGDLNEVKKLANM
>Mature_504_residues
MEIVKKAGLALSLSLVVVNVQAETLTRDNGAPVGDNQNSITAGSNGSVLLQDVQLIQKLQRFARERIPERVVHARGTGVH
GEFIASSDLSELTQAAPFAEKGKITPVFVRFSTVIHSKGSPETLRDPRGFATRFYSDQGNWDLVGNNLPVFFIRDAIKFP
DMVHSLKPSPITNLQDPNRFFDFFSHEATATNMLTWVYTNLGTPASYRKMDGWGVHAYKFINDEHQVKYVKFHWKSQQGV
EGLRPDEVVKTQGQNFNHLTDDLYSEINKGNFPKWDLMVKVLRPEDLNKFDYNPLDATKMWLDVPETKVGTMTLNRVPDN
FFQETEQAAFAPSNLIPGIEPSEDKLLQGRIFSYADTQLYRLGANLSQLPINQPKMAVANHNQEGAANYGRTSSDVNYQP
STKLALAEDHRYRAVQTPLSGTVLQAVIAKQDNFTQAGVLYRSLSKQDKRDLITNLSADLGKVTDSHVKHQMLSYFYQAD
KDFGKRLTQAVAGDLNEVKKLANM

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=484, Percent_Identity=38.8429752066116, Blast_Score=355, Evalue=4e-98,
Organism=Escherichia coli, GI48994891, Length=500, Percent_Identity=38.4, Blast_Score=344, Evalue=9e-96,
Organism=Caenorhabditis elegans, GI25151141, Length=480, Percent_Identity=40.625, Blast_Score=384, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI25147792, Length=478, Percent_Identity=40.5857740585774, Blast_Score=383, Evalue=1e-106,
Organism=Caenorhabditis elegans, GI71998444, Length=475, Percent_Identity=40, Blast_Score=379, Evalue=1e-105,
Organism=Saccharomyces cerevisiae, GI6320462, Length=486, Percent_Identity=36.6255144032922, Blast_Score=300, Evalue=3e-82,
Organism=Saccharomyces cerevisiae, GI6321525, Length=532, Percent_Identity=34.0225563909774, Blast_Score=298, Evalue=1e-81,
Organism=Drosophila melanogaster, GI17981717, Length=480, Percent_Identity=40, Blast_Score=364, Evalue=1e-101,
Organism=Drosophila melanogaster, GI19920968, Length=480, Percent_Identity=38.125, Blast_Score=351, Evalue=6e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 56556; Mature: 56556

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIVKKAGLALSLSLVVVNVQAETLTRDNGAPVGDNQNSITAGSNGSVLLQDVQLIQKLQ
CCCHHHCCCEEEEEEEEEEEEHHHEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHH
RFARERIPERVVHARGTGVHGEFIASSDLSELTQAAPFAEKGKITPVFVRFSTVIHSKGS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCHHCCCCCEEEEEEEHHHHCCCC
PETLRDPRGFATRFYSDQGNWDLVGNNLPVFFIRDAIKFPDMVHSLKPSPITNLQDPNRF
CCHHCCCCCHHHHEECCCCCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHH
FDFFSHEATATNMLTWVYTNLGTPASYRKMDGWGVHAYKFINDEHQVKYVKFHWKSQQGV
HHHHHCCHHHHHHHEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCC
EGLRPDEVVKTQGQNFNHLTDDLYSEINKGNFPKWDLMVKVLRPEDLNKFDYNPLDATKM
CCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHEEEEECCCCCCCCCCCCCCHHHH
WLDVPETKVGTMTLNRVPDNFFQETEQAAFAPSNLIPGIEPSEDKLLQGRIFSYADTQLY
EEECCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHH
RLGANLSQLPINQPKMAVANHNQEGAANYGRTSSDVNYQPSTKLALAEDHRYRAVQTPLS
HHCCCHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCC
GTVLQAVIAKQDNFTQAGVLYRSLSKQDKRDLITNLSADLGKVTDSHVKHQMLSYFYQAD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDFGKRLTQAVAGDLNEVKKLANM
HHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure
MEIVKKAGLALSLSLVVVNVQAETLTRDNGAPVGDNQNSITAGSNGSVLLQDVQLIQKLQ
CCCHHHCCCEEEEEEEEEEEEHHHEECCCCCCCCCCCCCEECCCCCCCHHHHHHHHHHHH
RFARERIPERVVHARGTGVHGEFIASSDLSELTQAAPFAEKGKITPVFVRFSTVIHSKGS
HHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHCCCHHCCCCCEEEEEEEHHHHCCCC
PETLRDPRGFATRFYSDQGNWDLVGNNLPVFFIRDAIKFPDMVHSLKPSPITNLQDPNRF
CCHHCCCCCHHHHEECCCCCEEEECCCCCEEEEHHHHHHHHHHHHCCCCCCCCCCCHHHH
FDFFSHEATATNMLTWVYTNLGTPASYRKMDGWGVHAYKFINDEHQVKYVKFHWKSQQGV
HHHHHCCHHHHHHHEEEEECCCCCCCCCCCCCCCEEEEEEECCCCEEEEEEEEECCCCCC
EGLRPDEVVKTQGQNFNHLTDDLYSEINKGNFPKWDLMVKVLRPEDLNKFDYNPLDATKM
CCCCCHHHHHHCCCCCCHHHHHHHHHHCCCCCCCHHHEEEEECCCCCCCCCCCCCCHHHH
WLDVPETKVGTMTLNRVPDNFFQETEQAAFAPSNLIPGIEPSEDKLLQGRIFSYADTQLY
EEECCCCCCCEEECCCCCCHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHHHHHHHHH
RLGANLSQLPINQPKMAVANHNQEGAANYGRTSSDVNYQPSTKLALAEDHRYRAVQTPLS
HHCCCHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCCEEECCCCC
GTVLQAVIAKQDNFTQAGVLYRSLSKQDKRDLITNLSADLGKVTDSHVKHQMLSYFYQAD
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KDFGKRLTQAVAGDLNEVKKLANM
HHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10952301 [H]