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The map label for this gene is trkH [H]

Identifier: 157959851

GI number: 157959851

Start: 24810

End: 26267

Strand: Direct

Name: trkH [H]

Synonym: Spea_0021

Alternate gene names: 157959851

Gene position: 24810-26267 (Clockwise)

Preceding gene: 157959850

Following gene: 157959852

Centisome position: 0.48

GC content: 47.81

Gene sequence:

>1458_bases
ATGCAATATCGAACAATTATAAGAATCACAGGCCTGTTAATGGGGCTGTTTTCTTTATCTTTACTTCCTCCAGCCCTTGT
CGCCGTTATCTATAAAGATGGCGGTGGTATGGCCTTTATTCAGGCATTTGTGTTGTGCCTGATCTTGGGCTTTGGACTTT
GGTACCCTAACCGTGCACACCGCAAGGACTTGCGGACCCGAGAGGGCTTCCTATTGGTAGTGATGTTTTGGGTGGTACTG
GGCTCCATTGGTGCCGTGCCATTTATCTTCTCTGGTCAACCCTCTCTCAGTTTAACCGACAGTTTCTTTGAATCTTTTTC
GGCGCTGACTACCACTGGTGCCACGGTGATTGTGGGTCTAGATAGTCTGCCCAAGGCGATTCTATTCTATCGACATCTAC
TACAGTGGCTAGGTGGTATGGGGATCATCGTACTTGCTGTGGCGATTCTACCCGTACTCGGTGTAGGAGGCATGCAGCTG
TATCGAGCTGAAATGCCGGGGCCAGTGAAAGACAGTAAGATGACGCCGAGGATTGCCGAGACCGCCAAGGCGCTGTGGTA
TATCTATTTAGCGCTAACGGTCGCCTGCGCAGTTGCTTATTGGCTGGCGGGAATGGATACATTTGACGCTATCTGTCACT
CATTCTCGACCATTGCGATTGGTGGTTTCTCTACTCATGATGCCAGTATGGGTTACTTCGATAGCCCTACAATCAACATG
ATTTGCGTGGTGTTCCTATTGATTGCTGCGCTCAATTTTAGTCTGCACTTTGCGGCATTTTCTCGTCGCGGTATTAACCT
GCGAGTTTATTTTCGCGACGCAGAATTTAAGGTGTTGATCGCTATTCAGTTGGTGCTAACGGCTATCTGTTTTGTCACCC
TCTATGGCTCAGGGATCTATGATTCGGCCGAGGAAACCTTCGATTACGCTCTGTTTCAGGCGGTATCAATTTCAACTACC
GCAGGCTTCGGCACTGAAAGTTTCCATGCTTGGCCTTTGTTCTTACCGATCCTACTGATTTTTTCGAGTTTTATAGGTGG
CAGCGGTGGCTCAACCGCAGGTGGTATTAAAGTCATTCGAGTGATTCTATTGCTGCTACAAGGCTCGCGTGAACTTAAGC
GTCTAGTTCATCCTCGTGGCATGTTCTCTATTCGAATCAGCGGTAACGCACTGCCAGATAGGGTTATCGATGCGGTCTGG
GGGTTCTTCTCGGCTTATGCTTTGGTGTTTGTTGTTTGCATGTTGATCTTGATGGCTTTGGGAATGGATGCCATCACAGC
TTTTAGTGCAACGGCGGCTTGTTTGAACAACCTCGGCCCAGGCTTAGGTGAGGTTGCTAGTAACTACGCCAGTATCGGTG
ATGGTGAAAAATGGGTACTGCTATTCGCCATGCTATTCGGTCGTTTAGAAGTGTTTACTTTACTTATTTTGTTTACGCCA
ACATTCTGGAAAAACTAA

Upstream 100 bases:

>100_bases
ATGGATTAACAAGTTTTTTCAAGCTTGATAATCGGTTATGAACATTCATTATTAAGTGTGCGAGAATGCGCTATAGCATA
AGCGCTAGTGATGGGAATCA

Downstream 100 bases:

>100_bases
ATCTTTGTAAAAATACTGACATGGTAACGCTAACTCAGTTAGCGTTAATTATTAGCTAGTATATTGATAAGCGGGTAGGC
CATTAGGCATTGCTTGAATT

Product: TrkH family potassium uptake protein

Products: Proton [Cytoplasm]; K (I) [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MQYRTIIRITGLLMGLFSLSLLPPALVAVIYKDGGGMAFIQAFVLCLILGFGLWYPNRAHRKDLRTREGFLLVVMFWVVL
GSIGAVPFIFSGQPSLSLTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGVGGMQL
YRAEMPGPVKDSKMTPRIAETAKALWYIYLALTVACAVAYWLAGMDTFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
ICVVFLLIAALNFSLHFAAFSRRGINLRVYFRDAEFKVLIAIQLVLTAICFVTLYGSGIYDSAEETFDYALFQAVSISTT
AGFGTESFHAWPLFLPILLIFSSFIGGSGGSTAGGIKVIRVILLLLQGSRELKRLVHPRGMFSIRISGNALPDRVIDAVW
GFFSAYALVFVVCMLILMALGMDAITAFSATAACLNNLGPGLGEVASNYASIGDGEKWVLLFAMLFGRLEVFTLLILFTP
TFWKN

Sequences:

>Translated_485_residues
MQYRTIIRITGLLMGLFSLSLLPPALVAVIYKDGGGMAFIQAFVLCLILGFGLWYPNRAHRKDLRTREGFLLVVMFWVVL
GSIGAVPFIFSGQPSLSLTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGVGGMQL
YRAEMPGPVKDSKMTPRIAETAKALWYIYLALTVACAVAYWLAGMDTFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
ICVVFLLIAALNFSLHFAAFSRRGINLRVYFRDAEFKVLIAIQLVLTAICFVTLYGSGIYDSAEETFDYALFQAVSISTT
AGFGTESFHAWPLFLPILLIFSSFIGGSGGSTAGGIKVIRVILLLLQGSRELKRLVHPRGMFSIRISGNALPDRVIDAVW
GFFSAYALVFVVCMLILMALGMDAITAFSATAACLNNLGPGLGEVASNYASIGDGEKWVLLFAMLFGRLEVFTLLILFTP
TFWKN
>Mature_485_residues
MQYRTIIRITGLLMGLFSLSLLPPALVAVIYKDGGGMAFIQAFVLCLILGFGLWYPNRAHRKDLRTREGFLLVVMFWVVL
GSIGAVPFIFSGQPSLSLTDSFFESFSALTTTGATVIVGLDSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGVGGMQL
YRAEMPGPVKDSKMTPRIAETAKALWYIYLALTVACAVAYWLAGMDTFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
ICVVFLLIAALNFSLHFAAFSRRGINLRVYFRDAEFKVLIAIQLVLTAICFVTLYGSGIYDSAEETFDYALFQAVSISTT
AGFGTESFHAWPLFLPILLIFSSFIGGSGGSTAGGIKVIRVILLLLQGSRELKRLVHPRGMFSIRISGNALPDRVIDAVW
GFFSAYALVFVVCMLILMALGMDAITAFSATAACLNNLGPGLGEVASNYASIGDGEKWVLLFAMLFGRLEVFTLLILFTP
TFWKN

Specific function: Low-affinity potassium transport system. Interacts with trk system potassium uptake protein trkA and requires trkE for transport activity [H]

COG id: COG0168

COG function: function code P; Trk-type K+ transport systems, membrane components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trkH potassium transport family [H]

Homologues:

Organism=Escherichia coli, GI48994987, Length=485, Percent_Identity=63.9175257731959, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1787626, Length=484, Percent_Identity=41.9421487603306, Blast_Score=402, Evalue=1e-113,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003445
- InterPro:   IPR004772 [H]

Pfam domain/function: PF02386 TrkH [H]

EC number: NA

Molecular weight: Translated: 52813; Mature: 52813

Theoretical pI: Translated: 8.26; Mature: 8.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQYRTIIRITGLLMGLFSLSLLPPALVAVIYKDGGGMAFIQAFVLCLILGFGLWYPNRAH
CCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHH
RKDLRTREGFLLVVMFWVVLGSIGAVPFIFSGQPSLSLTDSFFESFSALTTTGATVIVGL
HHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEC
DSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGVGGMQLYRAEMPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKALWYIYLALTVACAVAYWLAGMDTFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHH
ICVVFLLIAALNFSLHFAAFSRRGINLRVYFRDAEFKVLIAIQLVLTAICFVTLYGSGIY
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
DSAEETFDYALFQAVSISTTAGFGTESFHAWPLFLPILLIFSSFIGGSGGSTAGGIKVIR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VILLLLQGSRELKRLVHPRGMFSIRISGNALPDRVIDAVWGFFSAYALVFVVCMLILMAL
HHHHHHCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMDAITAFSATAACLNNLGPGLGEVASNYASIGDGEKWVLLFAMLFGRLEVFTLLILFTP
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWKN
HHCCC
>Mature Secondary Structure
MQYRTIIRITGLLMGLFSLSLLPPALVAVIYKDGGGMAFIQAFVLCLILGFGLWYPNRAH
CCCHHHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCHHHHHHHHHHHHHHHHCCCCCHHH
RKDLRTREGFLLVVMFWVVLGSIGAVPFIFSGQPSLSLTDSFFESFSALTTTGATVIVGL
HHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEEC
DSLPKAILFYRHLLQWLGGMGIIVLAVAILPVLGVGGMQLYRAEMPGPVKDSKMTPRIAE
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCHHHH
TAKALWYIYLALTVACAVAYWLAGMDTFDAICHSFSTIAIGGFSTHDASMGYFDSPTINM
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEECCCCCCCCCCCCCCCCHHHH
ICVVFLLIAALNFSLHFAAFSRRGINLRVYFRDAEFKVLIAIQLVLTAICFVTLYGSGIY
HHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCC
DSAEETFDYALFQAVSISTTAGFGTESFHAWPLFLPILLIFSSFIGGSGGSTAGGIKVIR
CCHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
VILLLLQGSRELKRLVHPRGMFSIRISGNALPDRVIDAVWGFFSAYALVFVVCMLILMAL
HHHHHHCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GMDAITAFSATAACLNNLGPGLGEVASNYASIGDGEKWVLLFAMLFGRLEVFTLLILFTP
CHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
TFWKN
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; K (I) [Periplasm] [C]

Specific reaction: Proton [Periplasm] + K (I) [Periplasm] = Proton [Cytoplasm] + K (I) [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]