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The map label for this gene is tag [H]

Identifier: 157959838

GI number: 157959838

Start: 10686

End: 11246

Strand: Direct

Name: tag [H]

Synonym: Spea_0008

Alternate gene names: 157959838

Gene position: 10686-11246 (Clockwise)

Preceding gene: 157959835

Following gene: 157959849

Centisome position: 0.21

GC content: 41.0

Gene sequence:

>561_bases
ATGGAAGTAACGCGTTGTGGCTGGGTTAGTAACGATCCCATTTATCAAGAGTACCATGACAGGGTGTGGGGAAGGCCTGT
TTATGATAGCCAAGAGTTATTTGCGAAGCTTTGTCTCGACGGTCAGCAGGCGGGTTTATCTTGGATTACCATACTAAAGA
AACAGCAAAATTATGAGGCTGCATTTGCTAATTTTGATCCTAAAGTTATCGCAACTTTTGATGATGCAAAAATAGAGGAA
TTACTGCAAAACCCTGGCATTGTACGTAATAGGCTTAAGGTTAATTCGATCATAAAAAATGCTAAAGGCTATATGGCTTA
TGTCGAGCAGGGTAATGATTTTTCAGCGTTTTTGTGGAGCTTTGTAGGGGGCGCGCCAAAGACTAATCATTTTATATCAA
TGAATGAATTACCTGTACAGACCCCAGAGTCAGAAGCCATGTCTAAGGCCTTAAAGAAGATGGGTTTTAACTTCGTCGGC
CCCACTATTTGTTATGCCTTTATGCAAGCCGTTGGCATGGTAAATGACCACACCACGGACTGTTTTTGTTATCAAAAATA
A

Upstream 100 bases:

>100_bases
CTGGAAGCTCTAATAGAAAATGGGATCAATTATACCTTGTAGAATAACGCTTATGTAGGTTATTTTTTATCTGGTTGGTT
AAAAACTCAGGAATTGGACT

Downstream 100 bases:

>100_bases
CCCATATAGCCTAAGGATTTAAGGCTGAGTCATTACAAGTTTTGATGGGTCTTCAGAATGTAAATAGATGGCTTTAAATT
CCACTTCGCCAGTAGAGTTA

Product: DNA-3-methyladenine glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 186; Mature: 186

Protein sequence:

>186_residues
MEVTRCGWVSNDPIYQEYHDRVWGRPVYDSQELFAKLCLDGQQAGLSWITILKKQQNYEAAFANFDPKVIATFDDAKIEE
LLQNPGIVRNRLKVNSIIKNAKGYMAYVEQGNDFSAFLWSFVGGAPKTNHFISMNELPVQTPESEAMSKALKKMGFNFVG
PTICYAFMQAVGMVNDHTTDCFCYQK

Sequences:

>Translated_186_residues
MEVTRCGWVSNDPIYQEYHDRVWGRPVYDSQELFAKLCLDGQQAGLSWITILKKQQNYEAAFANFDPKVIATFDDAKIEE
LLQNPGIVRNRLKVNSIIKNAKGYMAYVEQGNDFSAFLWSFVGGAPKTNHFISMNELPVQTPESEAMSKALKKMGFNFVG
PTICYAFMQAVGMVNDHTTDCFCYQK
>Mature_186_residues
MEVTRCGWVSNDPIYQEYHDRVWGRPVYDSQELFAKLCLDGQQAGLSWITILKKQQNYEAAFANFDPKVIATFDDAKIEE
LLQNPGIVRNRLKVNSIIKNAKGYMAYVEQGNDFSAFLWSFVGGAPKTNHFISMNELPVQTPESEAMSKALKKMGFNFVG
PTICYAFMQAVGMVNDHTTDCFCYQK

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=180, Percent_Identity=52.7777777777778, Blast_Score=217, Evalue=4e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21133; Mature: 21133

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVTRCGWVSNDPIYQEYHDRVWGRPVYDSQELFAKLCLDGQQAGLSWITILKKQQNYEA
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCHH
AFANFDPKVIATFDDAKIEELLQNPGIVRNRLKVNSIIKNAKGYMAYVEQGNDFSAFLWS
HHCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
FVGGAPKTNHFISMNELPVQTPESEAMSKALKKMGFNFVGPTICYAFMQAVGMVNDHTTD
HHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
CFCYQK
EEEECC
>Mature Secondary Structure
MEVTRCGWVSNDPIYQEYHDRVWGRPVYDSQELFAKLCLDGQQAGLSWITILKKQQNYEA
CCCCCCCCCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCHHHHHHHHHHCCCHH
AFANFDPKVIATFDDAKIEELLQNPGIVRNRLKVNSIIKNAKGYMAYVEQGNDFSAFLWS
HHCCCCCEEEEEECHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHHHH
FVGGAPKTNHFISMNELPVQTPESEAMSKALKKMGFNFVGPTICYAFMQAVGMVNDHTTD
HHCCCCCCCCEEEECCCCCCCCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCC
CFCYQK
EEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]