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The map label for this gene is ywlC [H]

Identifier: 157826326

GI number: 157826326

Start: 1179948

End: 1180886

Strand: Reverse

Name: ywlC [H]

Synonym: A1C_06575

Alternate gene names: 157826326

Gene position: 1180886-1179948 (Counterclockwise)

Preceding gene: 157826327

Following gene: 157826321

Centisome position: 95.92

GC content: 37.27

Gene sequence:

>939_bases
ATGGTTAGTAAAGCAGTTCAATTTATAAAATCAGGTAAAGTAGTAGTATTCCCAACCGAAACAGTGTATGGAATCGGAGC
GGATGCTACTAATAATGAAGCTTGTTTAAAGATTTTTCAGTTTAAAAATCGTCCTGCTAGTAATCCGCTTATTGTGCATG
TCTTCTCCATAGAGCAAGCAAAAGAAATAGGCGAGTTTAATGATTTAGCTATAAAAATAGCAGAAAAATTTTGGTCTGGA
CCATTATCTATAGTTGTCCCTTTAAAAGAGAATGCCAATATTGCCCCTAGTGCAGCTGCAGGACTAAATACCATAGCACT
TCGGATACCGTCTTACCCTGTAGCATTAGAGCTTATCAGACAATCAGGCGTGCCTATAGCCGCCCCAAGTGCTAACCCTT
CAAACTATATTAGTCCGACTAACGCTGAGCATGTCACAAAACATTTTAAGGATAATCAGGAAATTTTTATTTTAGCACCT
GAAATCTATCAATCTGAATATGGTCTAGAGTCAACGATAATTGATACTACAACCGCTACTCCTACTATTCTTAGAGAAGG
GTTTATAACTGTTGAAATTTTAGAAGAAGTACTTAGGGTAAAAGTGTTAAAAGCATCAGAAACAAGTGCTATAAAAGCTC
CAGGCATGCTTGCGAAACACTATTCACCAAAAGTACCGATCAGGCTAAATGCTATAAATTTAGAGTATAACGAAATCAGC
GTCAATTTTGGTAATAGCAATCTTACGGGAAGATTTTCATTAAATCTCAGTACCAAGGGCAATCTTATAGAAGCTGCTGC
AAATCTTTATGCGTATTTAAGAATTCTTGACGACTATGCTGCAGCTCATGATGTAAGCGGTATAGCAGTTGCGCCTATAC
CTCAAGAAAATATTGGTGCTGCAATTAATGATCGCCTAAAACGTGCCGCAAAATCATAA

Upstream 100 bases:

>100_bases
TGCTAAGTTTAACCGCTTATGACTGAAACTTTCTTATGTAATTCACGCGACAGCGGGAATCCATTAAGCAGATATATAAC
AAAACCAAAATAACTAAATA

Downstream 100 bases:

>100_bases
ATTTCGGCGTTCTATTCTCCTTAATAGCTTTTTGATGATATTTGGTCATTACATAATTATCATGTGAGGTTAGATAATCA
TCGTTATTCATAATTTCAAA

Product: hypothetical protein

Products: NA

Alternate protein names: t(6)A37 threonylcarbamoyladenosine biosynthesis protein YwlC [H]

Number of amino acids: Translated: 312; Mature: 312

Protein sequence:

>312_residues
MVSKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKNRPASNPLIVHVFSIEQAKEIGEFNDLAIKIAEKFWSG
PLSIVVPLKENANIAPSAAAGLNTIALRIPSYPVALELIRQSGVPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAP
EIYQSEYGLESTIIDTTTATPTILREGFITVEILEEVLRVKVLKASETSAIKAPGMLAKHYSPKVPIRLNAINLEYNEIS
VNFGNSNLTGRFSLNLSTKGNLIEAAANLYAYLRILDDYAAAHDVSGIAVAPIPQENIGAAINDRLKRAAKS

Sequences:

>Translated_312_residues
MVSKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKNRPASNPLIVHVFSIEQAKEIGEFNDLAIKIAEKFWSG
PLSIVVPLKENANIAPSAAAGLNTIALRIPSYPVALELIRQSGVPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAP
EIYQSEYGLESTIIDTTTATPTILREGFITVEILEEVLRVKVLKASETSAIKAPGMLAKHYSPKVPIRLNAINLEYNEIS
VNFGNSNLTGRFSLNLSTKGNLIEAAANLYAYLRILDDYAAAHDVSGIAVAPIPQENIGAAINDRLKRAAKS
>Mature_312_residues
MVSKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKNRPASNPLIVHVFSIEQAKEIGEFNDLAIKIAEKFWSG
PLSIVVPLKENANIAPSAAAGLNTIALRIPSYPVALELIRQSGVPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAP
EIYQSEYGLESTIIDTTTATPTILREGFITVEILEEVLRVKVLKASETSAIKAPGMLAKHYSPKVPIRLNAINLEYNEIS
VNFGNSNLTGRFSLNLSTKGNLIEAAANLYAYLRILDDYAAAHDVSGIAVAPIPQENIGAAINDRLKRAAKS

Specific function: Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine (Probable) [H]

COG id: COG0009

COG function: function code J; Putative translation factor (SUA5)

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 YrdC-like domain [H]

Homologues:

Organism=Escherichia coli, GI2367210, Length=152, Percent_Identity=25, Blast_Score=65, Evalue=5e-12,
Organism=Saccharomyces cerevisiae, GI6321269, Length=373, Percent_Identity=31.6353887399464, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI78707274, Length=202, Percent_Identity=28.2178217821782, Blast_Score=69, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017945
- InterPro:   IPR005145
- InterPro:   IPR004388
- InterPro:   IPR006070
- InterPro:   IPR010923 [H]

Pfam domain/function: PF03481 SUA5; PF01300 Sua5_yciO_yrdC [H]

EC number: NA

Molecular weight: Translated: 33785; Mature: 33785

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: PS51163 YRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVSKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKNRPASNPLIVHVFSIEQA
CHHHHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHEEEHHCCCCCCCCEEEEEEEHHHH
KEIGEFNDLAIKIAEKFWSGPLSIVVPLKENANIAPSAAAGLNTIALRIPSYPVALELIR
HHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHCCCEEEEEECCCCHHHHHHHH
QSGVPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAPEIYQSEYGLESTIIDTTTAT
HCCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHCCCCEEEEECCCCC
PTILREGFITVEILEEVLRVKVLKASETSAIKAPGMLAKHYSPKVPIRLNAINLEYNEIS
HHHHHCCCEEHHHHHHHHHEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEEEEEEEEEEE
VNFGNSNLTGRFSLNLSTKGNLIEAAANLYAYLRILDDYAAAHDVSGIAVAPIPQENIGA
EEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHCCH
AINDRLKRAAKS
HHHHHHHHHHCC
>Mature Secondary Structure
MVSKAVQFIKSGKVVVFPTETVYGIGADATNNEACLKIFQFKNRPASNPLIVHVFSIEQA
CHHHHHHHHHCCCEEEEECCEEEEECCCCCCCHHHHEEEHHCCCCCCCCEEEEEEEHHHH
KEIGEFNDLAIKIAEKFWSGPLSIVVPLKENANIAPSAAAGLNTIALRIPSYPVALELIR
HHCCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCHHCCCEEEEEECCCCHHHHHHHH
QSGVPIAAPSANPSNYISPTNAEHVTKHFKDNQEIFILAPEIYQSEYGLESTIIDTTTAT
HCCCCEECCCCCCCCCCCCCCHHHHHHHHCCCCEEEEECHHHHHHHCCCCEEEEECCCCC
PTILREGFITVEILEEVLRVKVLKASETSAIKAPGMLAKHYSPKVPIRLNAINLEYNEIS
HHHHHCCCEEHHHHHHHHHEEEECCCCCCCCCCCCHHHHCCCCCCCEEEEEEEEEEEEEE
VNFGNSNLTGRFSLNLSTKGNLIEAAANLYAYLRILDDYAAAHDVSGIAVAPIPQENIGA
EEECCCCCEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCHHCCH
AINDRLKRAAKS
HHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]