| Definition | Rickettsia akari str. Hartford, complete genome. |
|---|---|
| Accession | NC_009881 |
| Length | 1,231,060 |
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The map label for this gene is uvrA [H]
Identifier: 157826304
GI number: 157826304
Start: 1157234
End: 1160095
Strand: Reverse
Name: uvrA [H]
Synonym: A1C_06465
Alternate gene names: 157826304
Gene position: 1160095-1157234 (Counterclockwise)
Preceding gene: 157826309
Following gene: 157826300
Centisome position: 94.24
GC content: 35.57
Gene sequence:
>2862_bases ATGAACCAAGAATATATTAAGGTACGCGGGGCTAAAGAGCATAATCTAAAAAATATAAATGTTGATATTCCAAGGAATAA ATTTGTTGTTATCACCGGTCTTAGTGGTTCAGGCAAGTCTTCTTTAGCTTTTGATACTATTTATGCAGAAGGTCAAAGGC GATATGTTGAAAGTTTATCTTCGTATGCAAGGCAATTCTTACATTTACAAAATAAACCTAATGTAGAATCTATTTCCGGA TTATCACCGGCAATTGCAATTGACCAGAAAACTACTTCTAAAAATCCGCGTTCTACGGTTGGAACTATAACGGAAATTTA CGATTATCTTAGGTTATTATATGCAAGGGTAGGTATTCCTTACTCTCCTGCAACCGGTCTTCCGATACATAGCCAAACTG TTTCTGAGATGGTAGATATAATTAACGAACTACCTAAAGGTACGAAAGTATATTTACTCGCTCCTATTGTTAGAGGACAT AAAGGGGAATTTAAGCGTGAAATTATAAATCTGAAAAAGCAAGGCTTTCAGAAATTAATAGTTAACGGGGAAGTTTGCGA AATTGATGATTTGCCGAAACTTGATAAAAATAAGAAACATAATATAGAAGTAATCGTTGATAGAATAGTTCTAGACGAAA GTTTAGGTAATAGGCTTGCAGATAGCTTAGAGAGTTCATTAAATCTTGCTGAAGGTATTACTTATTTGGAAATTGTGGAA TTGCCGTCTGCAGTTAAGAACGAGTTTGAAAAAAATCAGCGTATTACTTTTTCTGAGAAATATTCTTGTCCGGTATCGGG TTTTCAGCTTACGGAAATAGAGCCTCGAATCTTTTCTTTTAATAGCCCTTTTGGAGCGTGTCCTAAATGTGAAGGGATAG GTAAAGAGTTTTTCTTTGATAGAGAATTAATTGTTCCGGATCAAAGAATTTCTATTAAAGACGGTGCAATAGTGCCTTGG GGTAGTACATCTTCTAAATTTATCCTAGAGACATTAAAGGCTCTTGCCGATCATTATAAATTTTCTATTGACGTACCTTT TGTAAGTTTATCACAAAATGTTAAGGATATTTTATTTGAAGGTTCAGGAGAAGAGGCAATAAAGTTTGAATTTCATGACG GTTCTAAAACGCAAATAATAAAACAACCTTTTGCCGGTATAATACCAAGTTTGCAAGAAAAGGACCGTACTATAGAATCG GTTTTAATTAAAGAAGAACTAGCTAAATTTAAGTCAGCACATAAATGTACCGCCTGCTCAGGATTTAGATTAAAAGACGA AGCATTATGCGTTAAAATAGCGAATCTTCATATAGGCGAAGTAGTAGGTATGAGTATTGCAGCCTTGCAAGAATGGTTTA GTAACTTAGAAGAAAAATTAAATAAAAAGCAATTATTTATTGCTGAGCGTATTCTCAAAGAAATTACTGAGAGATTAAAA TTTCTTATGGATGTCGGGCTTGAGTATCTAACGTTATCAAGAGAAGCAGCTACTTTATCGGGAGGGGAAAGTCAGCGTAT TCGTCTTGCATCTCAAATAGGTTCAAGGCTTAGCGGTGTTTTATATGTACTTGATGAGCCGTCTATCGGTCTGCATCAAC GAGATAATACAAGATTAATTCAGACGCTCAAAAGGCTTAGAGATTTAGGTAATACCGTTTTGGTAGTCGAGCATGACGAA GAAACAATGTATGAAGCAGATCATATTATTGATATAGGCCCGGGAGCCGGTATTCACGGCGGTCGTGTTATCGCGGAAGG AAATGCTGAAGAAATAAAGAATTTTGAAGAAAGTATTACAGGTAGATATCTAAGCGGTCGTAAAACAATTAAAGTACCGT CTGAAACAAGAGTAGGGCATGATAATAGGACAATTGAATTACTAGGGGCAGTTTCCAACAATTTAGATAATGTTGATATC AAAATTCCGCTTGGTACGTTTACTGCTATAACAGGAGTATCAGGAAGCGGTAAATCAAGCTTAATGATTCATACTCTATA TCAGGCAGCTTTAAAGCATTTAGAGCCGACTAGCAAAGTCTTTCCAGGCAAATATAGAGAATTAAAAGGACTTGAATATA TTGATAAAATTATCGATATTAATCAATCTCCGATAGGTAGAACTCCTCGTTCAAACCCTGCGACTTATACAGGAGCATTT ACTCATATTAGGGATTGGTTTGTGGCATTACCTGAATCAAAAGCTAGAGGGTATAAAGTAGGCAGATTTTCGTTTAACGT TAAAGGCGGGAGATGTGAAGCATGCCAAGGTGACGGGCTGATTAAAATAGAAATGCATTTCCTACCTGACGTATATGTAA AATGTGATATTTGTAATGGTCATAGATATAATAGAGAAACTCTTGAAATAAAATATAAAGGTAAATCTATTGCTGATATT TTGATGATGACAGTAGAAGATGCGATGCAATTTTTTGAGAAAATCCCGTTAATCTATGAAAAATTAATTACCTTAAATGA AGTGGGACTAGGCTATATTAAAATCGGTCAATCTGCTACTACTCTTTCAGGTGGTGAAGCACAACGCGTTAAGCTTGCTA AAGAATTATCAAGACGTTCAACCGGTAAAACACTTTATATACTTGATGAACCGACTACGGGACTGCATATCGACGATATT AATAAATTGCTGAAAGTTTTACATAAGCTTGTTGATATGGGTAATACCGTTTTAGTTATTGAGCATAATCTAGATGTGAT AAAAACAGCAGACTATATTATTGATGTTGGTCCTGAAGGTGGCGACAAAGGCGGTAAGATAGTGGTATGCGGTACTCCTG CAGATATTGCTGCTTGCACGGAAAGCCATACAGGCAGATATTTAAAGCAATATTTGGAATAA
Upstream 100 bases:
>100_bases ACCTATTTTAAAATATTATCATTGCAATAATAAAATAAAAGAGCCTATAATACTACAGGTTTTTTAAAAAATATCTCAAA AATTTTGTAGTGAAGTGATT
Downstream 100 bases:
>100_bases GTCTAATGCTTATGGTCGTGTTGGTGAGTATAGAAGCCTAGAGAAGAAAGTGCGTTTGAGAATTCAGAGTTAGGAGTTAT TTCGTTTGGTATTCCGCTGC
Product: excinuclease ABC subunit A
Products: NA
Alternate protein names: UvrA protein; Excinuclease ABC subunit A [H]
Number of amino acids: Translated: 953; Mature: 953
Protein sequence:
>953_residues MNQEYIKVRGAKEHNLKNINVDIPRNKFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSSYARQFLHLQNKPNVESISG LSPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLYARVGIPYSPATGLPIHSQTVSEMVDIINELPKGTKVYLLAPIVRGH KGEFKREIINLKKQGFQKLIVNGEVCEIDDLPKLDKNKKHNIEVIVDRIVLDESLGNRLADSLESSLNLAEGITYLEIVE LPSAVKNEFEKNQRITFSEKYSCPVSGFQLTEIEPRIFSFNSPFGACPKCEGIGKEFFFDRELIVPDQRISIKDGAIVPW GSTSSKFILETLKALADHYKFSIDVPFVSLSQNVKDILFEGSGEEAIKFEFHDGSKTQIIKQPFAGIIPSLQEKDRTIES VLIKEELAKFKSAHKCTACSGFRLKDEALCVKIANLHIGEVVGMSIAALQEWFSNLEEKLNKKQLFIAERILKEITERLK FLMDVGLEYLTLSREAATLSGGESQRIRLASQIGSRLSGVLYVLDEPSIGLHQRDNTRLIQTLKRLRDLGNTVLVVEHDE ETMYEADHIIDIGPGAGIHGGRVIAEGNAEEIKNFEESITGRYLSGRKTIKVPSETRVGHDNRTIELLGAVSNNLDNVDI KIPLGTFTAITGVSGSGKSSLMIHTLYQAALKHLEPTSKVFPGKYRELKGLEYIDKIIDINQSPIGRTPRSNPATYTGAF THIRDWFVALPESKARGYKVGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVKCDICNGHRYNRETLEIKYKGKSIADI LMMTVEDAMQFFEKIPLIYEKLITLNEVGLGYIKIGQSATTLSGGEAQRVKLAKELSRRSTGKTLYILDEPTTGLHIDDI NKLLKVLHKLVDMGNTVLVIEHNLDVIKTADYIIDVGPEGGDKGGKIVVCGTPADIAACTESHTGRYLKQYLE
Sequences:
>Translated_953_residues MNQEYIKVRGAKEHNLKNINVDIPRNKFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSSYARQFLHLQNKPNVESISG LSPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLYARVGIPYSPATGLPIHSQTVSEMVDIINELPKGTKVYLLAPIVRGH KGEFKREIINLKKQGFQKLIVNGEVCEIDDLPKLDKNKKHNIEVIVDRIVLDESLGNRLADSLESSLNLAEGITYLEIVE LPSAVKNEFEKNQRITFSEKYSCPVSGFQLTEIEPRIFSFNSPFGACPKCEGIGKEFFFDRELIVPDQRISIKDGAIVPW GSTSSKFILETLKALADHYKFSIDVPFVSLSQNVKDILFEGSGEEAIKFEFHDGSKTQIIKQPFAGIIPSLQEKDRTIES VLIKEELAKFKSAHKCTACSGFRLKDEALCVKIANLHIGEVVGMSIAALQEWFSNLEEKLNKKQLFIAERILKEITERLK FLMDVGLEYLTLSREAATLSGGESQRIRLASQIGSRLSGVLYVLDEPSIGLHQRDNTRLIQTLKRLRDLGNTVLVVEHDE ETMYEADHIIDIGPGAGIHGGRVIAEGNAEEIKNFEESITGRYLSGRKTIKVPSETRVGHDNRTIELLGAVSNNLDNVDI KIPLGTFTAITGVSGSGKSSLMIHTLYQAALKHLEPTSKVFPGKYRELKGLEYIDKIIDINQSPIGRTPRSNPATYTGAF THIRDWFVALPESKARGYKVGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVKCDICNGHRYNRETLEIKYKGKSIADI LMMTVEDAMQFFEKIPLIYEKLITLNEVGLGYIKIGQSATTLSGGEAQRVKLAKELSRRSTGKTLYILDEPTTGLHIDDI NKLLKVLHKLVDMGNTVLVIEHNLDVIKTADYIIDVGPEGGDKGGKIVVCGTPADIAACTESHTGRYLKQYLE >Mature_953_residues MNQEYIKVRGAKEHNLKNINVDIPRNKFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLSSYARQFLHLQNKPNVESISG LSPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLYARVGIPYSPATGLPIHSQTVSEMVDIINELPKGTKVYLLAPIVRGH KGEFKREIINLKKQGFQKLIVNGEVCEIDDLPKLDKNKKHNIEVIVDRIVLDESLGNRLADSLESSLNLAEGITYLEIVE LPSAVKNEFEKNQRITFSEKYSCPVSGFQLTEIEPRIFSFNSPFGACPKCEGIGKEFFFDRELIVPDQRISIKDGAIVPW GSTSSKFILETLKALADHYKFSIDVPFVSLSQNVKDILFEGSGEEAIKFEFHDGSKTQIIKQPFAGIIPSLQEKDRTIES VLIKEELAKFKSAHKCTACSGFRLKDEALCVKIANLHIGEVVGMSIAALQEWFSNLEEKLNKKQLFIAERILKEITERLK FLMDVGLEYLTLSREAATLSGGESQRIRLASQIGSRLSGVLYVLDEPSIGLHQRDNTRLIQTLKRLRDLGNTVLVVEHDE ETMYEADHIIDIGPGAGIHGGRVIAEGNAEEIKNFEESITGRYLSGRKTIKVPSETRVGHDNRTIELLGAVSNNLDNVDI KIPLGTFTAITGVSGSGKSSLMIHTLYQAALKHLEPTSKVFPGKYRELKGLEYIDKIIDINQSPIGRTPRSNPATYTGAF THIRDWFVALPESKARGYKVGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVKCDICNGHRYNRETLEIKYKGKSIADI LMMTVEDAMQFFEKIPLIYEKLITLNEVGLGYIKIGQSATTLSGGEAQRVKLAKELSRRSTGKTLYILDEPTTGLHIDDI NKLLKVLHKLVDMGNTVLVIEHNLDVIKTADYIIDVGPEGGDKGGKIVVCGTPADIAACTESHTGRYLKQYLE
Specific function: The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion h
COG id: COG0178
COG function: function code L; Excinuclease ATPase subunit
Gene ontology:
Cell location: Cytoplasm [H]
Metaboloic importance: Non_Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Contains 2 ABC transporter domains [H]
Homologues:
Organism=Escherichia coli, GI2367343, Length=948, Percent_Identity=57.3839662447257, Blast_Score=1103, Evalue=0.0,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR003439 - InterPro: IPR017871 - InterPro: IPR013815 - InterPro: IPR004602 [H]
Pfam domain/function: PF00005 ABC_tran [H]
EC number: NA
Molecular weight: Translated: 106130; Mature: 106130
Theoretical pI: Translated: 7.34; Mature: 7.34
Prosite motif: PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.4 %Cys (Translated Protein) 1.2 %Met (Translated Protein) 2.5 %Cys+Met (Translated Protein) 1.4 %Cys (Mature Protein) 1.2 %Met (Mature Protein) 2.5 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MNQEYIKVRGAKEHNLKNINVDIPRNKFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLS CCCCEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHH SYARQFLHLQNKPNVESISGLSPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLYARVGIP HHHHHHHHCCCCCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC YSPATGLPIHSQTVSEMVDIINELPKGTKVYLLAPIVRGHKGEFKREIINLKKQGFQKLI CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH VNGEVCEIDDLPKLDKNKKHNIEVIVDRIVLDESLGNRLADSLESSLNLAEGITYLEIVE CCCCEECCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH LPSAVKNEFEKNQRITFSEKYSCPVSGFQLTEIEPRIFSFNSPFGACPKCEGIGKEFFFD CCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCHHHEEC RELIVPDQRISIKDGAIVPWGSTSSKFILETLKALADHYKFSIDVPFVSLSQNVKDILFE CEEECCCCCEEECCCEEECCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHCCHHHHEEC GSGEEAIKFEFHDGSKTQIIKQPFAGIIPSLQEKDRTIESVLIKEELAKFKSAHKCTACS CCCCCEEEEEECCCCCHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC GFRLKDEALCVKIANLHIGEVVGMSIAALQEWFSNLEEKLNKKQLFIAERILKEITERLK CCEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FLMDVGLEYLTLSREAATLSGGESQRIRLASQIGSRLSGVLYVLDEPSIGLHQRDNTRLI HHHHCCHHHEEECCHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHH QTLKRLRDLGNTVLVVEHDEETMYEADHIIDIGPGAGIHGGRVIAEGNAEEIKNFEESIT HHHHHHHHCCCEEEEEECCCHHHHCCCCEEECCCCCCCCCCEEEECCCHHHHHHHHHHHC GRYLSGRKTIKVPSETRVGHDNRTIELLGAVSNNLDNVDIKIPLGTFTAITGVSGSGKSS CCEECCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCEEEEECCCCCCCCH LMIHTLYQAALKHLEPTSKVFPGKYRELKGLEYIDKIIDINQSPIGRTPRSNPATYTGAF HHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEECHH THIRDWFVALPESKARGYKVGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVKCDICNG HHHHHHHHCCCCCCCCCEEEEEEEEEECCCEECCCCCCCEEEEEEEECCCEEEEEEEECC HRYNRETLEIKYKGKSIADILMMTVEDAMQFFEKIPLIYEKLITLNEVGLGYIKIGQSAT CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC TLSGGEAQRVKLAKELSRRSTGKTLYILDEPTTGLHIDDINKLLKVLHKLVDMGNTVLVI CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE EHNLDVIKTADYIIDVGPEGGDKGGKIVVCGTPADIAACTESHTGRYLKQYLE ECCCCEEEECCEEEECCCCCCCCCCEEEEECCCHHHHHHHCHHHHHHHHHHCC >Mature Secondary Structure MNQEYIKVRGAKEHNLKNINVDIPRNKFVVITGLSGSGKSSLAFDTIYAEGQRRYVESLS CCCCEEEEECCCCCCCCEEEEECCCCCEEEEEECCCCCCCCEEEHHHHHHHHHHHHHHHH SYARQFLHLQNKPNVESISGLSPAIAIDQKTTSKNPRSTVGTITEIYDYLRLLYARVGIP HHHHHHHHCCCCCCHHHHCCCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCC YSPATGLPIHSQTVSEMVDIINELPKGTKVYLLAPIVRGHKGEFKREIINLKKQGFQKLI CCCCCCCCCCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHH VNGEVCEIDDLPKLDKNKKHNIEVIVDRIVLDESLGNRLADSLESSLNLAEGITYLEIVE CCCCEECCCCCCCCCCCCCCCHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHH LPSAVKNEFEKNQRITFSEKYSCPVSGFQLTEIEPRIFSFNSPFGACPKCEGIGKEFFFD CCHHHHHHHHCCCCEEEECCCCCCCCCEEEEECCCEEEECCCCCCCCCCCCCCCHHHEEC RELIVPDQRISIKDGAIVPWGSTSSKFILETLKALADHYKFSIDVPFVSLSQNVKDILFE CEEECCCCCEEECCCEEECCCCCCHHHHHHHHHHHHHCCEEEEECCCHHHHCCHHHHEEC GSGEEAIKFEFHDGSKTQIIKQPFAGIIPSLQEKDRTIESVLIKEELAKFKSAHKCTACS CCCCCEEEEEECCCCCHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC GFRLKDEALCVKIANLHIGEVVGMSIAALQEWFSNLEEKLNKKQLFIAERILKEITERLK CCEECCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH FLMDVGLEYLTLSREAATLSGGESQRIRLASQIGSRLSGVLYVLDEPSIGLHQRDNTRLI HHHHCCHHHEEECCHHHCCCCCCCHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCHHHH QTLKRLRDLGNTVLVVEHDEETMYEADHIIDIGPGAGIHGGRVIAEGNAEEIKNFEESIT HHHHHHHHCCCEEEEEECCCHHHHCCCCEEECCCCCCCCCCEEEECCCHHHHHHHHHHHC GRYLSGRKTIKVPSETRVGHDNRTIELLGAVSNNLDNVDIKIPLGTFTAITGVSGSGKSS CCEECCCEEEECCCCCCCCCCCCEEEEEEECCCCCCCEEEEEECCCEEEEECCCCCCCCH LMIHTLYQAALKHLEPTSKVFPGKYRELKGLEYIDKIIDINQSPIGRTPRSNPATYTGAF HHHHHHHHHHHHHCCCCCCCCCCHHHHHCCHHHHHHHHCCCCCCCCCCCCCCCCEEECHH THIRDWFVALPESKARGYKVGRFSFNVKGGRCEACQGDGLIKIEMHFLPDVYVKCDICNG HHHHHHHHCCCCCCCCCEEEEEEEEEECCCEECCCCCCCEEEEEEEECCCEEEEEEEECC HRYNRETLEIKYKGKSIADILMMTVEDAMQFFEKIPLIYEKLITLNEVGLGYIKIGQSAT CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCC TLSGGEAQRVKLAKELSRRSTGKTLYILDEPTTGLHIDDINKLLKVLHKLVDMGNTVLVI CCCCCCHHHHHHHHHHHHCCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHCCCCEEEEE EHNLDVIKTADYIIDVGPEGGDKGGKIVVCGTPADIAACTESHTGRYLKQYLE ECCCCEEEECCEEEECCCCCCCCCCEEEEECCCHHHHHHHCHHHHHHHHHHCC
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: DNA [C]
Specific reaction: Protein + DNA = Protein-DNA [C]
General reaction: Hydrolase; Acting on ester bonds [C]
Inhibitor: NA
Structure determination priority: 9.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]