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The map label for this gene is ppiD [H]

Identifier: 157826283

GI number: 157826283

Start: 1138322

End: 1139896

Strand: Reverse

Name: ppiD [H]

Synonym: A1C_06340

Alternate gene names: 157826283

Gene position: 1139896-1138322 (Counterclockwise)

Preceding gene: 157826284

Following gene: 157826282

Centisome position: 92.59

GC content: 28.83

Gene sequence:

>1575_bases
ATGTTAGATAATATTAGAAAAACTGCCGATAGTTTTATAATGCGGGTTTTATTCGCAATGATAGCTTTTGCTTTTGTCGG
ATTTGGTATTAAAGATGTATTAAACGGAAGAAGAAGTGGCGATATTGTTACTTTTTCTCACGTGAAAAATATCTCCCAAG
AAGATTTTTTGCGAGCAAAATCTTTAGCAATTAATGCTATAAGCAAGCAAACGGGAACAAGTTTAACTGACGAAGAAATA
GCACAGTTAAATATTGATAACCAAATCCTTAAAAGACTTGTTTACGATAATGTCTTAGATTATTTAGTTAGCTATTACGA
CTTAGATCTAAGTGATGATACAGTTAAAATTTTAGTTAAAGAATCACCGGTTTTTCAAAATGAGCAAGGTGCTTTTGATA
TAAAAAATTTTAAAGCTTATTTTAGAAATTCTTATATAGATGAAGAAAAATATTTATTAAACTTTAAAGAAAAAGCTTTA
AAAAACATTCTTGTCGGTAGTTTTATAGAAAGTTTCTATGTTCCTAACGCTATGACTGACAATATAGTAGATTATATGGC
TGAAAAAAGAGAAGTAGAATTAATACAAATAGATTTACAAAATAAACCGAAAGATTTACAAATCCCTACCCCTACCGACC
AGCAATTAAAGGTTTTTTACCAAGATAATAAAACCGCGTTTGAGGTACCTGAGAAACGGAGCTTTTCTTATATTAAGGCT
AATATTAAGGATTTAAAAGTCTCAGTTACGCAAGATGAGTTGTTAGAATTTTATAATGAAAATAAAGATGAATTCGGTGA
TCAAAGCTTTGAATTGGTACAAAAACAATTGCATGATTTATTAAAGGCACAAAAAATCGACATACTTAATATGGAGTTTG
CTAAAAAGCTGGAAGATGAGACGGCGGCAGGGTCAAGCTTAGTTGAAATTGCCGAAAAATATAAGCTACCGATACAAAAC
GTTAACTATATAAGTTATGCAGAGCTTATTGAAGATAAAATAATTGCCGAAAGCGCTGATAGTATTTTTGAGCTTTCGGA
AGGAGAATTATCTTATCCTATAGAAGCAGAAGATAAAAGCTATCTTATATTGGTAGAATTAAAATCTATTCAGCCGACAA
AAATACCTGAATTTGATACTATTAAAGAGCAGGTAAATAAAGTTTGGATAAAGCAGAATATCGCTGATGTAAATTTAAAA
ATTATCAAGGATTTAGCAAAGGAATACAATTCAGATCAAGAGAACATAAAAGAGCTTAAAGCTACTGGAATAAAAATAAG
CAAAAAAAGCTATATTAGATCCAAAATGGAAAATGATCTAACATTAACTCCTGAGATATTATTATCAATTTTTAATACTA
AAATAGGAAGTAATACACCTATATTCCAAGTAGGTGATGAAGTATATTTTGCACATATTAAATCTAGAAGTATAGATGAA
TTAACAGCTAAAAATATTCATGTCAATTCAGAAAAAAATATAATATATAATATTAAAAATTCTGTAATTGACGAGCTAAT
TAACTACACAATTATTCAGAATGATATGCAGATAAAAGCTAATTTTAGTAAGTAG

Upstream 100 bases:

>100_bases
TGCAGTCTTGAGAAGCTGCTTAAATGTCATTCCGTAATGCTGAGGATGCATTGCCCCGCGGGTGTGACATATTCTCACTT
AAAAACTTAGACAAAAAATT

Downstream 100 bases:

>100_bases
GGAAATCGTCATTGCGAGGAAATTACGAAGTAATTGACGTAGCAATCCGGTTAAAAATACTAATGTTTAGCATTTAATTA
TTTTTACTGGATTGCCACGT

Product: parvulin-like peptidyl-prolyl isomerase

Products: NA

Alternate protein names: PPIase D; Rotamase D [H]

Number of amino acids: Translated: 524; Mature: 524

Protein sequence:

>524_residues
MLDNIRKTADSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAKSLAINAISKQTGTSLTDEEI
AQLNIDNQILKRLVYDNVLDYLVSYYDLDLSDDTVKILVKESPVFQNEQGAFDIKNFKAYFRNSYIDEEKYLLNFKEKAL
KNILVGSFIESFYVPNAMTDNIVDYMAEKREVELIQIDLQNKPKDLQIPTPTDQQLKVFYQDNKTAFEVPEKRSFSYIKA
NIKDLKVSVTQDELLEFYNENKDEFGDQSFELVQKQLHDLLKAQKIDILNMEFAKKLEDETAAGSSLVEIAEKYKLPIQN
VNYISYAELIEDKIIAESADSIFELSEGELSYPIEAEDKSYLILVELKSIQPTKIPEFDTIKEQVNKVWIKQNIADVNLK
IIKDLAKEYNSDQENIKELKATGIKISKKSYIRSKMENDLTLTPEILLSIFNTKIGSNTPIFQVGDEVYFAHIKSRSIDE
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQIKANFSK

Sequences:

>Translated_524_residues
MLDNIRKTADSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAKSLAINAISKQTGTSLTDEEI
AQLNIDNQILKRLVYDNVLDYLVSYYDLDLSDDTVKILVKESPVFQNEQGAFDIKNFKAYFRNSYIDEEKYLLNFKEKAL
KNILVGSFIESFYVPNAMTDNIVDYMAEKREVELIQIDLQNKPKDLQIPTPTDQQLKVFYQDNKTAFEVPEKRSFSYIKA
NIKDLKVSVTQDELLEFYNENKDEFGDQSFELVQKQLHDLLKAQKIDILNMEFAKKLEDETAAGSSLVEIAEKYKLPIQN
VNYISYAELIEDKIIAESADSIFELSEGELSYPIEAEDKSYLILVELKSIQPTKIPEFDTIKEQVNKVWIKQNIADVNLK
IIKDLAKEYNSDQENIKELKATGIKISKKSYIRSKMENDLTLTPEILLSIFNTKIGSNTPIFQVGDEVYFAHIKSRSIDE
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQIKANFSK
>Mature_524_residues
MLDNIRKTADSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAKSLAINAISKQTGTSLTDEEI
AQLNIDNQILKRLVYDNVLDYLVSYYDLDLSDDTVKILVKESPVFQNEQGAFDIKNFKAYFRNSYIDEEKYLLNFKEKAL
KNILVGSFIESFYVPNAMTDNIVDYMAEKREVELIQIDLQNKPKDLQIPTPTDQQLKVFYQDNKTAFEVPEKRSFSYIKA
NIKDLKVSVTQDELLEFYNENKDEFGDQSFELVQKQLHDLLKAQKIDILNMEFAKKLEDETAAGSSLVEIAEKYKLPIQN
VNYISYAELIEDKIIAESADSIFELSEGELSYPIEAEDKSYLILVELKSIQPTKIPEFDTIKEQVNKVWIKQNIADVNLK
IIKDLAKEYNSDQENIKELKATGIKISKKSYIRSKMENDLTLTPEILLSIFNTKIGSNTPIFQVGDEVYFAHIKSRSIDE
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQIKANFSK

Specific function: PPIases accelerate the folding of proteins. Seems to be involved in the folding of outer membrane proteins [H]

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PpiC domain [H]

Homologues:

Organism=Escherichia coli, GI1786645, Length=487, Percent_Identity=21.5605749486653, Blast_Score=100, Evalue=4e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023058
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 60296; Mature: 60296

Theoretical pI: Translated: 4.68; Mature: 4.68

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDNIRKTADSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEHHHHCCCHHHHHHHH
SLAINAISKQTGTSLTDEEIAQLNIDNQILKRLVYDNVLDYLVSYYDLDLSDDTVKILVK
HHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
ESPVFQNEQGAFDIKNFKAYFRNSYIDEEKYLLNFKEKALKNILVGSFIESFYVPNAMTD
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
NIVDYMAEKREVELIQIDLQNKPKDLQIPTPTDQQLKVFYQDNKTAFEVPEKRSFSYIKA
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCHHHHHC
NIKDLKVSVTQDELLEFYNENKDEFGDQSFELVQKQLHDLLKAQKIDILNMEFAKKLEDE
CHHHEEEEECHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHH
TAAGSSLVEIAEKYKLPIQNVNYISYAELIEDKIIAESADSIFELSEGELSYPIEAEDKS
HCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCC
YLILVELKSIQPTKIPEFDTIKEQVNKVWIKQNIADVNLKIIKDLAKEYNSDQENIKELK
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
ATGIKISKKSYIRSKMENDLTLTPEILLSIFNTKIGSNTPIFQVGDEVYFAHIKSRSIDE
HCCCEECHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCCCHHH
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQIKANFSK
HHHCCEEECCCCCEEEEHHHHHHHHHHHHEEEECCEEEEEECCC
>Mature Secondary Structure
MLDNIRKTADSFIMRVLFAMIAFAFVGFGIKDVLNGRRSGDIVTFSHVKNISQEDFLRAK
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCCCEEEEHHHHCCCHHHHHHHH
SLAINAISKQTGTSLTDEEIAQLNIDNQILKRLVYDNVLDYLVSYYDLDLSDDTVKILVK
HHHHHHHHHHCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEEE
ESPVFQNEQGAFDIKNFKAYFRNSYIDEEKYLLNFKEKALKNILVGSFIESFYVPNAMTD
CCCCCCCCCCCCCHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHH
NIVDYMAEKREVELIQIDLQNKPKDLQIPTPTDQQLKVFYQDNKTAFEVPEKRSFSYIKA
HHHHHHHCCCCEEEEEEEECCCCCCCCCCCCCCCCEEEEEECCCEEECCCCCCCHHHHHC
NIKDLKVSVTQDELLEFYNENKDEFGDQSFELVQKQLHDLLKAQKIDILNMEFAKKLEDE
CHHHEEEEECHHHHHHHHCCCCHHCCCHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHH
TAAGSSLVEIAEKYKLPIQNVNYISYAELIEDKIIAESADSIFELSEGELSYPIEAEDKS
HCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCHHHHCCCCCCCCCCCCCCCCC
YLILVELKSIQPTKIPEFDTIKEQVNKVWIKQNIADVNLKIIKDLAKEYNSDQENIKELK
EEEEEEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCHHHHHHHH
ATGIKISKKSYIRSKMENDLTLTPEILLSIFNTKIGSNTPIFQVGDEVYFAHIKSRSIDE
HCCCEECHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCCEEEECCCEEEEECCCCCHHH
LTAKNIHVNSEKNIIYNIKNSVIDELINYTIIQNDMQIKANFSK
HHHCCEEECCCCCEEEEHHHHHHHHHHHHEEEECCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]