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The map label for this gene is atpA

Identifier: 157826259

GI number: 157826259

Start: 1113777

End: 1115315

Strand: Reverse

Name: atpA

Synonym: A1C_06200

Alternate gene names: 157826259

Gene position: 1115315-1113777 (Counterclockwise)

Preceding gene: 157826260

Following gene: 157826258

Centisome position: 90.6

GC content: 37.69

Gene sequence:

>1539_bases
ATGAAACTAAAGCCTATTGAAGTAGCTGAAATATTACAAAAGGAAATAGCTAATATTAATTGCTTAAGTGAGATTAAAGA
AGTAGGGCAGGTAATCTCGGTAGGTGACGGTATTGCTAAAATTTATGGTCTTGCTAATGTAAAATCTGGTGAAGTAGTAG
AGTTTAAATCCGGTGTTAAGGGGCTTGTTTTAAATTTGGAGAATGATAGCGTCAGTGCTGTAATTATGGGCGATGATAAC
CAAGTACAGCAAGGAGATAATGTCAAAAGAACTAAAGAAGTTTTAGAAGTACCGGTAGGAAAGGCATTGCTTGGTCGTGT
TGTTGATGCTCTTGGTAACCCTATTGATGGCAAAGGCGATATTGCGAGTAAAGAGTACAGACATATCGCGATGAAAGCTC
CGGGAATAATAGAAAGAACGAGTGTAAGCGAACCTGTACAAACCGGAATCAAGGCTATAGATTCGTTAATTCCGATAGGT
AGAGGACAAAGAGAATTAATAATCGGTGATAGACAAACCGGAAAAACAGCGATAGCGGTTGATACTATTATTAATCAAAA
ACAAGCTCATTCACTTACTAATGAAAGCGATAAAATTTATTGTATTTATGTAGCTATTGGGCAAAAAAGATCAAGCGTTG
CACAGATAGTAAAAAAACTAGAAGATGCCGGAGCAATGGACTATACAATCGTTGTTTCGGCTACTGCTTCGGAAGCTGCA
TCTCTTCAATTCATTGCCCCTTATTCTGCCTGTAGTATGGGCGAATATTTTCGTGATAATGGTATGCATGCACTTATTAT
TTATGATGATTTAAGTAAGCATGCCGTCGCATATAGACAAATCTCATTATTACTTAGAAGACCTCCAGGGCGAGAAGCAT
ATCCCGGTGACGTGTTCTATCTGCATTCAAGATTGCTTGAGCGAGCTGCTAAAATGTCAGAGGAAAAAGGCAATGGTTCA
CTTACCGCTCTTCCTATAATCGAGACGCAGGCAGGTGATGTATCTGCCTATATCCCAACGAATGTTATTTCAATTACCGA
CGGTCAAATTTTCTTAGAAAGTGAGTTATTTTATAAAGGTGTAAGACCTGCCGTTAATGTTGGTATTTCAGTAAGCCGTG
TTGGTTCTGCAGCACAAATAAAGGCTATGAAGCAGGTAGCAGGTTCGGTAAAGCTAGAACTTGCTCAATTTAGAGAGCTC
GAGTCTTTCTCGCAATTTGGATCGGATCTAGACCCTGCTACTAAAGCACAAATCGATCACGGTAAAAGATTAGTTGAGAT
ATTAAAACAAGCTCAATATCGTCCTTTGCCGGTAGAAGAACAAATAATAAGTCTTTATGTCGGAACTAAGAAATATTTAA
ATGATGTACCGCTTCAGAAAGTAAAAGAGTTTGAAGATAAAATGCTTACGGAGATAAGATTAAATAAAAAAGATATTTTG
GAATCAATAAAAAATGAGCAACGTATAACCGAAGAAACAGAGCAGAAACTAAAAGCATTTTTAGAGAATTTCGTAAAAGC
CTATTGTGTCATGCCGTGA

Upstream 100 bases:

>100_bases
GGACCCATAAGCAATCTAAAGCTGTATATTATTTGTCATTTTTAACTGGATCCCGTGGTCAAGCCACGGGATGACAACGT
GTAATTAGGAGTCATCCCAC

Downstream 100 bases:

>100_bases
CTTGATCACGGCATTCAGTAAAATAAGTTAAAAATACTGGACCCCGCAGGTACAAGCCACGGGGTGACAATAGAAAACCA
AAAAACTATATGTCACATTT

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha

Number of amino acids: Translated: 512; Mature: 512

Protein sequence:

>512_residues
MKLKPIEVAEILQKEIANINCLSEIKEVGQVISVGDGIAKIYGLANVKSGEVVEFKSGVKGLVLNLENDSVSAVIMGDDN
QVQQGDNVKRTKEVLEVPVGKALLGRVVDALGNPIDGKGDIASKEYRHIAMKAPGIIERTSVSEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTIVVSATASEAA
SLQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEEKGNGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFREL
ESFSQFGSDLDPATKAQIDHGKRLVEILKQAQYRPLPVEEQIISLYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
ESIKNEQRITEETEQKLKAFLENFVKAYCVMP

Sequences:

>Translated_512_residues
MKLKPIEVAEILQKEIANINCLSEIKEVGQVISVGDGIAKIYGLANVKSGEVVEFKSGVKGLVLNLENDSVSAVIMGDDN
QVQQGDNVKRTKEVLEVPVGKALLGRVVDALGNPIDGKGDIASKEYRHIAMKAPGIIERTSVSEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTIVVSATASEAA
SLQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEEKGNGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFREL
ESFSQFGSDLDPATKAQIDHGKRLVEILKQAQYRPLPVEEQIISLYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
ESIKNEQRITEETEQKLKAFLENFVKAYCVMP
>Mature_512_residues
MKLKPIEVAEILQKEIANINCLSEIKEVGQVISVGDGIAKIYGLANVKSGEVVEFKSGVKGLVLNLENDSVSAVIMGDDN
QVQQGDNVKRTKEVLEVPVGKALLGRVVDALGNPIDGKGDIASKEYRHIAMKAPGIIERTSVSEPVQTGIKAIDSLIPIG
RGQRELIIGDRQTGKTAIAVDTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTIVVSATASEAA
SLQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFYLHSRLLERAAKMSEEKGNGS
LTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKGVRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFREL
ESFSQFGSDLDPATKAQIDHGKRLVEILKQAQYRPLPVEEQIISLYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
ESIKNEQRITEETEQKLKAFLENFVKAYCVMP

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family

Homologues:

Organism=Homo sapiens, GI50345984, Length=502, Percent_Identity=64.7410358565737, Blast_Score=689, Evalue=0.0,
Organism=Homo sapiens, GI4757810, Length=502, Percent_Identity=64.7410358565737, Blast_Score=689, Evalue=0.0,
Organism=Homo sapiens, GI19913428, Length=337, Percent_Identity=28.7833827893175, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913426, Length=427, Percent_Identity=24.5901639344262, Blast_Score=111, Evalue=1e-24,
Organism=Homo sapiens, GI32189394, Length=317, Percent_Identity=24.6056782334385, Blast_Score=100, Evalue=5e-21,
Organism=Homo sapiens, GI19913424, Length=255, Percent_Identity=26.2745098039216, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1790172, Length=515, Percent_Identity=56.504854368932, Blast_Score=585, Evalue=1e-168,
Organism=Escherichia coli, GI1790170, Length=356, Percent_Identity=26.4044943820225, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788251, Length=346, Percent_Identity=27.7456647398844, Blast_Score=122, Evalue=8e-29,
Organism=Caenorhabditis elegans, GI71988063, Length=502, Percent_Identity=64.5418326693227, Blast_Score=686, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988080, Length=502, Percent_Identity=64.5418326693227, Blast_Score=684, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71988074, Length=502, Percent_Identity=60.5577689243028, Blast_Score=628, Evalue=1e-180,
Organism=Caenorhabditis elegans, GI17510931, Length=323, Percent_Identity=27.2445820433437, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI17570191, Length=426, Percent_Identity=23.943661971831, Blast_Score=116, Evalue=3e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=317, Percent_Identity=25.2365930599369, Blast_Score=103, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=76, Blast_Score=86, Evalue=5e-17,
Organism=Caenorhabditis elegans, GI71988068, Length=73, Percent_Identity=45.2054794520548, Blast_Score=77, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17565854, Length=254, Percent_Identity=25.9842519685039, Blast_Score=77, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319370, Length=507, Percent_Identity=61.3412228796844, Blast_Score=663, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=334, Percent_Identity=29.0419161676647, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6322581, Length=391, Percent_Identity=24.8081841432225, Blast_Score=106, Evalue=8e-24,
Organism=Drosophila melanogaster, GI24658560, Length=502, Percent_Identity=64.1434262948207, Blast_Score=685, Evalue=0.0,
Organism=Drosophila melanogaster, GI281361666, Length=340, Percent_Identity=28.2352941176471, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI24646341, Length=340, Percent_Identity=28.2352941176471, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI17136796, Length=340, Percent_Identity=28.2352941176471, Blast_Score=123, Evalue=3e-28,
Organism=Drosophila melanogaster, GI28574560, Length=418, Percent_Identity=25.5980861244019, Blast_Score=104, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24638766, Length=317, Percent_Identity=23.9747634069401, Blast_Score=95, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24583988, Length=255, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583986, Length=255, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583984, Length=255, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24583992, Length=255, Percent_Identity=27.0588235294118, Blast_Score=79, Evalue=7e-15,
Organism=Drosophila melanogaster, GI20129479, Length=248, Percent_Identity=28.2258064516129, Blast_Score=74, Evalue=3e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): ATPA_RICAH (A8GPZ6)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493979.1
- ProteinModelPortal:   A8GPZ6
- SMR:   A8GPZ6
- STRING:   A8GPZ6
- GeneID:   5645768
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_06200
- NMPDR:   fig|293614.3.peg.1169
- eggNOG:   COG0056
- HOGENOM:   HBG565875
- OMA:   EFEDKML
- ProtClustDB:   PRK09281
- BioCyc:   RAKA293614:A1C_06200-MONOMER
- HAMAP:   MF_01346
- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- PANTHER:   PTHR15184:SF3
- TIGRFAMs:   TIGR00962

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N; SSF47917 ATPase_a/b_C; SSF50615 ATPase_a/b_N

EC number: =3.6.3.14

Molecular weight: Translated: 56196; Mature: 56196

Theoretical pI: Translated: 6.80; Mature: 6.80

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLKPIEVAEILQKEIANINCLSEIKEVGQVISVGDGIAKIYGLANVKSGEVVEFKSGVK
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECCCCC
GLVLNLENDSVSAVIMGDDNQVQQGDNVKRTKEVLEVPVGKALLGRVVDALGNPIDGKGD
EEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
IASKEYRHIAMKAPGIIERTSVSEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAIAV
CCCHHHHEEEECCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEH
DTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTIVVSATASEAA
HHHHCHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
SLQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFY
CEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMSEEKGNGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKG
HHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCCEEEECHHHHHC
VRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFRELESFSQFGSDLDPATKAQIDH
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GKRLVEILKQAQYRPLPVEEQIISLYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
ESIKNEQRITEETEQKLKAFLENFVKAYCVMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLKPIEVAEILQKEIANINCLSEIKEVGQVISVGDGIAKIYGLANVKSGEVVEFKSGVK
CCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEECCCCC
GLVLNLENDSVSAVIMGDDNQVQQGDNVKRTKEVLEVPVGKALLGRVVDALGNPIDGKGD
EEEEEECCCCEEEEEECCCCCCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCCCC
IASKEYRHIAMKAPGIIERTSVSEPVQTGIKAIDSLIPIGRGQRELIIGDRQTGKTAIAV
CCCHHHHEEEECCCCCEECCCCCHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCEEEEH
DTIINQKQAHSLTNESDKIYCIYVAIGQKRSSVAQIVKKLEDAGAMDYTIVVSATASEAA
HHHHCHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEEECCCCCC
SLQFIAPYSACSMGEYFRDNGMHALIIYDDLSKHAVAYRQISLLLRRPPGREAYPGDVFY
CEEEECCCCHHHHHHHHHCCCCEEEEEECCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHH
LHSRLLERAAKMSEEKGNGSLTALPIIETQAGDVSAYIPTNVISITDGQIFLESELFYKG
HHHHHHHHHHHHCCCCCCCCEEEEEEEEECCCCEEEECCCCEEEEECCCEEEECHHHHHC
VRPAVNVGISVSRVGSAAQIKAMKQVAGSVKLELAQFRELESFSQFGSDLDPATKAQIDH
CCHHHHCCEEHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHH
GKRLVEILKQAQYRPLPVEEQIISLYVGTKKYLNDVPLQKVKEFEDKMLTEIRLNKKDIL
HHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHH
ESIKNEQRITEETEQKLKAFLENFVKAYCVMP
HHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA