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The map label for this gene is nuoG [H]

Identifier: 157826251

GI number: 157826251

Start: 1104700

End: 1106715

Strand: Reverse

Name: nuoG [H]

Synonym: A1C_06150

Alternate gene names: 157826251

Gene position: 1106715-1104700 (Counterclockwise)

Preceding gene: 157826252

Following gene: 157826250

Centisome position: 89.9

GC content: 36.81

Gene sequence:

>2016_bases
ATGATAAAACTGAACGTAGACGGTTTTGAAATAGAAATATCAGAAGGTAGCACCGTTTATCAGGCATGTACACAAGCAGG
TAAAAAAATTCCTCATTTTTGTTATCATGAGCGTTTAAAAATCGCCGGTAATTGCCGTATGTGTTTGGTTGAAATGGAAA
AATCACCAAAGCCTATAGCTTCTTGTGCAATGCCGGTAAGTAACGGTATGGTTATTCACACTGATACACCTATGGTAAAA
AAAGCACGTGAAGGGGTGATGGAGTTTTTACTTATTAACCATCCTTTAGATTGCCCTATTTGTGACCAAGGAGGTGAGTG
TGATTTGCAGGATCAGGCTTTTAGATACGGCAAAGGTACTAATAGATTCCATGAAAATAAGAGATCTATTAAAGATAAAT
ATATGGGACCTCTGATTAAAACAGCGATGACTAGATGTATACAATGCACAAGATGTATTAGATTTGCAAATGATATAGCC
GGAATAGAAGAAATGGGCGCTATCCATCGTGGCGAGCATATGGAGGTAACTTCATATTTAGAGCAAACACTCGATTCTGA
AATTTCCGGTAATATGATAGATATTTGTCCGGTTGGTGCTTTAAATTCCAAACCTTATGCATTTAAAGCTCGTAAATGGG
AACTAAAACATACTGCTAGCATTGGCGTACATGATGCCGAAGGTTCCAATATTCGTATAGATAGTAGAGGCGATGAGGTA
ATGAGAATATTGCCTCGTATTAATGAAGAAATAAATGAGGAATGGATTTCTGATAAAAACCGTTTTAGTTATGACGGTTT
GAAATATCAGCGTTTAGATCGTCCTTATATCAGAAAAAACGGTAAGTTAGTAGAGGCTAGTTGGATTGAAGCCTTAAAGA
CGATAGCGGATAAAATTAAATCCGTAAAACCGGAGAAAATTGCTGCTATTGCAGGTTCTCTTGCTTCTGTTGAAGCAATG
TTTATGCTGAAAACATTAATGCAAAAGCTTGGCTGTAATAATTATAGTGTTAATCAGTTTAACTATAAAATAGATACTAC
GCAGCGAGGAAACTACTTATTTAATACAACTATTGTCGGCGTCAAAAAGGCTGATTTATGTTTACTAATCGGAGCAAATC
CAAGGCAGATAGCTCCGGTGTTAAATAGCCGAATAGGACAAAAAGTGCGTGCCGGTTCATTAAAAGTAGCAAGAATAGGT
GAAGGACATAACCAAACTTATAGAATTCAGGATCTAGGAAGTGATATTAAGATTATTGAGGAGCTAGCTATTGGTGCTCA
TGAGTTTACGAAAGCTTTAAAAGCAGTAAAATATCCGATGATTATAGTAGGTGATGGCGTATATGCAAGAGATGACGGAT
ATGCTATATTGTCGCTTATCCATAAGATAGTGGCTGAATATAATATTATGCGTGATGATTGGAATGGCTTTAATATATTG
TATAATCATGCTTCGATAGTTGGCGGTCTTGACGTTGGTTTGAATAATCCTATTAAGCTTGATGAACTGGAACTCGCTTA
TCTGCTTGGAGCGGACGCCGTCTCATTTGATAAGCTGAAATCGGCTTTTATAGTATATCAAGGACATCATGGGGATTCAG
GTGCTGCAAATGCTGATGTAATTTTACCTGCTGCTGCTTATACAGAGCAGAGCGGAATTTACGTAAATTTAGAAGGAAGA
CCGCAAATAGCAGAAAAAGCAGTATCGCTTGTAGGAACAGCTAAAGAAGATATAGAAATTATTAAAGAGCTTGCCGGTTA
TCTGAAACTAGATATCGGAATGCGTGATTTACAAGAAGTAAGAGCCAAACTTGCTAAAGAATATAAGATATTTGCTAATA
TTGATAAAATTGTAGAGAGTAAATTTGCTAAATTTAGCTCTCAAGATAAGTTATCAAAAGAGCCTATAACTATGGAGCCT
AGTAATTATTACATGACTGACGTAATTAGCAAAAACTCGGTCACTATGGCTAAGTGCGTAGAGGCTAAGGAAGCAAGAAG
TAGGGAGGTAGCATAA

Upstream 100 bases:

>100_bases
GCACTCGCTGTTTGGTATGTACTGCGTGTCGCCATAGGTTTTAAATATATGATAGAGGATCAGACATACCCAAACCCTAT
GACTTATTGGATAAAATAAG

Downstream 100 bases:

>100_bases
AGAGTCGTCATTGCGCGGGAATTACGTAAGTAATTGACGAAGCAATCCAGTAAAAAATTCTGATTTACAGCATTTTTAAA
TCTTTTTCTGGATTGCCACG

Product: NADH dehydrogenase subunit G

Products: NA

Alternate protein names: NADH dehydrogenase I subunit G; NDH-1 subunit G [H]

Number of amino acids: Translated: 671; Mature: 671

Protein sequence:

>671_residues
MIKLNVDGFEIEISEGSTVYQACTQAGKKIPHFCYHERLKIAGNCRMCLVEMEKSPKPIASCAMPVSNGMVIHTDTPMVK
KAREGVMEFLLINHPLDCPICDQGGECDLQDQAFRYGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRFANDIA
GIEEMGAIHRGEHMEVTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDSRGDEV
MRILPRINEEINEEWISDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWIEALKTIADKIKSVKPEKIAAIAGSLASVEAM
FMLKTLMQKLGCNNYSVNQFNYKIDTTQRGNYLFNTTIVGVKKADLCLLIGANPRQIAPVLNSRIGQKVRAGSLKVARIG
EGHNQTYRIQDLGSDIKIIEELAIGAHEFTKALKAVKYPMIIVGDGVYARDDGYAILSLIHKIVAEYNIMRDDWNGFNIL
YNHASIVGGLDVGLNNPIKLDELELAYLLGADAVSFDKLKSAFIVYQGHHGDSGAANADVILPAAAYTEQSGIYVNLEGR
PQIAEKAVSLVGTAKEDIEIIKELAGYLKLDIGMRDLQEVRAKLAKEYKIFANIDKIVESKFAKFSSQDKLSKEPITMEP
SNYYMTDVISKNSVTMAKCVEAKEARSREVA

Sequences:

>Translated_671_residues
MIKLNVDGFEIEISEGSTVYQACTQAGKKIPHFCYHERLKIAGNCRMCLVEMEKSPKPIASCAMPVSNGMVIHTDTPMVK
KAREGVMEFLLINHPLDCPICDQGGECDLQDQAFRYGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRFANDIA
GIEEMGAIHRGEHMEVTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDSRGDEV
MRILPRINEEINEEWISDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWIEALKTIADKIKSVKPEKIAAIAGSLASVEAM
FMLKTLMQKLGCNNYSVNQFNYKIDTTQRGNYLFNTTIVGVKKADLCLLIGANPRQIAPVLNSRIGQKVRAGSLKVARIG
EGHNQTYRIQDLGSDIKIIEELAIGAHEFTKALKAVKYPMIIVGDGVYARDDGYAILSLIHKIVAEYNIMRDDWNGFNIL
YNHASIVGGLDVGLNNPIKLDELELAYLLGADAVSFDKLKSAFIVYQGHHGDSGAANADVILPAAAYTEQSGIYVNLEGR
PQIAEKAVSLVGTAKEDIEIIKELAGYLKLDIGMRDLQEVRAKLAKEYKIFANIDKIVESKFAKFSSQDKLSKEPITMEP
SNYYMTDVISKNSVTMAKCVEAKEARSREVA
>Mature_671_residues
MIKLNVDGFEIEISEGSTVYQACTQAGKKIPHFCYHERLKIAGNCRMCLVEMEKSPKPIASCAMPVSNGMVIHTDTPMVK
KAREGVMEFLLINHPLDCPICDQGGECDLQDQAFRYGKGTNRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRFANDIA
GIEEMGAIHRGEHMEVTSYLEQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDSRGDEV
MRILPRINEEINEEWISDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWIEALKTIADKIKSVKPEKIAAIAGSLASVEAM
FMLKTLMQKLGCNNYSVNQFNYKIDTTQRGNYLFNTTIVGVKKADLCLLIGANPRQIAPVLNSRIGQKVRAGSLKVARIG
EGHNQTYRIQDLGSDIKIIEELAIGAHEFTKALKAVKYPMIIVGDGVYARDDGYAILSLIHKIVAEYNIMRDDWNGFNIL
YNHASIVGGLDVGLNNPIKLDELELAYLLGADAVSFDKLKSAFIVYQGHHGDSGAANADVILPAAAYTEQSGIYVNLEGR
PQIAEKAVSLVGTAKEDIEIIKELAGYLKLDIGMRDLQEVRAKLAKEYKIFANIDKIVESKFAKFSSQDKLSKEPITMEP
SNYYMTDVISKNSVTMAKCVEAKEARSREVA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cyto

COG id: COG1034

COG function: function code C; NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI33519475, Length=685, Percent_Identity=48.4671532846715, Blast_Score=643, Evalue=0.0,
Organism=Escherichia coli, GI145693161, Length=334, Percent_Identity=33.2335329341317, Blast_Score=210, Evalue=3e-55,
Organism=Caenorhabditis elegans, GI17565758, Length=681, Percent_Identity=44.9339207048458, Blast_Score=578, Evalue=1e-165,
Organism=Caenorhabditis elegans, GI32566231, Length=574, Percent_Identity=47.9094076655052, Blast_Score=545, Evalue=1e-155,
Organism=Caenorhabditis elegans, GI193209088, Length=251, Percent_Identity=57.3705179282869, Blast_Score=327, Evalue=1e-89,
Organism=Drosophila melanogaster, GI24640559, Length=687, Percent_Identity=46.2882096069869, Blast_Score=606, Evalue=1e-173,
Organism=Drosophila melanogaster, GI24640557, Length=687, Percent_Identity=46.2882096069869, Blast_Score=606, Evalue=1e-173,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR006656
- InterPro:   IPR000283
- InterPro:   IPR010228
- InterPro:   IPR019574
- InterPro:   IPR015405 [H]

Pfam domain/function: PF09326 DUF1982; PF00111 Fer2; PF00384 Molybdopterin; PF10588 NADH-G_4Fe-4S_3 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 74822; Mature: 74822

Theoretical pI: Translated: 7.79; Mature: 7.79

Prosite motif: PS00641 COMPLEX1_75K_1 ; PS00642 COMPLEX1_75K_2 ; PS00643 COMPLEX1_75K_3 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKLNVDGFEIEISEGSTVYQACTQAGKKIPHFCYHERLKIAGNCRMCLVEMEKSPKPIA
CEEEECCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHEECCCCEEEEEEECCCCCCHH
SCAMPVSNGMVIHTDTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAFRYGKGT
HHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCC
NRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRFANDIAGIEEMGAIHRGEHMEVTSYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHH
EQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDSRGDEV
HHHHHHHHCCCEEEEECCCCCCCCCCEEECEEEEEEECCEECEECCCCCEEEECCCCHHH
MRILPRINEEINEEWISDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWIEALKTIADKIK
HHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCHHHCCCCEEEHHHHHHHHHHHHHHH
SVKPEKIAAIAGSLASVEAMFMLKTLMQKLGCNNYSVNQFNYKIDTTQRGNYLFNTTIVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECEEEEEEECCCCCCEEEEEEEEE
VKKADLCLLIGANPRQIAPVLNSRIGQKVRAGSLKVARIGEGHNQTYRIQDLGSDIKIIE
EEECCEEEEECCCHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCEEEEHHCCCHHHHHH
ELAIGAHEFTKALKAVKYPMIIVGDGVYARDDGYAILSLIHKIVAEYNIMRDDWNGFNIL
HHHCCHHHHHHHHHHHCCCEEEEECCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEE
YNHASIVGGLDVGLNNPIKLDELELAYLLGADAVSFDKLKSAFIVYQGHHGDSGAANADV
EECHHHEECEECCCCCCCCCCHHHEEEECCCCCCCHHHHCCEEEEEECCCCCCCCCCCCE
ILPAAAYTEQSGIYVNLEGRPQIAEKAVSLVGTAKEDIEIIKELAGYLKLDIGMRDLQEV
EEEEHHEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCHHHHHHH
RAKLAKEYKIFANIDKIVESKFAKFSSQDKLSKEPITMEPSNYYMTDVISKNSVTMAKCV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHH
EAKEARSREVA
HHHHHHCCCCC
>Mature Secondary Structure
MIKLNVDGFEIEISEGSTVYQACTQAGKKIPHFCYHERLKIAGNCRMCLVEMEKSPKPIA
CEEEECCCEEEEECCCCHHHHHHHHHCCCCCHHHHHHHHEECCCCEEEEEEECCCCCCHH
SCAMPVSNGMVIHTDTPMVKKAREGVMEFLLINHPLDCPICDQGGECDLQDQAFRYGKGT
HHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCC
NRFHENKRSIKDKYMGPLIKTAMTRCIQCTRCIRFANDIAGIEEMGAIHRGEHMEVTSYL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCHHHHHHH
EQTLDSEISGNMIDICPVGALNSKPYAFKARKWELKHTASIGVHDAEGSNIRIDSRGDEV
HHHHHHHHCCCEEEEECCCCCCCCCCEEECEEEEEEECCEECEECCCCCEEEECCCCHHH
MRILPRINEEINEEWISDKNRFSYDGLKYQRLDRPYIRKNGKLVEASWIEALKTIADKIK
HHHHHHHHHHHHHHHCCCCCCCCCCCEEHHHCCCCHHHCCCCEEEHHHHHHHHHHHHHHH
SVKPEKIAAIAGSLASVEAMFMLKTLMQKLGCNNYSVNQFNYKIDTTQRGNYLFNTTIVG
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECEEEEEEECCCCCCEEEEEEEEE
VKKADLCLLIGANPRQIAPVLNSRIGQKVRAGSLKVARIGEGHNQTYRIQDLGSDIKIIE
EEECCEEEEECCCHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCCEEEEHHCCCHHHHHH
ELAIGAHEFTKALKAVKYPMIIVGDGVYARDDGYAILSLIHKIVAEYNIMRDDWNGFNIL
HHHCCHHHHHHHHHHHCCCEEEEECCEEECCCCHHHHHHHHHHHHHHCCCCCCCCCCEEE
YNHASIVGGLDVGLNNPIKLDELELAYLLGADAVSFDKLKSAFIVYQGHHGDSGAANADV
EECHHHEECEECCCCCCCCCCHHHEEEECCCCCCCHHHHCCEEEEEECCCCCCCCCCCCE
ILPAAAYTEQSGIYVNLEGRPQIAEKAVSLVGTAKEDIEIIKELAGYLKLDIGMRDLQEV
EEEEHHEECCCCEEEEECCCCHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCCHHHHHHH
RAKLAKEYKIFANIDKIVESKFAKFSSQDKLSKEPITMEPSNYYMTDVISKNSVTMAKCV
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEEECCCCEEEEEEECCCCCHHHHHH
EAKEARSREVA
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11557893 [H]