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The map label for this gene is mreB [H]

Identifier: 157826221

GI number: 157826221

Start: 1062875

End: 1063915

Strand: Reverse

Name: mreB [H]

Synonym: A1C_06000

Alternate gene names: 157826221

Gene position: 1063915-1062875 (Counterclockwise)

Preceding gene: 157826222

Following gene: 157826220

Centisome position: 86.42

GC content: 39.67

Gene sequence:

>1041_bases
ATGATAATGAAATTTTTGGAAGGTTTTTTTTCCGGTATGGCCATCGATCTTGGTACGGCAAATACTATTGTATATCAAAA
AAGTCGTGGAATTGTTTTAAGGGAACCTTCTGTTATTGCGTTAATAAAAAAAGACGGTGCTTTTGTACCTTATGCTTATG
GTCATGAAGCAAAAATGATGCTTGGGCGTACTCCTACGGATATTGAAGCAAAAAGACCTTTAAAAGACGGTGTTATTGCC
GATTTTAAGGGTGCAGAGGAAATGATAAAGTATTTTATTAGAATGGTGCATAATCGTCGCTCTTTTTTTGGTCCGACAAT
TGTTATTTGTGTGCCTTCCGGTTCTACGCCGGTTGAGCGTCGTGCTATTCAAGAAGCAGCAGAAAGTGCAGGTGGTAGGG
ATGTTTATTTAATTGAAGAACCTATGGCGGCAGCGATTGGTGCAGGTCTACCCGTAACGGAAGCGACCGGTTCGATGATT
GTTGATATTGGAGGAGGCACTACCGAAGTTGCAGTTTTGTCACTAGGGGGCATAGTATATGCAAGGTCGGTAAGAGTCGG
CGGTGATAAGATGGATGAAGCTATTATCTCATACATAAGAAGGCACTATAACCTATTGATAGGTGAGGCTACTGCCGAAA
AGATAAAGCAAGCAATAGGTACGGCTTATGTAGATGAAAACGCTGAACCGAGAAAAATGGAAATTAAAGGACGTGATTTA
ATTTACGGTATTCCTAAAGAAATGATATTGAACGAAAGACAAATTGCTGATAGTCTAATTGAGCCGGTAAGTCAAATTGT
TGAAGCGGTAAAAGTGGCATTAGAAGCAACGCCTCCTGAATTATCTTCAGATATAGTGGATAAGGGAATTGTATTAACAG
GCGGCGGCTCATTATTACGAAATCTTGATTTTGTTCTTAGTGAAGCCACTAAATTGCCTGTGATAGTTGCAGATGATGCC
CTCTCTTGTGTGGCACTTGGAACAGGAAAAGTACTTGAAGATTTTACAAAGCTAAAACATGTACTATTTAAACAGGATTA
A

Upstream 100 bases:

>100_bases
TTAAACTTCATCTATAATTAAATTTTTATTTACTATGGGATTGTTTGTTTTATTAACAGTTCCATAGGAGCGTTTTTAGA
ATTTAGAGAGCAAAAATAAA

Downstream 100 bases:

>100_bases
CAATGGCAATACTTGCAAATAGAGTAAAAAATTCTTCAAATTCATTAGAATTAATAAGAATAATATCAAATACTCTTAAG
CGTTTTTTTGTTATATTTTG

Product: rod shape-determining protein MreB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 346; Mature: 346

Protein sequence:

>346_residues
MIMKFLEGFFSGMAIDLGTANTIVYQKSRGIVLREPSVIALIKKDGAFVPYAYGHEAKMMLGRTPTDIEAKRPLKDGVIA
DFKGAEEMIKYFIRMVHNRRSFFGPTIVICVPSGSTPVERRAIQEAAESAGGRDVYLIEEPMAAAIGAGLPVTEATGSMI
VDIGGGTTEVAVLSLGGIVYARSVRVGGDKMDEAIISYIRRHYNLLIGEATAEKIKQAIGTAYVDENAEPRKMEIKGRDL
IYGIPKEMILNERQIADSLIEPVSQIVEAVKVALEATPPELSSDIVDKGIVLTGGGSLLRNLDFVLSEATKLPVIVADDA
LSCVALGTGKVLEDFTKLKHVLFKQD

Sequences:

>Translated_346_residues
MIMKFLEGFFSGMAIDLGTANTIVYQKSRGIVLREPSVIALIKKDGAFVPYAYGHEAKMMLGRTPTDIEAKRPLKDGVIA
DFKGAEEMIKYFIRMVHNRRSFFGPTIVICVPSGSTPVERRAIQEAAESAGGRDVYLIEEPMAAAIGAGLPVTEATGSMI
VDIGGGTTEVAVLSLGGIVYARSVRVGGDKMDEAIISYIRRHYNLLIGEATAEKIKQAIGTAYVDENAEPRKMEIKGRDL
IYGIPKEMILNERQIADSLIEPVSQIVEAVKVALEATPPELSSDIVDKGIVLTGGGSLLRNLDFVLSEATKLPVIVADDA
LSCVALGTGKVLEDFTKLKHVLFKQD
>Mature_346_residues
MIMKFLEGFFSGMAIDLGTANTIVYQKSRGIVLREPSVIALIKKDGAFVPYAYGHEAKMMLGRTPTDIEAKRPLKDGVIA
DFKGAEEMIKYFIRMVHNRRSFFGPTIVICVPSGSTPVERRAIQEAAESAGGRDVYLIEEPMAAAIGAGLPVTEATGSMI
VDIGGGTTEVAVLSLGGIVYARSVRVGGDKMDEAIISYIRRHYNLLIGEATAEKIKQAIGTAYVDENAEPRKMEIKGRDL
IYGIPKEMILNERQIADSLIEPVSQIVEAVKVALEATPPELSSDIVDKGIVLTGGGSLLRNLDFVLSEATKLPVIVADDA
LSCVALGTGKVLEDFTKLKHVLFKQD

Specific function: Involved in formation of the rod shape of the cell. May act as a negative regulator of ftsI [H]

COG id: COG1077

COG function: function code D; Actin-like ATPase involved in cell morphogenesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ftsA/mreB family [H]

Homologues:

Organism=Escherichia coli, GI87082236, Length=351, Percent_Identity=58.4045584045584, Blast_Score=394, Evalue=1e-111,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001023
- InterPro:   IPR004753 [H]

Pfam domain/function: PF06723 MreB_Mbl [H]

EC number: NA

Molecular weight: Translated: 37388; Mature: 37388

Theoretical pI: Translated: 5.32; Mature: 5.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIMKFLEGFFSGMAIDLGTANTIVYQKSRGIVLREPSVIALIKKDGAFVPYAYGHEAKMM
CHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEECCCEEEEEECCCCCCCEEECCCCCEE
LGRTPTDIEAKRPLKDGVIADFKGAEEMIKYFIRMVHNRRSFFGPTIVICVPSGSTPVER
ECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCHHHH
RAIQEAAESAGGRDVYLIEEPMAAAIGAGLPVTEATGSMIVDIGGGTTEVAVLSLGGIVY
HHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEECCCEEE
ARSVRVGGDKMDEAIISYIRRHYNLLIGEATAEKIKQAIGTAYVDENAEPRKMEIKGRDL
EEEEECCCCHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHEECCCCCCCEEEECCCEE
IYGIPKEMILNERQIADSLIEPVSQIVEAVKVALEATPPELSSDIVDKGIVLTGGGSLLR
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCHHHHH
NLDFVLSEATKLPVIVADDALSCVALGTGKVLEDFTKLKHVLFKQD
HHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MIMKFLEGFFSGMAIDLGTANTIVYQKSRGIVLREPSVIALIKKDGAFVPYAYGHEAKMM
CHHHHHHHHHCCEEEECCCCCEEEEECCCCEEEECCCEEEEEECCCCCCCEEECCCCCEE
LGRTPTDIEAKRPLKDGVIADFKGAEEMIKYFIRMVHNRRSFFGPTIVICVPSGSTPVER
ECCCCCCCCCCCCCCCCCEECCCCHHHHHHHHHHHHHCCHHHCCCEEEEEECCCCCHHHH
RAIQEAAESAGGRDVYLIEEPMAAAIGAGLPVTEATGSMIVDIGGGTTEVAVLSLGGIVY
HHHHHHHHCCCCCEEEEECCCHHHHHCCCCCCCCCCCCEEEEECCCCCEEEEEECCCEEE
ARSVRVGGDKMDEAIISYIRRHYNLLIGEATAEKIKQAIGTAYVDENAEPRKMEIKGRDL
EEEEECCCCHHHHHHHHHHHHHHHEEEEHHHHHHHHHHHHHHEECCCCCCCEEEECCCEE
IYGIPKEMILNERQIADSLIEPVSQIVEAVKVALEATPPELSSDIVDKGIVLTGGGSLLR
EEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHCCEEEECCHHHHH
NLDFVLSEATKLPVIVADDALSCVALGTGKVLEDFTKLKHVLFKQD
HHHHHHHHHCCCCEEEECCCCEEEEECCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]