| Definition | Rickettsia akari str. Hartford, complete genome. |
|---|---|
| Accession | NC_009881 |
| Length | 1,231,060 |
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The map label for this gene is fabG [H]
Identifier: 157826210
GI number: 157826210
Start: 1053927
End: 1054652
Strand: Direct
Name: fabG [H]
Synonym: A1C_05935
Alternate gene names: 157826210
Gene position: 1053927-1054652 (Clockwise)
Preceding gene: 157826209
Following gene: 157826211
Centisome position: 85.61
GC content: 35.4
Gene sequence:
>726_bases ATGATTGATTTAACAGCTAAAACTGCTTTAATTACGGGAGCTTCAGGAGGTATAGGTGGAGCTATAGCGAGGTTACTGCA CAAACTCGGAAGTCATGTAATTATTAGCGGTAGTCATGAGGAAAAATTAAAATCCCTTGGAAATGTTTTAAAAGATAATT ATACGATAGCAGTATGTAATCTTGCAGATAAAGAAGAGTGCAGCAATTTAATATCTAAAGCACTAAAGCTAGATATTTTA GTATGTAACGCGGGTATTACTAGCGATACACTAGCAATTAGAATGAAAGATGAAGATTTTAACAAAGTTATTGATATTAA TTTAAAAGCAAATTTTATTTTAAATCGTGAAGCAATAAAAAAAATGATGCAAAACAGATATGGACGCATTATTAACATAT CTTCAATAGTAGGAATTTCAGGTAACCCAGGGCAGGCTAATTATTGTGCTTCTAAAGCAGGCTTAATAGGTATGACCAAA TCGCTCTCTTATGAAGTTGCAACCAGAGGAATTACGGTTAATGCAGTAGCTCCAGGATTTATTAAATCAGATATGACCGA TAAACTAAACGCACAACAAAGAGAAGCCATAGTACAAAAAATTCCGCTAGGCACTTACGGTATGCCGGAAGACGTGGCAA ACGCAGTAGCATTTTTAGCAAGCGATCAGGCATCATATATTACCGGCCAAACTATTCACGTAAACGGTGGAATGTTAATG GTGTAA
Upstream 100 bases:
>100_bases TTAAAAGAACATCCACAAATTTCCAACGAAATTGAGAAAATAATACGTGAAAAATCGTCAAAAATTATTAATATAAATCT TGATCAAATGGAGGACGAAA
Downstream 100 bases:
>100_bases AATTTTGTGCTAGCATAAAATAATTTTTTGTGCTAGAAGTGCTTCTAAAGATAAAATGCTATGAATATTTTAAATAAATA TTTATACCAGTTAAAAAAAG
Product: 3-ketoacyl-(acyl-carrier-protein) reductase
Products: NA
Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]
Number of amino acids: Translated: 241; Mature: 241
Protein sequence:
>241_residues MIDLTAKTALITGASGGIGGAIARLLHKLGSHVIISGSHEEKLKSLGNVLKDNYTIAVCNLADKEECSNLISKALKLDIL VCNAGITSDTLAIRMKDEDFNKVIDINLKANFILNREAIKKMMQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTK SLSYEVATRGITVNAVAPGFIKSDMTDKLNAQQREAIVQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM V
Sequences:
>Translated_241_residues MIDLTAKTALITGASGGIGGAIARLLHKLGSHVIISGSHEEKLKSLGNVLKDNYTIAVCNLADKEECSNLISKALKLDIL VCNAGITSDTLAIRMKDEDFNKVIDINLKANFILNREAIKKMMQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTK SLSYEVATRGITVNAVAPGFIKSDMTDKLNAQQREAIVQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM V >Mature_241_residues MIDLTAKTALITGASGGIGGAIARLLHKLGSHVIISGSHEEKLKSLGNVLKDNYTIAVCNLADKEECSNLISKALKLDIL VCNAGITSDTLAIRMKDEDFNKVIDINLKANFILNREAIKKMMQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTK SLSYEVATRGITVNAVAPGFIKSDMTDKLNAQQREAIVQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM V
Specific function: Fatty acid biosynthesis pathway; first reduction step. [C]
COG id: COG1028
COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)
Gene ontology:
Cell location: Cytoplasm [C]
Metaboloic importance: Essential [C]
Operon status: Not Known
Operon components: None
Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]
Homologues:
Organism=Homo sapiens, GI15277342, Length=253, Percent_Identity=37.5494071146245, Blast_Score=160, Evalue=8e-40, Organism=Homo sapiens, GI32483357, Length=244, Percent_Identity=36.0655737704918, Blast_Score=148, Evalue=4e-36, Organism=Homo sapiens, GI40254992, Length=239, Percent_Identity=35.9832635983264, Blast_Score=147, Evalue=7e-36, Organism=Homo sapiens, GI19923817, Length=251, Percent_Identity=35.0597609561753, Blast_Score=127, Evalue=6e-30, Organism=Homo sapiens, GI5031737, Length=245, Percent_Identity=32.2448979591837, Blast_Score=120, Evalue=8e-28, Organism=Homo sapiens, GI126723750, Length=248, Percent_Identity=31.4516129032258, Blast_Score=119, Evalue=3e-27, Organism=Homo sapiens, GI33667109, Length=193, Percent_Identity=32.6424870466321, Blast_Score=102, Evalue=5e-22, Organism=Homo sapiens, GI4504505, Length=254, Percent_Identity=29.5275590551181, Blast_Score=99, Evalue=2e-21, Organism=Homo sapiens, GI7705925, Length=239, Percent_Identity=28.0334728033473, Blast_Score=97, Evalue=1e-20, Organism=Homo sapiens, GI126723191, Length=179, Percent_Identity=32.9608938547486, Blast_Score=93, Evalue=2e-19, Organism=Homo sapiens, GI66933014, Length=216, Percent_Identity=24.537037037037, Blast_Score=90, Evalue=2e-18, Organism=Homo sapiens, GI59889578, Length=220, Percent_Identity=29.0909090909091, Blast_Score=89, Evalue=3e-18, Organism=Homo sapiens, GI4758504, Length=253, Percent_Identity=28.4584980237154, Blast_Score=87, Evalue=9e-18, Organism=Homo sapiens, GI7706318, Length=197, Percent_Identity=28.9340101522843, Blast_Score=85, Evalue=5e-17, Organism=Homo sapiens, GI10190704, Length=258, Percent_Identity=29.8449612403101, Blast_Score=82, Evalue=3e-16, Organism=Homo sapiens, GI226371731, Length=211, Percent_Identity=27.9620853080569, Blast_Score=82, Evalue=5e-16, Organism=Homo sapiens, GI40807363, Length=196, Percent_Identity=29.5918367346939, Blast_Score=80, Evalue=1e-15, Organism=Homo sapiens, GI31542939, Length=247, Percent_Identity=28.3400809716599, Blast_Score=78, Evalue=6e-15, Organism=Homo sapiens, GI4503301, Length=226, Percent_Identity=27.4336283185841, Blast_Score=78, Evalue=9e-15, Organism=Homo sapiens, GI157739938, Length=225, Percent_Identity=27.1111111111111, Blast_Score=73, Evalue=2e-13, Organism=Homo sapiens, GI83715985, Length=253, Percent_Identity=26.4822134387352, Blast_Score=71, Evalue=9e-13, Organism=Homo sapiens, GI109715829, Length=235, Percent_Identity=29.3617021276596, Blast_Score=71, Evalue=1e-12, Organism=Homo sapiens, GI142976729, Length=217, Percent_Identity=29.4930875576037, Blast_Score=69, Evalue=4e-12, Organism=Homo sapiens, GI44680136, Length=210, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI44680133, Length=210, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI17738292, Length=210, Percent_Identity=27.1428571428571, Blast_Score=69, Evalue=5e-12, Organism=Homo sapiens, GI210032110, Length=188, Percent_Identity=26.5957446808511, Blast_Score=67, Evalue=2e-11, Organism=Homo sapiens, GI25282469, Length=156, Percent_Identity=26.9230769230769, Blast_Score=65, Evalue=4e-11, Organism=Homo sapiens, GI225579078, Length=205, Percent_Identity=27.3170731707317, Blast_Score=64, Evalue=8e-11, Organism=Escherichia coli, GI1787335, Length=244, Percent_Identity=50, Blast_Score=236, Evalue=8e-64, Organism=Escherichia coli, GI87082100, Length=250, Percent_Identity=34.4, Blast_Score=134, Evalue=6e-33, Organism=Escherichia coli, GI1789208, Length=248, Percent_Identity=33.0645161290323, Blast_Score=128, Evalue=3e-31, Organism=Escherichia coli, GI87082160, Length=249, Percent_Identity=31.7269076305221, Blast_Score=119, Evalue=2e-28, Organism=Escherichia coli, GI2367365, Length=236, Percent_Identity=34.3220338983051, Blast_Score=117, Evalue=6e-28, Organism=Escherichia coli, GI1790717, Length=249, Percent_Identity=29.3172690763052, Blast_Score=114, Evalue=6e-27, Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=33.469387755102, Blast_Score=108, Evalue=2e-25, Organism=Escherichia coli, GI1788459, Length=244, Percent_Identity=30.7377049180328, Blast_Score=107, Evalue=7e-25, Organism=Escherichia coli, GI1786812, Length=252, Percent_Identity=30.952380952381, Blast_Score=105, Evalue=3e-24, Organism=Escherichia coli, GI1787905, Length=242, Percent_Identity=30.1652892561983, Blast_Score=98, Evalue=6e-22, Organism=Escherichia coli, GI1789378, Length=250, Percent_Identity=31.6, Blast_Score=93, Evalue=1e-20, Organism=Escherichia coli, GI1789057, Length=179, Percent_Identity=34.0782122905028, Blast_Score=92, Evalue=4e-20, Organism=Escherichia coli, GI1787820, Length=223, Percent_Identity=28.6995515695067, Blast_Score=86, Evalue=3e-18, Organism=Escherichia coli, GI1787526, Length=245, Percent_Identity=26.530612244898, Blast_Score=71, Evalue=7e-14, Organism=Escherichia coli, GI1786701, Length=210, Percent_Identity=27.6190476190476, Blast_Score=65, Evalue=4e-12, Organism=Caenorhabditis elegans, GI25147288, Length=244, Percent_Identity=38.1147540983607, Blast_Score=156, Evalue=1e-38, Organism=Caenorhabditis elegans, GI17555706, Length=243, Percent_Identity=36.6255144032922, Blast_Score=150, Evalue=4e-37, Organism=Caenorhabditis elegans, GI17560676, Length=245, Percent_Identity=33.8775510204082, Blast_Score=138, Evalue=2e-33, Organism=Caenorhabditis elegans, GI17561402, Length=249, Percent_Identity=32.5301204819277, Blast_Score=115, Evalue=2e-26, Organism=Caenorhabditis elegans, GI72000259, Length=264, Percent_Identity=31.4393939393939, Blast_Score=111, Evalue=4e-25, Organism=Caenorhabditis elegans, GI17560332, Length=272, Percent_Identity=31.9852941176471, Blast_Score=109, Evalue=1e-24, Organism=Caenorhabditis elegans, GI17562906, Length=267, Percent_Identity=32.2097378277154, Blast_Score=107, Evalue=4e-24, Organism=Caenorhabditis elegans, GI17563726, Length=267, Percent_Identity=30.7116104868914, Blast_Score=106, Evalue=9e-24, Organism=Caenorhabditis elegans, GI17559104, Length=266, Percent_Identity=29.3233082706767, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI193204405, Length=262, Percent_Identity=31.6793893129771, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17562908, Length=263, Percent_Identity=31.1787072243346, Blast_Score=104, Evalue=4e-23, Organism=Caenorhabditis elegans, GI17531453, Length=266, Percent_Identity=31.5789473684211, Blast_Score=104, Evalue=5e-23, Organism=Caenorhabditis elegans, GI115534694, Length=243, Percent_Identity=31.6872427983539, Blast_Score=103, Evalue=6e-23, Organism=Caenorhabditis elegans, GI17562990, Length=268, Percent_Identity=30.9701492537313, Blast_Score=102, Evalue=2e-22, Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=30.7116104868914, Blast_Score=101, Evalue=4e-22, Organism=Caenorhabditis elegans, GI17562904, Length=268, Percent_Identity=30.2238805970149, Blast_Score=100, Evalue=5e-22, Organism=Caenorhabditis elegans, GI17562910, Length=267, Percent_Identity=30.7116104868914, Blast_Score=100, Evalue=9e-22, Organism=Caenorhabditis elegans, GI17551412, Length=265, Percent_Identity=30.9433962264151, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560150, Length=268, Percent_Identity=30.5970149253731, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI71994600, Length=247, Percent_Identity=29.9595141700405, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI17560220, Length=266, Percent_Identity=31.9548872180451, Blast_Score=99, Evalue=2e-21, Organism=Caenorhabditis elegans, GI71994604, Length=245, Percent_Identity=28.9795918367347, Blast_Score=98, Evalue=5e-21, Organism=Caenorhabditis elegans, GI17536025, Length=250, Percent_Identity=32.8, Blast_Score=97, Evalue=7e-21, Organism=Caenorhabditis elegans, GI17536651, Length=250, Percent_Identity=32.4, Blast_Score=95, Evalue=3e-20, Organism=Caenorhabditis elegans, GI17538486, Length=267, Percent_Identity=31.4606741573034, Blast_Score=93, Evalue=2e-19, Organism=Caenorhabditis elegans, GI17568967, Length=185, Percent_Identity=31.3513513513514, Blast_Score=91, Evalue=5e-19, Organism=Caenorhabditis elegans, GI17508651, Length=250, Percent_Identity=30.4, Blast_Score=91, Evalue=6e-19, Organism=Caenorhabditis elegans, GI193203115, Length=243, Percent_Identity=30.4526748971193, Blast_Score=90, Evalue=1e-18, Organism=Caenorhabditis elegans, GI17565030, Length=273, Percent_Identity=31.1355311355311, Blast_Score=89, Evalue=2e-18, Organism=Caenorhabditis elegans, GI193203117, Length=245, Percent_Identity=29.7959183673469, Blast_Score=89, Evalue=3e-18, Organism=Caenorhabditis elegans, GI17538182, Length=252, Percent_Identity=28.5714285714286, Blast_Score=88, Evalue=4e-18, Organism=Caenorhabditis elegans, GI17561272, Length=232, Percent_Identity=28.8793103448276, Blast_Score=87, Evalue=8e-18, Organism=Caenorhabditis elegans, GI17508895, Length=252, Percent_Identity=26.1904761904762, Blast_Score=87, Evalue=9e-18, Organism=Caenorhabditis elegans, GI17544670, Length=273, Percent_Identity=27.1062271062271, Blast_Score=82, Evalue=3e-16, Organism=Caenorhabditis elegans, GI17564282, Length=191, Percent_Identity=29.8429319371728, Blast_Score=75, Evalue=3e-14, Organism=Caenorhabditis elegans, GI17567345, Length=193, Percent_Identity=30.0518134715026, Blast_Score=68, Evalue=4e-12, Organism=Saccharomyces cerevisiae, GI6322861, Length=195, Percent_Identity=34.3589743589744, Blast_Score=102, Evalue=4e-23, Organism=Saccharomyces cerevisiae, GI6324126, Length=251, Percent_Identity=28.2868525896414, Blast_Score=89, Evalue=6e-19, Organism=Saccharomyces cerevisiae, GI6323882, Length=249, Percent_Identity=28.9156626506024, Blast_Score=76, Evalue=5e-15, Organism=Saccharomyces cerevisiae, GI6320089, Length=190, Percent_Identity=32.1052631578947, Blast_Score=68, Evalue=1e-12, Organism=Drosophila melanogaster, GI24639444, Length=246, Percent_Identity=36.5853658536585, Blast_Score=153, Evalue=1e-37, Organism=Drosophila melanogaster, GI21355319, Length=248, Percent_Identity=35.8870967741936, Blast_Score=138, Evalue=3e-33, Organism=Drosophila melanogaster, GI23397609, Length=246, Percent_Identity=32.1138211382114, Blast_Score=117, Evalue=7e-27, Organism=Drosophila melanogaster, GI28571526, Length=255, Percent_Identity=33.3333333333333, Blast_Score=116, Evalue=1e-26, Organism=Drosophila melanogaster, GI24644339, Length=250, Percent_Identity=32.4, Blast_Score=115, Evalue=4e-26, Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=32.1428571428571, Blast_Score=106, Evalue=1e-23, Organism=Drosophila melanogaster, GI24643142, Length=237, Percent_Identity=29.535864978903, Blast_Score=99, Evalue=2e-21, Organism=Drosophila melanogaster, GI24644337, Length=251, Percent_Identity=33.0677290836653, Blast_Score=95, Evalue=5e-20, Organism=Drosophila melanogaster, GI18859837, Length=246, Percent_Identity=31.3008130081301, Blast_Score=92, Evalue=4e-19, Organism=Drosophila melanogaster, GI17737361, Length=256, Percent_Identity=28.515625, Blast_Score=91, Evalue=9e-19, Organism=Drosophila melanogaster, GI24584748, Length=185, Percent_Identity=30.8108108108108, Blast_Score=85, Evalue=5e-17, Organism=Drosophila melanogaster, GI161076933, Length=185, Percent_Identity=30.8108108108108, Blast_Score=84, Evalue=6e-17, Organism=Drosophila melanogaster, GI21358495, Length=200, Percent_Identity=30.5, Blast_Score=80, Evalue=2e-15, Organism=Drosophila melanogaster, GI24584744, Length=246, Percent_Identity=27.2357723577236, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI28574402, Length=202, Percent_Identity=28.2178217821782, Blast_Score=75, Evalue=3e-14, Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=28.3505154639175, Blast_Score=70, Evalue=9e-13, Organism=Drosophila melanogaster, GI24584752, Length=196, Percent_Identity=28.0612244897959, Blast_Score=70, Evalue=1e-12, Organism=Drosophila melanogaster, GI24581726, Length=194, Percent_Identity=26.8041237113402, Blast_Score=67, Evalue=8e-12, Organism=Drosophila melanogaster, GI281364494, Length=197, Percent_Identity=29.4416243654822, Blast_Score=67, Evalue=1e-11, Organism=Drosophila melanogaster, GI28571387, Length=233, Percent_Identity=27.0386266094421, Blast_Score=65, Evalue=4e-11, Organism=Drosophila melanogaster, GI24640442, Length=199, Percent_Identity=26.6331658291457, Blast_Score=65, Evalue=5e-11, Organism=Drosophila melanogaster, GI116007236, Length=236, Percent_Identity=25.8474576271186, Blast_Score=64, Evalue=6e-11,
Paralogues:
None
Copy number: NA
Swissprot (AC and ID): NA
Other databases:
- InterPro: IPR011284 - InterPro: IPR002198 - InterPro: IPR002347 - InterPro: IPR016040 - InterPro: IPR020904 [H]
Pfam domain/function: PF00106 adh_short [H]
EC number: =1.1.1.100 [H]
Molecular weight: Translated: 25656; Mature: 25656
Theoretical pI: Translated: 8.88; Mature: 8.88
Prosite motif: PS00061 ADH_SHORT
Important sites: NA
Signals:
None
Transmembrane regions:
None
Cys/Met content:
1.7 %Cys (Translated Protein) 3.7 %Met (Translated Protein) 5.4 %Cys+Met (Translated Protein) 1.7 %Cys (Mature Protein) 3.7 %Met (Mature Protein) 5.4 %Cys+Met (Mature Protein)
Secondary structure:
>Translated Secondary Structure MIDLTAKTALITGASGGIGGAIARLLHKLGSHVIISGSHEEKLKSLGNVLKDNYTIAVCN CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEE LADKEECSNLISKALKLDILVCNAGITSDTLAIRMKDEDFNKVIDINLKANFILNREAIK CCCHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEEEEEEEECHHHHH KMMQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPGF HHHHHHCCCEEEEEEEEECCCCCCCCCHHHHCCCCEEECCCCCEEEHCCCEEEEECCCCH IKSDMTDKLNAQQREAIVQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM HHCCCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEECCCEEE V C >Mature Secondary Structure MIDLTAKTALITGASGGIGGAIARLLHKLGSHVIISGSHEEKLKSLGNVLKDNYTIAVCN CCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHHHHCCCEEEEEE LADKEECSNLISKALKLDILVCNAGITSDTLAIRMKDEDFNKVIDINLKANFILNREAIK CCCHHHHHHHHHHHHEEEEEEECCCCCCCEEEEEEECCCCCEEEEEEEEEEEEECHHHHH KMMQNRYGRIINISSIVGISGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPGF HHHHHHCCCEEEEEEEEECCCCCCCCCHHHHCCCCEEECCCCCEEEHCCCEEEEECCCCH IKSDMTDKLNAQQREAIVQKIPLGTYGMPEDVANAVAFLASDQASYITGQTIHVNGGMLM HHCCCHHHCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEECCEEEECCCEEE V C
PDB accession: NA
Resolution: NA
Structure class: Alpha Beta
Cofactors: NA
Metal ions: NA
Kcat value (1/min): NA
Specific activity: NA
Km value (mM): NA
Substrates: NA
Specific reaction: NA
General reaction: NA
Inhibitor: NA
Structure determination priority: 10.0
TargetDB status: NA
Availability: NA
References: 11557893 [H]