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The map label for this gene is qacA [H]

Identifier: 157826207

GI number: 157826207

Start: 1051517

End: 1051963

Strand: Reverse

Name: qacA [H]

Synonym: A1C_05920

Alternate gene names: 157826207

Gene position: 1051963-1051517 (Counterclockwise)

Preceding gene: 157826208

Following gene: 157826206

Centisome position: 85.45

GC content: 29.98

Gene sequence:

>447_bases
TTGGCTAAATACGGTATTATGAATATAGCATCCGGTGGAATGCTATTAATTGGCATTGTATTACTAATAATATTTACCTT
ACACCAACTTAAAAGTGATGACCCGCTAGTGAATATGAGTTTATTCTTAATTAGCAATTTTAGTGTAGGAATAATAGTTT
ATTTACTGATTACTTGTGTCTTAGGCTCTATAATGTATCTTATGTCATTATGGTTACAGTTTATCAAAGGGTTAAGTACT
TTGTATGCAGGTCTTTATATGTTGCCTTCAACAGTTTTTGCTTTAATTGTGTCTGTAGTGATGTCATATTTACTTACACG
ATTTACTGCACGTATAATAATATTTAGCGTGCTTATCTTTATTACTATATCATTGATTTTACCTAGTATATTAGCCTATA
GAGATTTATTACCGAATACTATATATCTTGGACTGCTTGGTATATGA

Upstream 100 bases:

>100_bases
GATTCCTGAAGCATCTAACCCCAGTAATGAACCATGGTATTGGATAGGTGTATTTCAATCATTTTTCGGTACAGCAGCTT
TAGTTCAAGATATTAAGATA

Downstream 100 bases:

>100_bases
AGTAGTCTATGCCTCTCTACAACCGTAACAGTTATGATGAATGCAGTATCAGCAGAGAGATCAGGAGGTGCAGCAGCACT
ATAAGAAACAGCATATGAAT

Product: hypothetical protein

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAKYGIMNIASGGMLLIGIVLLIIFTLHQLKSDDPLVNMSLFLISNFSVGIIVYLLITCVLGSIMYLMSLWLQFIKGLST
LYAGLYMLPSTVFALIVSVVMSYLLTRFTARIIIFSVLIFITISLILPSILAYRDLLPNTIYLGLLGI

Sequences:

>Translated_148_residues
MAKYGIMNIASGGMLLIGIVLLIIFTLHQLKSDDPLVNMSLFLISNFSVGIIVYLLITCVLGSIMYLMSLWLQFIKGLST
LYAGLYMLPSTVFALIVSVVMSYLLTRFTARIIIFSVLIFITISLILPSILAYRDLLPNTIYLGLLGI
>Mature_147_residues
AKYGIMNIASGGMLLIGIVLLIIFTLHQLKSDDPLVNMSLFLISNFSVGIIVYLLITCVLGSIMYLMSLWLQFIKGLSTL
YAGLYMLPSTVFALIVSVVMSYLLTRFTARIIIFSVLIFITISLILPSILAYRDLLPNTIYLGLLGI

Specific function: Confers export-mediated resistance against antiseptic and disinfectant compounds such as intercalating dyes, quaternary ammonium salts and diamidines [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196
- InterPro:   IPR005829 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 16404; Mature: 16272

Theoretical pI: Translated: 9.34; Mature: 9.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
5.4 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAKYGIMNIASGGMLLIGIVLLIIFTLHQLKSDDPLVNMSLFLISNFSVGIIVYLLITCV
CCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
LGSIMYLMSLWLQFIKGLSTLYAGLYMLPSTVFALIVSVVMSYLLTRFTARIIIFSVLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITISLILPSILAYRDLLPNTIYLGLLGI
HHHHHHHHHHHHHHHHCCHHHHHHHHCC
>Mature Secondary Structure 
AKYGIMNIASGGMLLIGIVLLIIFTLHQLKSDDPLVNMSLFLISNFSVGIIVYLLITCV
CCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCHHHHHHHHHHHHH
LGSIMYLMSLWLQFIKGLSTLYAGLYMLPSTVFALIVSVVMSYLLTRFTARIIIFSVLIF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ITISLILPSILAYRDLLPNTIYLGLLGI
HHHHHHHHHHHHHHHHCCHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11418146 [H]