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The map label for this gene is tlcE [H]

Identifier: 157826185

GI number: 157826185

Start: 1028688

End: 1030130

Strand: Reverse

Name: tlcE [H]

Synonym: A1C_05810

Alternate gene names: 157826185

Gene position: 1030130-1028688 (Counterclockwise)

Preceding gene: 157826188

Following gene: 157826184

Centisome position: 83.68

GC content: 32.09

Gene sequence:

>1443_bases
GTGCATAATTACGAACTCGGAAAGTTTATTCCGATGAGTGCCTTAATGTTTTGTATTTTATTTAATCAAAATGTTTTACG
AATCTTAAAAGATAGTATTTTAATTTCTGAGATTAGTGCAGAAATAGCAGGTTTTGCTAAAGTTTATTGTGTTACTCCTG
CTGCTGCTTTATTCGTGATTATTTATGCTAAAATGATTAATCATCTTACTTTTGACAAGATCTTTTATTATTTAAGTGCA
TTTTTCATCGGCTTTTTTGTTTTATTTGCCTTTGTTATTTATCCTAATATTCATATTTTTCATGTACATCCAGATAATCT
AGCTGACTGGATGGAACGCTATCCTCATTTTAAGTGGTATATATCATTAGTAGGTAATTGGGGTTATATAGTATATTATA
GTCTTGCCGAGCTTTGGCCTAATATTTTTTACGTATTATTATTTTGGCAGTTTGCTAATGAACTTACTACCACCGAAGAA
GCAAAAAGATTTTATACTCTCTTTTCGCTATTCGGCAACTCTTCTTTAATATTAGTCGGCTTTTTAATGATGAATCTATC
ATCGGAAGATACTATTATTAAGAAGTTTATGAGTATTTCGGATAGTAAAATCACTTTAGTTCAAGTATCCACGACAATGG
TTGCTATCGTTTCTATTGTTTATTGTTTGTTAGTTAGATTTATTAGTAAGAACGTTTTTACTAACCCATTATTTTATGCC
AAAGTAAAAAGCGGTAGATCAACTTCAGCACGGATAGGACTGATTAAAAGCTTTAAATATATTGCAAAATCAAAATATTT
ATGGCTACTTTTAATTTGTTCCGCAGCGTTCGGATTTGCTATTAACTTAGTCGAAGCCGTATGGAAAGCAAAAATTAAGG
AATTATATCCGACTGTAAATACCTATGCTGAATTTAACAGTTTGTATATACTTTGGACAGGCGTTGCAATAATGGTTATG
ACCATCATCGGTAATAACGTTATGCGTATGCATAACTGGTTTGCAGCAGCAGTTATTTCACCAGTTATAATAATGGTGAC
CGGCATTTTGTTCTTTGTACTTATAGTATTTGATCAACAAATTTTATCATTATTTGATGGAGCAATTTTAATGTCACCTC
TTGCTCTTGCCGTTTCGATCGGCGGTATTCAAAATATTTTAGCTAAAGGTACTAAATATTCTATATGGGATACTTCAAGA
GAAATGTTATATATCCCTCTTGATGAGGAGCTTAAAACCAAAGGCAAAGCAGCGGTTGACGTAATAAGTGCAAAAGTTGG
CAAATCCTCTAGCGGTCTTGTACAATCTATTATCTTTACCTTAGTTCCGACTGCTACTTTTACCTCAATCTCACCGATTC
TAATGGTGGTATTTACTTTCGTATGCCTTGCTTGGATTTATGCAGTAAGGAAAATATATTTTGAATATCAAAAAATAGCA
TAA

Upstream 100 bases:

>100_bases
ACATAAAGTACTTAAGTTTTTTTTTTGTCCTTAGGGATTTATAATGCTGAGTACCTCATCACGATCGTTTAAAAGCAAAT
TCAGAGCGGCATTTTGGCCT

Downstream 100 bases:

>100_bases
TGATACTGATGTTGCCTACGTGATACGATTTTCTTGTCATTGTGAGCGACTGTAGGCGTTGTTGCGTGGATCGGTTGTTC
TTCTGTCATCTAAGGACTTG

Product: ADP,ATP carrier protein

Products: NA

Alternate protein names: ADP/ATP translocase 5 [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MHNYELGKFIPMSALMFCILFNQNVLRILKDSILISEISAEIAGFAKVYCVTPAAALFVIIYAKMINHLTFDKIFYYLSA
FFIGFFVLFAFVIYPNIHIFHVHPDNLADWMERYPHFKWYISLVGNWGYIVYYSLAELWPNIFYVLLFWQFANELTTTEE
AKRFYTLFSLFGNSSLILVGFLMMNLSSEDTIIKKFMSISDSKITLVQVSTTMVAIVSIVYCLLVRFISKNVFTNPLFYA
KVKSGRSTSARIGLIKSFKYIAKSKYLWLLLICSAAFGFAINLVEAVWKAKIKELYPTVNTYAEFNSLYILWTGVAIMVM
TIIGNNVMRMHNWFAAAVISPVIIMVTGILFFVLIVFDQQILSLFDGAILMSPLALAVSIGGIQNILAKGTKYSIWDTSR
EMLYIPLDEELKTKGKAAVDVISAKVGKSSSGLVQSIIFTLVPTATFTSISPILMVVFTFVCLAWIYAVRKIYFEYQKIA

Sequences:

>Translated_480_residues
MHNYELGKFIPMSALMFCILFNQNVLRILKDSILISEISAEIAGFAKVYCVTPAAALFVIIYAKMINHLTFDKIFYYLSA
FFIGFFVLFAFVIYPNIHIFHVHPDNLADWMERYPHFKWYISLVGNWGYIVYYSLAELWPNIFYVLLFWQFANELTTTEE
AKRFYTLFSLFGNSSLILVGFLMMNLSSEDTIIKKFMSISDSKITLVQVSTTMVAIVSIVYCLLVRFISKNVFTNPLFYA
KVKSGRSTSARIGLIKSFKYIAKSKYLWLLLICSAAFGFAINLVEAVWKAKIKELYPTVNTYAEFNSLYILWTGVAIMVM
TIIGNNVMRMHNWFAAAVISPVIIMVTGILFFVLIVFDQQILSLFDGAILMSPLALAVSIGGIQNILAKGTKYSIWDTSR
EMLYIPLDEELKTKGKAAVDVISAKVGKSSSGLVQSIIFTLVPTATFTSISPILMVVFTFVCLAWIYAVRKIYFEYQKIA
>Mature_480_residues
MHNYELGKFIPMSALMFCILFNQNVLRILKDSILISEISAEIAGFAKVYCVTPAAALFVIIYAKMINHLTFDKIFYYLSA
FFIGFFVLFAFVIYPNIHIFHVHPDNLADWMERYPHFKWYISLVGNWGYIVYYSLAELWPNIFYVLLFWQFANELTTTEE
AKRFYTLFSLFGNSSLILVGFLMMNLSSEDTIIKKFMSISDSKITLVQVSTTMVAIVSIVYCLLVRFISKNVFTNPLFYA
KVKSGRSTSARIGLIKSFKYIAKSKYLWLLLICSAAFGFAINLVEAVWKAKIKELYPTVNTYAEFNSLYILWTGVAIMVM
TIIGNNVMRMHNWFAAAVISPVIIMVTGILFFVLIVFDQQILSLFDGAILMSPLALAVSIGGIQNILAKGTKYSIWDTSR
EMLYIPLDEELKTKGKAAVDVISAKVGKSSSGLVQSIIFTLVPTATFTSISPILMVVFTFVCLAWIYAVRKIYFEYQKIA

Specific function: Provides the rickettsial cell with host ATP in exchange for rickettsial ADP. This is an obligate exchange system. This energy acquiring activity is an important component of rickettsial parasitism [H]

COG id: COG3202

COG function: function code C; ATP/ADP translocase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ADP/ATP translocase tlc family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004667 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 54587; Mature: 54587

Theoretical pI: Translated: 9.44; Mature: 9.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHNYELGKFIPMSALMFCILFNQNVLRILKDSILISEISAEIAGFAKVYCVTPAAALFVI
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHH
IYAKMINHLTFDKIFYYLSAFFIGFFVLFAFVIYPNIHIFHVHPDNLADWMERYPHFKWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCEEE
ISLVGNWGYIVYYSLAELWPNIFYVLLFWQFANELTTTEEAKRFYTLFSLFGNSSLILVG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
FLMMNLSSEDTIIKKFMSISDSKITLVQVSTTMVAIVSIVYCLLVRFISKNVFTNPLFYA
HHHHCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
KVKSGRSTSARIGLIKSFKYIAKSKYLWLLLICSAAFGFAINLVEAVWKAKIKELYPTVN
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TYAEFNSLYILWTGVAIMVMTIIGNNVMRMHNWFAAAVISPVIIMVTGILFFVLIVFDQQ
HHHHHCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSLFDGAILMSPLALAVSIGGIQNILAKGTKYSIWDTSREMLYIPLDEELKTKGKAAVD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCHHHHHCCHHHHH
VISAKVGKSSSGLVQSIIFTLVPTATFTSISPILMVVFTFVCLAWIYAVRKIYFEYQKIA
HHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MHNYELGKFIPMSALMFCILFNQNVLRILKDSILISEISAEIAGFAKVYCVTPAAALFVI
CCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHEECCHHHHHHHH
IYAKMINHLTFDKIFYYLSAFFIGFFVLFAFVIYPNIHIFHVHPDNLADWMERYPHFKWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHHCCCCEEE
ISLVGNWGYIVYYSLAELWPNIFYVLLFWQFANELTTTEEAKRFYTLFSLFGNSSLILVG
EEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHH
FLMMNLSSEDTIIKKFMSISDSKITLVQVSTTMVAIVSIVYCLLVRFISKNVFTNPLFYA
HHHHCCCCCHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEE
KVKSGRSTSARIGLIKSFKYIAKSKYLWLLLICSAAFGFAINLVEAVWKAKIKELYPTVN
EECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TYAEFNSLYILWTGVAIMVMTIIGNNVMRMHNWFAAAVISPVIIMVTGILFFVLIVFDQQ
HHHHHCCEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILSLFDGAILMSPLALAVSIGGIQNILAKGTKYSIWDTSREMLYIPLDEELKTKGKAAVD
HHHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCEEEEECCHHHHHCCHHHHH
VISAKVGKSSSGLVQSIIFTLVPTATFTSISPILMVVFTFVCLAWIYAVRKIYFEYQKIA
HHHHHCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA