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The map label for this gene is queC

Identifier: 157826116

GI number: 157826116

Start: 966574

End: 967257

Strand: Reverse

Name: queC

Synonym: A1C_05455

Alternate gene names: 157826116

Gene position: 967257-966574 (Counterclockwise)

Preceding gene: 157826117

Following gene: 157826115

Centisome position: 78.57

GC content: 34.94

Gene sequence:

>684_bases
ATGAAAAAAGCAGTTATGTTAGTTAGCGGCGGGGCAGACTCTGCTACGGTTCTTGCAATGGCAAGAGAAATAGGGTATGA
AATTCATTCTATGAGTTTTAATTACGGACAACGTAATAATGCAGAGCTTCGGAAAGTTAAGGAGCTTATAAAAGAATATA
ACGTCAAGCAGCATAAGATTGTTGATATAGATTTACGAGCTTTCGGTGGTTCTGCTTTAACCGACGATAATATAGATGTT
CCGCATTATCATGATGTAAACGCAGTACCTGAAGATGTGCCGGTTACTTACGTGCCTTCTCGTAATACGATATTTTTAAG
CTATGCACTAGGGTATGCAGAAGTAATAGGAGCAAAAGATATTTTTATAGGTGTGCATACAAGCGATTCAGCAAATTATC
CTGATTGTCGTCCTGAATATATTAAATCTTTTGAAAAAATGGCAAATTTAGCAACCAGTATTGGAATACAGGGTCAAAAA
ATTACTATTCATACGCCTTTAATTGATATGACTAAAGAGCAAATAATTAGAACAGGTCTTAAGCTTGGTGTAGATTACAA
AAATACTATATCATGTTATGAACCTACTGAAGATGATTCATCTTGCGGTAATTGCCTTGCTTGCATGATAAGGCTTGATG
CTTTTAAAAAGAATAATATACAAGACCCAATTAAATATGTATGA

Upstream 100 bases:

>100_bases
GTAGATAAACGTGTGTATCGAGCTTTAGTACTTGAAGCACTTAGAGCAAAAATTAGTTTAAATGCTCTAGTATTCCAAAA
ATTAACTTTATCGGTAAACA

Downstream 100 bases:

>100_bases
TAAATACTGCTTGTATTTCAAGAATTGCTCTTTCTTTTTATCAAGGACTCGTGATGCTCACGTGCTATGTGTACGCTCCG
CTCACTCGCCTATCAAAATA

Product: trans-regulatory protein ExsB

Products: NA

Alternate protein names: 7-cyano-7-carbaguanine synthase; PreQ(0) synthase; Queuosine biosynthesis protein queC

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MKKAVMLVSGGADSATVLAMAREIGYEIHSMSFNYGQRNNAELRKVKELIKEYNVKQHKIVDIDLRAFGGSALTDDNIDV
PHYHDVNAVPEDVPVTYVPSRNTIFLSYALGYAEVIGAKDIFIGVHTSDSANYPDCRPEYIKSFEKMANLATSIGIQGQK
ITIHTPLIDMTKEQIIRTGLKLGVDYKNTISCYEPTEDDSSCGNCLACMIRLDAFKKNNIQDPIKYV

Sequences:

>Translated_227_residues
MKKAVMLVSGGADSATVLAMAREIGYEIHSMSFNYGQRNNAELRKVKELIKEYNVKQHKIVDIDLRAFGGSALTDDNIDV
PHYHDVNAVPEDVPVTYVPSRNTIFLSYALGYAEVIGAKDIFIGVHTSDSANYPDCRPEYIKSFEKMANLATSIGIQGQK
ITIHTPLIDMTKEQIIRTGLKLGVDYKNTISCYEPTEDDSSCGNCLACMIRLDAFKKNNIQDPIKYV
>Mature_227_residues
MKKAVMLVSGGADSATVLAMAREIGYEIHSMSFNYGQRNNAELRKVKELIKEYNVKQHKIVDIDLRAFGGSALTDDNIDV
PHYHDVNAVPEDVPVTYVPSRNTIFLSYALGYAEVIGAKDIFIGVHTSDSANYPDCRPEYIKSFEKMANLATSIGIQGQK
ITIHTPLIDMTKEQIIRTGLKLGVDYKNTISCYEPTEDDSSCGNCLACMIRLDAFKKNNIQDPIKYV

Specific function: Catalyzes the ATP-dependent conversion of 7-carboxy-7- deazaguanine (CDG) to 7-cyano-7-deazaguanine (preQ(0))

COG id: COG0603

COG function: function code R; Predicted PP-loop superfamily ATPase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the queC family

Homologues:

Organism=Escherichia coli, GI1786648, Length=221, Percent_Identity=36.1990950226244, Blast_Score=132, Evalue=2e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): QUEC_RICAH (A8GPK3)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493836.1
- ProteinModelPortal:   A8GPK3
- SMR:   A8GPK3
- STRING:   A8GPK3
- GeneID:   5645834
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_05455
- NMPDR:   fig|293614.3.peg.1025
- eggNOG:   COG0603
- HOGENOM:   HBG553284
- OMA:   GWAEVLG
- ProtClustDB:   CLSK871034
- BioCyc:   RAKA293614:A1C_05455-MONOMER
- HAMAP:   MF_01633_B
- InterPro:   IPR018317
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PIRSF:   PIRSF006293
- TIGRFAMs:   TIGR00364

Pfam domain/function: PF06508 ExsB

EC number: NA

Molecular weight: Translated: 25276; Mature: 25276

Theoretical pI: Translated: 6.24; Mature: 6.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKAVMLVSGGADSATVLAMAREIGYEIHSMSFNYGQRNNAELRKVKELIKEYNVKQHKI
CCCEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEE
VDIDLRAFGGSALTDDNIDVPHYHDVNAVPEDVPVTYVPSRNTIFLSYALGYAEVIGAKD
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHCCCE
IFIGVHTSDSANYPDCRPEYIKSFEKMANLATSIGIQGQKITIHTPLIDMTKEQIIRTGL
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHH
KLGVDYKNTISCYEPTEDDSSCGNCLACMIRLDAFKKNNIQDPIKYV
HHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCC
>Mature Secondary Structure
MKKAVMLVSGGADSATVLAMAREIGYEIHSMSFNYGQRNNAELRKVKELIKEYNVKQHKI
CCCEEEEEECCCCHHHHHHHHHHHCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCEEE
VDIDLRAFGGSALTDDNIDVPHYHDVNAVPEDVPVTYVPSRNTIFLSYALGYAEVIGAKD
EEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCEEEECCCCEEEEEEHHHHHHHHCCCE
IFIGVHTSDSANYPDCRPEYIKSFEKMANLATSIGIQGQKITIHTPLIDMTKEQIIRTGL
EEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHH
KLGVDYKNTISCYEPTEDDSSCGNCLACMIRLDAFKKNNIQDPIKYV
HHCCCCCCEEECCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA