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The map label for this gene is ubiA [H]

Identifier: 157826105

GI number: 157826105

Start: 952630

End: 953472

Strand: Reverse

Name: ubiA [H]

Synonym: A1C_05345

Alternate gene names: 157826105

Gene position: 953472-952630 (Counterclockwise)

Preceding gene: 157826108

Following gene: 157826103

Centisome position: 77.45

GC content: 32.27

Gene sequence:

>843_bases
ATGCCAAATAAACTTTTACTTACTTTAAAATTAATGCGGGTAGATAAGCCGGTAGCTTATTTGCTGGTTTTTTTCCCTGC
TTTATTTGGATTGCTGCTTGCAAACCCTTCTAACACGGAATTAGCTTATTTATTACCGTTATTTATTTTAGGGAGTATAA
CGACAAGGAGTAGCGGGTGTATTATTAACGATATATTTGATAGAAAATTTGATAAACATGTTACACGGACTAAAGACCGA
CCTTTAGCAAGCGGTGCTTTATCTGTTTCTTATGCTATTTTTATACTTTTTATTCTTAGTATTATCTCGCTTTGTATATT
GCTACTTTTAAACAAAACAGCCATATATACAGGTTTTTTTGCGGTAATAATGATTAGCCTATATCCGCTAACGAAACGTA
TTACCTACTTTCCGCAAATATTTATGGGATTTACCTTTAATCTAGGGGCATTAATAGCGTATGCGGCAGTTCAGGATAAA
CTTGATTTAGCAGCAATTATTATATATTTAGCATGCTGTTTTTGGGCAACCGGTTATGATACGATTTACGGCTATATGGA
TATAAAAGACGATAAGAAAATAGGAGTGAAATCTTTAAGCATATATTTAGAAAACAAGCATCCTAAATTTTGGCTTGATG
TATGCTATATAGTTTTTATATTACTATTTACCCTAGCAACAAAGATAGCTAACCGTAATATCGACTATTTACCTATTTTA
GCTGCTTTAATTTTACTGATATTGCAAGTAGCGACGCTTGATATAAAAAATCCTGATTATTGTATGACAAGGTTCAGAGC
TAATAATTATGTCGGGGTACTTTTGAGTATGGTGTTTTATTAA

Upstream 100 bases:

>100_bases
TCTTATAATTTGCAGTAAAAAAGAATTTAATTAGTTTTACAATATCTTTACAGATAAGGTCTTAAAACAGAACGTGCCAA
AGAATTAATAAACAATAGAA

Downstream 100 bases:

>100_bases
ATTCTTGTACTAACAACAGTCTTATTAGGGATTAGATAATGTGCTTGATGTCATTCATGCGCAAGCAGACGAGTGTCAAC
TTAATAGCAACCTTACCGGA

Product: 4-hydroxybenzoate polyprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 280; Mature: 279

Protein sequence:

>280_residues
MPNKLLLTLKLMRVDKPVAYLLVFFPALFGLLLANPSNTELAYLLPLFILGSITTRSSGCIINDIFDRKFDKHVTRTKDR
PLASGALSVSYAIFILFILSIISLCILLLLNKTAIYTGFFAVIMISLYPLTKRITYFPQIFMGFTFNLGALIAYAAVQDK
LDLAAIIIYLACCFWATGYDTIYGYMDIKDDKKIGVKSLSIYLENKHPKFWLDVCYIVFILLFTLATKIANRNIDYLPIL
AALILLILQVATLDIKNPDYCMTRFRANNYVGVLLSMVFY

Sequences:

>Translated_280_residues
MPNKLLLTLKLMRVDKPVAYLLVFFPALFGLLLANPSNTELAYLLPLFILGSITTRSSGCIINDIFDRKFDKHVTRTKDR
PLASGALSVSYAIFILFILSIISLCILLLLNKTAIYTGFFAVIMISLYPLTKRITYFPQIFMGFTFNLGALIAYAAVQDK
LDLAAIIIYLACCFWATGYDTIYGYMDIKDDKKIGVKSLSIYLENKHPKFWLDVCYIVFILLFTLATKIANRNIDYLPIL
AALILLILQVATLDIKNPDYCMTRFRANNYVGVLLSMVFY
>Mature_279_residues
PNKLLLTLKLMRVDKPVAYLLVFFPALFGLLLANPSNTELAYLLPLFILGSITTRSSGCIINDIFDRKFDKHVTRTKDRP
LASGALSVSYAIFILFILSIISLCILLLLNKTAIYTGFFAVIMISLYPLTKRITYFPQIFMGFTFNLGALIAYAAVQDKL
DLAAIIIYLACCFWATGYDTIYGYMDIKDDKKIGVKSLSIYLENKHPKFWLDVCYIVFILLFTLATKIANRNIDYLPILA
ALILLILQVATLDIKNPDYCMTRFRANNYVGVLLSMVFY

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=278, Percent_Identity=35.2517985611511, Blast_Score=171, Evalue=5e-43,
Organism=Escherichia coli, GI1790473, Length=274, Percent_Identity=36.1313868613139, Blast_Score=170, Evalue=1e-43,
Organism=Caenorhabditis elegans, GI17553718, Length=277, Percent_Identity=38.9891696750903, Blast_Score=175, Evalue=3e-44,
Organism=Caenorhabditis elegans, GI32565247, Length=277, Percent_Identity=37.9061371841155, Blast_Score=160, Evalue=5e-40,
Organism=Caenorhabditis elegans, GI17553720, Length=334, Percent_Identity=30.8383233532934, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI32565245, Length=143, Percent_Identity=43.3566433566434, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI32565243, Length=152, Percent_Identity=42.1052631578947, Blast_Score=105, Evalue=3e-23,
Organism=Saccharomyces cerevisiae, GI6324370, Length=282, Percent_Identity=30.4964539007092, Blast_Score=134, Evalue=1e-32,
Organism=Drosophila melanogaster, GI21355567, Length=269, Percent_Identity=34.9442379182156, Blast_Score=165, Evalue=3e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 31752; Mature: 31620

Theoretical pI: Translated: 9.32; Mature: 9.32

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNKLLLTLKLMRVDKPVAYLLVFFPALFGLLLANPSNTELAYLLPLFILGSITTRSSGC
CCCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
IINDIFDRKFDKHVTRTKDRPLASGALSVSYAIFILFILSIISLCILLLLNKTAIYTGFF
EEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVIMISLYPLTKRITYFPQIFMGFTFNLGALIAYAAVQDKLDLAAIIIYLACCFWATGYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TIYGYMDIKDDKKIGVKSLSIYLENKHPKFWLDVCYIVFILLFTLATKIANRNIDYLPIL
HHEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AALILLILQVATLDIKNPDYCMTRFRANNYVGVLLSMVFY
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHC
>Mature Secondary Structure 
PNKLLLTLKLMRVDKPVAYLLVFFPALFGLLLANPSNTELAYLLPLFILGSITTRSSGC
CCCEEEEEHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCC
IINDIFDRKFDKHVTRTKDRPLASGALSVSYAIFILFILSIISLCILLLLNKTAIYTGFF
EEHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AVIMISLYPLTKRITYFPQIFMGFTFNLGALIAYAAVQDKLDLAAIIIYLACCFWATGYD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
TIYGYMDIKDDKKIGVKSLSIYLENKHPKFWLDVCYIVFILLFTLATKIANRNIDYLPIL
HHEEEEEECCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHH
AALILLILQVATLDIKNPDYCMTRFRANNYVGVLLSMVFY
HHHHHHHHHHHHHCCCCCHHHHHHHHCCCHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA