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The map label for this gene is ileS

Identifier: 157826014

GI number: 157826014

Start: 870809

End: 874120

Strand: Direct

Name: ileS

Synonym: A1C_04840

Alternate gene names: 157826014

Gene position: 870809-874120 (Clockwise)

Preceding gene: 157826012

Following gene: 157826015

Centisome position: 70.74

GC content: 37.68

Gene sequence:

>3312_bases
ATGGCCAATACTAAATATTATCCTGAAGTTAGTTCAAATGCTAATTTTGCTGCTATAGAGCGAGAGATACTAAAATTTTG
GCAAGACAATAATATATTTCAAAAATCTATTGATGGTAGGAATGGAGAATCAGAATTTATTTTTTATGACGGTCCACCTT
TTGCAAACGGTTTGCCGCATTATGGTCATTTACTTACCGGCTTTATTAAAGACGTATATGCTAGATACCAAACCGTAAAA
GGTAAGAAAGTTGAGCGTCGTTTCGGCTGGGATTGTCACGGTCTTCCTGCTGAAATGCAATCAGAGAAAGAGCTTGGTAT
TTCAGGGCGTCTTGCAATAACTAATTTCGGTATCGAGAAGTTTAATGCACATTGCAGAGCTTCAGTAATGGAATATGCGA
GCGACTGGGAAGAATATGTAACTCGTCAAGCAAGATGGGTAGATTTTAAAAATTCTTATAAAACGATGGATAAGAATTTT
ATGGAGTCCGTCCTTTGGGCGTTTAAAGAGCTGTATAATAAGGGGTTATTGTGTGAGTCTATGCGGGTAGTACCGTATTC
TTGGGCATGCGAAACACCGCTTTCTAATTTTGAAACAAGGCTTGATAATTCTTATCGTGAGCGATCAGATAAAGCTGTAA
CGGTGAGTTTCGTACTAAGGGATAAATTGCATGAGATTCCTGCTTTTGCAGGAATGATATCGAGGGAGTCAGAAATGACA
GTAGGCGGTGATTATCAAGAATATAGAATCCTTACTTGGACGACGACGCCTTGGACTCTTCCATCAAATCTAGCCATAGC
GGTCGGTAGTGATATAGATTATGCGTTAGTCCCTCAAGAAAATATTTGTTACATAATAGCTGCCTCGTCAGTTTCTAAAT
ATGCTAAAGAATTAGGGCTTAGCGGTGAAGAAAATTTTGAGATAATTAAAGGCTCACAGCTTCAGGGACTCCGCTATAAA
CCTTTATTCGACTATTTTGAGCATCATCCAAACAGCTTCAAGATATTTGACGTCGACTTTGTTGTTGAAGGTGACGGTAC
AGGGGTTGTACATATGGCTCCCGGCTTTGGTGAAGATGACCAAATACTTTGCGAATCAAAAGGGATCTCACTTGTTTGTC
CTGTGGATAATAGCGGTAAATTTACTAAAGAAATTCCTGATTTAGAGGGAGTGCAAGTATTTGATGCAAATGACAAAATA
ATAATCAAACTGAAAGAGCAAGGAAATTGGCTAAAAACCGAGCAGTATATTCATAATTATCCTCATTGCTGGCGGACGGA
TACGCCTCTTATATATAAGGCTGTTCCGTCATGGTATGTCAAGGTAACGCAGTTTAAAGATAGGATGGTAGAGCTTAATC
AGCAAATAAACTGGATCCCACATCATGTTAAAGATAATTTATTCGGTAAGTGGCTTGAAAATGCACGTGATTGGTCGATA
AGCCGTAATAGATTTTGGGGAACGCCGCTTCCTGTATGGAAATCAGACGATCCAAAATATCCACGCATAGATGTTTACGG
CTCTATAGAGGAATTAGAGAAAGATTTCGGCGTTAAAGTTACTGATTTACATCGTCCATTTATCGATAAACTGACAAGAC
CAAACCCAAACGATCCAACCGGTAAATCAACAATGCGTAGAATCGAAGACGTGTTTGATTGCTGGTTTGAAAGCGGCTCG
ATGCCATATGGGCAAGCTCACTACCCTTTTGAAAATAAAGAGTGGTTCGAGGATCATTTTCCGGCTGATTTTATAGTTGA
GTATTCAGCTCAAACACGTGGTTGGTTTTATACTTTAATGGTGCTATCTACCGCTTTATTTGATCGTCCACCGTTTTTAA
ATTGTATATGCCACGGTGTAATTTTAGACGCTACCGGCCAAAAACTCTCAAAGCGCCTTAATAACTACGCCGATCCGCTG
GAGCTATTTGATCAATACGGCTCTGACGCATTAAGAGTTACGATGCTATCTTCAAACATTGTTAAAGGTCAGGAACTGCT
AATCGATAAAGACGGTAAGATGGTATTTGATACGCTTCGTCTATTCATCAAGCCTATATGGAGTTCTTATCATTTCTTTA
CGATGTATGCTAATGCCGATTCGCTTAAAGGTGAGATTAGTTTTGCTTCTGAAAACGTACTTGATGTTTATATATTATCT
AAGCTAAAAATAGCAGTCAGTAAGATTGAAGAGAGTTTGGATAATTTCGATACGCAAACAGCTTATCATGCAGTTTTAGA
ATTTTTTGAAGTATTGAATAACTGGTATATAAGACGAAGTAGAGCAAGATTTTGGAAAAGCGAAAAAGATACAGATAAAC
AAAATGCTTATAATACTCTATATTCATGTTTAAAGACTATGGCAATTGCAATGTCTGCACTAGTGCCTATGATTTCGGAG
GCGATATATAAGGGGCTATGTCATTGCGAAGAGACGTCTACATTGTCATCCCGCGACTTGATCGCAGGATCCAGTAAATC
GATAAACAATTTGAATCCAGTGGTCAAGCCACGGGATTACACCCCATCAGTGCATCACAATGACCAAATTAGCGTCCATC
TATGCAACTACCCCACTCTCTCAGACTTTGAAATAAATCACGAGCTAGTTGCTACTATGGATAACGTGCTTGATATTTGT
AGTAATAGCCTGTTTATTAGAAGTACTAAAAATATCAGGGTAAGGCAGCCGCTGGCTAGCATAACTATTATCAGCAAACA
TAATAATGATCTAAAAGCTTTTGAAAATTTGATCAAGGATGAGATTAATGTGAAATCAGTAATTTATTGCGACGATCTAG
AGAATTACGCAAGCAAAAAACTATCGATTAATTTCCCAATGCTTGGTAAACGTCTTCCAGCTAAAATGAAAGAGATTATA
GCTGCTTCTAAAAAAGGTGACTGGAAAGCTATCGCAGGCGGTTTAACTATATGCGGTGAAACCTTAAATAATGAGGAATA
TAAGCTAATTTTGGAGCCATATTCACATATAAAAGGAGCAGCAAGTTTTGAGAATAATAGCAGCTTGTTAATACTTGATT
TAGAGCTAACAGCTGAGCTAATAGAAGAAGGATACGCAAGAGATATTGTACGCTTCATACAACAGGCTCGAAAAGATGCA
GGTTTCTCTATAACTGACAGGATTTTAATTGAGATAATAAGCGAGTTTGATTTATCTGAGATAATTTATAATTATGGAGA
CTTTATTACAGAACAAACTTTAGGCGAGTTTTCTAAAAATTTTACGCCTGATTATGTAAGTAAAGTAGAATTAGAGGATC
ATCCAATACAACTTAAGATTAAGAAATCGTAA

Upstream 100 bases:

>100_bases
GTCCGTTAGAAGTAATAGCTAAAAGTAATATATTAAAATTCTTGTGTTATTACCTCTCTTGTATATAATTAGGATGTTTT
TAAAAATAATTTCTAAAATG

Downstream 100 bases:

>100_bases
ATTATTTTACTATTGATTAAGGTATTAATAATTTACTTATATTAATCTATAGTATGCACGCTATAAATTAATTTAGGTAA
ATTATGTCACAATACTCCTC

Product: isoleucyl-tRNA synthetase

Products: NA

Alternate protein names: Isoleucine--tRNA ligase; IleRS

Number of amino acids: Translated: 1103; Mature: 1102

Protein sequence:

>1103_residues
MANTKYYPEVSSNANFAAIEREILKFWQDNNIFQKSIDGRNGESEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTVK
GKKVERRFGWDCHGLPAEMQSEKELGISGRLAITNFGIEKFNAHCRASVMEYASDWEEYVTRQARWVDFKNSYKTMDKNF
MESVLWAFKELYNKGLLCESMRVVPYSWACETPLSNFETRLDNSYRERSDKAVTVSFVLRDKLHEIPAFAGMISRESEMT
VGGDYQEYRILTWTTTPWTLPSNLAIAVGSDIDYALVPQENICYIIAASSVSKYAKELGLSGEENFEIIKGSQLQGLRYK
PLFDYFEHHPNSFKIFDVDFVVEGDGTGVVHMAPGFGEDDQILCESKGISLVCPVDNSGKFTKEIPDLEGVQVFDANDKI
IIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPHHVKDNLFGKWLENARDWSI
SRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDKLTRPNPNDPTGKSTMRRIEDVFDCWFESGS
MPYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPL
ELFDQYGSDALRVTMLSSNIVKGQELLIDKDGKMVFDTLRLFIKPIWSSYHFFTMYANADSLKGEISFASENVLDVYILS
KLKIAVSKIEESLDNFDTQTAYHAVLEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLKTMAIAMSALVPMISE
AIYKGLCHCEETSTLSSRDLIAGSSKSINNLNPVVKPRDYTPSVHHNDQISVHLCNYPTLSDFEINHELVATMDNVLDIC
SNSLFIRSTKNIRVRQPLASITIISKHNNDLKAFENLIKDEINVKSVIYCDDLENYASKKLSINFPMLGKRLPAKMKEII
AASKKGDWKAIAGGLTICGETLNNEEYKLILEPYSHIKGAASFENNSSLLILDLELTAELIEEGYARDIVRFIQQARKDA
GFSITDRILIEIISEFDLSEIIYNYGDFITEQTLGEFSKNFTPDYVSKVELEDHPIQLKIKKS

Sequences:

>Translated_1103_residues
MANTKYYPEVSSNANFAAIEREILKFWQDNNIFQKSIDGRNGESEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTVK
GKKVERRFGWDCHGLPAEMQSEKELGISGRLAITNFGIEKFNAHCRASVMEYASDWEEYVTRQARWVDFKNSYKTMDKNF
MESVLWAFKELYNKGLLCESMRVVPYSWACETPLSNFETRLDNSYRERSDKAVTVSFVLRDKLHEIPAFAGMISRESEMT
VGGDYQEYRILTWTTTPWTLPSNLAIAVGSDIDYALVPQENICYIIAASSVSKYAKELGLSGEENFEIIKGSQLQGLRYK
PLFDYFEHHPNSFKIFDVDFVVEGDGTGVVHMAPGFGEDDQILCESKGISLVCPVDNSGKFTKEIPDLEGVQVFDANDKI
IIKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPHHVKDNLFGKWLENARDWSI
SRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDKLTRPNPNDPTGKSTMRRIEDVFDCWFESGS
MPYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPL
ELFDQYGSDALRVTMLSSNIVKGQELLIDKDGKMVFDTLRLFIKPIWSSYHFFTMYANADSLKGEISFASENVLDVYILS
KLKIAVSKIEESLDNFDTQTAYHAVLEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLKTMAIAMSALVPMISE
AIYKGLCHCEETSTLSSRDLIAGSSKSINNLNPVVKPRDYTPSVHHNDQISVHLCNYPTLSDFEINHELVATMDNVLDIC
SNSLFIRSTKNIRVRQPLASITIISKHNNDLKAFENLIKDEINVKSVIYCDDLENYASKKLSINFPMLGKRLPAKMKEII
AASKKGDWKAIAGGLTICGETLNNEEYKLILEPYSHIKGAASFENNSSLLILDLELTAELIEEGYARDIVRFIQQARKDA
GFSITDRILIEIISEFDLSEIIYNYGDFITEQTLGEFSKNFTPDYVSKVELEDHPIQLKIKKS
>Mature_1102_residues
ANTKYYPEVSSNANFAAIEREILKFWQDNNIFQKSIDGRNGESEFIFYDGPPFANGLPHYGHLLTGFIKDVYARYQTVKG
KKVERRFGWDCHGLPAEMQSEKELGISGRLAITNFGIEKFNAHCRASVMEYASDWEEYVTRQARWVDFKNSYKTMDKNFM
ESVLWAFKELYNKGLLCESMRVVPYSWACETPLSNFETRLDNSYRERSDKAVTVSFVLRDKLHEIPAFAGMISRESEMTV
GGDYQEYRILTWTTTPWTLPSNLAIAVGSDIDYALVPQENICYIIAASSVSKYAKELGLSGEENFEIIKGSQLQGLRYKP
LFDYFEHHPNSFKIFDVDFVVEGDGTGVVHMAPGFGEDDQILCESKGISLVCPVDNSGKFTKEIPDLEGVQVFDANDKII
IKLKEQGNWLKTEQYIHNYPHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPHHVKDNLFGKWLENARDWSIS
RNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDKLTRPNPNDPTGKSTMRRIEDVFDCWFESGSM
PYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLMVLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPLE
LFDQYGSDALRVTMLSSNIVKGQELLIDKDGKMVFDTLRLFIKPIWSSYHFFTMYANADSLKGEISFASENVLDVYILSK
LKIAVSKIEESLDNFDTQTAYHAVLEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTLYSCLKTMAIAMSALVPMISEA
IYKGLCHCEETSTLSSRDLIAGSSKSINNLNPVVKPRDYTPSVHHNDQISVHLCNYPTLSDFEINHELVATMDNVLDICS
NSLFIRSTKNIRVRQPLASITIISKHNNDLKAFENLIKDEINVKSVIYCDDLENYASKKLSINFPMLGKRLPAKMKEIIA
ASKKGDWKAIAGGLTICGETLNNEEYKLILEPYSHIKGAASFENNSSLLILDLELTAELIEEGYARDIVRFIQQARKDAG
FSITDRILIEIISEFDLSEIIYNYGDFITEQTLGEFSKNFTPDYVSKVELEDHPIQLKIKKS

Specific function: Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activi

COG id: COG0060

COG function: function code J; Isoleucyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily

Homologues:

Organism=Homo sapiens, GI94721239, Length=1094, Percent_Identity=38.2998171846435, Blast_Score=753, Evalue=0.0,
Organism=Homo sapiens, GI94721241, Length=1094, Percent_Identity=38.2998171846435, Blast_Score=753, Evalue=0.0,
Organism=Homo sapiens, GI46852147, Length=812, Percent_Identity=27.4630541871921, Blast_Score=272, Evalue=2e-72,
Organism=Homo sapiens, GI5454158, Length=869, Percent_Identity=21.5189873417722, Blast_Score=145, Evalue=2e-34,
Organism=Homo sapiens, GI268370293, Length=829, Percent_Identity=22.3160434258142, Blast_Score=135, Evalue=2e-31,
Organism=Homo sapiens, GI268370295, Length=810, Percent_Identity=22.3456790123457, Blast_Score=135, Evalue=3e-31,
Organism=Homo sapiens, GI268370297, Length=829, Percent_Identity=22.3160434258142, Blast_Score=135, Evalue=3e-31,
Organism=Escherichia coli, GI2367096, Length=802, Percent_Identity=27.431421446384, Blast_Score=312, Evalue=6e-86,
Organism=Escherichia coli, GI1790708, Length=854, Percent_Identity=20.8430913348946, Blast_Score=126, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI17541896, Length=1074, Percent_Identity=38.5474860335196, Blast_Score=733, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71980946, Length=821, Percent_Identity=26.1875761266748, Blast_Score=229, Evalue=5e-60,
Organism=Caenorhabditis elegans, GI17510661, Length=851, Percent_Identity=21.7391304347826, Blast_Score=158, Evalue=1e-38,
Organism=Caenorhabditis elegans, GI72001587, Length=826, Percent_Identity=23.8498789346247, Blast_Score=150, Evalue=3e-36,
Organism=Saccharomyces cerevisiae, GI6319395, Length=1114, Percent_Identity=36.8940754039497, Blast_Score=716, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6325217, Length=694, Percent_Identity=29.6829971181556, Blast_Score=246, Evalue=2e-65,
Organism=Saccharomyces cerevisiae, GI6321531, Length=843, Percent_Identity=23.6061684460261, Blast_Score=183, Evalue=1e-46,
Organism=Drosophila melanogaster, GI28574730, Length=1153, Percent_Identity=36.6001734605377, Blast_Score=706, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668547, Length=1153, Percent_Identity=36.6001734605377, Blast_Score=706, Evalue=0.0,
Organism=Drosophila melanogaster, GI24668543, Length=1153, Percent_Identity=36.6001734605377, Blast_Score=706, Evalue=0.0,
Organism=Drosophila melanogaster, GI281366294, Length=810, Percent_Identity=25.8024691358025, Blast_Score=228, Evalue=1e-59,
Organism=Drosophila melanogaster, GI17864482, Length=858, Percent_Identity=22.3776223776224, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI24653289, Length=858, Percent_Identity=22.3776223776224, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI21355675, Length=812, Percent_Identity=22.5369458128079, Blast_Score=141, Evalue=2e-33,

Paralogues:

None

Copy number: 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SYI_RICAH (A8GPA1)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493734.1
- ProteinModelPortal:   A8GPA1
- STRING:   A8GPA1
- GeneID:   5645801
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_04840
- NMPDR:   fig|293614.3.peg.904
- eggNOG:   COG0060
- HOGENOM:   HBG577712
- OMA:   DCHGLPA
- ProtClustDB:   PRK06039
- BioCyc:   RAKA293614:A1C_04840-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_02003
- InterPro:   IPR001412
- InterPro:   IPR002300
- InterPro:   IPR002301
- InterPro:   IPR014729
- InterPro:   IPR022439
- InterPro:   IPR009080
- InterPro:   IPR013155
- InterPro:   IPR009008
- Gene3D:   G3DSA:3.40.50.620
- PANTHER:   PTHR11946:SF9
- PRINTS:   PR00984
- TIGRFAMs:   TIGR00392
- TIGRFAMs:   TIGR03777

Pfam domain/function: PF08264 Anticodon_1; PF00133 tRNA-synt_1; SSF47323 tRNAsyn_1a_bind; SSF50677 ValRS_IleRS_edit

EC number: =6.1.1.5

Molecular weight: Translated: 126772; Mature: 126641

Theoretical pI: Translated: 5.47; Mature: 5.47

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: BINDING 631-631

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MANTKYYPEVSSNANFAAIEREILKFWQDNNIFQKSIDGRNGESEFIFYDGPPFANGLPH
CCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEECCCCCCCCCCH
YGHLLTGFIKDVYARYQTVKGKKVERRFGWDCHGLPAEMQSEKELGISGRLAITNFGIEK
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEEECCHHH
FNAHCRASVMEYASDWEEYVTRQARWVDFKNSYKTMDKNFMESVLWAFKELYNKGLLCES
HHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
MRVVPYSWACETPLSNFETRLDNSYRERSDKAVTVSFVLRDKLHEIPAFAGMISRESEMT
CEECEECCCCCCCHHHHHHHHCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCE
VGGDYQEYRILTWTTTPWTLPSNLAIAVGSDIDYALVPQENICYIIAASSVSKYAKELGL
ECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCEEEECCCCEEEEEECHHHHHHHHHHCC
SGEENFEIIKGSQLQGLRYKPLFDYFEHHPNSFKIFDVDFVVEGDGTGVVHMAPGFGEDD
CCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEECCCCCCCC
QILCESKGISLVCPVDNSGKFTKEIPDLEGVQVFDANDKIIIKLKEQGNWLKTEQYIHNY
CEEEECCCCEEEEECCCCCCCHHCCCCCCCEEEEECCCEEEEEECCCCCEEHHHHHHHCC
PHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPHHVKDNLFGKWLENARDWSI
CCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
SRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDKLTRPNPNDPT
CCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCEEECCCCHHHHHHCCCCCCCCC
GKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLM
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCHHHHHH
VLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPLELFDQYGSDALRVTMLSSNI
HHHHHHHCCCCHHHHHHHCEEEECCCHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCC
VKGQELLIDKDGKMVFDTLRLFIKPIWSSYHFFTMYANADSLKGEISFASENVLDVYILS
CCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEEECCCCCEEHHHHH
KLKIAVSKIEESLDNFDTQTAYHAVLEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
YSCLKTMAIAMSALVPMISEAIYKGLCHCEETSTLSSRDLIAGSSKSINNLNPVVKPRDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCC
TPSVHHNDQISVHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTKNIRVRQPLAS
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCEE
ITIISKHNNDLKAFENLIKDEINVKSVIYCDDLENYASKKLSINFPMLGKRLPAKMKEII
EEEEECCCCHHHHHHHHHHCCCCCEEEEEECCHHHHCCCEEEECCCCCCCCCCHHHHHHH
AASKKGDWKAIAGGLTICGETLNNEEYKLILEPYSHIKGAASFENNSSLLILDLELTAEL
HHCCCCCCHHHHCCHHEECCCCCCCCEEEEECCHHHCCCCCCCCCCCCEEEEEHHHHHHH
IEEGYARDIVRFIQQARKDAGFSITDRILIEIISEFDLSEIIYNYGDFITEQTLGEFSKN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
FTPDYVSKVELEDHPIQLKIKKS
CCCHHHHEEEECCCCEEEEEECC
>Mature Secondary Structure 
ANTKYYPEVSSNANFAAIEREILKFWQDNNIFQKSIDGRNGESEFIFYDGPPFANGLPH
CCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHCCCCCCCCCEEEECCCCCCCCCCH
YGHLLTGFIKDVYARYQTVKGKKVERRFGWDCHGLPAEMQSEKELGISGRLAITNFGIEK
HHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCHHHCCCCCCCCCCEEEEEECCHHH
FNAHCRASVMEYASDWEEYVTRQARWVDFKNSYKTMDKNFMESVLWAFKELYNKGLLCES
HHHHHHHHHHHHHHHHHHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECC
MRVVPYSWACETPLSNFETRLDNSYRERSDKAVTVSFVLRDKLHEIPAFAGMISRESEMT
CEECEECCCCCCCHHHHHHHHCCHHHHCCCCEEEEHHHHHHHHHHHHHHHHHHCCCCCCE
VGGDYQEYRILTWTTTPWTLPSNLAIAVGSDIDYALVPQENICYIIAASSVSKYAKELGL
ECCCCCCEEEEEEECCCCCCCCCEEEEECCCCCEEEECCCCEEEEEECHHHHHHHHHHCC
SGEENFEIIKGSQLQGLRYKPLFDYFEHHPNSFKIFDVDFVVEGDGTGVVHMAPGFGEDD
CCCCCCEEEECCCCCCCCCCHHHHHHHCCCCCEEEEEEEEEEECCCCEEEEECCCCCCCC
QILCESKGISLVCPVDNSGKFTKEIPDLEGVQVFDANDKIIIKLKEQGNWLKTEQYIHNY
CEEEECCCCEEEEECCCCCCCHHCCCCCCCEEEEECCCEEEEEECCCCCEEHHHHHHHCC
PHCWRTDTPLIYKAVPSWYVKVTQFKDRMVELNQQINWIPHHVKDNLFGKWLENARDWSI
CCCCCCCCCEEEEECCCCEEEHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCC
SRNRFWGTPLPVWKSDDPKYPRIDVYGSIEELEKDFGVKVTDLHRPFIDKLTRPNPNDPT
CCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCEEECCCCHHHHHHCCCCCCCCC
GKSTMRRIEDVFDCWFESGSMPYGQAHYPFENKEWFEDHFPADFIVEYSAQTRGWFYTLM
CHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHCCCCEEEEEECCCCCCHHHHHH
VLSTALFDRPPFLNCICHGVILDATGQKLSKRLNNYADPLELFDQYGSDALRVTMLSSNI
HHHHHHHCCCCHHHHHHHCEEEECCCHHHHHHHHCCCCHHHHHHHHCCCEEEEEEECCCC
VKGQELLIDKDGKMVFDTLRLFIKPIWSSYHFFTMYANADSLKGEISFASENVLDVYILS
CCCCEEEEECCCCHHHHHHHHHHHHHHCCEEEEEEEECCCCCCCEEEECCCCCEEHHHHH
KLKIAVSKIEESLDNFDTQTAYHAVLEFFEVLNNWYIRRSRARFWKSEKDTDKQNAYNTL
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHH
YSCLKTMAIAMSALVPMISEAIYKGLCHCEETSTLSSRDLIAGSSKSINNLNPVVKPRDY
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEECCCCCCCCCCCCCCCCCCC
TPSVHHNDQISVHLCNYPTLSDFEINHELVATMDNVLDICSNSLFIRSTKNIRVRQPLAS
CCCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCEEEECCCEE
ITIISKHNNDLKAFENLIKDEINVKSVIYCDDLENYASKKLSINFPMLGKRLPAKMKEII
EEEEECCCCHHHHHHHHHHCCCCCEEEEEECCHHHHCCCEEEECCCCCCCCCCHHHHHHH
AASKKGDWKAIAGGLTICGETLNNEEYKLILEPYSHIKGAASFENNSSLLILDLELTAEL
HHCCCCCCHHHHCCHHEECCCCCCCCEEEEECCHHHCCCCCCCCCCCCEEEEEHHHHHHH
IEEGYARDIVRFIQQARKDAGFSITDRILIEIISEFDLSEIIYNYGDFITEQTLGEFSKN
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCC
FTPDYVSKVELEDHPIQLKIKKS
CCCHHHHEEEECCCCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA