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The map label for this gene is exoC [H]

Identifier: 157825776

GI number: 157825776

Start: 636513

End: 637955

Strand: Reverse

Name: exoC [H]

Synonym: A1C_03535

Alternate gene names: 157825776

Gene position: 637955-636513 (Counterclockwise)

Preceding gene: 157825777

Following gene: 157825775

Centisome position: 51.82

GC content: 34.79

Gene sequence:

>1443_bases
ATGCAAATTAACAAAGAAATTTTTAGAGCTTATGATATAAGAGGCAATAGCCTTAAGGATTTAACAGAAGAAATAGCTTA
TAAAATCGGCTTTTGTTTCGCCAAGATGACTATCACAAAAGATAATAGCAAAATCTGTATTGGTTTAGACGGTCGGCTCA
GCTCCCATACCCTTTGTAAAGCTTTAGAATTAGGACTAACTGATGCAGGGGCTGAAATCATAAATATTGGCGTAGTTCCG
ACACCAGTACTATATTTTGTCGATAAACAATTTATGCCTGCCGGTAGTATTATGGTTACGGGATCGCATAATCCTCGTGA
CGATAACGGCTTTAAAATGCTGCAACACGGTAAATCTTTTTTCGGTGATCAGATAAAGGATTTATTAGCAAAGGTTTTGA
ATAATCATGTTATGCCCACAACCCCTGATGTCATTCCTGCGAAAGCAGGAATTCATATTAATACAAGTGGAGACATGGAT
TTCCGATTTCGCGGGCATGACATATATTGTGGACATAATATAGAACATAAATACCTAAAACGTATTTTAGAGGGAATAAA
TATTAATCCGCAGTTAAAAGTGTCTTGGGACTGCAGCAATGGAGCAACAGGCAATATTATTGAAGAGTTAAAAAAGCATT
TAACTAATCACAACATAATCATAAATAGTAGGATTGACGGGAATTTTCCAAGCCATCACCCTGACCCTACCAACCCTGCT
AATTTACAAGAGCTAATAAAAGTGGTTAAAGAACAAAATTGTGACCTTGGTATAGCTTTTGACGGTGACGGTGATAGAAT
CGGTATTGTAAGCGGGGGCGGTAAGATATTATTCGGTGATCAAATTTTATGTATATTTGCTGAGAATATTTTAAAGGAAC
ATCCGAGTGTTACCATAATAGTCGATGTAAAAGCCAGTCAGTTAATAGTTGATAGAATTAGGTCATTTGGCGGAAATCCT
ATAATATGGCGAACAGGTCATCCTTTTATTAAAAGCAAAATGCTTGAAACAAATGCTTTACTCGCCGGTGAAATGAGCGG
GCATATATTCTTTGCCGATAAATATTTTGGCTTTGATGATGCAATTTATGCAGCACTTAGATTTTTAGATTTACTTAGCA
AATCAAGTAAGACTCTGGATGAAATAATAGAGGATTTACCGAAAAGCTATAGTACACCGGAAATTAAAATATTTGTTCCG
TCTAGGTTAAAATTACAAATTATTAAAGAGATTAAAGAAAAATTATTAGAAGAGAAAATAGAGTTTAATGATATAGACGG
TGTACGGGTAAATACCGAGCATGGTTGGTGGTTACTGCGTAGTTCTAACACCGAATCTATTATAGTTGCAAGAGCTGAAT
CAGCTAGTAAAAATGGCTTAGGGAAAATAATAGCTATAATTAATAAATATCTTGAAAAATACGGGCTATTAATTAATTAT
TAA

Upstream 100 bases:

>100_bases
GATCCAGTAAAACATATAAAAACAAGTTTTTATATGTTTATAATTATTAATGTTATTTTTTAGATGCCAGCTCTCGCGGG
CATGACATAAATGGTTTTTT

Downstream 100 bases:

>100_bases
AGAATTATTGCTTTCTAAAATATTATTTTATATATTTTTCTCACACGTAACGACCTTGCGCCTACTAATTATGATTCTCT
TGTTTTTAAACTTAAAGATG

Product: phosphomannomutase

Products: NA

Alternate protein names: PMM [H]

Number of amino acids: Translated: 480; Mature: 480

Protein sequence:

>480_residues
MQINKEIFRAYDIRGNSLKDLTEEIAYKIGFCFAKMTITKDNSKICIGLDGRLSSHTLCKALELGLTDAGAEIINIGVVP
TPVLYFVDKQFMPAGSIMVTGSHNPRDDNGFKMLQHGKSFFGDQIKDLLAKVLNNHVMPTTPDVIPAKAGIHINTSGDMD
FRFRGHDIYCGHNIEHKYLKRILEGININPQLKVSWDCSNGATGNIIEELKKHLTNHNIIINSRIDGNFPSHHPDPTNPA
NLQELIKVVKEQNCDLGIAFDGDGDRIGIVSGGGKILFGDQILCIFAENILKEHPSVTIIVDVKASQLIVDRIRSFGGNP
IIWRTGHPFIKSKMLETNALLAGEMSGHIFFADKYFGFDDAIYAALRFLDLLSKSSKTLDEIIEDLPKSYSTPEIKIFVP
SRLKLQIIKEIKEKLLEEKIEFNDIDGVRVNTEHGWWLLRSSNTESIIVARAESASKNGLGKIIAIINKYLEKYGLLINY

Sequences:

>Translated_480_residues
MQINKEIFRAYDIRGNSLKDLTEEIAYKIGFCFAKMTITKDNSKICIGLDGRLSSHTLCKALELGLTDAGAEIINIGVVP
TPVLYFVDKQFMPAGSIMVTGSHNPRDDNGFKMLQHGKSFFGDQIKDLLAKVLNNHVMPTTPDVIPAKAGIHINTSGDMD
FRFRGHDIYCGHNIEHKYLKRILEGININPQLKVSWDCSNGATGNIIEELKKHLTNHNIIINSRIDGNFPSHHPDPTNPA
NLQELIKVVKEQNCDLGIAFDGDGDRIGIVSGGGKILFGDQILCIFAENILKEHPSVTIIVDVKASQLIVDRIRSFGGNP
IIWRTGHPFIKSKMLETNALLAGEMSGHIFFADKYFGFDDAIYAALRFLDLLSKSSKTLDEIIEDLPKSYSTPEIKIFVP
SRLKLQIIKEIKEKLLEEKIEFNDIDGVRVNTEHGWWLLRSSNTESIIVARAESASKNGLGKIIAIINKYLEKYGLLINY
>Mature_480_residues
MQINKEIFRAYDIRGNSLKDLTEEIAYKIGFCFAKMTITKDNSKICIGLDGRLSSHTLCKALELGLTDAGAEIINIGVVP
TPVLYFVDKQFMPAGSIMVTGSHNPRDDNGFKMLQHGKSFFGDQIKDLLAKVLNNHVMPTTPDVIPAKAGIHINTSGDMD
FRFRGHDIYCGHNIEHKYLKRILEGININPQLKVSWDCSNGATGNIIEELKKHLTNHNIIINSRIDGNFPSHHPDPTNPA
NLQELIKVVKEQNCDLGIAFDGDGDRIGIVSGGGKILFGDQILCIFAENILKEHPSVTIIVDVKASQLIVDRIRSFGGNP
IIWRTGHPFIKSKMLETNALLAGEMSGHIFFADKYFGFDDAIYAALRFLDLLSKSSKTLDEIIEDLPKSYSTPEIKIFVP
SRLKLQIIKEIKEKLLEEKIEFNDIDGVRVNTEHGWWLLRSSNTESIIVARAESASKNGLGKIIAIINKYLEKYGLLINY

Specific function: Involved In The Biosynthesis Of The Capsular Polysaccharide Colanic Acid. [C]

COG id: COG1109

COG function: function code G; Phosphomannomutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the phosphohexose mutase family [H]

Homologues:

Organism=Homo sapiens, GI290463102, Length=383, Percent_Identity=22.4543080939948, Blast_Score=69, Evalue=1e-11,
Organism=Homo sapiens, GI21361621, Length=383, Percent_Identity=22.976501305483, Blast_Score=67, Evalue=3e-11,
Organism=Escherichia coli, GI1788361, Length=460, Percent_Identity=30.8695652173913, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1789566, Length=447, Percent_Identity=27.0693512304251, Blast_Score=102, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005844
- InterPro:   IPR016055
- InterPro:   IPR005845
- InterPro:   IPR005846
- InterPro:   IPR005843
- InterPro:   IPR016066
- InterPro:   IPR005841 [H]

Pfam domain/function: PF02878 PGM_PMM_I; PF02879 PGM_PMM_II; PF02880 PGM_PMM_III; PF00408 PGM_PMM_IV [H]

EC number: =5.4.2.8 [H]

Molecular weight: Translated: 53617; Mature: 53617

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS00710 PGM_PMM

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQINKEIFRAYDIRGNSLKDLTEEIAYKIGFCFAKMTITKDNSKICIGLDGRLSSHTLCK
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEEEEEECCCEEEEEECCCCCHHHHHH
ALELGLTDAGAEIINIGVVPTPVLYFVDKQFMPAGSIMVTGSHNPRDDNGFKMLQHGKSF
HHHCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
FGDQIKDLLAKVLNNHVMPTTPDVIPAKAGIHINTSGDMDFRFRGHDIYCGHNIEHKYLK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCEEEECCCCCHHHHH
RILEGININPQLKVSWDCSNGATGNIIEELKKHLTNHNIIINSRIDGNFPSHHPDPTNPA
HHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
NLQELIKVVKEQNCDLGIAFDGDGDRIGIVSGGGKILFGDQILCIFAENILKEHPSVTII
CHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCEEEECCCEEEHHHHHHHHHCCCEEEE
VDVKASQLIVDRIRSFGGNPIIWRTGHPFIKSKMLETNALLAGEMSGHIFFADKYFGFDD
EECCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCEEEECCCCEEEEEECCCCCHH
AIYAALRFLDLLSKSSKTLDEIIEDLPKSYSTPEIKIFVPSRLKLQIIKEIKEKLLEEKI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHC
EFNDIDGVRVNTEHGWWLLRSSNTESIIVARAESASKNGLGKIIAIINKYLEKYGLLINY
CCCCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEECC
>Mature Secondary Structure
MQINKEIFRAYDIRGNSLKDLTEEIAYKIGFCFAKMTITKDNSKICIGLDGRLSSHTLCK
CCCCHHHHHHHCCCCCCHHHHHHHHHHHHHEEEEEEEEEECCCEEEEEECCCCCHHHHHH
ALELGLTDAGAEIINIGVVPTPVLYFVDKQFMPAGSIMVTGSHNPRDDNGFKMLQHGKSF
HHHCCCCCCCCEEEEECCCCCCCEEEECCCCCCCCCEEEECCCCCCCCCCHHHHHHHHHH
FGDQIKDLLAKVLNNHVMPTTPDVIPAKAGIHINTSGDMDFRFRGHDIYCGHNIEHKYLK
HHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEECCCCEEEEEECCEEEECCCCCHHHHH
RILEGININPQLKVSWDCSNGATGNIIEELKKHLTNHNIIINSRIDGNFPSHHPDPTNPA
HHHHCCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCCCCCCCCCC
NLQELIKVVKEQNCDLGIAFDGDGDRIGIVSGGGKILFGDQILCIFAENILKEHPSVTII
CHHHHHHHHHHCCCCEEEEECCCCCEEEEEECCCEEEECCCEEEHHHHHHHHHCCCEEEE
VDVKASQLIVDRIRSFGGNPIIWRTGHPFIKSKMLETNALLAGEMSGHIFFADKYFGFDD
EECCHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHHCCEEEECCCCEEEEEECCCCCHH
AIYAALRFLDLLSKSSKTLDEIIEDLPKSYSTPEIKIFVPSRLKLQIIKEIKEKLLEEKI
HHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHHHHHC
EFNDIDGVRVNTEHGWWLLRSSNTESIIVARAESASKNGLGKIIAIINKYLEKYGLLINY
CCCCCCCEEEECCCCEEEEECCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHHHCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA