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The map label for this gene is ctaA

Identifier: 157825472

GI number: 157825472

Start: 349210

End: 350166

Strand: Direct

Name: ctaA

Synonym: A1C_01865

Alternate gene names: 157825472

Gene position: 349210-350166 (Clockwise)

Preceding gene: 157825471

Following gene: 157825473

Centisome position: 28.37

GC content: 31.56

Gene sequence:

>957_bases
ATGGTTGTTATAGGGGGTATCACAAGGCTTACAGGTGCTGGTTTATCTATAGTTGAGTGGCGTCCTGTAACCGGTATTTT
GCCGCCTTTTAGCTTTGAAAGCTGGCAAGCGGAATTTGCGAAATATAAAGCTTTTCCTGAATATAACTCCGTTAATTACG
GAATGACTTTATCAGAGTTTAAGTGTATTTATCTGTTAGAGTTTATACATCGATTACTCGGTAGAATGACAGTGTTAATA
TATATTGTACCTTTAATATATTTTTATTTTAAAGATGTTATAAAAAATTGTGACATGCTACCTTATATAATTGCTTTGTT
GTTATTTTGTGTACAAGGTTTTATGGGGTGGTATATGGTTAAAAGCGGCTTGTTGAATAGCCCGTCTGTTAGTCATTTTC
GACTTGCTTTTCATTTAATTATCGCCGTAATTATTTATCACATACTTTTTTATCAATTAATAAAAAATCGTTGTGATATT
TTGTTAATCCCGTCACAAACAGATTTAAAATTACCACTAATATTTTCCGGTATTGCTATTACTGTAATATATGTGCAAAT
TTTTTTAGGGGCGCTGGTTGCAGGGCTTGATGCAGGGCTGATATATAATAGTTTTCCGCTAATGGGGGATCATTGTATCC
CGATGGAGATAAAAGATAATTTCTTTAATCTTGCAAATTTGCATGATCCAGTTTTTATACAATTTATACATCGTTTAGGC
AGCTATAGCGTATTTTTGGTTGTTGTTGTTTTAGTAATTTGCTTGTTAACAATAGAACATCCGAAATTAAATAAGATAGC
GTATTTTCTAATGATTGCATTATTGATGCAGATATCTACCGGAATAATTACTCTTTTATATTCTGTCCCTATAATCATTG
CATCTATACATCAGCTTTTTGCTATAATCCTTTTATCTATAATAATTTGGTGCTATTTTTTAATAAACAGTAGTTAA

Upstream 100 bases:

>100_bases
TTTGCAGGAATGACAAGATAAAAAATATAAACTTAAAATAAAAGTGCGGAAAAGCTTAATTACAAAATGGTTGTTTGTAA
GCTGTATAATGGTCATAGCG

Downstream 100 bases:

>100_bases
AATATTACTATGGTTAAGTCAGCATTGTTGCGTTGATACCAAGTTGTAATTGCAAGGAGCGAAGCAACGCAGCAATCCAG
TGATACAAATTCTGTAAATC

Product: cytochrome c oxidase assembly protein

Products: NA

Alternate protein names: HAS; Cytochrome aa3-controlling protein

Number of amino acids: Translated: 318; Mature: 318

Protein sequence:

>318_residues
MVVIGGITRLTGAGLSIVEWRPVTGILPPFSFESWQAEFAKYKAFPEYNSVNYGMTLSEFKCIYLLEFIHRLLGRMTVLI
YIVPLIYFYFKDVIKNCDMLPYIIALLLFCVQGFMGWYMVKSGLLNSPSVSHFRLAFHLIIAVIIYHILFYQLIKNRCDI
LLIPSQTDLKLPLIFSGIAITVIYVQIFLGALVAGLDAGLIYNSFPLMGDHCIPMEIKDNFFNLANLHDPVFIQFIHRLG
SYSVFLVVVVLVICLLTIEHPKLNKIAYFLMIALLMQISTGIITLLYSVPIIIASIHQLFAIILLSIIIWCYFLINSS

Sequences:

>Translated_318_residues
MVVIGGITRLTGAGLSIVEWRPVTGILPPFSFESWQAEFAKYKAFPEYNSVNYGMTLSEFKCIYLLEFIHRLLGRMTVLI
YIVPLIYFYFKDVIKNCDMLPYIIALLLFCVQGFMGWYMVKSGLLNSPSVSHFRLAFHLIIAVIIYHILFYQLIKNRCDI
LLIPSQTDLKLPLIFSGIAITVIYVQIFLGALVAGLDAGLIYNSFPLMGDHCIPMEIKDNFFNLANLHDPVFIQFIHRLG
SYSVFLVVVVLVICLLTIEHPKLNKIAYFLMIALLMQISTGIITLLYSVPIIIASIHQLFAIILLSIIIWCYFLINSS
>Mature_318_residues
MVVIGGITRLTGAGLSIVEWRPVTGILPPFSFESWQAEFAKYKAFPEYNSVNYGMTLSEFKCIYLLEFIHRLLGRMTVLI
YIVPLIYFYFKDVIKNCDMLPYIIALLLFCVQGFMGWYMVKSGLLNSPSVSHFRLAFHLIIAVIIYHILFYQLIKNRCDI
LLIPSQTDLKLPLIFSGIAITVIYVQIFLGALVAGLDAGLIYNSFPLMGDHCIPMEIKDNFFNLANLHDPVFIQFIHRLG
SYSVFLVVVVLVICLLTIEHPKLNKIAYFLMIALLMQISTGIITLLYSVPIIIASIHQLFAIILLSIIIWCYFLINSS

Specific function: Catalyzes the oxidation of the C8 methyl side group on heme O porphyrin ring into a formyl group

COG id: COG1612

COG function: function code O; Uncharacterized protein required for cytochrome oxidase assembly

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the COX15/CtaA family. Type 2 subfamily

Homologues:

Organism=Homo sapiens, GI17921985, Length=318, Percent_Identity=38.0503144654088, Blast_Score=209, Evalue=2e-54,
Organism=Homo sapiens, GI17921987, Length=281, Percent_Identity=38.0782918149466, Blast_Score=189, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI17536069, Length=325, Percent_Identity=36, Blast_Score=191, Evalue=6e-49,
Organism=Saccharomyces cerevisiae, GI6320989, Length=340, Percent_Identity=35, Blast_Score=186, Evalue=4e-48,
Organism=Drosophila melanogaster, GI19922860, Length=330, Percent_Identity=36.3636363636364, Blast_Score=192, Evalue=2e-49,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): CTAA_RICAH (A8GMQ9)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493192.1
- STRING:   A8GMQ9
- GeneID:   5645207
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_01865
- NMPDR:   fig|293614.3.peg.348
- eggNOG:   COG1612
- HOGENOM:   HBG628966
- ProtClustDB:   CLSK864993
- BioCyc:   RAKA293614:A1C_01865-MONOMER
- HAMAP:   MF_01665
- InterPro:   IPR003780

Pfam domain/function: PF02628 COX15-CtaA

EC number: NA

Molecular weight: Translated: 36211; Mature: 36211

Theoretical pI: Translated: 8.06; Mature: 8.06

Prosite motif: NA

Important sites: BINDING 316-316

Signals:

None

Transmembrane regions:

HASH(0x95a3cfc)-; HASH(0x1249633c)-; HASH(0x126f5c08)-; HASH(0x11b23534)-; HASH(0x11765294)-; HASH(0x11a37e44)-; HASH(0x1275562c)-; HASH(0x127bbca8)-;

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVVIGGITRLTGAGLSIVEWRPVTGILPPFSFESWQAEFAKYKAFPEYNSVNYGMTLSEF
CEEECCHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHH
KCIYLLEFIHRLLGRMTVLIYIVPLIYFYFKDVIKNCDMLPYIIALLLFCVQGFMGWYMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KSGLLNSPSVSHFRLAFHLIIAVIIYHILFYQLIKNRCDILLIPSQTDLKLPLIFSGIAI
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHH
TVIYVQIFLGALVAGLDAGLIYNSFPLMGDHCIPMEIKDNFFNLANLHDPVFIQFIHRLG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHCCHHHHHCCCCHHHHHHHHHHC
SYSVFLVVVVLVICLLTIEHPKLNKIAYFLMIALLMQISTGIITLLYSVPIIIASIHQLF
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIILLSIIIWCYFLINSS
HHHHHHHHHHHHHHHCCH
>Mature Secondary Structure
MVVIGGITRLTGAGLSIVEWRPVTGILPPFSFESWQAEFAKYKAFPEYNSVNYGMTLSEF
CEEECCHHHHHCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHH
KCIYLLEFIHRLLGRMTVLIYIVPLIYFYFKDVIKNCDMLPYIIALLLFCVQGFMGWYMV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHH
KSGLLNSPSVSHFRLAFHLIIAVIIYHILFYQLIKNRCDILLIPSQTDLKLPLIFSGIAI
HHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCHHHHHHHHH
TVIYVQIFLGALVAGLDAGLIYNSFPLMGDHCIPMEIKDNFFNLANLHDPVFIQFIHRLG
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHCCHHHHHCCCCHHHHHHHHHHC
SYSVFLVVVVLVICLLTIEHPKLNKIAYFLMIALLMQISTGIITLLYSVPIIIASIHQLF
CHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AIILLSIIIWCYFLINSS
HHHHHHHHHHHHHHHCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA