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The map label for this gene is fmt [H]

Identifier: 157825412

GI number: 157825412

Start: 286415

End: 287311

Strand: Direct

Name: fmt [H]

Synonym: A1C_01565

Alternate gene names: 157825412

Gene position: 286415-287311 (Clockwise)

Preceding gene: 157825411

Following gene: 157825413

Centisome position: 23.27

GC content: 33.67

Gene sequence:

>897_bases
ATGGGAACGCCTGAATTTGCAGTCCCAGCTCTTAAAAAACTTATAATGCATCATGAAGTTAAAGTTGTTTTTACCCAGCA
ACCTAAAGCTAAGGGCAGAGGACTTGACTTAGTTAAATCCCCAATACATCAGTTAGCATTTGAGCATCAAATTCCTGTTT
ATACTCCCTCTACACTTCGTAATGATGACATAGTTAATCTAATTAATAAGATTAATGCAGATATTATAGTTGTTATTGCA
TATGGTTTTATTTTGCCAAAAGCTATATTAGAGGATAAAAAATACGGCTGTCTTAATATCCATCCATCTGATTTGCCTCG
TCATAGAGGAGCAGCACCGCTGCAGCGTACTATTATAGAGGGTGACCGGAAAAGTAGTGTATGTATTATGCGTATGGATA
CAGGAATTGATACAGGTGATATATTGATGAAAGAAGATTTTTATTTAGAAAGAAGAACAACATTGGAGGAATTGCACAAT
AAATGTGCTAATTTAGGAGCTGCATTACTAATAAGAACACTTGCAAATATTGATAATATAGTACCGATAAAACAGTCAAG
TGAGGGCGTTACGTATGCTAATAAATTAACTAAAGAAGAAGGAAAAATTAATTGGCATGAATCCGCATATAAAATAGATT
GTAAAATAAGGGGTATGAATCCCTGGCCCGGAGCATATTTTAGTTATAATGATAAAGTAATTAAAATCCTTGAAGCAGAA
TATTTAAATACGAATCATCACGTTACTGCCGGCACCGTTATTAGCGATAAGCTGGAAATAGCTTGTGGAAGCGGTATATT
GCAAGTGAAAAAACTTCAGCAAGAGAGTAAAAAAGCTTTGAATGTAGAAGAATTTTTACGTGGTACAAATATTTTAAAAG
CTACAATATTAAAATAA

Upstream 100 bases:

>100_bases
AAGGTAAGCTCATGATTGATTATTTAAGTAATTTAAAACGAGATGTGGTGCTTCGTAAGCTCAAGAAACTTAAAAATAAT
ATAGTGTGAAAGTAATCTTT

Downstream 100 bases:

>100_bases
TAGTATTAATTATGAGTAAAGGTAAACAAGAAGTTAGGTTTAACGATAATTTAGACGTTAAGTAGTTTAGCTTAAAGTTT
GAAAACAATAGTGATATTTA

Product: methionyl-tRNA formyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 298; Mature: 297

Protein sequence:

>298_residues
MGTPEFAVPALKKLIMHHEVKVVFTQQPKAKGRGLDLVKSPIHQLAFEHQIPVYTPSTLRNDDIVNLINKINADIIVVIA
YGFILPKAILEDKKYGCLNIHPSDLPRHRGAAPLQRTIIEGDRKSSVCIMRMDTGIDTGDILMKEDFYLERRTTLEELHN
KCANLGAALLIRTLANIDNIVPIKQSSEGVTYANKLTKEEGKINWHESAYKIDCKIRGMNPWPGAYFSYNDKVIKILEAE
YLNTNHHVTAGTVISDKLEIACGSGILQVKKLQQESKKALNVEEFLRGTNILKATILK

Sequences:

>Translated_298_residues
MGTPEFAVPALKKLIMHHEVKVVFTQQPKAKGRGLDLVKSPIHQLAFEHQIPVYTPSTLRNDDIVNLINKINADIIVVIA
YGFILPKAILEDKKYGCLNIHPSDLPRHRGAAPLQRTIIEGDRKSSVCIMRMDTGIDTGDILMKEDFYLERRTTLEELHN
KCANLGAALLIRTLANIDNIVPIKQSSEGVTYANKLTKEEGKINWHESAYKIDCKIRGMNPWPGAYFSYNDKVIKILEAE
YLNTNHHVTAGTVISDKLEIACGSGILQVKKLQQESKKALNVEEFLRGTNILKATILK
>Mature_297_residues
GTPEFAVPALKKLIMHHEVKVVFTQQPKAKGRGLDLVKSPIHQLAFEHQIPVYTPSTLRNDDIVNLINKINADIIVVIAY
GFILPKAILEDKKYGCLNIHPSDLPRHRGAAPLQRTIIEGDRKSSVCIMRMDTGIDTGDILMKEDFYLERRTTLEELHNK
CANLGAALLIRTLANIDNIVPIKQSSEGVTYANKLTKEEGKINWHESAYKIDCKIRGMNPWPGAYFSYNDKVIKILEAEY
LNTNHHVTAGTVISDKLEIACGSGILQVKKLQQESKKALNVEEFLRGTNILKATILK

Specific function: Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by:(I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-

COG id: COG0223

COG function: function code J; Methionyl-tRNA formyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fmt family [H]

Homologues:

Organism=Homo sapiens, GI164663775, Length=314, Percent_Identity=28.6624203821656, Blast_Score=103, Evalue=2e-22,
Organism=Homo sapiens, GI21614513, Length=303, Percent_Identity=28.3828382838284, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI238814322, Length=236, Percent_Identity=29.2372881355932, Blast_Score=95, Evalue=6e-20,
Organism=Escherichia coli, GI1789683, Length=291, Percent_Identity=40.5498281786942, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI1788589, Length=256, Percent_Identity=27.734375, Blast_Score=103, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI133930964, Length=254, Percent_Identity=28.740157480315, Blast_Score=84, Evalue=6e-17,
Organism=Saccharomyces cerevisiae, GI6319458, Length=243, Percent_Identity=29.2181069958848, Blast_Score=66, Evalue=6e-12,
Organism=Drosophila melanogaster, GI28571984, Length=227, Percent_Identity=31.2775330396476, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI45550868, Length=227, Percent_Identity=31.2775330396476, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI24585660, Length=237, Percent_Identity=26.5822784810127, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005794
- InterPro:   IPR005793
- InterPro:   IPR002376
- InterPro:   IPR011034
- InterPro:   IPR015518 [H]

Pfam domain/function: PF02911 Formyl_trans_C; PF00551 Formyl_trans_N [H]

EC number: =2.1.2.9 [H]

Molecular weight: Translated: 33433; Mature: 33302

Theoretical pI: Translated: 9.08; Mature: 9.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGTPEFAVPALKKLIMHHEVKVVFTQQPKAKGRGLDLVKSPIHQLAFEHQIPVYTPSTLR
CCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
NDDIVNLINKINADIIVVIAYGFILPKAILEDKKYGCLNIHPSDLPRHRGAAPLQRTIIE
CCHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHC
GDRKSSVCIMRMDTGIDTGDILMKEDFYLERRTTLEELHNKCANLGAALLIRTLANIDNI
CCCCCCEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VPIKQSSEGVTYANKLTKEEGKINWHESAYKIDCKIRGMNPWPGAYFSYNDKVIKILEAE
ECCCCCCCCCHHHHHHHHCCCCEEECCCEEEEEEEEECCCCCCCCCEECCCCEEEEEEHH
YLNTNHHVTAGTVISDKLEIACGSGILQVKKLQQESKKALNVEEFLRGTNILKATILK
HCCCCCEEEECEEECCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHCCCCHHEEEECC
>Mature Secondary Structure 
GTPEFAVPALKKLIMHHEVKVVFTQQPKAKGRGLDLVKSPIHQLAFEHQIPVYTPSTLR
CCCCHHHHHHHHHHHHCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCC
NDDIVNLINKINADIIVVIAYGFILPKAILEDKKYGCLNIHPSDLPRHRGAAPLQRTIIE
CCHHHHHHHHCCCCEEEEEHHHHHHHHHHHCCCCCCEEECCCCCCCCCCCCCHHHHHHHC
GDRKSSVCIMRMDTGIDTGDILMKEDFYLERRTTLEELHNKCANLGAALLIRTLANIDNI
CCCCCCEEEEEECCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
VPIKQSSEGVTYANKLTKEEGKINWHESAYKIDCKIRGMNPWPGAYFSYNDKVIKILEAE
ECCCCCCCCCHHHHHHHHCCCCEEECCCEEEEEEEEECCCCCCCCCEECCCCEEEEEEHH
YLNTNHHVTAGTVISDKLEIACGSGILQVKKLQQESKKALNVEEFLRGTNILKATILK
HCCCCCEEEECEEECCCEEEEECCCHHHHHHHHHHHHHCCCHHHHHCCCCHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA