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The map label for this gene is rnhB

Identifier: 157825403

GI number: 157825403

Start: 275014

End: 275595

Strand: Direct

Name: rnhB

Synonym: A1C_01485

Alternate gene names: 157825403

Gene position: 275014-275595 (Clockwise)

Preceding gene: 157825396

Following gene: 157825405

Centisome position: 22.34

GC content: 33.33

Gene sequence:

>582_bases
ATGGAAGTAGACCTATTACATTTTGAAAAAAAATATCATAACTATATTGTAGCAGGTATAGATGAAGCAGGTAGAGGACC
CCTAGCAGGTCCGGTGGTCGCAAGTGCCGTTATAATAGATAACGCTAATATTATACATGGCATTAAGGATTCTAAAAAGC
TTTCTAAAAAGAAAAGAGCATTACTATATGAGCAAATAACTAGTAATTATGTTTGGGCAGTTGCTATTATTACCCACACC
GAAATTGATAAGATCAATATATTAGAGGCAACTAAAAAAGCTTGTTCTATTGCTGCAGCAAATCTTAATGTTAAGCCTGA
AATAGTTTTAGTTGACGGTAATATGCAGTTTAGTGATGAAAGATTTATCAGTATAGTTAACGGTGATAATTTATCGTTAT
CAATTGCAGCAGCTTCTATTATCGCAAAAGTTACTAGGGATCGTTTGATGCTAGAATTAAGTGCTAAATTTCCACAATAT
TTATGGCACAAAAATTCCGGTTACGGTACCAAAGAGCATCTAGAAGCTATTAATAAATACGGCTTATCACCGTATCATAG
AAAAAGCTTTAAGTGTTGTTAA

Upstream 100 bases:

>100_bases
TTTATGTCACGCCTGCGAAAGCTGGAATGACATAATCCATGCAGCGATATCAATTTTTTAAATTAAGCTAGTATACATTA
AAAATTAAAAAAATACAATT

Downstream 100 bases:

>100_bases
TGTGCGTTGTTGTATGGATAGAAAAACCTTCTGGGGGTCATCCCGTGGCTTGACCACGGGATCCAGAAAAAAGCGAAATA
AATCGAGCTTTTAGTTTTAA

Product: ribonuclease HII

Products: NA

Alternate protein names: RNase HII

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MEVDLLHFEKKYHNYIVAGIDEAGRGPLAGPVVASAVIIDNANIIHGIKDSKKLSKKKRALLYEQITSNYVWAVAIITHT
EIDKINILEATKKACSIAAANLNVKPEIVLVDGNMQFSDERFISIVNGDNLSLSIAAASIIAKVTRDRLMLELSAKFPQY
LWHKNSGYGTKEHLEAINKYGLSPYHRKSFKCC

Sequences:

>Translated_193_residues
MEVDLLHFEKKYHNYIVAGIDEAGRGPLAGPVVASAVIIDNANIIHGIKDSKKLSKKKRALLYEQITSNYVWAVAIITHT
EIDKINILEATKKACSIAAANLNVKPEIVLVDGNMQFSDERFISIVNGDNLSLSIAAASIIAKVTRDRLMLELSAKFPQY
LWHKNSGYGTKEHLEAINKYGLSPYHRKSFKCC
>Mature_193_residues
MEVDLLHFEKKYHNYIVAGIDEAGRGPLAGPVVASAVIIDNANIIHGIKDSKKLSKKKRALLYEQITSNYVWAVAIITHT
EIDKINILEATKKACSIAAANLNVKPEIVLVDGNMQFSDERFISIVNGDNLSLSIAAASIIAKVTRDRLMLELSAKFPQY
LWHKNSGYGTKEHLEAINKYGLSPYHRKSFKCC

Specific function: Endonuclease that specifically degrades the RNA of RNA- DNA hybrids

COG id: COG0164

COG function: function code L; Ribonuclease HII

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNase HII family

Homologues:

Organism=Escherichia coli, GI1786380, Length=180, Percent_Identity=46.6666666666667, Blast_Score=154, Evalue=4e-39,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RNH2_RICAH (A8GMJ0)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493123.1
- ProteinModelPortal:   A8GMJ0
- SMR:   A8GMJ0
- STRING:   A8GMJ0
- GeneID:   5644930
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_01485
- NMPDR:   fig|293614.3.peg.279
- eggNOG:   COG0164
- HOGENOM:   HBG584843
- OMA:   RLGPTPI
- ProtClustDB:   PRK00015
- BioCyc:   RAKA293614:A1C_01485-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00052_B
- InterPro:   IPR022898
- InterPro:   IPR001352
- InterPro:   IPR012337
- PANTHER:   PTHR10954

Pfam domain/function: PF01351 RNase_HII; SSF53098 RNaseH_fold

EC number: =3.1.26.4

Molecular weight: Translated: 21470; Mature: 21470

Theoretical pI: Translated: 9.28; Mature: 9.28

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEVDLLHFEKKYHNYIVAGIDEAGRGPLAGPVVASAVIIDNANIIHGIKDSKKLSKKKRA
CCCCHHHHHHHHCCEEEEECCCCCCCCCCCHHHHEEEEEECCCEEECCCCHHHHHHHHHH
LLYEQITSNYVWAVAIITHTEIDKINILEATKKACSIAAANLNVKPEIVLVDGNMQFSDE
HHHHHHHCCEEEEEEEEEECCCCEEHHHHHHHHHHHEEEECCCCCCEEEEEECCCEECCC
RFISIVNGDNLSLSIAAASIIAKVTRDRLMLELSAKFPQYLWHKNSGYGTKEHLEAINKY
EEEEEECCCCEEEEHHHHHHHHHHHHHHHEEEHHHCCCHHHHCCCCCCCHHHHHHHHHHH
GLSPYHRKSFKCC
CCCCCCCCCCCCC
>Mature Secondary Structure
MEVDLLHFEKKYHNYIVAGIDEAGRGPLAGPVVASAVIIDNANIIHGIKDSKKLSKKKRA
CCCCHHHHHHHHCCEEEEECCCCCCCCCCCHHHHEEEEEECCCEEECCCCHHHHHHHHHH
LLYEQITSNYVWAVAIITHTEIDKINILEATKKACSIAAANLNVKPEIVLVDGNMQFSDE
HHHHHHHCCEEEEEEEEEECCCCEEHHHHHHHHHHHEEEECCCCCCEEEEEECCCEECCC
RFISIVNGDNLSLSIAAASIIAKVTRDRLMLELSAKFPQYLWHKNSGYGTKEHLEAINKY
EEEEEECCCCEEEEHHHHHHHHHHHHHHHEEEHHHCCCHHHHCCCCCCCHHHHHHHHHHH
GLSPYHRKSFKCC
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA