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The map label for this gene is dapD

Identifier: 157825383

GI number: 157825383

Start: 261266

End: 262090

Strand: Direct

Name: dapD

Synonym: A1C_01385

Alternate gene names: 157825383

Gene position: 261266-262090 (Clockwise)

Preceding gene: 157825381

Following gene: 157825389

Centisome position: 21.22

GC content: 35.39

Gene sequence:

>825_bases
ATGTCATCTCTTATTAAAGAAATTGAAGAAGCTTGGCAAATTAAGGGCCAACTTCTTCAAGATTCTTCAAAGCTTATAAT
GTTAAAAAAAACACTTAATGATGTTATAGCAAGCTTAAATCAAGGTGCAATTCGTGTTTGTGAAAAGAAAGAAAATAGTT
GGGAAGTTAATGAATGGGTAAAGAAAGCTATATTGCTATATTTTATCACTACAGAATCACAACTGTATAATAACAATTAT
AATAGTTGGTATGACAAAGTTGCTCCTAAATTTTCTGTGGATACTGATGAAAATATATTCAAAGAAGCAGCTATACGTAA
AGTTCCCGGAGCTGTTGTCAGAACCGGTACTTATATAGCTAAAAATGTTGTAATTATGCCTTCTTTCATTAATATAGGTG
CTTATATAGATGAGGGAACAATGATTGATACATGGGCTACTATCGGCTCATGTGCTCAAATCGGTAAGCATTGCCATATT
TCAGGTGGTACAGGAATAGGAGGGGTGCTTGAACCTCTACAAGCAAAGCCCGTGATCATTGAAGATAATTGTTTTATCGG
TGCAAGATCGGAAATAGCAGAAGGGGTAATAGTAGAAGAAGGAGCAGTAATTAGTATGGGAGTGTTTATCGGTAGCTCTA
CAAAAATAATATACAGAGATACAGGTGAAATTATTTATGGTAGAATTCCGGCTTATTCTGTTGTAGTTCCAGGAGTATTA
CCTGCTAAGGAAGCAGGCAAGCCTGGGCTTTACTGCGCCGTCATCATAAAGCAAGTCGATAAAACTACTAGATCTAAAGT
AAGTATTAATGATTTGTTAAGGTGA

Upstream 100 bases:

>100_bases
GGGCAAGTAATATACATAGTTAATTATAATTATTATGTTTGACTGCATATGCATATGATAGCCTTATTTATTATTTTTTG
CAATAAAACAGTGAAAAGAT

Downstream 100 bases:

>100_bases
TGGTCCACTGTCACCTAGTTCGTTTGACCAGCGTTGTTGCATGGCTCAAGAAAAGTACTCGGTGTCATTCCTGCGGAAGC
AGGAATCCAGCATAAAGCGA

Product: 2,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase

Products: NA

Alternate protein names: Tetrahydrodipicolinate N-succinyltransferase; THDP succinyltransferase; THP succinyltransferase; Tetrahydropicolinate succinylase

Number of amino acids: Translated: 274; Mature: 273

Protein sequence:

>274_residues
MSSLIKEIEEAWQIKGQLLQDSSKLIMLKKTLNDVIASLNQGAIRVCEKKENSWEVNEWVKKAILLYFITTESQLYNNNY
NSWYDKVAPKFSVDTDENIFKEAAIRKVPGAVVRTGTYIAKNVVIMPSFINIGAYIDEGTMIDTWATIGSCAQIGKHCHI
SGGTGIGGVLEPLQAKPVIIEDNCFIGARSEIAEGVIVEEGAVISMGVFIGSSTKIIYRDTGEIIYGRIPAYSVVVPGVL
PAKEAGKPGLYCAVIIKQVDKTTRSKVSINDLLR

Sequences:

>Translated_274_residues
MSSLIKEIEEAWQIKGQLLQDSSKLIMLKKTLNDVIASLNQGAIRVCEKKENSWEVNEWVKKAILLYFITTESQLYNNNY
NSWYDKVAPKFSVDTDENIFKEAAIRKVPGAVVRTGTYIAKNVVIMPSFINIGAYIDEGTMIDTWATIGSCAQIGKHCHI
SGGTGIGGVLEPLQAKPVIIEDNCFIGARSEIAEGVIVEEGAVISMGVFIGSSTKIIYRDTGEIIYGRIPAYSVVVPGVL
PAKEAGKPGLYCAVIIKQVDKTTRSKVSINDLLR
>Mature_273_residues
SSLIKEIEEAWQIKGQLLQDSSKLIMLKKTLNDVIASLNQGAIRVCEKKENSWEVNEWVKKAILLYFITTESQLYNNNYN
SWYDKVAPKFSVDTDENIFKEAAIRKVPGAVVRTGTYIAKNVVIMPSFINIGAYIDEGTMIDTWATIGSCAQIGKHCHIS
GGTGIGGVLEPLQAKPVIIEDNCFIGARSEIAEGVIVEEGAVISMGVFIGSSTKIIYRDTGEIIYGRIPAYSVVVPGVLP
AKEAGKPGLYCAVIIKQVDKTTRSKVSINDLLR

Specific function: Biosynthesis of diaminopimelate and lysine from aspartate semialdehyde; fourth step. [C]

COG id: COG2171

COG function: function code E; Tetrahydrodipicolinate N-succinyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transferase hexapeptide repeat family

Homologues:

Organism=Escherichia coli, GI1786362, Length=274, Percent_Identity=57.2992700729927, Blast_Score=295, Evalue=3e-81,

Paralogues:

None

Copy number: 420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): DAPD_RICAH (A8GMH0)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493103.1
- ProteinModelPortal:   A8GMH0
- SMR:   A8GMH0
- STRING:   A8GMH0
- GeneID:   5644770
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_01385
- NMPDR:   fig|293614.3.peg.262
- eggNOG:   COG2171
- HOGENOM:   HBG704071
- OMA:   IMPSFIN
- ProtClustDB:   PRK11830
- BioCyc:   RAKA293614:A1C_01385-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00811
- InterPro:   IPR005664
- InterPro:   IPR023180
- InterPro:   IPR011004
- Gene3D:   G3DSA:1.10.166.10
- TIGRFAMs:   TIGR00965

Pfam domain/function: SSF51161 Trimer_LpxA_like

EC number: =2.3.1.117

Molecular weight: Translated: 30035; Mature: 29904

Theoretical pI: Translated: 7.24; Mature: 7.24

Prosite motif: PS00101 HEXAPEP_TRANSFERASES

Important sites: BINDING 106-106 BINDING 143-143

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLIKEIEEAWQIKGQLLQDSSKLIMLKKTLNDVIASLNQGAIRVCEKKENSWEVNEWV
CHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCEEHHHCCCCCCCHHHHH
KKAILLYFITTESQLYNNNYNSWYDKVAPKFSVDTDENIFKEAAIRKVPGAVVRTGTYIA
HHHEEEEEEECCHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEECCHHHH
KNVVIMPSFINIGAYIDEGTMIDTWATIGSCAQIGKHCHISGGTGIGGVLEPLQAKPVII
CCEEEEECHHCCCEEECCCCEEEHHHHHHHHHHHCCEEEECCCCCCCHHHHCCCCCCEEE
EDNCFIGARSEIAEGVIVEEGAVISMGVFIGSSTKIIYRDTGEIIYGRIPAYSVVVPGVL
ECCCEECCHHHHHCCEEEECCCEEEEEEEECCCCEEEEECCCCEEEECCCEEEEEECCCC
PAKEAGKPGLYCAVIIKQVDKTTRSKVSINDLLR
CCHHCCCCCEEHHHHHHHHHHHHHCEECHHHHCC
>Mature Secondary Structure 
SSLIKEIEEAWQIKGQLLQDSSKLIMLKKTLNDVIASLNQGAIRVCEKKENSWEVNEWV
HHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHHHHHCCCCCEEHHHCCCCCCCHHHHH
KKAILLYFITTESQLYNNNYNSWYDKVAPKFSVDTDENIFKEAAIRKVPGAVVRTGTYIA
HHHEEEEEEECCHHHHCCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCHHEECCHHHH
KNVVIMPSFINIGAYIDEGTMIDTWATIGSCAQIGKHCHISGGTGIGGVLEPLQAKPVII
CCEEEEECHHCCCEEECCCCEEEHHHHHHHHHHHCCEEEECCCCCCCHHHHCCCCCCEEE
EDNCFIGARSEIAEGVIVEEGAVISMGVFIGSSTKIIYRDTGEIIYGRIPAYSVVVPGVL
ECCCEECCHHHHHCCEEEECCCEEEEEEEECCCCEEEEECCCCEEEECCCEEEEEECCCC
PAKEAGKPGLYCAVIIKQVDKTTRSKVSINDLLR
CCHHCCCCCEEHHHHHHHHHHHHHCEECHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA