Click here to switch to the map view.

The map label for this gene is ackA

Identifier: 157825284

GI number: 157825284

Start: 156420

End: 157577

Strand: Direct

Name: ackA

Synonym: A1C_00830

Alternate gene names: 157825284

Gene position: 156420-157577 (Clockwise)

Preceding gene: 157825283

Following gene: 157825285

Centisome position: 12.71

GC content: 33.42

Gene sequence:

>1158_bases
ATGAAAGATGTTATTTTAATAGCTAATGCCGGCTCATCTAGTTTAAAAATTTCTATTTTTGAAATTCAGAATAAACAAGT
TAAGGATAAAATTTATAATATTTTTTTAGAAAAGAACGACAATAAAATATTATGTTATATAAATAAAAAACAGGAATCTG
CTACCGATATTAAAGATGATGCTATTGAAATGATGATTGATCTTTTTGAAGATTGGTGGAAAAAACAAGAGAATCTCAAT
TTAATTGCAACCGGTCACCGTATTGTCCATGGCGGGAAAAATTTTAATAAACCGGTTATTGTTAATGAAAAAGTGAGTGA
AGATTTGAGAGTATTAATACCTCTAAACCCTTTGCATCAACCTTATAATTTGCAGGTACTGGATTTATTTCTTCAAAAAT
ATAAAGAAATCGTGCATATAGCATGTTTTGATACGTCGTTTCATTTTACCAATCCGCCTATTACAAAAGCTTTCGGTTTA
CCGAAAAAATATTATGCTAAAGGGATAATTCGTTACGGTTTTCATGGATTATCATATAAATATGTTAGTAGCCATTTTAA
AGAAATGACTAAGGAAGATTTACCTATAAAGACTATTATAGCTCACTTAGGAAGTGGTAGTAGTCTATGTGCTATTAAAA
ACGGTCTTAGTCTAACAAGTTCTATGGGCTTTAGCGTACTCGACGGTGTTATGATGGGTACAAGGACAGGTAACATCGAT
CCCGGAATAGTGTTGTATCTTATCGATCATGAGAAAATGACTACGAAAGAAATAACCGAGTTATTATATAAGAAGTCGGG
GTTACTCGGTATATCCGGCGAAAGCTCCGATATTCGTACTTTGCTTGCCAGTAACTCACCTGATGCTAAATTTGCTATAG
ATTTATTCGTGTATCGCATTGTCCTTGAAATAGGTAAGTTAACTGCTGCACTTGAGGGGATTGATGGTCTAATTTTTACC
GCCGGTGTCGGACAGAATTCTGCTGTAATACGTGAGATGATTAGCGCAAAACTTTCATGGCTAGGCATTAAAATAGATGA
TACAAAAAACCAAAAAAACGAGCATTTAATAAGTACTGAAAGCAGTAAGGTTAAAGTTTTTGCTGTGCCGACAAACGAAG
AGCTAATCATCGCTGAGGAAGTGATAAAGTTTTTATAA

Upstream 100 bases:

>100_bases
AGAGCAGATCCAATGGATATGCGTGTTATTGCCTGTGTGCTTGCTTCATTTATTTATAATCATACTAAGGCGAAGCTACA
TAGCCAATCAGGTAGATAAT

Downstream 100 bases:

>100_bases
CACAAATTAGTTAATTTTTAATTATTTATATCTTTATATTTTCTTTATTAACTTTTTTTTGAAATACAATATATGCAAGT
ATAGATATATTTTGAACTTG

Product: acetate kinase

Products: NA

Alternate protein names: Acetokinase

Number of amino acids: Translated: 385; Mature: 385

Protein sequence:

>385_residues
MKDVILIANAGSSSLKISIFEIQNKQVKDKIYNIFLEKNDNKILCYINKKQESATDIKDDAIEMMIDLFEDWWKKQENLN
LIATGHRIVHGGKNFNKPVIVNEKVSEDLRVLIPLNPLHQPYNLQVLDLFLQKYKEIVHIACFDTSFHFTNPPITKAFGL
PKKYYAKGIIRYGFHGLSYKYVSSHFKEMTKEDLPIKTIIAHLGSGSSLCAIKNGLSLTSSMGFSVLDGVMMGTRTGNID
PGIVLYLIDHEKMTTKEITELLYKKSGLLGISGESSDIRTLLASNSPDAKFAIDLFVYRIVLEIGKLTAALEGIDGLIFT
AGVGQNSAVIREMISAKLSWLGIKIDDTKNQKNEHLISTESSKVKVFAVPTNEELIIAEEVIKFL

Sequences:

>Translated_385_residues
MKDVILIANAGSSSLKISIFEIQNKQVKDKIYNIFLEKNDNKILCYINKKQESATDIKDDAIEMMIDLFEDWWKKQENLN
LIATGHRIVHGGKNFNKPVIVNEKVSEDLRVLIPLNPLHQPYNLQVLDLFLQKYKEIVHIACFDTSFHFTNPPITKAFGL
PKKYYAKGIIRYGFHGLSYKYVSSHFKEMTKEDLPIKTIIAHLGSGSSLCAIKNGLSLTSSMGFSVLDGVMMGTRTGNID
PGIVLYLIDHEKMTTKEITELLYKKSGLLGISGESSDIRTLLASNSPDAKFAIDLFVYRIVLEIGKLTAALEGIDGLIFT
AGVGQNSAVIREMISAKLSWLGIKIDDTKNQKNEHLISTESSKVKVFAVPTNEELIIAEEVIKFL
>Mature_385_residues
MKDVILIANAGSSSLKISIFEIQNKQVKDKIYNIFLEKNDNKILCYINKKQESATDIKDDAIEMMIDLFEDWWKKQENLN
LIATGHRIVHGGKNFNKPVIVNEKVSEDLRVLIPLNPLHQPYNLQVLDLFLQKYKEIVHIACFDTSFHFTNPPITKAFGL
PKKYYAKGIIRYGFHGLSYKYVSSHFKEMTKEDLPIKTIIAHLGSGSSLCAIKNGLSLTSSMGFSVLDGVMMGTRTGNID
PGIVLYLIDHEKMTTKEITELLYKKSGLLGISGESSDIRTLLASNSPDAKFAIDLFVYRIVLEIGKLTAALEGIDGLIFT
AGVGQNSAVIREMISAKLSWLGIKIDDTKNQKNEHLISTESSKVKVFAVPTNEELIIAEEVIKFL

Specific function: Anaerobic degradation of L-threonine to propionate. [C]

COG id: COG0282

COG function: function code C; Acetate kinase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acetokinase family

Homologues:

Organism=Escherichia coli, GI145693184, Length=399, Percent_Identity=36.5914786967419, Blast_Score=251, Evalue=6e-68,
Organism=Escherichia coli, GI1788633, Length=396, Percent_Identity=33.8383838383838, Blast_Score=218, Evalue=7e-58,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ACKA_RICAH (A8GM71)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001493004.1
- ProteinModelPortal:   A8GM71
- SMR:   A8GM71
- STRING:   A8GM71
- GeneID:   5645503
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_00830
- NMPDR:   fig|293614.3.peg.154
- eggNOG:   COG0282
- HOGENOM:   HBG285863
- OMA:   GNLDPIR
- ProtClustDB:   CLSK870749
- BioCyc:   RAKA293614:A1C_00830-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00020
- InterPro:   IPR000890
- InterPro:   IPR004372
- PANTHER:   PTHR21060
- PANTHER:   PTHR21060:SF11
- PIRSF:   PIRSF000722
- PRINTS:   PR00471
- TIGRFAMs:   TIGR00016

Pfam domain/function: PF00871 Acetate_kinase

EC number: =2.7.2.1

Molecular weight: Translated: 43119; Mature: 43119

Theoretical pI: Translated: 8.09; Mature: 8.09

Prosite motif: PS01075 ACETATE_KINASE_1; PS01076 ACETATE_KINASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKDVILIANAGSSSLKISIFEIQNKQVKDKIYNIFLEKNDNKILCYINKKQESATDIKDD
CCCEEEEEECCCCCEEEEEEEECCHHHHHHHEEEEEEECCCEEEEEEECCCCCCCCCHHH
AIEMMIDLFEDWWKKQENLNLIATGHRIVHGGKNFNKPVIVNEKVSEDLRVLIPLNPLHQ
HHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCEEECCCCCCCEEEEEECCCCCC
PYNLQVLDLFLQKYKEIVHIACFDTSFHFTNPPITKAFGLPKKYYAKGIIRYGFHGLSYK
CCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCHH
YVSSHFKEMTKEDLPIKTIIAHLGSGSSLCAIKNGLSLTSSMGFSVLDGVMMGTRTGNID
HHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCHHHHCCHHHHHHHHCCCCCCCCC
PGIVLYLIDHEKMTTKEITELLYKKSGLLGISGESSDIRTLLASNSPDAKFAIDLFVYRI
CCEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHEECCCCCCCHHHHHHHHHHH
VLEIGKLTAALEGIDGLIFTAGVGQNSAVIREMISAKLSWLGIKIDDTKNQKNEHLISTE
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEECC
SSKVKVFAVPTNEELIIAEEVIKFL
CCCEEEEEECCCCCEEEHHHHHHHC
>Mature Secondary Structure
MKDVILIANAGSSSLKISIFEIQNKQVKDKIYNIFLEKNDNKILCYINKKQESATDIKDD
CCCEEEEEECCCCCEEEEEEEECCHHHHHHHEEEEEEECCCEEEEEEECCCCCCCCCHHH
AIEMMIDLFEDWWKKQENLNLIATGHRIVHGGKNFNKPVIVNEKVSEDLRVLIPLNPLHQ
HHHHHHHHHHHHHHHCCCCEEEEECCEEEECCCCCCCCEEECCCCCCCEEEEEECCCCCC
PYNLQVLDLFLQKYKEIVHIACFDTSFHFTNPPITKAFGLPKKYYAKGIIRYGFHGLSYK
CCCHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHHHCCCHHHHHHHHHHHCCCCCCHH
YVSSHFKEMTKEDLPIKTIIAHLGSGSSLCAIKNGLSLTSSMGFSVLDGVMMGTRTGNID
HHHHHHHHHHHCCCCHHHHHHHCCCCCCEEEEECCCCHHHHCCHHHHHHHHCCCCCCCCC
PGIVLYLIDHEKMTTKEITELLYKKSGLLGISGESSDIRTLLASNSPDAKFAIDLFVYRI
CCEEEEEECCCCCCHHHHHHHHHHCCCCEEECCCCCHHHHEECCCCCCCHHHHHHHHHHH
VLEIGKLTAALEGIDGLIFTAGVGQNSAVIREMISAKLSWLGIKIDDTKNQKNEHLISTE
HHHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHHHEEEEEEECCCCCCCCEEEECC
SSKVKVFAVPTNEELIIAEEVIKFL
CCCEEEEEECCCCCEEEHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA