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The map label for this gene is alr [H]

Identifier: 157825267

GI number: 157825267

Start: 130846

End: 131913

Strand: Direct

Name: alr [H]

Synonym: A1C_00730

Alternate gene names: 157825267

Gene position: 130846-131913 (Clockwise)

Preceding gene: 157825266

Following gene: 157825268

Centisome position: 10.63

GC content: 33.8

Gene sequence:

>1068_bases
ATGAGCTTGTGTACTCTAGAGATAAATATATCTGCAATAAAAAATAATTATCTTTTATTACAAGGTATTTGTAAAACCTC
ATTAGTCGGTGCTGCAGTTAAAGCTAACGGTTACGGTCTTGGAGCAGTGCAAATTTCTAAAGCTTTAATAAAAGAAAATT
GTAGGTATTTTTTTGTAGCCACAAGCGAGGAGGGAGTGAATTTACGCAAAGCTTTAGGGTTAGATGTTGATATTTTAGTT
CTTAACGGCGTTTTTGAACATGATGCTTTAGAGCTTATAGAATATAATTTAACCCCTGTTCTAAATAACTTAAAACAAAT
AGAAATTTGGCAAAAATTTAGTAATTTGAAACATAGATTATTACCTTGTTATCTACATTTCAATACGGGTATTAATCGTC
TTGGCTTAAGCTCTGATGAGATAGAGCAGCTAATTAATGATCGTGATTTATTAAAAGGGCTAGATTTACAATATATTATA
AGCCATCTAGCTATCTCTGAAGAAATAGATAATCCTTATAATCTAGAGCAATTAAACATATTTAAAGCTTATTTACAATA
TTTCCCAAACGTCAAAGCAAGCCTTGCTAATTCCGGCGGCATATTTTTAGGGCAGGATTATCATTTTGATTTAGCAAGAC
CAGGTGCTGCTTTATATGGACTTAATCCTGTAATGAAAAATCCCGTAACCTTAAAAGCTCCGATAATTCATTTACAGAAT
TTGACACTAGATAGCCATATCGGTTATAATATGACTTTTACAACTAAGCGTGATAGTGTTATTGCAACGTTACCGCTTGG
TTATGCTGATGGGTTTAGTCGTAATTTTAGCAATCAAGGTGAAGTATTTATTAATGGTCGCAGCGTTCCCATAGTAGGGC
GAATATCGATGGATTTGATCAATATCGATGTTACCGATCTACCACCGCTTGATATTTTTCTAGGGCAGGAAGCAGAAATT
ATCGGAAATTATTGCACGCCCGATAAAATAGCGAGTATTATAGGTACTATAGGGTATGAGGTATTGACTAGTCTCGGTAG
TAGGTATAAGAGAATTTATATTGAGTAG

Upstream 100 bases:

>100_bases
TTGTTACCGATACTATAGAAGTAGGTGACTTACCTCCAAAATTTCGTATAATAGCGGTAATACCAATTATCGTAAAAGTA
AAAGAGTTAAGAACTATACT

Downstream 100 bases:

>100_bases
ATGCCTATGTGTGATGCCATTCTAGTGTATGAACGTTCAGGGTGTCATTCCTGCTTTTGCAGGAATCTAATAAAATATCT
TAAATATTTGGTATGAACAA

Product: alanine racemase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 355; Mature: 354

Protein sequence:

>355_residues
MSLCTLEINISAIKNNYLLLQGICKTSLVGAAVKANGYGLGAVQISKALIKENCRYFFVATSEEGVNLRKALGLDVDILV
LNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKHRLLPCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYII
SHLAISEEIDNPYNLEQLNIFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPVMKNPVTLKAPIIHLQN
LTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINGRSVPIVGRISMDLINIDVTDLPPLDIFLGQEAEI
IGNYCTPDKIASIIGTIGYEVLTSLGSRYKRIYIE

Sequences:

>Translated_355_residues
MSLCTLEINISAIKNNYLLLQGICKTSLVGAAVKANGYGLGAVQISKALIKENCRYFFVATSEEGVNLRKALGLDVDILV
LNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKHRLLPCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYII
SHLAISEEIDNPYNLEQLNIFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPVMKNPVTLKAPIIHLQN
LTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINGRSVPIVGRISMDLINIDVTDLPPLDIFLGQEAEI
IGNYCTPDKIASIIGTIGYEVLTSLGSRYKRIYIE
>Mature_354_residues
SLCTLEINISAIKNNYLLLQGICKTSLVGAAVKANGYGLGAVQISKALIKENCRYFFVATSEEGVNLRKALGLDVDILVL
NGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKHRLLPCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIIS
HLAISEEIDNPYNLEQLNIFKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPVMKNPVTLKAPIIHLQNL
TLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINGRSVPIVGRISMDLINIDVTDLPPLDIFLGQEAEII
GNYCTPDKIASIIGTIGYEVLTSLGSRYKRIYIE

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=367, Percent_Identity=29.700272479564, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1787439, Length=353, Percent_Identity=28.6118980169972, Blast_Score=137, Evalue=8e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 39491; Mature: 39360

Theoretical pI: Translated: 5.63; Mature: 5.63

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLCTLEINISAIKNNYLLLQGICKTSLVGAAVKANGYGLGAVQISKALIKENCRYFFVA
CCEEEEEEEEEEEECCEEEEEEHHHHHHHCEEEECCCCEECHHHHHHHHHHCCCEEEEEE
TSEEGVNLRKALGLDVDILVLNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKHRL
ECCCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHE
LPCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIISHLAISEEIDNPYNLEQLNI
EEEEEEECCCCCCCCCCHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHH
FKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPVMKNPVTLKAPIIHLQN
HHHHHHHCCCCCEECCCCCCEEEECCCEEECCCCCCEEECCCHHHCCCEEEEECEEEEEE
LTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINGRSVPIVGRISMDLI
EEECCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEEE
NIDVTDLPPLDIFLGQEAEIIGNYCTPDKIASIIGTIGYEVLTSLGSRYKRIYIE
EEEECCCCCCEEEECCCHHEECCCCCHHHHHHHHHHHHHHHHHHHCCHHEEEEEC
>Mature Secondary Structure 
SLCTLEINISAIKNNYLLLQGICKTSLVGAAVKANGYGLGAVQISKALIKENCRYFFVA
CEEEEEEEEEEEECCEEEEEEHHHHHHHCEEEECCCCEECHHHHHHHHHHCCCEEEEEE
TSEEGVNLRKALGLDVDILVLNGVFEHDALELIEYNLTPVLNNLKQIEIWQKFSNLKHRL
ECCCCCCHHHHHCCCEEEEEECCCCCHHHHHHHHCCCCHHHCCHHHHHHHHHHHHHHHHE
LPCYLHFNTGINRLGLSSDEIEQLINDRDLLKGLDLQYIISHLAISEEIDNPYNLEQLNI
EEEEEEECCCCCCCCCCHHHHHHHHCHHHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHH
FKAYLQYFPNVKASLANSGGIFLGQDYHFDLARPGAALYGLNPVMKNPVTLKAPIIHLQN
HHHHHHHCCCCCEECCCCCCEEEECCCEEECCCCCCEEECCCHHHCCCEEEEECEEEEEE
LTLDSHIGYNMTFTTKRDSVIATLPLGYADGFSRNFSNQGEVFINGRSVPIVGRISMDLI
EEECCCCCCEEEEEECCCCEEEEECCCCCCCCCCCCCCCCCEEECCCCCEEEEEEEEEEE
NIDVTDLPPLDIFLGQEAEIIGNYCTPDKIASIIGTIGYEVLTSLGSRYKRIYIE
EEEECCCCCCEEEECCCHHEECCCCCHHHHHHHHHHHHHHHHHHHCCHHEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA