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The map label for this gene is prs [C]

Identifier: 157825264

GI number: 157825264

Start: 130177

End: 130353

Strand: Direct

Name: prs [C]

Synonym: A1C_00715

Alternate gene names: 157825264

Gene position: 130177-130353 (Clockwise)

Preceding gene: 157825257

Following gene: 157825265

Centisome position: 10.57

GC content: 32.2

Gene sequence:

>177_bases
ATGCAGCAAACACAAGAGGCAGCAAGTCGAATAATTCTAGTAATGCCTTATTTCAGTTATGCAAGGCAAGATAGTATAAA
TTCTCAAAATATCATTCCTGCTAAGTTAATAGCAGATTTTTTAGAGAAGCTCGAAGTAAACCATGTAGTTACTATTAATT
TACATTCCGAAAAATAG

Upstream 100 bases:

>100_bases
GTAGAAATTCAAGAATCGTTTCATAATGAAGATGTAATCATCATACAATCCACATCAAAGCCCGTTAATGATCGCTTAAT
TGAGCTGTTTTTGCTAGTAG

Downstream 100 bases:

>100_bases
AGAAATTTTTTAATATTCCTGTTTCTAATCTTGAACCTATAAATTTATATATCCCATTTTTAAGAACTTATAGCAATTTC
GTTATAGTTGTACCTGATAA

Product: ribose-phosphate pyrophosphokinase

Products: AMP; H+; 5-Phospho-alpha-D-ribose 1-diphosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 58; Mature: 58

Protein sequence:

>58_residues
MQQTQEAASRIILVMPYFSYARQDSINSQNIIPAKLIADFLEKLEVNHVVTINLHSEK

Sequences:

>Translated_58_residues
MQQTQEAASRIILVMPYFSYARQDSINSQNIIPAKLIADFLEKLEVNHVVTINLHSEK
>Mature_58_residues
MQQTQEAASRIILVMPYFSYARQDSINSQNIIPAKLIADFLEKLEVNHVVTINLHSEK

Specific function: Utilized by both the de novo and the salvage pathways by which endogenously formed or exogenously added pyrimidine, purine, or pyridine bases are converted to the corresponding ribonucleoside monophosphates. [C]

COG id: COG0462

COG function: function code FE; Phosphoribosylpyrophosphate synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: 2.7.6.1 [C]

Molecular weight: Translated: 6658; Mature: 6658

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQQTQEAASRIILVMPYFSYARQDSINSQNIIPAKLIADFLEKLEVNHVVTINLHSEK
CCCCHHHHCEEEEEECCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC
>Mature Secondary Structure
MQQTQEAASRIILVMPYFSYARQDSINSQNIIPAKLIADFLEKLEVNHVVTINLHSEK
CCCCHHHHCEEEEEECCCHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; alpha-D-Ribose 5-phosphate [C]

Specific reaction: ATP + alpha-D-Ribose 5-phosphate <==> AMP + H+ + 5-Phospho-alpha-D-ribose 1-diphosphate [C]

General reaction: Diphosphate transfer [C]

Inhibitor: ADP [C]

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA