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The map label for this gene is gcp

Identifier: 157825262

GI number: 157825262

Start: 127170

End: 128330

Strand: Reverse

Name: gcp

Synonym: A1C_00705

Alternate gene names: 157825262

Gene position: 128330-127170 (Counterclockwise)

Preceding gene: 157825263

Following gene: 157825261

Centisome position: 10.42

GC content: 34.28

Gene sequence:

>1161_bases
ATGATAAAAATTTTAGGTATAGAATCAAGCTGTGATGATACAGCTGTTTCTATAATCACCGAAAATCGAGAAATCTTATC
TAATATAATCATTTCGCAAAATACAGAACATGCAGTTTTTGGAGGGGTAGTACCTGAAATTGCTGCACGTTCTCACTTAT
CGAATTTAGATAAAGCATTAACAAATGTTTTAAAAGAGAGCAACACTAAATTAATAGAAATTAGTGCAATTGCTGCAACT
TCCGGTCCTGGCTTAATCGGCGGTGTTATAGTCGGTTCAATGTTTGCAAGATCGCTAAGCAGTACTTTAAAAAAACCATT
TATTGCAATTAATCATTTAGAAGGTCATGCCTTAACCGCAAGGCTAACTGATAATATCCCTTATCCTTATCTACTCTTGT
TAGCTTCGGGTGGACATTGCCAATTTGTAGCGGTCCTAGGGCTTGGAAAATATAAAATATTAGGATCTACTATAGATGAT
GCCGTAGGTGAAACCTTTGACAAAGTAGCAAAAATGCTAAACTTAGCATTTCCTGGCGGACCTGAAATTGAGCAAAAAGC
AAAACTTGGCGATCCTCATAAATATAAATTTCCAAAACCTATAATTAACAGCGGTAATTGCAATATGTCCTTTTCAGGGC
TTAAAACTGCCGTGCGTACTTTAATAATGAATTTGCAAGAAATTAATTATAACGAATGTAATCATTTAGAAAGCGTCAGA
CAAGATGAAGTTCAGGAAGAGTTTGCACAGCGTACAAAAGTACATGAGCACAGGCGAAAACTGCAAAATTCGCTTGTATC
AAGCTTTCTAAATGATTCTGTAATTAATGATATAGCGGCAAGTTTTCAGTTCACCATAGGAGAAATTCTAAGTAGTAAGG
TACAGGATGCTATTAGAGCATATGAACAAATAACAAATAATTTTGATAAGAAGAATATAATTATTGCCGGCGGTGTTGCT
GCTAATAAATATTTACAAGAAATATTAAGTAATTGTGCTAAAACATATGGTTATCAGCTTATTTATCCACCTATCCATTT
ATGTACCGATAATGCTGCAATGATTGCATATGCAGGGCTTGAGCGTTACAATAATAAGTTATTTACTCCTTTGAATTTCT
GTCCAAAAGCTAGATGGAGTTTAGAGGATATTAGTAAATAA

Upstream 100 bases:

>100_bases
TAGCAATGACGGATAAGCTGCTCCACACAACAATACATTTTTGTAATGATACAAACTATCATTTTTTACTTAACAACGTC
TCTAATTAGTTTCAATTTGA

Downstream 100 bases:

>100_bases
ATTTTAATATTGACACTTCTTAATTTAGTAGTATGATAGATTATTATCATGTTTCATGGTAATAATCTACATAAAAAAGA
GGTAAGTTTATGAGCAATAA

Product: putative DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDKALTNVLKESNTKLIEISAIAAT
SGPGLIGGVIVGSMFARSLSSTLKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDD
AVGETFDKVAKMLNLAFPGGPEIEQKAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMNLQEINYNECNHLESVR
QDEVQEEFAQRTKVHEHRRKLQNSLVSSFLNDSVINDIAASFQFTIGEILSSKVQDAIRAYEQITNNFDKKNIIIAGGVA
ANKYLQEILSNCAKTYGYQLIYPPIHLCTDNAAMIAYAGLERYNNKLFTPLNFCPKARWSLEDISK

Sequences:

>Translated_386_residues
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDKALTNVLKESNTKLIEISAIAAT
SGPGLIGGVIVGSMFARSLSSTLKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDD
AVGETFDKVAKMLNLAFPGGPEIEQKAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMNLQEINYNECNHLESVR
QDEVQEEFAQRTKVHEHRRKLQNSLVSSFLNDSVINDIAASFQFTIGEILSSKVQDAIRAYEQITNNFDKKNIIIAGGVA
ANKYLQEILSNCAKTYGYQLIYPPIHLCTDNAAMIAYAGLERYNNKLFTPLNFCPKARWSLEDISK
>Mature_386_residues
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDKALTNVLKESNTKLIEISAIAAT
SGPGLIGGVIVGSMFARSLSSTLKKPFIAINHLEGHALTARLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDD
AVGETFDKVAKMLNLAFPGGPEIEQKAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMNLQEINYNECNHLESVR
QDEVQEEFAQRTKVHEHRRKLQNSLVSSFLNDSVINDIAASFQFTIGEILSSKVQDAIRAYEQITNNFDKKNIIIAGGVA
ANKYLQEILSNCAKTYGYQLIYPPIHLCTDNAAMIAYAGLERYNNKLFTPLNFCPKARWSLEDISK

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family

Homologues:

Organism=Homo sapiens, GI116812636, Length=376, Percent_Identity=34.3085106382979, Blast_Score=196, Evalue=3e-50,
Organism=Homo sapiens, GI8923380, Length=374, Percent_Identity=26.4705882352941, Blast_Score=108, Evalue=7e-24,
Organism=Escherichia coli, GI1789445, Length=384, Percent_Identity=35.6770833333333, Blast_Score=248, Evalue=5e-67,
Organism=Caenorhabditis elegans, GI17557464, Length=371, Percent_Identity=29.1105121293801, Blast_Score=146, Evalue=2e-35,
Organism=Caenorhabditis elegans, GI71995670, Length=371, Percent_Identity=30.4582210242588, Blast_Score=111, Evalue=6e-25,
Organism=Saccharomyces cerevisiae, GI6320099, Length=405, Percent_Identity=28.641975308642, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6322891, Length=379, Percent_Identity=25.8575197889182, Blast_Score=87, Evalue=6e-18,
Organism=Drosophila melanogaster, GI20129063, Length=373, Percent_Identity=32.7077747989276, Blast_Score=211, Evalue=9e-55,
Organism=Drosophila melanogaster, GI21357207, Length=373, Percent_Identity=28.4182305630027, Blast_Score=119, Evalue=4e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GCP_RICAH (A8GM49)

Other databases:

- EMBL:   CP000847
- RefSeq:   YP_001492982.1
- STRING:   A8GM49
- MEROPS:   M22.001
- GeneID:   5645476
- GenomeReviews:   CP000847_GR
- KEGG:   rak:A1C_00705
- NMPDR:   fig|293614.3.peg.129
- eggNOG:   COG0533
- HOGENOM:   HBG304663
- OMA:   RNCNFSF
- ProtClustDB:   PRK09604
- BioCyc:   RAKA293614:A1C_00705-MONOMER
- GO:   GO:0006508
- HAMAP:   MF_01445
- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861
- InterPro:   IPR022437
- PANTHER:   PTHR11735
- PRINTS:   PR00789
- TIGRFAMs:   TIGR03723
- TIGRFAMs:   TIGR00329
- TIGRFAMs:   TIGR03775

Pfam domain/function: PF00814 Peptidase_M22

EC number: =3.4.24.57

Molecular weight: Translated: 42389; Mature: 42389

Theoretical pI: Translated: 7.55; Mature: 7.55

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDKAL
CEEEEECCCCCCCHHHHEEECCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
TNVLKESNTKLIEISAIAATSGPGLIGGVIVGSMFARSLSSTLKKPFIAINHLEGHALTA
HHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEE
RLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAVGETFDKVAKMLNLAFPGG
EECCCCCCCEEEEEECCCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCC
PEIEQKAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMNLQEINYNECNHLESVR
CCHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QDEVQEEFAQRTKVHEHRRKLQNSLVSSFLNDSVINDIAASFQFTIGEILSSKVQDAIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YEQITNNFDKKNIIIAGGVAANKYLQEILSNCAKTYGYQLIYPPIHLCTDNAAMIAYAGL
HHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEECCCCEEECCCCHHHHHHHH
ERYNNKLFTPLNFCPKARWSLEDISK
HHHCCCCCCCCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MIKILGIESSCDDTAVSIITENREILSNIIISQNTEHAVFGGVVPEIAARSHLSNLDKAL
CEEEEECCCCCCCHHHHEEECCHHHHHHHHHCCCCCCHHHCCHHHHHHHHHHHHHHHHHH
TNVLKESNTKLIEISAIAATSGPGLIGGVIVGSMFARSLSSTLKKPFIAINHLEGHALTA
HHHHHHCCCCEEEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEEE
RLTDNIPYPYLLLLASGGHCQFVAVLGLGKYKILGSTIDDAVGETFDKVAKMLNLAFPGG
EECCCCCCCEEEEEECCCCEEEEEEECCCCCEEECCHHHHHHHHHHHHHHHHHHHCCCCC
PEIEQKAKLGDPHKYKFPKPIINSGNCNMSFSGLKTAVRTLIMNLQEINYNECNHLESVR
CCHHHHHCCCCCCCCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHCCCCHHHHHHHHH
QDEVQEEFAQRTKVHEHRRKLQNSLVSSFLNDSVINDIAASFQFTIGEILSSKVQDAIRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YEQITNNFDKKNIIIAGGVAANKYLQEILSNCAKTYGYQLIYPPIHLCTDNAAMIAYAGL
HHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHCCEEECCCCEEECCCCHHHHHHHH
ERYNNKLFTPLNFCPKARWSLEDISK
HHHCCCCCCCCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA