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The map label for this gene is tsf [H]

Identifier: 157825246

GI number: 157825246

Start: 115646

End: 116575

Strand: Direct

Name: tsf [H]

Synonym: A1C_00625

Alternate gene names: 157825246

Gene position: 115646-116575 (Clockwise)

Preceding gene: 157825245

Following gene: 157825252

Centisome position: 9.39

GC content: 35.91

Gene sequence:

>930_bases
ATGAGTGAAATAAATATAAGTGCTGCAGCGGTTAAAGAATTAAGAGAAAAAACAGGTGCAGGTATGATGGACTGCAAAAA
AGCATTAATAGAAACCAGCGGTAATTTTGAAGAAGCTATAGATTTTTTGCGTAAGAAAGGCTTAGCTGTAGCAGCAAAAA
AAGCCGGACGTATTGCTGCTGAAGGTTTAACGGCTGTAAAAGTTGATGGGCTTACCGGAGTGGTGGTTGAAGTCAATTCC
GAAACGGATTTTGTTGCTAGAAATGCGCGATTTCAGGATTTAGCTAAGGATATTGCAAACCTTGCAGTAATTGCAAAAAA
TATAGACACGCTAAAAACATCTAAAATGCAAAGCGGTAAATCAGTTGAAGAAGAGATTATAGCAAATATCGCGACAATAG
GTGAAAATTTAGCATTACGTCGTATGGATATATTAGAGATATCCGAAGGAGCAATCGGTTCGTACGTACATAATGAAGTT
GTACCGAATCTAGGCAAAATTTCCGTATTAGTAGGTCTTGTGTCTAATGCAAAAGATAAAGCAAAGCTAGAAGCTTTAGC
TAAACAAATTGCTGTTCATGTAGCAGGAAATAACCCACAAAGTATAGATGATTCAAGCTTGGATCAAGCACTCGTAGAGC
GTGAGAGAAAAGTATTTTTTGAGAAATCTAAAGAAGAAGGAAAGCCTGATAATATTATAGAAAAAATGGTAGAGGGTAGA
ATACGTAAATTCTTCTCTGAAGTTGTATTGCTTCAGCAAAATTTTTTATTTGATCCTAAACTTACTGTTGCGGAAGTAAT
TAAAAATGCTGAACAAGAACTCGGTGCAGAAATTAAAATCGCCAAATTTATTAGATACGAACTTGGTGAAGGTATAGAAC
ACGAAGAAAAAAACTTTGTCGATGAAGTAGCTGCTATTACGCGAAGTTAA

Upstream 100 bases:

>100_bases
CGCTTTCGCGGGAATGACATAAAGAGCGATTTCCATAGTTCAGACGATTAGGTATATACAAACCACAAGCCAAATATAAT
AATTAAGGAGAAAGTAAGGT

Downstream 100 bases:

>100_bases
GTGGTTTGTTTCATAGATTCAATGTCATTCCCACTTGGATACCAAGTCATCATTGCGAGCATGCGTTGTTGTGCAGACAC
AATTCCATCCTATCATCCCG

Product: elongation factor Ts

Products: NA

Alternate protein names: EF-Ts [H]

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MSEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAVAAKKAGRIAAEGLTAVKVDGLTGVVVEVNS
ETDFVARNARFQDLAKDIANLAVIAKNIDTLKTSKMQSGKSVEEEIIANIATIGENLALRRMDILEISEGAIGSYVHNEV
VPNLGKISVLVGLVSNAKDKAKLEALAKQIAVHVAGNNPQSIDDSSLDQALVERERKVFFEKSKEEGKPDNIIEKMVEGR
IRKFFSEVVLLQQNFLFDPKLTVAEVIKNAEQELGAEIKIAKFIRYELGEGIEHEEKNFVDEVAAITRS

Sequences:

>Translated_309_residues
MSEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAVAAKKAGRIAAEGLTAVKVDGLTGVVVEVNS
ETDFVARNARFQDLAKDIANLAVIAKNIDTLKTSKMQSGKSVEEEIIANIATIGENLALRRMDILEISEGAIGSYVHNEV
VPNLGKISVLVGLVSNAKDKAKLEALAKQIAVHVAGNNPQSIDDSSLDQALVERERKVFFEKSKEEGKPDNIIEKMVEGR
IRKFFSEVVLLQQNFLFDPKLTVAEVIKNAEQELGAEIKIAKFIRYELGEGIEHEEKNFVDEVAAITRS
>Mature_308_residues
SEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAVAAKKAGRIAAEGLTAVKVDGLTGVVVEVNSE
TDFVARNARFQDLAKDIANLAVIAKNIDTLKTSKMQSGKSVEEEIIANIATIGENLALRRMDILEISEGAIGSYVHNEVV
PNLGKISVLVGLVSNAKDKAKLEALAKQIAVHVAGNNPQSIDDSSLDQALVERERKVFFEKSKEEGKPDNIIEKMVEGRI
RKFFSEVVLLQQNFLFDPKLTVAEVIKNAEQELGAEIKIAKFIRYELGEGIEHEEKNFVDEVAAITRS

Specific function: Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome [H]

COG id: COG0264

COG function: function code J; Translation elongation factor Ts

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EF-Ts family [H]

Homologues:

Organism=Homo sapiens, GI171846268, Length=304, Percent_Identity=29.2763157894737, Blast_Score=104, Evalue=9e-23,
Organism=Homo sapiens, GI291084500, Length=323, Percent_Identity=27.5541795665635, Blast_Score=99, Evalue=4e-21,
Organism=Homo sapiens, GI291084498, Length=91, Percent_Identity=45.0549450549451, Blast_Score=75, Evalue=1e-13,
Organism=Homo sapiens, GI291084502, Length=91, Percent_Identity=45.0549450549451, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1786366, Length=305, Percent_Identity=43.2786885245902, Blast_Score=217, Evalue=7e-58,
Organism=Caenorhabditis elegans, GI17561440, Length=311, Percent_Identity=29.903536977492, Blast_Score=113, Evalue=1e-25,
Organism=Drosophila melanogaster, GI19921466, Length=313, Percent_Identity=25.5591054313099, Blast_Score=80, Evalue=2e-15,

Paralogues:

None

Copy number: 2670 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1100 Molecules/Cell In: Stationary-Phase, Rich-Media (Based on E. coli). 4173 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 14563 Molecules/Cell In: Growth Phase, Gluco

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001816
- InterPro:   IPR014039
- InterPro:   IPR018101
- InterPro:   IPR009060
- InterPro:   IPR000449 [H]

Pfam domain/function: PF00889 EF_TS; PF00627 UBA [H]

EC number: NA

Molecular weight: Translated: 33738; Mature: 33607

Theoretical pI: Translated: 5.10; Mature: 5.10

Prosite motif: PS01126 EF_TS_1 ; PS01127 EF_TS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAVAAKKAGRIAA
CCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCCHHH
EGLTAVKVDGLTGVVVEVNSETDFVARNARFQDLAKDIANLAVIAKNIDTLKTSKMQSGK
CCCCEEEECCCEEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVEEEIIANIATIGENLALRRMDILEISEGAIGSYVHNEVVPNLGKISVLVGLVSNAKDK
CHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHH
AKLEALAKQIAVHVAGNNPQSIDDSSLDQALVERERKVFFEKSKEEGKPDNIIEKMVEGR
HHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IRKFFSEVVLLQQNFLFDPKLTVAEVIKNAEQELGAEIKIAKFIRYELGEGIEHEEKNFV
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHH
DEVAAITRS
HHHHHHHCC
>Mature Secondary Structure 
SEINISAAAVKELREKTGAGMMDCKKALIETSGNFEEAIDFLRKKGLAVAAKKAGRIAA
CCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCHHHHHHHHHHCCCHHHHHHCCCHHH
EGLTAVKVDGLTGVVVEVNSETDFVARNARFQDLAKDIANLAVIAKNIDTLKTSKMQSGK
CCCCEEEECCCEEEEEEECCCCCHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
SVEEEIIANIATIGENLALRRMDILEISEGAIGSYVHNEVVPNLGKISVLVGLVSNAKDK
CHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCHHH
AKLEALAKQIAVHVAGNNPQSIDDSSLDQALVERERKVFFEKSKEEGKPDNIIEKMVEGR
HHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHH
IRKFFSEVVLLQQNFLFDPKLTVAEVIKNAEQELGAEIKIAKFIRYELGEGIEHEEKNFV
HHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHH
DEVAAITRS
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA