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The map label for this gene is cysS [H]

Identifier: 157825244

GI number: 157825244

Start: 112799

End: 114178

Strand: Direct

Name: cysS [H]

Synonym: A1C_00615

Alternate gene names: 157825244

Gene position: 112799-114178 (Clockwise)

Preceding gene: 157825241

Following gene: 157825245

Centisome position: 9.16

GC content: 33.19

Gene sequence:

>1380_bases
ATGCAAATTCAATTGCACTTGTATAACACTCTTAGCCGTACTAAAGAGGTTTTTAATCCTCAAGATCAAGCTAACATAAA
AATGTATGTGTGTGGACCGACTGTTTATGATAATCCTCATATAGGCAATAGTAGATCGGTAGTAGTATATGATTTACTTT
ATCGTATAGTTATAAAAATATTCGGCAGTAGAGCAGTAAAATATGTACGCAATATTACCGATGTTGACGATAAAATTATT
GATAGAGCTGAACTACTTGGCATTACTATTAATGAGTTGACTGATAAAGTTACACAAGAGTTTCATACAAATATGGCATA
TTTAGGTTGCATGCTACCGAATATTGAGCCGAAAGCTACAGAGCATATTGATGTAATGATCGAAATAATAGAGCGCTTAA
TAGCAAAAGATCATGCATATATTACAGATAATCATGTTTATTTTGATGTTTTATCAGCTCCAAATTATACGGAATTATCT
AACCGAAATTTAGAAGAAATGTTTGAGGGAGTGCGTATAGAAAAGAGCAAAACCAAAAATCATCCACAGGATTTTGTATT
ATGGAAACCGGCAAAGCCAAATGAATCCACAAATATGAATTTTGAAAGTCCTTGGGGATTTGGTCGCCCTGGATGGCACA
TTGAATGTTCAGCCATGAGCTATAAATATTTAGGTGAGAATTTTGATATTCACGGTGGCGGAGCAGATTTAGTCTTTCCG
CATCATACTAATGAAATTGCACAAAGTAGATGTGCTTTTCCGGATTCTACCTATGCTAAATATTGGGTACATAATGGCTT
TCTAACGGTGAATGGTGAGAAAATGAGTAAATCTCTCGGTAATTTTATTACAGTAAGGGATTTAATGGATAAGGACATTT
CAGGAGAGGTAGTAAGATTATTCTTATTAAGTAGCCATTATAGGCGTCCACTTGATTATAATGATAAAGCTATAGAAGAT
GCTAAGAAGACTTTAGATTATTGGTATAGAGCCATAGAAAATATTAATGTACAAAAAATAGATTTACCTCACAATTTCAT
GCAAAGCTTACTTGATGACATGAATACGCCGCTTGCCGTTAAAATAATTAATGACTATGCTAAAGGTGTTTTTATTGCTA
AAACTGAAAAAGAAAGACAGCTTAATGCCTCTGTTATTATTACTTGTGCTAATTTTATTGGTTTAATGAATCAGACTCCC
CATGAGTGGTTTAATAGCGGTGTAGATTCACTCTATATAAATGAGCTTGTAAATAAGCGTTTGGAAGCAAAAAAACAAAA
AAATTGGTTATTAGCCGATCAAATTCGTAACCAGTTATTAGAGGGAAAAATAATTCTAGAAGATAAATCTGATGGTACCA
CTATTTGGCGAAAAGAATAA

Upstream 100 bases:

>100_bases
AATTATTAATTATTAGTTTTGTTTAACTAATAGATTTTTAAACTAAAATGTGTTTAATACATCACATACTAATTGCATCT
CAATTTTTGGTAAATAAAAT

Downstream 100 bases:

>100_bases
AAGCTTGTAAATTATGCAATATACTTATATAGTTTGCAGGCCTATTGTAGAACGTCATTGCGAGGAAATTGTGTAAAATA
ATTGACGCAGCAATCTCAGG

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MQIQLHLYNTLSRTKEVFNPQDQANIKMYVCGPTVYDNPHIGNSRSVVVYDLLYRIVIKIFGSRAVKYVRNITDVDDKII
DRAELLGITINELTDKVTQEFHTNMAYLGCMLPNIEPKATEHIDVMIEIIERLIAKDHAYITDNHVYFDVLSAPNYTELS
NRNLEEMFEGVRIEKSKTKNHPQDFVLWKPAKPNESTNMNFESPWGFGRPGWHIECSAMSYKYLGENFDIHGGGADLVFP
HHTNEIAQSRCAFPDSTYAKYWVHNGFLTVNGEKMSKSLGNFITVRDLMDKDISGEVVRLFLLSSHYRRPLDYNDKAIED
AKKTLDYWYRAIENINVQKIDLPHNFMQSLLDDMNTPLAVKIINDYAKGVFIAKTEKERQLNASVIITCANFIGLMNQTP
HEWFNSGVDSLYINELVNKRLEAKKQKNWLLADQIRNQLLEGKIILEDKSDGTTIWRKE

Sequences:

>Translated_459_residues
MQIQLHLYNTLSRTKEVFNPQDQANIKMYVCGPTVYDNPHIGNSRSVVVYDLLYRIVIKIFGSRAVKYVRNITDVDDKII
DRAELLGITINELTDKVTQEFHTNMAYLGCMLPNIEPKATEHIDVMIEIIERLIAKDHAYITDNHVYFDVLSAPNYTELS
NRNLEEMFEGVRIEKSKTKNHPQDFVLWKPAKPNESTNMNFESPWGFGRPGWHIECSAMSYKYLGENFDIHGGGADLVFP
HHTNEIAQSRCAFPDSTYAKYWVHNGFLTVNGEKMSKSLGNFITVRDLMDKDISGEVVRLFLLSSHYRRPLDYNDKAIED
AKKTLDYWYRAIENINVQKIDLPHNFMQSLLDDMNTPLAVKIINDYAKGVFIAKTEKERQLNASVIITCANFIGLMNQTP
HEWFNSGVDSLYINELVNKRLEAKKQKNWLLADQIRNQLLEGKIILEDKSDGTTIWRKE
>Mature_459_residues
MQIQLHLYNTLSRTKEVFNPQDQANIKMYVCGPTVYDNPHIGNSRSVVVYDLLYRIVIKIFGSRAVKYVRNITDVDDKII
DRAELLGITINELTDKVTQEFHTNMAYLGCMLPNIEPKATEHIDVMIEIIERLIAKDHAYITDNHVYFDVLSAPNYTELS
NRNLEEMFEGVRIEKSKTKNHPQDFVLWKPAKPNESTNMNFESPWGFGRPGWHIECSAMSYKYLGENFDIHGGGADLVFP
HHTNEIAQSRCAFPDSTYAKYWVHNGFLTVNGEKMSKSLGNFITVRDLMDKDISGEVVRLFLLSSHYRRPLDYNDKAIED
AKKTLDYWYRAIENINVQKIDLPHNFMQSLLDDMNTPLAVKIINDYAKGVFIAKTEKERQLNASVIITCANFIGLMNQTP
HEWFNSGVDSLYINELVNKRLEAKKQKNWLLADQIRNQLLEGKIILEDKSDGTTIWRKE

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=319, Percent_Identity=42.3197492163009, Blast_Score=236, Evalue=5e-62,
Organism=Homo sapiens, GI303304987, Length=279, Percent_Identity=34.0501792114695, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI10835051, Length=263, Percent_Identity=34.9809885931559, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI62240992, Length=279, Percent_Identity=34.0501792114695, Blast_Score=176, Evalue=4e-44,
Organism=Homo sapiens, GI21269877, Length=279, Percent_Identity=34.0501792114695, Blast_Score=176, Evalue=4e-44,
Organism=Escherichia coli, GI1786737, Length=470, Percent_Identity=44.2553191489362, Blast_Score=365, Evalue=1e-102,
Organism=Caenorhabditis elegans, GI17509797, Length=251, Percent_Identity=36.2549800796813, Blast_Score=153, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI17509795, Length=251, Percent_Identity=36.2549800796813, Blast_Score=153, Evalue=2e-37,
Organism=Saccharomyces cerevisiae, GI6324082, Length=338, Percent_Identity=32.2485207100592, Blast_Score=165, Evalue=2e-41,
Organism=Drosophila melanogaster, GI19922218, Length=504, Percent_Identity=32.9365079365079, Blast_Score=229, Evalue=4e-60,
Organism=Drosophila melanogaster, GI19922364, Length=237, Percent_Identity=38.8185654008439, Blast_Score=171, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 53039; Mature: 53039

Theoretical pI: Translated: 6.46; Mature: 6.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQIQLHLYNTLSRTKEVFNPQDQANIKMYVCGPTVYDNPHIGNSRSVVVYDLLYRIVIKI
CEEEEEEHHHHHHHHHHCCCCCCCCEEEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHH
FGSRAVKYVRNITDVDDKIIDRAELLGITINELTDKVTQEFHTNMAYLGCMLPNIEPKAT
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHH
EHIDVMIEIIERLIAKDHAYITDNHVYFDVLSAPNYTELSNRNLEEMFEGVRIEKSKTKN
HHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCCCCCCHHHHHCCCEEECHHCCC
HPQDFVLWKPAKPNESTNMNFESPWGFGRPGWHIECSAMSYKYLGENFDIHGGGADLVFP
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECEEEECCCCCEEECCCCCEEECC
HHTNEIAQSRCAFPDSTYAKYWVHNGFLTVNGEKMSKSLGNFITVRDLMDKDISGEVVRL
CCCHHHHHHHCCCCCCCCCEEEEECCEEEECHHHHHHHHCCEEEEHHHHCCCCCHHHHHH
FLLSSHYRRPLDYNDKAIEDAKKTLDYWYRAIENINVQKIDLPHNFMQSLLDDMNTPLAV
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCEEE
KIINDYAKGVFIAKTEKERQLNASVIITCANFIGLMNQTPHEWFNSGVDSLYINELVNKR
EEEHHHHCCEEEEECCHHHHCCCCEEEEHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHH
LEAKKQKNWLLADQIRNQLLEGKIILEDKSDGTTIWRKE
HHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCEEEECC
>Mature Secondary Structure
MQIQLHLYNTLSRTKEVFNPQDQANIKMYVCGPTVYDNPHIGNSRSVVVYDLLYRIVIKI
CEEEEEEHHHHHHHHHHCCCCCCCCEEEEEECCEECCCCCCCCCCCCHHHHHHHHHHHHH
FGSRAVKYVRNITDVDDKIIDRAELLGITINELTDKVTQEFHTNMAYLGCMLPNIEPKAT
HHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHCCCCCCCCHH
EHIDVMIEIIERLIAKDHAYITDNHVYFDVLSAPNYTELSNRNLEEMFEGVRIEKSKTKN
HHHHHHHHHHHHHHHCCCCEEECCEEEEEEECCCCCCCCCCCCHHHHHCCCEEECHHCCC
HPQDFVLWKPAKPNESTNMNFESPWGFGRPGWHIECSAMSYKYLGENFDIHGGGADLVFP
CCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCEEEEECEEEECCCCCEEECCCCCEEECC
HHTNEIAQSRCAFPDSTYAKYWVHNGFLTVNGEKMSKSLGNFITVRDLMDKDISGEVVRL
CCCHHHHHHHCCCCCCCCCEEEEECCEEEECHHHHHHHHCCEEEEHHHHCCCCCHHHHHH
FLLSSHYRRPLDYNDKAIEDAKKTLDYWYRAIENINVQKIDLPHNFMQSLLDDMNTPLAV
HHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCEEEEECCHHHHHHHHHHCCCCEEE
KIINDYAKGVFIAKTEKERQLNASVIITCANFIGLMNQTPHEWFNSGVDSLYINELVNKR
EEEHHHHCCEEEEECCHHHHCCCCEEEEHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHHH
LEAKKQKNWLLADQIRNQLLEGKIILEDKSDGTTIWRKE
HHHHHHCCCCHHHHHHHHHHCCEEEEEECCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA