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The map label for this gene is argS [H]

Identifier: 157825222

GI number: 157825222

Start: 82718

End: 84448

Strand: Direct

Name: argS [H]

Synonym: A1C_00505

Alternate gene names: 157825222

Gene position: 82718-84448 (Clockwise)

Preceding gene: 157825221

Following gene: 157825223

Centisome position: 6.72

GC content: 33.45

Gene sequence:

>1731_bases
ATGAATATATTTAATAAATTAAAACAAGATATAATTGCGGCAAGCAGGCAATTATATAATAATCAAGAAATAGCAAATAA
TGCTACTATTGAAACTCCAAAAGATAATTTTAACGGCGATTTATCCAGTAATATTGCAATGATTATTGCTGCTAAAGAAA
ATATTTCGCCTCGGGAAGTTGCTTTAAAGTTTAAAGAAATCCTTATAACATTACCTTATATTGCAAGTATAGAAATAGCA
GGACCCGGCTTTATTAACTTTACTATAAAAGCCGAAACTTGGCAGATAGCAATTAAAGATATTCTACAGCACGAAGAAAA
GTTTTGTGAAATTGATATAGATAAAAGCAGAAATATTAACATCGAGTATGTTTCGGCAAATCCCACCGGTCCAATGCATA
TAGGGCATGCTAGGGGTGCGGTATATGGTGATGTGTTAGCTAGAATTTTGCAAAAAGTAGGTTATTTCGTTACAAAAGAA
TATTATGTTAATGATGCAGGTTCGCAAATAAATGATTTAGTTAGTACGGTATTATTACGTTATAGAGAAGCGTTGGGCGA
GACAATTACTATCCCTGACGGTTTGTACCCAGGCGAGTATTTAATTCCGCTTGGGCAAATTTTGGCGGAAGAATACGGTA
ATAAATTATTAATGATGGATGAAGAGGAAAGATTCAAAATAGTGAAAAATTTTGCCGTAGAAAAGATGCTTGATTTAAAT
AGAAAAGATCTAGCAGACCTTGGTATTAAACATGATATATTTTTTTCTGAACAGTCATTGCATGATAAATGCGCAATAGA
GGAAACGGTGAAATTACTTACCGGTATGGGGCTGATTTATGAAGGAATACTCCCACCTCCTAAAGGGAAAGTTCACGATG
AATGGGATAACAGAGTTCAAAAGTTATTTAAATCTACTAACTATGGTGATAGTCAGGATCGTCCTATAGAAAAAGCTGAC
GGAAGTTGGTCTTATTTTGCTTCCGATCTTGCATATGCTAAGGATAAAATAGATAGGGGAGTGAGCCACCTAATTTATGT
ACTTGGTGCTGATCATAGCGGGTATGTTAAAAGAATTGAGGCAATAGTTAAGGCTCTAGGCAAAGAGCAAGTTAAAGTAG
ACGTTAAAATCTGTCAATTGGTTAATTTTGTTGAAAACGGTGTGCCGGTTAAAATGTCAAAACGTCTTGGAAGCTTTGCT
AGTGTACAAGACGTAAATCATGAGGTAGGGAAAGATATCATAAGATTTATGATGTTAACAAGGCAAAATGATAAGCCTCT
TGATTTTGATTTAGTAAAAGTGAAAGAACAATCAAGAGAAAATCCCATTTTTTATGTACAATATGCACATGTAAGAACAA
TATCAATTTTATCAAAAGCTAGAGAATTAATGCCTGAATCTTATAATAACTTTGAAGCCTGCAAGTATGATTTATCTTTA
TTATCCTCAGAAGAAGAAATTGCGATCATAAAACTTTTAGCTAGTTGGACAAAAACATTAGAAACATCTGCAAAATATTT
TGAACCGCACCGCATTGCATTTTATTTAATAAATTTAGCTTCAAAATTTCATTCTATGTGGAATTTTGGTAAAGAACATA
GCGACTATAGATTTATAATTGAGAGCAATAAAGAATTAACTACTGCTCGTCTTGCTCTTGCAACTGCAATACAGAAAGTT
ATAGCTAGTGGTCTTGAAGTGATAGGTGTAGAACCTATGGATAGGATGTAA

Upstream 100 bases:

>100_bases
GTTATTGCCGATTATATAGCAGGTATGACCGACCGTTTTGCTATTCAAGAATATAATCAGCTTTGTTCACTGAATTTTAA
TAATATCTTAAAACTTAATT

Downstream 100 bases:

>100_bases
TATGAGGCAACTAATCCTGTCATCCAGTGGCTTGAGCATGTGATCCAGCATAAAGCGAGATAAATCAAGCTTTTTGTATT
CGTATTTTTTTACTGGACCC

Product: arginyl-tRNA synthetase

Products: NA

Alternate protein names: Arginine--tRNA ligase; ArgRS [H]

Number of amino acids: Translated: 576; Mature: 576

Protein sequence:

>576_residues
MNIFNKLKQDIIAASRQLYNNQEIANNATIETPKDNFNGDLSSNIAMIIAAKENISPREVALKFKEILITLPYIASIEIA
GPGFINFTIKAETWQIAIKDILQHEEKFCEIDIDKSRNINIEYVSANPTGPMHIGHARGAVYGDVLARILQKVGYFVTKE
YYVNDAGSQINDLVSTVLLRYREALGETITIPDGLYPGEYLIPLGQILAEEYGNKLLMMDEEERFKIVKNFAVEKMLDLN
RKDLADLGIKHDIFFSEQSLHDKCAIEETVKLLTGMGLIYEGILPPPKGKVHDEWDNRVQKLFKSTNYGDSQDRPIEKAD
GSWSYFASDLAYAKDKIDRGVSHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFA
SVQDVNHEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKARELMPESYNNFEACKYDLSL
LSSEEEIAIIKLLASWTKTLETSAKYFEPHRIAFYLINLASKFHSMWNFGKEHSDYRFIIESNKELTTARLALATAIQKV
IASGLEVIGVEPMDRM

Sequences:

>Translated_576_residues
MNIFNKLKQDIIAASRQLYNNQEIANNATIETPKDNFNGDLSSNIAMIIAAKENISPREVALKFKEILITLPYIASIEIA
GPGFINFTIKAETWQIAIKDILQHEEKFCEIDIDKSRNINIEYVSANPTGPMHIGHARGAVYGDVLARILQKVGYFVTKE
YYVNDAGSQINDLVSTVLLRYREALGETITIPDGLYPGEYLIPLGQILAEEYGNKLLMMDEEERFKIVKNFAVEKMLDLN
RKDLADLGIKHDIFFSEQSLHDKCAIEETVKLLTGMGLIYEGILPPPKGKVHDEWDNRVQKLFKSTNYGDSQDRPIEKAD
GSWSYFASDLAYAKDKIDRGVSHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFA
SVQDVNHEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKARELMPESYNNFEACKYDLSL
LSSEEEIAIIKLLASWTKTLETSAKYFEPHRIAFYLINLASKFHSMWNFGKEHSDYRFIIESNKELTTARLALATAIQKV
IASGLEVIGVEPMDRM
>Mature_576_residues
MNIFNKLKQDIIAASRQLYNNQEIANNATIETPKDNFNGDLSSNIAMIIAAKENISPREVALKFKEILITLPYIASIEIA
GPGFINFTIKAETWQIAIKDILQHEEKFCEIDIDKSRNINIEYVSANPTGPMHIGHARGAVYGDVLARILQKVGYFVTKE
YYVNDAGSQINDLVSTVLLRYREALGETITIPDGLYPGEYLIPLGQILAEEYGNKLLMMDEEERFKIVKNFAVEKMLDLN
RKDLADLGIKHDIFFSEQSLHDKCAIEETVKLLTGMGLIYEGILPPPKGKVHDEWDNRVQKLFKSTNYGDSQDRPIEKAD
GSWSYFASDLAYAKDKIDRGVSHLIYVLGADHSGYVKRIEAIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFA
SVQDVNHEVGKDIIRFMMLTRQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKARELMPESYNNFEACKYDLSL
LSSEEEIAIIKLLASWTKTLETSAKYFEPHRIAFYLINLASKFHSMWNFGKEHSDYRFIIESNKELTTARLALATAIQKV
IASGLEVIGVEPMDRM

Specific function: Unknown

COG id: COG0018

COG function: function code J; Arginyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI15149476, Length=639, Percent_Identity=21.9092331768388, Blast_Score=92, Evalue=1e-18,
Organism=Escherichia coli, GI1788184, Length=621, Percent_Identity=23.9935587761675, Blast_Score=104, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71985061, Length=618, Percent_Identity=24.5954692556634, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71985068, Length=565, Percent_Identity=24.6017699115044, Blast_Score=81, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6320548, Length=569, Percent_Identity=25.6590509666081, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6321883, Length=574, Percent_Identity=23.1707317073171, Blast_Score=84, Evalue=4e-17,
Organism=Drosophila melanogaster, GI18859963, Length=599, Percent_Identity=22.8714524207012, Blast_Score=85, Evalue=2e-16,

Paralogues:

None

Copy number: 789 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 800 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001412
- InterPro:   IPR001278
- InterPro:   IPR015945
- InterPro:   IPR005148
- InterPro:   IPR008909
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF03485 Arg_tRNA_synt_N; PF05746 DALR_1; PF00750 tRNA-synt_1d [H]

EC number: =6.1.1.19 [H]

Molecular weight: Translated: 65388; Mature: 65388

Theoretical pI: Translated: 6.09; Mature: 6.09

Prosite motif: PS00178 AA_TRNA_LIGASE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIFNKLKQDIIAASRQLYNNQEIANNATIETPKDNFNGDLSSNIAMIIAAKENISPREV
CCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHH
ALKFKEILITLPYIASIEIAGPGFINFTIKAETWQIAIKDILQHEEKFCEIDIDKSRNIN
HHHHHHHHHCCCCCEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHHEEEECCCCCCCE
IEYVSANPTGPMHIGHARGAVYGDVLARILQKVGYFVTKEYYVNDAGSQINDLVSTVLLR
EEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
YREALGETITIPDGLYPGEYLIPLGQILAEEYGNKLLMMDEEERFKIVKNFAVEKMLDLN
HHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCC
RKDLADLGIKHDIFFSEQSLHDKCAIEETVKLLTGMGLIYEGILPPPKGKVHDEWDNRVQ
HHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHH
KLFKSTNYGDSQDRPIEKADGSWSYFASDLAYAKDKIDRGVSHLIYVLGADHSGYVKRIE
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCHHHHHHH
AIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFASVQDVNHEVGKDIIRFMMLT
HHHHHHCCHHEEHHHHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKARELMPESYNNFEACKYDLSL
CCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LSSEEEIAIIKLLASWTKTLETSAKYFEPHRIAFYLINLASKFHSMWNFGKEHSDYRFII
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ESNKELTTARLALATAIQKVIASGLEVIGVEPMDRM
ECCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC
>Mature Secondary Structure
MNIFNKLKQDIIAASRQLYNNQEIANNATIETPKDNFNGDLSSNIAMIIAAKENISPREV
CCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHH
ALKFKEILITLPYIASIEIAGPGFINFTIKAETWQIAIKDILQHEEKFCEIDIDKSRNIN
HHHHHHHHHCCCCCEEEEECCCCEEEEEEEECHHHHHHHHHHHHHHHHEEEECCCCCCCE
IEYVSANPTGPMHIGHARGAVYGDVLARILQKVGYFVTKEYYVNDAGSQINDLVSTVLLR
EEEEECCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHH
YREALGETITIPDGLYPGEYLIPLGQILAEEYGNKLLMMDEEERFKIVKNFAVEKMLDLN
HHHHHCCEEECCCCCCCCHHHHHHHHHHHHHHCCEEEEECCHHHHHHHHHHHHHHHHCCC
RKDLADLGIKHDIFFSEQSLHDKCAIEETVKLLTGMGLIYEGILPPPKGKVHDEWDNRVQ
HHHHHHCCCCCEEEECCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCCCCCHHHHHHH
KLFKSTNYGDSQDRPIEKADGSWSYFASDLAYAKDKIDRGVSHLIYVLGADHSGYVKRIE
HHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHEEEEEECCCCHHHHHHH
AIVKALGKEQVKVDVKICQLVNFVENGVPVKMSKRLGSFASVQDVNHEVGKDIIRFMMLT
HHHHHHCCHHEEHHHHHHHHHHHHHCCCCEEEHHHCCCHHHHHHHHHHHHHHHHHHHHHH
RQNDKPLDFDLVKVKEQSRENPIFYVQYAHVRTISILSKARELMPESYNNFEACKYDLSL
CCCCCCCCHHHHHHHHHCCCCCEEEEEEHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHH
LSSEEEIAIIKLLASWTKTLETSAKYFEPHRIAFYLINLASKFHSMWNFGKEHSDYRFII
HCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEE
ESNKELTTARLALATAIQKVIASGLEVIGVEPMDRM
ECCCCHHHHHHHHHHHHHHHHHCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA