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The map label for this gene is sdhB [H]

Identifier: 157825197

GI number: 157825197

Start: 58740

End: 59525

Strand: Direct

Name: sdhB [H]

Synonym: A1C_00380

Alternate gene names: 157825197

Gene position: 58740-59525 (Clockwise)

Preceding gene: 157825196

Following gene: 157825198

Centisome position: 4.77

GC content: 35.62

Gene sequence:

>786_bases
ATGGCAGAGTTAAGATTACCGCCAAATTCAGTAGTAAAAAAAGGAAAAGAGTATAAAGAACAAGAGGAAATGTTTAAACC
TAGAAAGGTAAAAATTTATAGGTATGATCCTGATCTTGATGAGAATCCTACTATCGATAGTTTTGAGATAGATTTAAGCA
AAACCGGACCGATGGTTTTAGATGCTTTAATTAAAATCAAAAATGAAATCGATTCTACTTTAGCTTTTAGGCGTTCTTGT
CGGGAAGGAATTTGCGGTAGCTGTTCCATGAACATTGATGGTACAAATACTTTAGCATGTATAAAACCAATAGAAGATAT
ATCAGGCGATATTAAAATCTATCCGCTTCCTCATATGAAAGTAGTAAAAGATTTAGTACCTGATATGTCGCATTTTTACG
CACAATACGAATCTATAGAACCTTGGCTTAAAACCGATAGCCATACCCCTTCAAATTCTGAAAGGTTACAGTCGATTAAA
GACCGAGAAAAGCTTGACGGTTTATATGAGTGCATATTATGTGCTTGCTGTTCTACTTCCTGTCCTAGCTATTGGTGGAA
CAGTGATAAATATTTAGGTCCTGCGATTTTACTACAAGCATATAGATGGATTGCCGATTCAAGGGATGATAATACCTGTG
AACGTCTTGAAGCTTTAGAAGACCCATTTAAGCTTTACCGTTGTCATACGATTATGAATTGTACTAAGACCTGCCCAAAA
AGCTTAAATCCTGCTAAAGCTATAGGTAAAATAAAAAATTTAATTGCAGAACGCCGCGGCGTATGA

Upstream 100 bases:

>100_bases
CTAAAATTAAAAATCAAAGATTTTGTGAATGGTATGCAAGATTGTGAATTAGCTAATTATTTTGTATAGTCCTAAAAATA
AATTTTAAGAGAGTACTTAA

Downstream 100 bases:

>100_bases
TGTTTAATAATTATTTTCTGTTGGATATTTCTTAGTTCGATATCTTGCGCTTTTGCTGTTGATTGTAATAATGCCATGAT
ACAAGGCGACATGAATTATT

Product: succinate dehydrogenase iron-sulfur subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MAELRLPPNSVVKKGKEYKEQEEMFKPRKVKIYRYDPDLDENPTIDSFEIDLSKTGPMVLDALIKIKNEIDSTLAFRRSC
REGICGSCSMNIDGTNTLACIKPIEDISGDIKIYPLPHMKVVKDLVPDMSHFYAQYESIEPWLKTDSHTPSNSERLQSIK
DREKLDGLYECILCACCSTSCPSYWWNSDKYLGPAILLQAYRWIADSRDDNTCERLEALEDPFKLYRCHTIMNCTKTCPK
SLNPAKAIGKIKNLIAERRGV

Sequences:

>Translated_261_residues
MAELRLPPNSVVKKGKEYKEQEEMFKPRKVKIYRYDPDLDENPTIDSFEIDLSKTGPMVLDALIKIKNEIDSTLAFRRSC
REGICGSCSMNIDGTNTLACIKPIEDISGDIKIYPLPHMKVVKDLVPDMSHFYAQYESIEPWLKTDSHTPSNSERLQSIK
DREKLDGLYECILCACCSTSCPSYWWNSDKYLGPAILLQAYRWIADSRDDNTCERLEALEDPFKLYRCHTIMNCTKTCPK
SLNPAKAIGKIKNLIAERRGV
>Mature_260_residues
AELRLPPNSVVKKGKEYKEQEEMFKPRKVKIYRYDPDLDENPTIDSFEIDLSKTGPMVLDALIKIKNEIDSTLAFRRSCR
EGICGSCSMNIDGTNTLACIKPIEDISGDIKIYPLPHMKVVKDLVPDMSHFYAQYESIEPWLKTDSHTPSNSERLQSIKD
REKLDGLYECILCACCSTSCPSYWWNSDKYLGPAILLQAYRWIADSRDDNTCERLEALEDPFKLYRCHTIMNCTKTCPKS
LNPAKAIGKIKNLIAERRGV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=232, Percent_Identity=69.3965517241379, Blast_Score=343, Evalue=1e-94,
Organism=Escherichia coli, GI1786943, Length=234, Percent_Identity=53.8461538461538, Blast_Score=267, Evalue=6e-73,
Organism=Escherichia coli, GI1790596, Length=231, Percent_Identity=32.9004329004329, Blast_Score=144, Evalue=8e-36,
Organism=Caenorhabditis elegans, GI17533915, Length=231, Percent_Identity=65.3679653679654, Blast_Score=323, Evalue=4e-89,
Organism=Saccharomyces cerevisiae, GI6322987, Length=231, Percent_Identity=63.2034632034632, Blast_Score=310, Evalue=1e-85,
Organism=Drosophila melanogaster, GI17137106, Length=234, Percent_Identity=65.3846153846154, Blast_Score=338, Evalue=2e-93,
Organism=Drosophila melanogaster, GI24643156, Length=235, Percent_Identity=63.4042553191489, Blast_Score=315, Evalue=3e-86,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 29873; Mature: 29741

Theoretical pI: Translated: 6.84; Mature: 6.84

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

5.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
7.7 %Cys+Met (Translated Protein)
5.0 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
7.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAELRLPPNSVVKKGKEYKEQEEMFKPRKVKIYRYDPDLDENPTIDSFEIDLSKTGPMVL
CCCCCCCCHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCHHHH
DALIKIKNEIDSTLAFRRSCREGICGSCSMNIDGTNTLACIKPIEDISGDIKIYPLPHMK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHCCCCEEEEECCHHH
VVKDLVPDMSHFYAQYESIEPWLKTDSHTPSNSERLQSIKDREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSDKYLGPAILLQAYRWIADSRDDNTCERLEALEDPFKLYRCHTIMNCTKTCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLNPAKAIGKIKNLIAERRGV
CCCHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AELRLPPNSVVKKGKEYKEQEEMFKPRKVKIYRYDPDLDENPTIDSFEIDLSKTGPMVL
CCCCCCCHHHHHCCHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCCEEEECCCCCHHHH
DALIKIKNEIDSTLAFRRSCREGICGSCSMNIDGTNTLACIKPIEDISGDIKIYPLPHMK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEECCHHHCCCCEEEEECCHHH
VVKDLVPDMSHFYAQYESIEPWLKTDSHTPSNSERLQSIKDREKLDGLYECILCACCSTS
HHHHHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCC
CPSYWWNSDKYLGPAILLQAYRWIADSRDDNTCERLEALEDPFKLYRCHTIMNCTKTCPK
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
SLNPAKAIGKIKNLIAERRGV
CCCHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA