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The map label for this gene is fabZ [H]

Identifier: 157825134

GI number: 157825134

Start: 6824

End: 7261

Strand: Reverse

Name: fabZ [H]

Synonym: A1C_00045

Alternate gene names: 157825134

Gene position: 7261-6824 (Counterclockwise)

Preceding gene: 157825135

Following gene: 157825132

Centisome position: 0.59

GC content: 34.93

Gene sequence:

>438_bases
ATGATCATAGATATTACCGAAATCATGGATTTAATACCTCATCGCTATCCATTTTTACTGGTAGATAGGGTACTTGAAAT
TGACCTTAATAAATCAATATTAGGTATTAAAAACGTTACTGTTAACGAACCGCAATTTACAGGGCATTTTCCGACAAGAC
CTGTTATGCCTGGTGTTCTAATGGTTGAGGCTATGGCACAAATTGCTGCTATATTAGTTGCTAAATCTTTAGGTTCTACT
AAAAATAAAGATGTGTTTTTGATGGCTATTGAAAATGCAAAATTTCGTAGAATCGTTCAGCCCGGGGATACTATGCATAT
CCACGCTGTTATTGATCAGCAAAGAACTAACGTATGGAAATTTTCAAGTACTGTTACGGTTGAAGGTGAAATGGCTGCAG
AAAGTAAGTTTACTGCAATGATTAAAGATAAATCATAG

Upstream 100 bases:

>100_bases
TTACTGCGTAATTCTTCTCGCAATGATGAAAAAACCGTTCCACGCAATAATACCCGCTCGCAATGATAGAAAATTTACAT
TAAAGAAGAGACCTAAATAA

Downstream 100 bases:

>100_bases
GAAAAAGTAGTGGCAAATAACATCCATACTACAGCTATAATTGCAGAAGGTGCAAAGCTCGGTGAAAACGTAAAAATCGG
ACCGTATTGTGTGTTATAGG

Product: (3R)-hydroxymyristoyl-ACP dehydratase

Products: NA

Alternate protein names: (3R)-hydroxymyristoyl ACP dehydrase [H]

Number of amino acids: Translated: 145; Mature: 145

Protein sequence:

>145_residues
MIIDITEIMDLIPHRYPFLLVDRVLEIDLNKSILGIKNVTVNEPQFTGHFPTRPVMPGVLMVEAMAQIAAILVAKSLGST
KNKDVFLMAIENAKFRRIVQPGDTMHIHAVIDQQRTNVWKFSSTVTVEGEMAAESKFTAMIKDKS

Sequences:

>Translated_145_residues
MIIDITEIMDLIPHRYPFLLVDRVLEIDLNKSILGIKNVTVNEPQFTGHFPTRPVMPGVLMVEAMAQIAAILVAKSLGST
KNKDVFLMAIENAKFRRIVQPGDTMHIHAVIDQQRTNVWKFSSTVTVEGEMAAESKFTAMIKDKS
>Mature_145_residues
MIIDITEIMDLIPHRYPFLLVDRVLEIDLNKSILGIKNVTVNEPQFTGHFPTRPVMPGVLMVEAMAQIAAILVAKSLGST
KNKDVFLMAIENAKFRRIVQPGDTMHIHAVIDQQRTNVWKFSSTVTVEGEMAAESKFTAMIKDKS

Specific function: Involved in saturated fatty acids biosynthesis [H]

COG id: COG0764

COG function: function code I; 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thioester dehydratase family. FabZ subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786377, Length=134, Percent_Identity=43.2835820895522, Blast_Score=129, Evalue=6e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013114
- InterPro:   IPR010084 [H]

Pfam domain/function: PF07977 FabA [H]

EC number: 4.2.1.-

Molecular weight: Translated: 16266; Mature: 16266

Theoretical pI: Translated: 7.85; Mature: 7.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
6.2 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
6.2 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDITEIMDLIPHRYPFLLVDRVLEIDLNKSILGIKNVTVNEPQFTGHFPTRPVMPGVL
CEEEHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECEEECCCCCCCCCCCCCCCCHHH
MVEAMAQIAAILVAKSLGSTKNKDVFLMAIENAKFRRIVQPGDTMHIHAVIDQQRTNVWK
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCEEE
FSSTVTVEGEMAAESKFTAMIKDKS
ECCEEEECCCCCCCCEEEEEEECCC
>Mature Secondary Structure
MIIDITEIMDLIPHRYPFLLVDRVLEIDLNKSILGIKNVTVNEPQFTGHFPTRPVMPGVL
CEEEHHHHHHHCCCCCCHHHHHHHHHCCCCCCEEEEECEEECCCCCCCCCCCCCCCCHHH
MVEAMAQIAAILVAKSLGSTKNKDVFLMAIENAKFRRIVQPGDTMHIHAVIDQQRTNVWK
HHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCEEEEECCCCCEEEEEEEECCCCCEEE
FSSTVTVEGEMAAESKFTAMIKDKS
ECCEEEECCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Carbon-Oxygen Lyases; Hydro-Lyases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA