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The map label for this gene is asnC [H]

Identifier: 157373137

GI number: 157373137

Start: 5444749

End: 5445210

Strand: Direct

Name: asnC [H]

Synonym: Spro_4906

Alternate gene names: 157373137

Gene position: 5444749-5445210 (Clockwise)

Preceding gene: 157373135

Following gene: 157373138

Centisome position: 99.92

GC content: 50.0

Gene sequence:

>462_bases
ATGGCTGAAAATTATCAGATCGATAATCTCGATCGCGGCATTCTTAATGCCTTGATGGAAAACGCGCGCACGCCTTATGC
CGAACTGGCGAAGAATTTTGCCGTCAGTCCCGGAACCATTCACGTGCGAGTAGAGAAGATGAAGCAGGCCGGTATCATCA
CCGGAGCAAGGGTAGACGTGAACCCCAAACGCCTGGGCTACGACGTCTGCTGTTTTATCGGCATTATATTAAAGAGTGCC
AAAGACTATCCTTCTGCACTGAAAAAGCTCGAAAGCCTGGAGGAAGTGGTCGAGGCCTATTACACCACCGGCCACTACAG
CGTGTTTATCAAAGTGATGTGCCGCTCGATAGATGCGCTGCAACAAGTACTTATCAACAAGATCCAGACTATCGACGAGA
TCCAGTCAACTGAAACCCTGATCTCGCTGCAGAACCCCATCATGCGTACCATCACTCCCTAG

Upstream 100 bases:

>100_bases
ACCACAATTCAATATCCGCTAATCAATATTGCCTTTTCACTTTTAATCGTTCATTTTGATGCGGTAATAATTCAACAATC
AGCAATTAGTGGGGGATTAA

Downstream 100 bases:

>100_bases
CCAACTATTTACTATACCCATATTATCCACAGGTAGATCCCAGCCGATTCACAGCGTACAATGCTGCCACTTTGAGAAGG
TTGGGATCATTCATTTCATG

Product: DNA-binding transcriptional regulator AsnC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 153; Mature: 152

Protein sequence:

>153_residues
MAENYQIDNLDRGILNALMENARTPYAELAKNFAVSPGTIHVRVEKMKQAGIITGARVDVNPKRLGYDVCCFIGIILKSA
KDYPSALKKLESLEEVVEAYYTTGHYSVFIKVMCRSIDALQQVLINKIQTIDEIQSTETLISLQNPIMRTITP

Sequences:

>Translated_153_residues
MAENYQIDNLDRGILNALMENARTPYAELAKNFAVSPGTIHVRVEKMKQAGIITGARVDVNPKRLGYDVCCFIGIILKSA
KDYPSALKKLESLEEVVEAYYTTGHYSVFIKVMCRSIDALQQVLINKIQTIDEIQSTETLISLQNPIMRTITP
>Mature_152_residues
AENYQIDNLDRGILNALMENARTPYAELAKNFAVSPGTIHVRVEKMKQAGIITGARVDVNPKRLGYDVCCFIGIILKSAK
DYPSALKKLESLEEVVEAYYTTGHYSVFIKVMCRSIDALQQVLINKIQTIDEIQSTETLISLQNPIMRTITP

Specific function: Activator of asnA transcription; autogenous regulator of its own transcription; and repressor of the expression of gidA at a post-transcriptional level [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790182, Length=151, Percent_Identity=88.7417218543046, Blast_Score=277, Evalue=2e-76,
Organism=Escherichia coli, GI1787116, Length=143, Percent_Identity=26.5734265734266, Blast_Score=60, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 17151; Mature: 17020

Theoretical pI: Translated: 7.33; Mature: 7.33

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAENYQIDNLDRGILNALMENARTPYAELAKNFAVSPGTIHVRVEKMKQAGIITGARVDV
CCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEHHHHHHCCCEECCEECC
NPKRLGYDVCCFIGIILKSAKDYPSALKKLESLEEVVEAYYTTGHYSVFIKVMCRSIDAL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QQVLINKIQTIDEIQSTETLISLQNPIMRTITP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC
>Mature Secondary Structure 
AENYQIDNLDRGILNALMENARTPYAELAKNFAVSPGTIHVRVEKMKQAGIITGARVDV
CCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHCCCCCEEEEEHHHHHHCCCEECCEECC
NPKRLGYDVCCFIGIILKSAKDYPSALKKLESLEEVVEAYYTTGHYSVFIKVMCRSIDAL
CHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
QQVLINKIQTIDEIQSTETLISLQNPIMRTITP
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]