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The map label for this gene is gpmI

Identifier: 157373051

GI number: 157373051

Start: 5336022

End: 5337566

Strand: Direct

Name: gpmI

Synonym: Spro_4819

Alternate gene names: 157373051

Gene position: 5336022-5337566 (Clockwise)

Preceding gene: 157373045

Following gene: 229593537

Centisome position: 97.93

GC content: 58.12

Gene sequence:

>1545_bases
ATGTCGAGTAACAAAAAGCCGATGGTACTGGTGATCCTGGACGGTTACGGCCACCGCGAGGAGCAACAGGACAACGCCAT
TCTGAACGCCAAAACGCCGGTAATGGACCGTCTGTGGCAACAGCAGCCACACCAGTTGATCGCCGCGTCCGGGCTGGATG
TCGGCCTGCCTGACGGCCAGATGGGTAACTCGGAAGTCGGCCACGTCAACCTGGGTGCCGGGCGCATCGTTTATCAGGAC
CTGACCCGACTGGATAAAGAGATCAAAGAAGGCGATTTCTTCGCCAACCCGACGCTGACGGCGGCGGTCGATAAGGCCGT
ACAGGCCGGCAAAGCGGTACATATCATGGGCCTGCTGTCACCGGGCGGCGTCCACAGCCACGAAGACCATATTCTGGCGA
TGATTGAACTGGCTTCGCAGCGCGGCGCCAAAGCCGTTTACCTGCACGCCTTCCTGGACGGTCGCGATACCCCGCCACGC
AGCGCAGAAGCCTCTCTGCAACGCTTTAGCGATGCCTTTGCCAAACTGGGCACCGGGCGCATCGCGTCGCTGATTGGCCG
TTATTACGCCATGGACCGCGACAACCGTTGGGACCGTGTTCAACTGGCCTACGATCTGCTGACCCAGGCCAAGGGCGATT
ACGTCACCGATAACGCCGTGGGTGCTCTGCAGGCCGCTTACGAGCGCGGTGAAAACGACGAATTCGTCAAGCCGACCGTG
CTGCAAGCCGCCGGTGAAGCCAAGGCCGAATTACATGATGGCGACGCACTGATCTTCATGAACTTCCGTGCCGATCGCGC
ACGTCAGATCGTCCGCTCTTTCGTTAATGCCGATTTCGACGGTTTCCCTCGCGCCAAAATCATCAATTTTGGTGATTTCG
TGATGTTGACCGAGTATGCCGCCGACATCAAAGCCCCTTGCGCCTATCCGCCTGCATCGCTGAGCAATACCTTCGGTGAG
TGGCTGATGAAACACGACAAGACCCAGCTACGCATCTCGGAAACCGAAAAATACGCTCACGTCACCTTCTTCTTTAACGG
CGGTGTTGAAGAACCCTTCACCGGTGAAGATCGCGTGCTGATCAACTCACCGAAGGTCGCTACCTACGATCTGCAGCCGG
AAATGAGCGCCGCCGAGCTGACCGACAAACTGCTGGCCGCCATTGCCAGTGGTAAATACGACGCCATTATCTGCAACTAT
CCGAATGGGGACATGGTGGGCCATACCGGGGTCTACGACGCGGCAGTGAAGGCAGTAGAAACTCTGGATAACTGCATTGC
TCAGGTGGTTGAGGCAGTTAAGGCCGTCGACGGGCAGTTGCTGATCACCGCCGATCACGGCAACGCCGAACAAATGCGCG
ATCCGGCTACCGGCCAGGCGCATACCGCTCACACCAGCCTGCCGGTACCGCTGATTTACATCGGCAAGCCTGCCAGCGCA
GTCAATGGTGGCAAGCTTTCGGACATCGCGCCAACCATGCTGGCGCTGATGGGAATGGAAATCCCGCAAGAGATGACTGG
TAAGCCGCTGTTCATCGTGGAATAA

Upstream 100 bases:

>100_bases
CGCGTTGTAAAATCGGGCGGTTTTGAGAGTGAATAGTCATCCGCCCGGCCAGGGGTTGATGACTATTCACAACTTAAAAG
TTCATAACGAGGTTAACGCA

Downstream 100 bases:

>100_bases
TCCTTCTCCATGAGGGAAAAGGCGTTTTTTGCACTATCAAGGGTAACCCGAAGCGCAAACGCAGGCAGCCAACCGCTGCC
TGAACGCACCGCGCCAAGGA

Product: phosphoglyceromutase

Products: NA

Alternate protein names: BPG-independent PGAM; Phosphoglyceromutase; iPGM

Number of amino acids: Translated: 514; Mature: 513

Protein sequence:

>514_residues
MSSNKKPMVLVILDGYGHREEQQDNAILNAKTPVMDRLWQQQPHQLIAASGLDVGLPDGQMGNSEVGHVNLGAGRIVYQD
LTRLDKEIKEGDFFANPTLTAAVDKAVQAGKAVHIMGLLSPGGVHSHEDHILAMIELASQRGAKAVYLHAFLDGRDTPPR
SAEASLQRFSDAFAKLGTGRIASLIGRYYAMDRDNRWDRVQLAYDLLTQAKGDYVTDNAVGALQAAYERGENDEFVKPTV
LQAAGEAKAELHDGDALIFMNFRADRARQIVRSFVNADFDGFPRAKIINFGDFVMLTEYAADIKAPCAYPPASLSNTFGE
WLMKHDKTQLRISETEKYAHVTFFFNGGVEEPFTGEDRVLINSPKVATYDLQPEMSAAELTDKLLAAIASGKYDAIICNY
PNGDMVGHTGVYDAAVKAVETLDNCIAQVVEAVKAVDGQLLITADHGNAEQMRDPATGQAHTAHTSLPVPLIYIGKPASA
VNGGKLSDIAPTMLALMGMEIPQEMTGKPLFIVE

Sequences:

>Translated_514_residues
MSSNKKPMVLVILDGYGHREEQQDNAILNAKTPVMDRLWQQQPHQLIAASGLDVGLPDGQMGNSEVGHVNLGAGRIVYQD
LTRLDKEIKEGDFFANPTLTAAVDKAVQAGKAVHIMGLLSPGGVHSHEDHILAMIELASQRGAKAVYLHAFLDGRDTPPR
SAEASLQRFSDAFAKLGTGRIASLIGRYYAMDRDNRWDRVQLAYDLLTQAKGDYVTDNAVGALQAAYERGENDEFVKPTV
LQAAGEAKAELHDGDALIFMNFRADRARQIVRSFVNADFDGFPRAKIINFGDFVMLTEYAADIKAPCAYPPASLSNTFGE
WLMKHDKTQLRISETEKYAHVTFFFNGGVEEPFTGEDRVLINSPKVATYDLQPEMSAAELTDKLLAAIASGKYDAIICNY
PNGDMVGHTGVYDAAVKAVETLDNCIAQVVEAVKAVDGQLLITADHGNAEQMRDPATGQAHTAHTSLPVPLIYIGKPASA
VNGGKLSDIAPTMLALMGMEIPQEMTGKPLFIVE
>Mature_513_residues
SSNKKPMVLVILDGYGHREEQQDNAILNAKTPVMDRLWQQQPHQLIAASGLDVGLPDGQMGNSEVGHVNLGAGRIVYQDL
TRLDKEIKEGDFFANPTLTAAVDKAVQAGKAVHIMGLLSPGGVHSHEDHILAMIELASQRGAKAVYLHAFLDGRDTPPRS
AEASLQRFSDAFAKLGTGRIASLIGRYYAMDRDNRWDRVQLAYDLLTQAKGDYVTDNAVGALQAAYERGENDEFVKPTVL
QAAGEAKAELHDGDALIFMNFRADRARQIVRSFVNADFDGFPRAKIINFGDFVMLTEYAADIKAPCAYPPASLSNTFGEW
LMKHDKTQLRISETEKYAHVTFFFNGGVEEPFTGEDRVLINSPKVATYDLQPEMSAAELTDKLLAAIASGKYDAIICNYP
NGDMVGHTGVYDAAVKAVETLDNCIAQVVEAVKAVDGQLLITADHGNAEQMRDPATGQAHTAHTSLPVPLIYIGKPASAV
NGGKLSDIAPTMLALMGMEIPQEMTGKPLFIVE

Specific function: Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate

COG id: COG0696

COG function: function code G; Phosphoglyceromutase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BPG-independent phosphoglycerate mutase family

Homologues:

Organism=Escherichia coli, GI1790041, Length=515, Percent_Identity=79.2233009708738, Blast_Score=854, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17507741, Length=525, Percent_Identity=45.1428571428571, Blast_Score=436, Evalue=1e-122,
Organism=Caenorhabditis elegans, GI32564249, Length=525, Percent_Identity=45.1428571428571, Blast_Score=436, Evalue=1e-122,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): GPMI_SERP5 (A8GLC2)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001481040.1
- ProteinModelPortal:   A8GLC2
- SMR:   A8GLC2
- STRING:   A8GLC2
- GeneID:   5605803
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_4819
- eggNOG:   COG0696
- HOGENOM:   HBG613255
- OMA:   DHGNAEL
- ProtClustDB:   PRK05434
- BioCyc:   SPRO399741:SPRO_4819-MONOMER
- GO:   GO:0005737
- GO:   GO:0006096
- HAMAP:   MF_01038
- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR011258
- InterPro:   IPR006124
- InterPro:   IPR005995
- Gene3D:   G3DSA:3.40.720.10
- Gene3D:   G3DSA:3.40.1450.10
- PIRSF:   PIRSF001492
- TIGRFAMs:   TIGR01307

Pfam domain/function: PF06415 iPGM_N; PF01676 Metalloenzyme; SSF53649 Alkaline_phosphatase_core; SSF64158 BPG-indep_PGM_N

EC number: =5.4.2.1

Molecular weight: Translated: 55875; Mature: 55744

Theoretical pI: Translated: 5.04; Mature: 5.04

Prosite motif: NA

Important sites: ACT_SITE 64-64

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSNKKPMVLVILDGYGHREEQQDNAILNAKTPVMDRLWQQQPHQLIAASGLDVGLPDGQ
CCCCCCCEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHCCHHEEHCCCCCCCCCCCC
MGNSEVGHVNLGAGRIVYQDLTRLDKEIKEGDFFANPTLTAAVDKAVQAGKAVHIMGLLS
CCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEC
PGGVHSHEDHILAMIELASQRGAKAVYLHAFLDGRDTPPRSAEASLQRFSDAFAKLGTGR
CCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCH
IASLIGRYYAMDRDNRWDRVQLAYDLLTQAKGDYVTDNAVGALQAAYERGENDEFVKPTV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCCCCHHH
LQAAGEAKAELHDGDALIFMNFRADRARQIVRSFVNADFDGFPRAKIINFGDFVMLTEYA
HHHCCCCCCEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEHHHHH
ADIKAPCAYPPASLSNTFGEWLMKHDKTQLRISETEKYAHVTFFFNGGVEEPFTGEDRVL
HHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCEEE
INSPKVATYDLQPEMSAAELTDKLLAAIASGKYDAIICNYPNGDMVGHTGVYDAAVKAVE
EECCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
TLDNCIAQVVEAVKAVDGQLLITADHGNAEQMRDPATGQAHTAHTSLPVPLIYIGKPASA
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCC
VNGGKLSDIAPTMLALMGMEIPQEMTGKPLFIVE
CCCCCCHHHHHHHHHHHCCCCCHHHCCCCEEEEC
>Mature Secondary Structure 
SSNKKPMVLVILDGYGHREEQQDNAILNAKTPVMDRLWQQQPHQLIAASGLDVGLPDGQ
CCCCCCEEEEEECCCCCCCCCCCCCEEECCCHHHHHHHHHCCHHEEHCCCCCCCCCCCC
MGNSEVGHVNLGAGRIVYQDLTRLDKEIKEGDFFANPTLTAAVDKAVQAGKAVHIMGLLS
CCCCCCCEEECCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEC
PGGVHSHEDHILAMIELASQRGAKAVYLHAFLDGRDTPPRSAEASLQRFSDAFAKLGTGR
CCCCCCCCCHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCH
IASLIGRYYAMDRDNRWDRVQLAYDLLTQAKGDYVTDNAVGALQAAYERGENDEFVKPTV
HHHHHHHHHHCCCCCCCCHHHHHHHHHHHCCCCEECCCHHHHHHHHHHCCCCCCCCCHHH
LQAAGEAKAELHDGDALIFMNFRADRARQIVRSFVNADFDGFPRAKIINFGDFVMLTEYA
HHHCCCCCCEECCCCEEEEEECCCHHHHHHHHHHHCCCCCCCCCEEEECCCCEEEHHHHH
ADIKAPCAYPPASLSNTFGEWLMKHDKTQLRISETEKYAHVTFFFNGGVEEPFTGEDRVL
HHCCCCCCCCCHHHHHHHHHHHHHCCCCEEEEECCCCEEEEEEEEECCCCCCCCCCCEEE
INSPKVATYDLQPEMSAAELTDKLLAAIASGKYDAIICNYPNGDMVGHTGVYDAAVKAVE
EECCCEEEEECCCCCCHHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCHHHHHHHHHH
TLDNCIAQVVEAVKAVDGQLLITADHGNAEQMRDPATGQAHTAHTSLPVPLIYIGKPASA
HHHHHHHHHHHHHHHCCCCEEEEECCCCHHHHCCCCCCCCCCCCCCCCEEEEEECCCCCC
VNGGKLSDIAPTMLALMGMEIPQEMTGKPLFIVE
CCCCCCHHHHHHHHHHHCCCCCHHHCCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA