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The map label for this gene is fkpA [H]

Identifier: 157372385

GI number: 157372385

Start: 4604600

End: 4606216

Strand: Direct

Name: fkpA [H]

Synonym: Spro_4152

Alternate gene names: 157372385

Gene position: 4604600-4606216 (Clockwise)

Preceding gene: 157372384

Following gene: 157372386

Centisome position: 84.51

GC content: 53.0

Gene sequence:

>1617_bases
ATGAATCGTAAATACGCGCAGTCGCCTTCCGGCTTGCAGTCTCGGTTAAGCGGGTTAATGGTCGCTATCGGCCTGGCGGC
ATCCTCCACCGTACAGGCTGCGCCGCAGGCTGGCGTACCTGCTCTTTTGCAGTTTGCCGAACAATATCAACAACAATCAA
AAGACGCAGCACCGCCGGTAACCAAACCGGCGGTGAAGCCGGCCGATACTGGAGCAAAGCCTCCCGCTAATAAAACTGGC
AACCCACAAGGCAACCGCTCTTCCCGGGAAAAAGCAGCTGCCGCTGCACTTTGGCAAACCAAAGATGCCAAGATACGGCA
CCTGCAGGAAACCATTGTCCAGCTTGAGCAGCAGATGAGCATATTGGAAAAAAAACAGGCGAAAACGGCACCTGACGCCC
CTCAAATATCAATAGATACCACAGCACTGAGCAGTCTGGTTCATGGGGTGCGCAAAGCTCTGTCGCCCACGCCGGAGGAA
ACTCAGGTAAAAGAACGTCTGCGGCAGGCACAGCAACAGATTAGTTTGGCGAAGACGGCGGAGAAAGACCTGCGCACAGA
AAACGACAGGCTTAAAAATCAACTGACCGTGATGAAAACGCAAAACCAGGCATCGGCAACCGAAGCGCATAACACCCTCA
CAGCCCAGTTACAGCACGTTGAACAGGATAAAATCACGTTACAAACGCACCTGTCAGAAGCCCAAAACAGAAACCAAACG
CTGACCACCGCCAGTGAAAACGTAAAGGCGCAGTTGGCGAGGTTAAAAACGGCAGAGTCCGAGCTGCGTGCAACCCATAC
GCAGACACAGACACAGCTGAATGAACTGCTGCTACAGCGCAACACAATGCAAAAAGATCTGGATGAACAGGTGACTGTGG
CCGCTAACCTAAAAGCCGAACTGAGTGACTTGCGGAAGGTCGCCCCAGAAAAAATCCAAGCGGACAGGATGAAACAGCCT
GCTGTACGCCAGGCTTACGCCGCTGGCGTTTCGTTGGGTGAGGAAGTCTTGCAAATGCATGCGGAGCGCCAGAAATGGGG
AGTAAAAATCGACAAGCAAGTATTGCTGACCGGGCTGTTCGATACCTTCTCCGGGCAGCGACAGTTGGATGATGAGGCAC
TCAATCAGGCACTGGCCGAATCTGAGCAGCAGGTGACGAAAGCCAGAAATAACGTAGTGGCAACACAGCTAAAACAGGAT
AATGCTTACCTGGCCAGCTTCAAAAAAGACAAACGGGTTAAAACTACCGCCACCGGAGCTTGGTATCGCGTTGACTATAC
CGGCGATGCGCCGATCCCTACCGGTGCCATCCTGGACGTCGTTATAAAAGAAACGCTTACCGATGGCACCGTGATCCAGG
ATATGGACACCAACGGTGCGGTGCTGTCTCAGCCTCTGGCGCAATTCCCGCCGTTATTTGCCGACGCATTGAAGCAATTA
AAAAACCACGGTTCATTAACCCTGGTGGTGCCTCCTGAGCTGGCCTACGGAGAAAAAGGTTATCCGCCAAGCGTACCGCC
CAACGCCACCATGGTGTACCAACTACGTATTGCCGAAATATACCCCGAAACACAGAAAAAAAAGGAGGCGCAGGACTCTG
CAAAATCCCCCCGGTAG

Upstream 100 bases:

>100_bases
ACACCGTAGATTCACTCTACCGTTATCGCGTCAATTTACTCTGTGCTCAAATCAACCAGGCCGTGCTCAATCGCCTGGCT
GAACAGGGTGGAACAGCGCA

Downstream 100 bases:

>100_bases
CCTCATGTTCTCTGGCAAATCGCCATTGGCTGCTGACGACTCCCCCCTTCGTCAGCAGCCATTTTTTCGTTATGCCTATT
CCAATCTCTGAACTGAATAA

Product: FKBP-type peptidyl-prolyl isomerase domain-containing protein

Products: NA

Alternate protein names: PPIase; Rotamase [H]

Number of amino acids: Translated: 538; Mature: 538

Protein sequence:

>538_residues
MNRKYAQSPSGLQSRLSGLMVAIGLAASSTVQAAPQAGVPALLQFAEQYQQQSKDAAPPVTKPAVKPADTGAKPPANKTG
NPQGNRSSREKAAAAALWQTKDAKIRHLQETIVQLEQQMSILEKKQAKTAPDAPQISIDTTALSSLVHGVRKALSPTPEE
TQVKERLRQAQQQISLAKTAEKDLRTENDRLKNQLTVMKTQNQASATEAHNTLTAQLQHVEQDKITLQTHLSEAQNRNQT
LTTASENVKAQLARLKTAESELRATHTQTQTQLNELLLQRNTMQKDLDEQVTVAANLKAELSDLRKVAPEKIQADRMKQP
AVRQAYAAGVSLGEEVLQMHAERQKWGVKIDKQVLLTGLFDTFSGQRQLDDEALNQALAESEQQVTKARNNVVATQLKQD
NAYLASFKKDKRVKTTATGAWYRVDYTGDAPIPTGAILDVVIKETLTDGTVIQDMDTNGAVLSQPLAQFPPLFADALKQL
KNHGSLTLVVPPELAYGEKGYPPSVPPNATMVYQLRIAEIYPETQKKKEAQDSAKSPR

Sequences:

>Translated_538_residues
MNRKYAQSPSGLQSRLSGLMVAIGLAASSTVQAAPQAGVPALLQFAEQYQQQSKDAAPPVTKPAVKPADTGAKPPANKTG
NPQGNRSSREKAAAAALWQTKDAKIRHLQETIVQLEQQMSILEKKQAKTAPDAPQISIDTTALSSLVHGVRKALSPTPEE
TQVKERLRQAQQQISLAKTAEKDLRTENDRLKNQLTVMKTQNQASATEAHNTLTAQLQHVEQDKITLQTHLSEAQNRNQT
LTTASENVKAQLARLKTAESELRATHTQTQTQLNELLLQRNTMQKDLDEQVTVAANLKAELSDLRKVAPEKIQADRMKQP
AVRQAYAAGVSLGEEVLQMHAERQKWGVKIDKQVLLTGLFDTFSGQRQLDDEALNQALAESEQQVTKARNNVVATQLKQD
NAYLASFKKDKRVKTTATGAWYRVDYTGDAPIPTGAILDVVIKETLTDGTVIQDMDTNGAVLSQPLAQFPPLFADALKQL
KNHGSLTLVVPPELAYGEKGYPPSVPPNATMVYQLRIAEIYPETQKKKEAQDSAKSPR
>Mature_538_residues
MNRKYAQSPSGLQSRLSGLMVAIGLAASSTVQAAPQAGVPALLQFAEQYQQQSKDAAPPVTKPAVKPADTGAKPPANKTG
NPQGNRSSREKAAAAALWQTKDAKIRHLQETIVQLEQQMSILEKKQAKTAPDAPQISIDTTALSSLVHGVRKALSPTPEE
TQVKERLRQAQQQISLAKTAEKDLRTENDRLKNQLTVMKTQNQASATEAHNTLTAQLQHVEQDKITLQTHLSEAQNRNQT
LTTASENVKAQLARLKTAESELRATHTQTQTQLNELLLQRNTMQKDLDEQVTVAANLKAELSDLRKVAPEKIQADRMKQP
AVRQAYAAGVSLGEEVLQMHAERQKWGVKIDKQVLLTGLFDTFSGQRQLDDEALNQALAESEQQVTKARNNVVATQLKQD
NAYLASFKKDKRVKTTATGAWYRVDYTGDAPIPTGAILDVVIKETLTDGTVIQDMDTNGAVLSQPLAQFPPLFADALKQL
KNHGSLTLVVPPELAYGEKGYPPSVPPNATMVYQLRIAEIYPETQKKKEAQDSAKSPR

Specific function: PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides [H]

COG id: COG0545

COG function: function code O; FKBP-type peptidyl-prolyl cis-trans isomerases 1

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PPIase FKBP-type domain [H]

Homologues:

Organism=Escherichia coli, GI1789745, Length=205, Percent_Identity=34.6341463414634, Blast_Score=100, Evalue=2e-22,

Paralogues:

None

Copy number: 200 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001179
- InterPro:   IPR000774 [H]

Pfam domain/function: PF00254 FKBP_C; PF01346 FKBP_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 58982; Mature: 58982

Theoretical pI: Translated: 9.85; Mature: 9.85

Prosite motif: PS50059 FKBP_PPIASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNRKYAQSPSGLQSRLSGLMVAIGLAASSTVQAAPQAGVPALLQFAEQYQQQSKDAAPPV
CCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
TKPAVKPADTGAKPPANKTGNPQGNRSSREKAAAAALWQTKDAKIRHLQETIVQLEQQMS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ILEKKQAKTAPDAPQISIDTTALSSLVHGVRKALSPTPEETQVKERLRQAQQQISLAKTA
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
EKDLRTENDRLKNQLTVMKTQNQASATEAHNTLTAQLQHVEQDKITLQTHLSEAQNRNQT
HHHHHCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTTASENVKAQLARLKTAESELRATHTQTQTQLNELLLQRNTMQKDLDEQVTVAANLKAE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHH
LSDLRKVAPEKIQADRMKQPAVRQAYAAGVSLGEEVLQMHAERQKWGVKIDKQVLLTGLF
HHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DTFSGQRQLDDEALNQALAESEQQVTKARNNVVATQLKQDNAYLASFKKDKRVKTTATGA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCEEEEECCC
WYRVDYTGDAPIPTGAILDVVIKETLTDGTVIQDMDTNGAVLSQPLAQFPPLFADALKQL
EEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHCHHHHCCCHHHHHHHHH
KNHGSLTLVVPPELAYGEKGYPPSVPPNATMVYQLRIAEIYPETQKKKEAQDSAKSPR
HCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCHHHHHHHHHHCCCCC
>Mature Secondary Structure
MNRKYAQSPSGLQSRLSGLMVAIGLAASSTVQAAPQAGVPALLQFAEQYQQQSKDAAPPV
CCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCCCCCHHHHHHHHHHHHHHCCCCCCCC
TKPAVKPADTGAKPPANKTGNPQGNRSSREKAAAAALWQTKDAKIRHLQETIVQLEQQMS
CCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHH
ILEKKQAKTAPDAPQISIDTTALSSLVHGVRKALSPTPEETQVKERLRQAQQQISLAKTA
HHHHHHHCCCCCCCCEEEHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
EKDLRTENDRLKNQLTVMKTQNQASATEAHNTLTAQLQHVEQDKITLQTHLSEAQNRNQT
HHHHHCHHHHHHHHHHHEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTTASENVKAQLARLKTAESELRATHTQTQTQLNELLLQRNTMQKDLDEQVTVAANLKAE
EEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEHHHHHHHH
LSDLRKVAPEKIQADRMKQPAVRQAYAAGVSLGEEVLQMHAERQKWGVKIDKQVLLTGLF
HHHHHHHCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
DTFSGQRQLDDEALNQALAESEQQVTKARNNVVATQLKQDNAYLASFKKDKRVKTTATGA
HHCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCEEEEECCC
WYRVDYTGDAPIPTGAILDVVIKETLTDGTVIQDMDTNGAVLSQPLAQFPPLFADALKQL
EEEEEECCCCCCCCHHHHHHHHHHHCCCCCEEEECCCCCHHHHCHHHHCCCHHHHHHHHH
KNHGSLTLVVPPELAYGEKGYPPSVPPNATMVYQLRIAEIYPETQKKKEAQDSAKSPR
HCCCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEEEEHHHCCCHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]