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The map label for this gene is csd [H]

Identifier: 157372104

GI number: 157372104

Start: 4282581

End: 4283810

Strand: Direct

Name: csd [H]

Synonym: Spro_3869

Alternate gene names: 157372104

Gene position: 4282581-4283810 (Clockwise)

Preceding gene: 157372103

Following gene: 157372105

Centisome position: 78.6

GC content: 54.31

Gene sequence:

>1230_bases
ATGACATTTACTCCCGAACTCGCCCGGGCTCAGTTTAGTGCGCTGACCCAACGCCATGATGACAAACCCGTTATCTTTTT
CGATGGGCCTGGCGGTTCTCAGGTTTCGCAAGGGGTGCTGGAGAAAATGACCCACTACCTGGGGAAATATAACGCCAATC
TGGGCGGACATTATTTTTCCAGCCATAAAACAACCGAGGTGATGGATCATGCAAGGGAATCGGTGCGCGCCTTCTTGAAT
GCACCCTCGCCCGATAATATCGTTTTTGGCATGAACATGACCTCGCTGACGTTCCACCTCAGCCGCATCATTAGCCGTAG
TTGGCAAGCCGGGGACGAAATCATCGTTACCGAGCTGGATCACTACGCCAATGTCTCCAGCTGGCAGCAGGCGGCAAATG
ACAAGCAAGTCACCGTGCATCAAATCCCTCTGCAACAAGCGGATTGTTCTTTGGATACCGCCCGGCTGTGCGAAAAGATT
ACCGCCAAAACTCGCCTGGTCGCAGTCAGCTATGCGTCTAATGTTACGGGCAGCATCGTCGATATTAAAGCCATCACCGA
AGCCGCCCACCGGGTCGGCGCGCAGGTTTATGTCGACGCAGTGCATTATGCTCCGCATAACCTGATCGATGTGCAGGCGC
TGGGTTGCGACTTTCTGGTGTGTTCCGCCTATAAATTCTTTGGCCCGCATATCGGCATGGCCTATATCGCGCCGCAATGG
CTGCAACGGCTGCAGCCCTATAAAGTCGAGCCGGCCACCGACATCGGCCCAGGCCGTTTTGAGACCGGCACCCAAAGTTT
CGAAGGGCTGGCCGGTGTAACGGCGGCGATTGATTACCTGGCGCAATGGGGTACAGCAGGCGCTCCTTTAAGGCAGCGTT
TACAGGAAAGTTTTGCCGACTATCACCGCCATGAAGAGAGCCTGTGCAGGTACTTTTTGCAACGCTTATCGCAAATCGAT
GATGTACAACTCTACGGTTCACCCGTGGCGGATCCCCAACGCCGGACGCCCACGTTTGCATTGACCTTTAAGCGGCATTC
GCCTGAACAGGTTGCCCGCAGGTTAGGCCAACACAATATCTGCGTCGGCAGCGGACACTTCTATGCACTGGGGTTAATTC
GACGGTTGAACCTGCAGGACAGCGGCGGCGTGCTGCGCATTGGGATGATGCATTACAATACTCTGCAAGAAATCGATACT
TTGTTTGAGATACTTGCCAGCGGAAGGTAG

Upstream 100 bases:

>100_bases
ACAGTAAGCTATGGCATAACGCCACGCCGATCAGCGCCATTGTCCCGGAACAAGAAGGGCATCTTGACCTGTTTGTCCTG
ACCGCGCGAGGGGAAAAAGC

Downstream 100 bases:

>100_bases
TGACAGGAAGTTTTGGAGCGGGTGAAGGGAGTAGAATACCAGCACCTAAAGGCAGTAGACATGGCAATCACTGACTTTAC
AAAAACTAAACTACACACAT

Product: cysteine desulfurase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 409; Mature: 408

Protein sequence:

>409_residues
MTFTPELARAQFSALTQRHDDKPVIFFDGPGGSQVSQGVLEKMTHYLGKYNANLGGHYFSSHKTTEVMDHARESVRAFLN
APSPDNIVFGMNMTSLTFHLSRIISRSWQAGDEIIVTELDHYANVSSWQQAANDKQVTVHQIPLQQADCSLDTARLCEKI
TAKTRLVAVSYASNVTGSIVDIKAITEAAHRVGAQVYVDAVHYAPHNLIDVQALGCDFLVCSAYKFFGPHIGMAYIAPQW
LQRLQPYKVEPATDIGPGRFETGTQSFEGLAGVTAAIDYLAQWGTAGAPLRQRLQESFADYHRHEESLCRYFLQRLSQID
DVQLYGSPVADPQRRTPTFALTFKRHSPEQVARRLGQHNICVGSGHFYALGLIRRLNLQDSGGVLRIGMMHYNTLQEIDT
LFEILASGR

Sequences:

>Translated_409_residues
MTFTPELARAQFSALTQRHDDKPVIFFDGPGGSQVSQGVLEKMTHYLGKYNANLGGHYFSSHKTTEVMDHARESVRAFLN
APSPDNIVFGMNMTSLTFHLSRIISRSWQAGDEIIVTELDHYANVSSWQQAANDKQVTVHQIPLQQADCSLDTARLCEKI
TAKTRLVAVSYASNVTGSIVDIKAITEAAHRVGAQVYVDAVHYAPHNLIDVQALGCDFLVCSAYKFFGPHIGMAYIAPQW
LQRLQPYKVEPATDIGPGRFETGTQSFEGLAGVTAAIDYLAQWGTAGAPLRQRLQESFADYHRHEESLCRYFLQRLSQID
DVQLYGSPVADPQRRTPTFALTFKRHSPEQVARRLGQHNICVGSGHFYALGLIRRLNLQDSGGVLRIGMMHYNTLQEIDT
LFEILASGR
>Mature_408_residues
TFTPELARAQFSALTQRHDDKPVIFFDGPGGSQVSQGVLEKMTHYLGKYNANLGGHYFSSHKTTEVMDHARESVRAFLNA
PSPDNIVFGMNMTSLTFHLSRIISRSWQAGDEIIVTELDHYANVSSWQQAANDKQVTVHQIPLQQADCSLDTARLCEKIT
AKTRLVAVSYASNVTGSIVDIKAITEAAHRVGAQVYVDAVHYAPHNLIDVQALGCDFLVCSAYKFFGPHIGMAYIAPQWL
QRLQPYKVEPATDIGPGRFETGTQSFEGLAGVTAAIDYLAQWGTAGAPLRQRLQESFADYHRHEESLCRYFLQRLSQIDD
VQLYGSPVADPQRRTPTFALTFKRHSPEQVARRLGQHNICVGSGHFYALGLIRRLNLQDSGGVLRIGMMHYNTLQEIDTL
FEILASGR

Specific function: Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L- selenocystine to produce L-alanine [H]

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Homo sapiens, GI156713448, Length=309, Percent_Identity=22.0064724919094, Blast_Score=66, Evalue=5e-11,
Organism=Escherichia coli, GI1787970, Length=421, Percent_Identity=29.9287410926366, Blast_Score=172, Evalue=2e-44,
Organism=Escherichia coli, GI1789175, Length=414, Percent_Identity=27.536231884058, Blast_Score=120, Evalue=2e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7 [H]

Molecular weight: Translated: 45559; Mature: 45428

Theoretical pI: Translated: 7.15; Mature: 7.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFTPELARAQFSALTQRHDDKPVIFFDGPGGSQVSQGVLEKMTHYLGKYNANLGGHYFS
CCCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
SHKTTEVMDHARESVRAFLNAPSPDNIVFGMNMTSLTFHLSRIISRSWQAGDEIIVTELD
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECH
HYANVSSWQQAANDKQVTVHQIPLQQADCSLDTARLCEKITAKTRLVAVSYASNVTGSIV
HHCCHHHHHHHCCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCEE
DIKAITEAAHRVGAQVYVDAVHYAPHNLIDVQALGCDFLVCSAYKFFGPHIGMAYIAPQW
HHHHHHHHHHHCCCCEEEEEHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHH
LQRLQPYKVEPATDIGPGRFETGTQSFEGLAGVTAAIDYLAQWGTAGAPLRQRLQESFAD
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YHRHEESLCRYFLQRLSQIDDVQLYGSPVADPQRRTPTFALTFKRHSPEQVARRLGQHNI
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCE
CVGSGHFYALGLIRRLNLQDSGGVLRIGMMHYNTLQEIDTLFEILASGR
EEECCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFTPELARAQFSALTQRHDDKPVIFFDGPGGSQVSQGVLEKMTHYLGKYNANLGGHYFS
CCCHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCC
SHKTTEVMDHARESVRAFLNAPSPDNIVFGMNMTSLTFHLSRIISRSWQAGDEIIVTELD
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCHHHHHHHHHHHHHHHCCCCCCEEEEECH
HYANVSSWQQAANDKQVTVHQIPLQQADCSLDTARLCEKITAKTRLVAVSYASNVTGSIV
HHCCHHHHHHHCCCCCEEEEECCCHHCCCCCCHHHHHHHHHHHHEEEEEEECCCCCCCEE
DIKAITEAAHRVGAQVYVDAVHYAPHNLIDVQALGCDFLVCSAYKFFGPHIGMAYIAPQW
HHHHHHHHHHHCCCCEEEEEHHCCCCCEEEEECCCCHHHHHHHHHHHCCCCCHHHHHHHH
LQRLQPYKVEPATDIGPGRFETGTQSFEGLAGVTAAIDYLAQWGTAGAPLRQRLQESFAD
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHH
YHRHEESLCRYFLQRLSQIDDVQLYGSPVADPQRRTPTFALTFKRHSPEQVARRLGQHNI
HHHHHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCEEEEEEECCCHHHHHHHCCCCCE
CVGSGHFYALGLIRRLNLQDSGGVLRIGMMHYNTLQEIDTLFEILASGR
EEECCCHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]