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The map label for this gene is yiaY [H]

Identifier: 157371893

GI number: 157371893

Start: 4051159

End: 4052310

Strand: Direct

Name: yiaY [H]

Synonym: Spro_3658

Alternate gene names: 157371893

Gene position: 4051159-4052310 (Clockwise)

Preceding gene: 157371892

Following gene: 157371897

Centisome position: 74.35

GC content: 56.6

Gene sequence:

>1152_bases
ATGGCTGCCTCAACTTTCTTTATCCCTCCCGTCAATATGATTGGTTCCGGCTGTCTGGACGAAGCGGCAAAGACCATGAA
ACAACAGGGATTGCGCCACGCATTGATCGTGACCGACAAAGTGTTGAATAACATCGGCGTGGTCGCCCAGGTTCAACAGT
TACTCGCCGTACAACAGATCGAAAGCTGCGTTTATGACGGTACTCACCCTAACCCAACTACCCTTAACGTGAAACAGGGC
CTGGCGCTGCTGCAAGAACACCGCTGTGACTGCGTAGTTTCTCTTGGCGGCGGCTCGCCACACGACTGTGCCAAAGGCAT
CGCGCTGGTCGCGACCAACGGTGGAGAGATCAAGGATTATGAAGGTGTCGATCGTTCCGCCAAACCGCAGTTGCCGATGA
TTGCCATCAACACTACCGCCGGCACTGCCTCTGAAATGACCCGTTTTTGCATCATCACCGATGAAGCACGCCACATCAAA
ATGGCGATTGTCGACAAGCACGTCACCCCAATCCTGTCGGTCAACGACCCGCACCTGATGGCCGGTATGCCGAAAGGCCT
GACCGCCGCCACCGGGATGGATGCATTAACCCACGCGATTGAGGCCTATGTTTCCAGCGCCGCCAACCCGATTACCGATG
CCTGTGCACTAAAAGCCGTCACCATGATTGCCGAATCGCTGCGCGACGCGGTCGCCGACGGCAGCAATATGCAGGCGCGT
GAAAATATGGCTTACGCCCAGTTCCTGGCCGGAATGGCCTTCAACAACGCTTCTCTCGGTTATGTGCACGCGATGGCGCA
CCAGCTTGGCGGTTTCTACGATCTGCCGCATGGGGTATGTAACGCGGTGCTGCTGCCGCACGTGCAGGAGTTCAACGCCC
GGGTTTGCGCGCCACGGTTGAAAGACATCGCCGTCGCCATGGGGTTGGATGTGAAACATCTTAACGACCCACAGGGCGCC
GCTGCCTGTATCGCCGCCATTCGTTTGCTGGCAAAAGACGTCGGCATCCCGGCTGGGCTGCTCGATTTAAAAGTGAAAGA
ACAGGACTTCGATACGCTGGCGGCCAATGCTTTGAAAGATGCATGCGGTTTCACCAACCCGATACAAGCTACCCACGAGC
AGATCGTCGCCATCTTCCGCGCGGCAATGTAA

Upstream 100 bases:

>100_bases
ACAACGGGTATACCGCGAAATTGCGATAGATCATAAACGCTTAATAATTAGCGTAGTAATGTTTGAGGCAAGCAATAAAG
CTTTTATCAAGGAGTGACTT

Downstream 100 bases:

>100_bases
TCCATTAAAAACAGTAAAGGGCGGATATCCGCCCTTATACTTCGTTAAAGCCAGTTATTAGGGAGAGCGTGCCGAAGGGG
TCATAGCAGCTTTAGCTGCC

Product: iron-containing alcohol dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 383; Mature: 382

Protein sequence:

>383_residues
MAASTFFIPPVNMIGSGCLDEAAKTMKQQGLRHALIVTDKVLNNIGVVAQVQQLLAVQQIESCVYDGTHPNPTTLNVKQG
LALLQEHRCDCVVSLGGGSPHDCAKGIALVATNGGEIKDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
MAIVDKHVTPILSVNDPHLMAGMPKGLTAATGMDALTHAIEAYVSSAANPITDACALKAVTMIAESLRDAVADGSNMQAR
ENMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQEFNARVCAPRLKDIAVAMGLDVKHLNDPQGA
AACIAAIRLLAKDVGIPAGLLDLKVKEQDFDTLAANALKDACGFTNPIQATHEQIVAIFRAAM

Sequences:

>Translated_383_residues
MAASTFFIPPVNMIGSGCLDEAAKTMKQQGLRHALIVTDKVLNNIGVVAQVQQLLAVQQIESCVYDGTHPNPTTLNVKQG
LALLQEHRCDCVVSLGGGSPHDCAKGIALVATNGGEIKDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
MAIVDKHVTPILSVNDPHLMAGMPKGLTAATGMDALTHAIEAYVSSAANPITDACALKAVTMIAESLRDAVADGSNMQAR
ENMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQEFNARVCAPRLKDIAVAMGLDVKHLNDPQGA
AACIAAIRLLAKDVGIPAGLLDLKVKEQDFDTLAANALKDACGFTNPIQATHEQIVAIFRAAM
>Mature_382_residues
AASTFFIPPVNMIGSGCLDEAAKTMKQQGLRHALIVTDKVLNNIGVVAQVQQLLAVQQIESCVYDGTHPNPTTLNVKQGL
ALLQEHRCDCVVSLGGGSPHDCAKGIALVATNGGEIKDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIKM
AIVDKHVTPILSVNDPHLMAGMPKGLTAATGMDALTHAIEAYVSSAANPITDACALKAVTMIAESLRDAVADGSNMQARE
NMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQEFNARVCAPRLKDIAVAMGLDVKHLNDPQGAA
ACIAAIRLLAKDVGIPAGLLDLKVKEQDFDTLAANALKDACGFTNPIQATHEQIVAIFRAAM

Specific function: Unknown

COG id: COG1454

COG function: function code C; Alcohol dehydrogenase, class IV

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-containing alcohol dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI133922590, Length=409, Percent_Identity=25.9168704156479, Blast_Score=119, Evalue=3e-27,
Organism=Escherichia coli, GI48994951, Length=383, Percent_Identity=76.2402088772846, Blast_Score=590, Evalue=1e-170,
Organism=Escherichia coli, GI1789163, Length=385, Percent_Identity=42.0779220779221, Blast_Score=304, Evalue=6e-84,
Organism=Escherichia coli, GI87082107, Length=378, Percent_Identity=38.6243386243386, Blast_Score=243, Evalue=2e-65,
Organism=Escherichia coli, GI1787493, Length=392, Percent_Identity=33.9285714285714, Blast_Score=190, Evalue=1e-49,
Organism=Escherichia coli, GI1789386, Length=309, Percent_Identity=25.8899676375405, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17537053, Length=411, Percent_Identity=25.3041362530414, Blast_Score=129, Evalue=2e-30,
Organism=Saccharomyces cerevisiae, GI6321181, Length=379, Percent_Identity=56.2005277044855, Blast_Score=426, Evalue=1e-120,
Organism=Drosophila melanogaster, GI24657991, Length=423, Percent_Identity=26.241134751773, Blast_Score=117, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001670
- InterPro:   IPR018211 [H]

Pfam domain/function: PF00465 Fe-ADH [H]

EC number: =1.1.1.1 [H]

Molecular weight: Translated: 40454; Mature: 40323

Theoretical pI: Translated: 6.38; Mature: 6.38

Prosite motif: PS00913 ADH_IRON_1 ; PS00060 ADH_IRON_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.9 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
7.0 %Cys+Met (Translated Protein)
2.9 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
6.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAASTFFIPPVNMIGSGCLDEAAKTMKQQGLRHALIVTDKVLNNIGVVAQVQQLLAVQQI
CCCCEEECCCHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ESCVYDGTHPNPTTLNVKQGLALLQEHRCDCVVSLGGGSPHDCAKGIALVATNGGEIKDY
HHHHCCCCCCCCCEEEHHHHHHHHHHCCCCEEEECCCCCHHHHHCCEEEEEECCCCCCCC
EGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIKMAIVDKHVTPILSVNDPHLM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEECCCCCCEEECCCCHHC
AGMPKGLTAATGMDALTHAIEAYVSSAANPITDACALKAVTMIAESLRDAVADGSNMQAR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ENMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQEFNARVCAPRL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCHHCCCHH
KDIAVAMGLDVKHLNDPQGAAACIAAIRLLAKDVGIPAGLLDLKVKEQDFDTLAANALKD
HHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
ACGFTNPIQATHEQIVAIFRAAM
HHCCCCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AASTFFIPPVNMIGSGCLDEAAKTMKQQGLRHALIVTDKVLNNIGVVAQVQQLLAVQQI
CCCEEECCCHHHHCCCHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHH
ESCVYDGTHPNPTTLNVKQGLALLQEHRCDCVVSLGGGSPHDCAKGIALVATNGGEIKDY
HHHHCCCCCCCCCEEEHHHHHHHHHHCCCCEEEECCCCCHHHHHCCEEEEEECCCCCCCC
EGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIKMAIVDKHVTPILSVNDPHLM
CCCCCCCCCCCCEEEEECCCCCHHHCEEEEEEECCCCEEEEEEECCCCCCEEECCCCHHC
AGMPKGLTAATGMDALTHAIEAYVSSAANPITDACALKAVTMIAESLRDAVADGSNMQAR
CCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHH
ENMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYDLPHGVCNAVLLPHVQEFNARVCAPRL
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHCCHHCCCHH
KDIAVAMGLDVKHLNDPQGAAACIAAIRLLAKDVGIPAGLLDLKVKEQDFDTLAANALKD
HHHHHHHCCCHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEECCCHHHHHHHHHHHH
ACGFTNPIQATHEQIVAIFRAAM
HHCCCCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8041620; 9278503; 7768815 [H]