Click here to switch to the map view.

The map label for this gene is tadA [H]

Identifier: 157371891

GI number: 157371891

Start: 4049263

End: 4049775

Strand: Reverse

Name: tadA [H]

Synonym: Spro_3656

Alternate gene names: 157371891

Gene position: 4049775-4049263 (Counterclockwise)

Preceding gene: 157371894

Following gene: 157371889

Centisome position: 74.32

GC content: 59.26

Gene sequence:

>513_bases
ATGACTGAATATAATGATGAGTACTGGATGCGTCAGGCATTGCGGTTGGCCCTGCGTGCGCAGGAAGAGGGCGAGGTGCC
GGTAGGGGCATTGCTGGTGCTGGATAATCAGGTGATTGGCGAGGGCTGGAACCGGCCGATTGGCCGCCACGATCCGACCG
CGCATGCGGAGATCATGGCGTTACGGCAGGGCGGGGCGGTGCTACAGAACTACCGTCTGCTGAATGCTACCCTATACGTG
ACTCTGGAACCCTGCGTGATGTGTGCAGGCGCTATGGTGCACAGCCGTATTCGTCGGTTGGTGTACGGCGCGGCCGATGT
TAAAACCGGTGCGGCAGGGTCGCTGGTGGATATTTTGCGCCACCCCGGCATGAATCATCAGGTGGAGATCCTGTCCGGCG
TGCTGGCCGAGGAGTGCGCCGCTACGCTGAGCAACTTTTTCCGCATGCGTCGTGAGCAGCAAAAGGCGTTGAAACAAGCG
CAGCGTACCGATGTCGATAACAAGCCGGAATAA

Upstream 100 bases:

>100_bases
CTGTAGGGGGCGAATATATTCGCCCCGGCTAACACGGGCGCAGCATGCAGCGCCCCTACTGTGTATAATGCCCGCCGCAA
AGTGCACGAGGAATGATGCA

Downstream 100 bases:

>100_bases
TCAGAAATTCAGTGCCAGTTCCGGCGTAACGGCCGGATAACCTTTCCCCTGGTCAGCCTGTTCGGCCGCTTCCTGTGCCG
CCTTTCTCTCTTTTTCCTGC

Product: zinc-binding CMP/dCMP deaminase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 170; Mature: 169

Protein sequence:

>170_residues
MTEYNDEYWMRQALRLALRAQEEGEVPVGALLVLDNQVIGEGWNRPIGRHDPTAHAEIMALRQGGAVLQNYRLLNATLYV
TLEPCVMCAGAMVHSRIRRLVYGAADVKTGAAGSLVDILRHPGMNHQVEILSGVLAEECAATLSNFFRMRREQQKALKQA
QRTDVDNKPE

Sequences:

>Translated_170_residues
MTEYNDEYWMRQALRLALRAQEEGEVPVGALLVLDNQVIGEGWNRPIGRHDPTAHAEIMALRQGGAVLQNYRLLNATLYV
TLEPCVMCAGAMVHSRIRRLVYGAADVKTGAAGSLVDILRHPGMNHQVEILSGVLAEECAATLSNFFRMRREQQKALKQA
QRTDVDNKPE
>Mature_169_residues
TEYNDEYWMRQALRLALRAQEEGEVPVGALLVLDNQVIGEGWNRPIGRHDPTAHAEIMALRQGGAVLQNYRLLNATLYVT
LEPCVMCAGAMVHSRIRRLVYGAADVKTGAAGSLVDILRHPGMNHQVEILSGVLAEECAATLSNFFRMRREQQKALKQAQ
RTDVDNKPE

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=151, Percent_Identity=35.0993377483444, Blast_Score=93, Evalue=1e-19,
Organism=Homo sapiens, GI19923945, Length=69, Percent_Identity=46.3768115942029, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI145693172, Length=162, Percent_Identity=74.6913580246914, Blast_Score=261, Evalue=2e-71,
Organism=Caenorhabditis elegans, GI17541138, Length=146, Percent_Identity=36.986301369863, Blast_Score=96, Evalue=7e-21,
Organism=Caenorhabditis elegans, GI17554608, Length=98, Percent_Identity=39.7959183673469, Blast_Score=79, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6322425, Length=168, Percent_Identity=30.952380952381, Blast_Score=72, Evalue=6e-14,
Organism=Drosophila melanogaster, GI21355527, Length=146, Percent_Identity=32.8767123287671, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 18967; Mature: 18836

Theoretical pI: Translated: 7.04; Mature: 7.04

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTEYNDEYWMRQALRLALRAQEEGEVPVGALLVLDNQVIGEGWNRPIGRHDPTAHAEIMA
CCCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCCCCCCCCCCCCHHHHHHH
LRQGGAVLQNYRLLNATLYVTLEPCVMCAGAMVHSRIRRLVYGAADVKTGAAGSLVDILR
HHHCCHHHHHHEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
HPGMNHQVEILSGVLAEECAATLSNFFRMRREQQKALKQAQRTDVDNKPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TEYNDEYWMRQALRLALRAQEEGEVPVGALLVLDNQVIGEGWNRPIGRHDPTAHAEIMA
CCCCHHHHHHHHHHHHHHHCCCCCCCEEEEEEECCHHHCCCCCCCCCCCCCCHHHHHHH
LRQGGAVLQNYRLLNATLYVTLEPCVMCAGAMVHSRIRRLVYGAADVKTGAAGSLVDILR
HHHCCHHHHHHEEEEEEEEEEECHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHH
HPGMNHQVEILSGVLAEECAATLSNFFRMRREQQKALKQAQRTDVDNKPE
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]