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The map label for this gene is ywbI [H]

Identifier: 157371883

GI number: 157371883

Start: 4035941

End: 4036864

Strand: Reverse

Name: ywbI [H]

Synonym: Spro_3648

Alternate gene names: 157371883

Gene position: 4036864-4035941 (Counterclockwise)

Preceding gene: 157371884

Following gene: 157371882

Centisome position: 74.09

GC content: 58.98

Gene sequence:

>924_bases
ATGATGACGCTACGCCAAATTCGCCACTTCATTGCGGTGGCGGAAACCGGGTCGATCTCCGCCGCCGCCCAGGCGGTGTT
TGTTTCCCAATCCTCGCTGACGCTGGCTATTCAGCAGTTGGAGACCGACATTGGCGTTCGGCTGTTTGATCGCCACGCCA
AGGGCATGAACCTGACGCATCAGGGCCATCAGTTTCTGCGCCAGTCTTACCTGATCCTCGCCACGGTGGATAACGCCAAG
CGCAGCCTGCAACTGGGTACCGAAAGCCTGACCGGCAAGCTGACCATTGGCGTGACCAGCCTGGTGGCCGGGTACTTTTT
GGTCGAACTGCTCAAGCGGTTTAAATCGGCCTATCCCAATGTCACCATTCAGATGATCGAAGATGAGCGTCCTTATATTG
AGCACCTGTTGGTGAGCGGGGAGATCGATATCGGCGTACTGATACTGTCGAATATTGAGGATCGTGATGCGTTACAGACC
GAAGTGCTGATGCACTCGCCTTATCGTCTGTGGTTACCGCCGCTGCATCCGTTGCTGGATCATGAAAGTATCGGGTTGGC
GGATGTGGCGAAGCTGCCGCTGATCCAGCTGAATGCCGACGAAATGGACGTGCATGCGCGGCGCATCTGGGCGCGTGCCG
GAGTGAAACCGGAGATCGCCATGAAAACCGGTTCGACGGAGGCGGTGCGCAGCCTGGTAGCGGCGGGCATGGGCGTCTCG
ATCCTACCGGACATGGCCTATCGCGCCTGGTCGCTGGAGGGCAACATGATTGAGGCCCGCAAGCTGGTGGATCTGCTGGA
GCCGCTCGACATCGGCCTGGCCTGGCGACGCGGCAGTGCGCGGCCGGAGCTGGTCACGCCTTTCCTCACCATTGCCCGTG
AGAATGGCAATATGCACGCTGCCGGACTGAAGCATTCGATTTAA

Upstream 100 bases:

>100_bases
TCTAAAAAAGCGAAGGCTGTCGCGTTTTTAATAGTTTTCCCGATCGCTTTGCGAACGACATCTACACTCAATCCAACTGT
TTTGATTGAGGTTGTGACCT

Downstream 100 bases:

>100_bases
TCGAACGCGGCGTTCAGTATTTAGAATTTGTTGGCTGCCTGATGCTCGCTTAGTCTGATTGAAACTAACTTATTCACATT
TGGTTAACGTTTTGGTCACT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MMTLRQIRHFIAVAETGSISAAAQAVFVSQSSLTLAIQQLETDIGVRLFDRHAKGMNLTHQGHQFLRQSYLILATVDNAK
RSLQLGTESLTGKLTIGVTSLVAGYFLVELLKRFKSAYPNVTIQMIEDERPYIEHLLVSGEIDIGVLILSNIEDRDALQT
EVLMHSPYRLWLPPLHPLLDHESIGLADVAKLPLIQLNADEMDVHARRIWARAGVKPEIAMKTGSTEAVRSLVAAGMGVS
ILPDMAYRAWSLEGNMIEARKLVDLLEPLDIGLAWRRGSARPELVTPFLTIARENGNMHAAGLKHSI

Sequences:

>Translated_307_residues
MMTLRQIRHFIAVAETGSISAAAQAVFVSQSSLTLAIQQLETDIGVRLFDRHAKGMNLTHQGHQFLRQSYLILATVDNAK
RSLQLGTESLTGKLTIGVTSLVAGYFLVELLKRFKSAYPNVTIQMIEDERPYIEHLLVSGEIDIGVLILSNIEDRDALQT
EVLMHSPYRLWLPPLHPLLDHESIGLADVAKLPLIQLNADEMDVHARRIWARAGVKPEIAMKTGSTEAVRSLVAAGMGVS
ILPDMAYRAWSLEGNMIEARKLVDLLEPLDIGLAWRRGSARPELVTPFLTIARENGNMHAAGLKHSI
>Mature_307_residues
MMTLRQIRHFIAVAETGSISAAAQAVFVSQSSLTLAIQQLETDIGVRLFDRHAKGMNLTHQGHQFLRQSYLILATVDNAK
RSLQLGTESLTGKLTIGVTSLVAGYFLVELLKRFKSAYPNVTIQMIEDERPYIEHLLVSGEIDIGVLILSNIEDRDALQT
EVLMHSPYRLWLPPLHPLLDHESIGLADVAKLPLIQLNADEMDVHARRIWARAGVKPEIAMKTGSTEAVRSLVAAGMGVS
ILPDMAYRAWSLEGNMIEARKLVDLLEPLDIGLAWRRGSARPELVTPFLTIARENGNMHAAGLKHSI

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787879, Length=251, Percent_Identity=33.8645418326693, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI157672245, Length=247, Percent_Identity=30.3643724696356, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1790399, Length=286, Percent_Identity=26.5734265734266, Blast_Score=94, Evalue=1e-20,
Organism=Escherichia coli, GI87081904, Length=193, Percent_Identity=32.6424870466321, Blast_Score=91, Evalue=1e-19,
Organism=Escherichia coli, GI1788296, Length=238, Percent_Identity=30.2521008403361, Blast_Score=89, Evalue=5e-19,
Organism=Escherichia coli, GI1788748, Length=312, Percent_Identity=24.3589743589744, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1788887, Length=300, Percent_Identity=26.3333333333333, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1790208, Length=309, Percent_Identity=27.1844660194175, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787601, Length=183, Percent_Identity=27.3224043715847, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787530, Length=258, Percent_Identity=25.5813953488372, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1787806, Length=294, Percent_Identity=28.5714285714286, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367136, Length=247, Percent_Identity=23.4817813765182, Blast_Score=78, Evalue=9e-16,
Organism=Escherichia coli, GI1790262, Length=310, Percent_Identity=25.8064516129032, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI87082132, Length=262, Percent_Identity=26.7175572519084, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1789204, Length=277, Percent_Identity=25.2707581227437, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786401, Length=260, Percent_Identity=23.4615384615385, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693105, Length=252, Percent_Identity=22.6190476190476, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1788626, Length=245, Percent_Identity=30.6122448979592, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1786713, Length=302, Percent_Identity=26.8211920529801, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI1788481, Length=256, Percent_Identity=26.5625, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1788297, Length=271, Percent_Identity=22.140221402214, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1789173, Length=144, Percent_Identity=28.4722222222222, Blast_Score=64, Evalue=1e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33965; Mature: 33965

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLRQIRHFIAVAETGSISAAAQAVFVSQSSLTLAIQQLETDIGVRLFDRHAKGMNLTH
CCCHHHHHHHHHHCCCCCCHHHHHEEEEECCHHHHHHHHHHHHHCHHEEHHCCCCCCCCH
QGHQFLRQSYLILATVDNAKRSLQLGTESLTGKLTIGVTSLVAGYFLVELLKRFKSAYPN
HHHHHHHCCEEEEEEECCCHHHHHCCCHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC
VTIQMIEDERPYIEHLLVSGEIDIGVLILSNIEDRDALQTEVLMHSPYRLWLPPLHPLLD
EEEEEEECCCHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCHHHC
HESIGLADVAKLPLIQLNADEMDVHARRIWARAGVKPEIAMKTGSTEAVRSLVAAGMGVS
CCCCCHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCH
ILPDMAYRAWSLEGNMIEARKLVDLLEPLDIGLAWRRGSARPELVTPFLTIARENGNMHA
HHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHEEEECCCCEEE
AGLKHSI
CCCCCCC
>Mature Secondary Structure
MMTLRQIRHFIAVAETGSISAAAQAVFVSQSSLTLAIQQLETDIGVRLFDRHAKGMNLTH
CCCHHHHHHHHHHCCCCCCHHHHHEEEEECCHHHHHHHHHHHHHCHHEEHHCCCCCCCCH
QGHQFLRQSYLILATVDNAKRSLQLGTESLTGKLTIGVTSLVAGYFLVELLKRFKSAYPN
HHHHHHHCCEEEEEEECCCHHHHHCCCHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHCCC
VTIQMIEDERPYIEHLLVSGEIDIGVLILSNIEDRDALQTEVLMHSPYRLWLPPLHPLLD
EEEEEEECCCHHHHHHEECCCCCEEEEEECCCCCHHHHHHHHHHCCCCEEECCCCCHHHC
HESIGLADVAKLPLIQLNADEMDVHARRIWARAGVKPEIAMKTGSTEAVRSLVAAGMGVS
CCCCCHHHHHHCCEEEECCCHHHHHHHHHHHHCCCCCEEEEECCCHHHHHHHHHHCCCCH
ILPDMAYRAWSLEGNMIEARKLVDLLEPLDIGLAWRRGSARPELVTPFLTIARENGNMHA
HHHHHHHHEEECCCCCHHHHHHHHHHHHHCCCEEECCCCCCCCHHHHHHEEEECCCCEEE
AGLKHSI
CCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377 [H]