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The map label for this gene is engA

Identifier: 157371840

GI number: 157371840

Start: 3983487

End: 3984971

Strand: Reverse

Name: engA

Synonym: Spro_3605

Alternate gene names: 157371840

Gene position: 3984971-3983487 (Counterclockwise)

Preceding gene: 157371841

Following gene: 157371839

Centisome position: 73.13

GC content: 56.7

Gene sequence:

>1485_bases
ATGATACCTGTCGTCGCGCTAGTAGGGCGCCCGAATGTGGGTAAATCCACCTTGTTTAACCGTTTAACCCATACGCGCGA
TGCGCTGGTGGCGGATTTCCCCGGGCTAACGCGAGACCGCAAGTATGGTCGTGCTGAGGTTGAGGGTAATGAATTTATTA
TCGTCGATACCGGGGGCATTGACGGCACCGAAGATGGCGTTGAAACACGCATGGCCGGTCAGTCGCTGCTGGCGATCGAA
GAAGCAGACATCGTGCTGTTTATGGTCGATGCTCGCGCCGGTCTGATGCCGGCCGATCTGGGCATTGCCCAGCATCTGCG
CAACCGTCAGAAAGCCACCTTCCTGGTCGCCAACAAAACCGACGGTATGGATCCAGACATGGCCGCCGCCGATTTCTATT
CGCTGGGCCTGGGCGACGTGCATCCGATCGCGGCTTCCCACGGTCGTGGCGTAGCGCAGTTGATCGAGCACGTACTGGTG
CCGTTTGTCGGTGAAAAGCCGGAAGAAGTCGAGCTGACCGAAGAAGAGGCTAATGCCGCTTATTGGGCCGAGCAAGAAGG
TGAAACCCTCGAAGGCGCAGAAGAAGAGCCGGAAGACGACTTCAACCCGCAGGATCTGCCAATCAAGCTGGCTATCGTGG
GTCGTCCTAACGTAGGTAAGTCCACACTGACTAACCGCATTCTCGGCGAAGATCGTGTCGTGGTCTACGACATGCCGGGC
ACGACCCGTGACAGTATCTATATCCCGATGGTCCGCGACGAGCGCGAATACGTGCTGATCGATACCGCCGGGGTACGTAA
GCGCGGCAAAGTTACGGAAACCGTAGAGAAGTTCTCGGTAATCAAAACCCTGCAGGCGATTGAAGACGCCAACGTGGTGT
TGCTGGTCGTGGATGCACGCGAAGGCATTTCCGATCAGGATCTCTCGCTGCTCGGCTTTATCCTCAATAGTGGGCGCTCA
CTGGTGATTGTCGTCAACAAGTGGGACGGCATGAGCGAGGAAGATCGCGATCACGTGAAAGAGATGCTCGATCTGCGTCT
GGGCTTTGTCGATTTCGCCCGCATTCACTTTATCTCTGCCCTGCATGGTAGCGGCGTTGGCAACTTGTTCGTGTCGGTAC
TGGAAGCTTACGAGTGTGCGACCCGCCGCGTGAACACCTCAATGCTGACCAAAATCATGCAGATGGCTGCCGACGATCAC
CAACCGCCGTTGGTACGTGGCCGCCGCGTGAAGCTGAAATATGCGCACGCCGGTGGGTATAACCCGCCGATTGTGGTGAT
CCACGGCAACCAGGTGACCGATCTGTCCGATTCGTACAAACGCTACCTGATGAACTACTTCCGTCGTTCTCTGAAGGTGA
TGGGTACGCCGATCCGCATCCAGTTCAAAGAGGGTGAGAACCCGTTCGCCGGTAAGCGCAACCTGCTGACGCCGAACCAG
ATGCGCAAGCGTAAACGTCTGATGAGCCACCTGAAGAAAGGCTAA

Upstream 100 bases:

>100_bases
CCTGAATGTTCAGGGGCCGTTTCGTATTTTTATAAGCTGCACTCCTGGTGTCTATCCAAAGTGTAGTAACGCTTTGATTA
TTAAGTAATGAGGCTTCACA

Downstream 100 bases:

>100_bases
TCATAAGAATGAGGGGCGCGGTATCACTACCGCGCCCCTTTTTTATTGGATCGAAATCGTTTTATTATCTGACTATTACC
GCCGTTAGCCTGAAGGAACA

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA

Number of amino acids: Translated: 494; Mature: 494

Protein sequence:

>494_residues
MIPVVALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGNEFIIVDTGGIDGTEDGVETRMAGQSLLAIE
EADIVLFMVDARAGLMPADLGIAQHLRNRQKATFLVANKTDGMDPDMAAADFYSLGLGDVHPIAASHGRGVAQLIEHVLV
PFVGEKPEEVELTEEEANAAYWAEQEGETLEGAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
TTRDSIYIPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVVDAREGISDQDLSLLGFILNSGRS
LVIVVNKWDGMSEEDRDHVKEMLDLRLGFVDFARIHFISALHGSGVGNLFVSVLEAYECATRRVNTSMLTKIMQMAADDH
QPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNLLTPNQ
MRKRKRLMSHLKKG

Sequences:

>Translated_494_residues
MIPVVALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGNEFIIVDTGGIDGTEDGVETRMAGQSLLAIE
EADIVLFMVDARAGLMPADLGIAQHLRNRQKATFLVANKTDGMDPDMAAADFYSLGLGDVHPIAASHGRGVAQLIEHVLV
PFVGEKPEEVELTEEEANAAYWAEQEGETLEGAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
TTRDSIYIPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVVDAREGISDQDLSLLGFILNSGRS
LVIVVNKWDGMSEEDRDHVKEMLDLRLGFVDFARIHFISALHGSGVGNLFVSVLEAYECATRRVNTSMLTKIMQMAADDH
QPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNLLTPNQ
MRKRKRLMSHLKKG
>Mature_494_residues
MIPVVALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGNEFIIVDTGGIDGTEDGVETRMAGQSLLAIE
EADIVLFMVDARAGLMPADLGIAQHLRNRQKATFLVANKTDGMDPDMAAADFYSLGLGDVHPIAASHGRGVAQLIEHVLV
PFVGEKPEEVELTEEEANAAYWAEQEGETLEGAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
TTRDSIYIPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVVDAREGISDQDLSLLGFILNSGRS
LVIVVNKWDGMSEEDRDHVKEMLDLRLGFVDFARIHFISALHGSGVGNLFVSVLEAYECATRRVNTSMLTKIMQMAADDH
QPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNLLTPNQ
MRKRKRLMSHLKKG

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain

Homologues:

Organism=Escherichia coli, GI87082120, Length=493, Percent_Identity=81.3387423935091, Blast_Score=811, Evalue=0.0,
Organism=Escherichia coli, GI2367268, Length=91, Percent_Identity=39.5604395604396, Blast_Score=65, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6323665, Length=144, Percent_Identity=32.6388888888889, Blast_Score=73, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DER_SERP5 (A8GHW1)

Other databases:

- EMBL:   CP000826
- RefSeq:   YP_001479829.1
- ProteinModelPortal:   A8GHW1
- SMR:   A8GHW1
- STRING:   A8GHW1
- GeneID:   5605855
- GenomeReviews:   CP000826_GR
- KEGG:   spe:Spro_3605
- eggNOG:   COG1160
- HOGENOM:   HBG592135
- OMA:   TRDRTYQ
- ProtClustDB:   PRK00093
- BioCyc:   SPRO399741:SPRO_3605-MONOMER
- GO:   GO:0005622
- HAMAP:   MF_00195
- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225
- Gene3D:   G3DSA:3.30.300.20
- PIRSF:   PIRSF006485
- PRINTS:   PR00326
- TIGRFAMs:   TIGR03594
- TIGRFAMs:   TIGR00231

Pfam domain/function: PF01926 MMR_HSR1

EC number: NA

Molecular weight: Translated: 54878; Mature: 54878

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGNEFIIVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEECCCC
DGTEDGVETRMAGQSLLAIEEADIVLFMVDARAGLMPADLGIAQHLRNRQKATFLVANKT
CCCCCCHHHHHCCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECC
DGMDPDMAAADFYSLGLGDVHPIAASHGRGVAQLIEHVLVPFVGEKPEEVELTEEEANAA
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCE
YWAEQEGETLEGAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
EEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCC
TTRDSIYIPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVVDAR
CCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
EGISDQDLSLLGFILNSGRSLVIVVNKWDGMSEEDRDHVKEMLDLRLGFVDFARIHFISA
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LHGSGVGNLFVSVLEAYECATRRVNTSMLTKIMQMAADDHQPPLVRGRRVKLKYAHAGGY
HHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC
NPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNLLTPNQ
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHH
MRKRKRLMSHLKKG
HHHHHHHHHHHHCC
>Mature Secondary Structure
MIPVVALVGRPNVGKSTLFNRLTHTRDALVADFPGLTRDRKYGRAEVEGNEFIIVDTGGI
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCEEEEEECCCC
DGTEDGVETRMAGQSLLAIEEADIVLFMVDARAGLMPADLGIAQHLRNRQKATFLVANKT
CCCCCCHHHHHCCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHHCCCCCEEEEEEECC
DGMDPDMAAADFYSLGLGDVHPIAASHGRGVAQLIEHVLVPFVGEKPEEVELTEEEANAA
CCCCCCHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHCCCE
YWAEQEGETLEGAEEEPEDDFNPQDLPIKLAIVGRPNVGKSTLTNRILGEDRVVVYDMPG
EEECCCCCCCCCCCCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCCCEEEEECCC
TTRDSIYIPMVRDEREYVLIDTAGVRKRGKVTETVEKFSVIKTLQAIEDANVVLLVVDAR
CCCCCEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHHHHHHHCCCCEEEEEEECC
EGISDQDLSLLGFILNSGRSLVIVVNKWDGMSEEDRDHVKEMLDLRLGFVDFARIHFISA
CCCCCCHHHHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCHHHHHHHHHHHH
LHGSGVGNLFVSVLEAYECATRRVNTSMLTKIMQMAADDHQPPLVRGRRVKLKYAHAGGY
HHCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEECCCC
NPPIVVIHGNQVTDLSDSYKRYLMNYFRRSLKVMGTPIRIQFKEGENPFAGKRNLLTPNQ
CCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCCCHHH
MRKRKRLMSHLKKG
HHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA