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The map label for this gene is sotB [H]

Identifier: 157371829

GI number: 157371829

Start: 3969571

End: 3970752

Strand: Reverse

Name: sotB [H]

Synonym: Spro_3594

Alternate gene names: 157371829

Gene position: 3970752-3969571 (Counterclockwise)

Preceding gene: 157371830

Following gene: 157371828

Centisome position: 72.87

GC content: 53.89

Gene sequence:

>1182_bases
ATGCCCAACTCAACTTTGCGGATATGGTGTGCGGTCAGTGTGTTGTGTGTGGCTTCGTTCACTATGGTGACCTCCGAATT
CGCTCCCATTGGCTTGTTATCGCAGCTATCAAACGACCTGAATCAAGATCCATCAACCATTGGGCTGACAGTAACGTTAT
ATGCATGGATCGGTGCTGCCAGCGGCCTATTATCAAACTGGTTAAACCGTTGGATCCCGCGCAAGGCACTGTTGATCGCA
TTGATGTTTATACTGGCCGTCTCTAACGGCCTGGTGGCGTTATCCCCCGAATTCTCTATGTTGCTCGGTGCCCGCGCCGT
CGGTGCATTGGCCCATGGCATGTTCTGGGCCATCGTGGCTGCCACTGCCGCGCATATTGTGCCGGCACATCGAATGGGGC
TCGCCACCTCGATTGTTTTGGGGGGCATCACCATTGCTACGGTTATGGGCGTCCCGCTGATCAACCTGGTTGGCCAATAC
GATGGCTGGCGCACGGCCTTTGTATGCCTGGCCCTGCTGTGTGTCGTCAGTGCCGGTGCTATGGTGTTGGTGCTACCTAC
TATGCACATTCATTCTCTAGCCAAAGGTGTCGGATTCGCGGTGGTACTGCGCCGTAAGGATCTCTTGATTACGTATGTCA
TTACCGGGCTGACGGCGGCCGCGCATTTTGGTGCCTATACCTTTGTCGAACCTTTTATTGGCCAGGTACCGGGCATGACG
TCGTACTTGATTGCTGCCTTGTTGTTTGCCTTTGGGGCAGCCGGTTTCCTGGGTAACTTGCTGAGTGCACTCTTTATCGA
TCGCTACTTAAAGGTTTTCATTCTGGTGGCGTTGATGGTGATGGCGCTGGCCTTGGTGACTTTAGGCATCTACGGCCCGC
CACTGGGTATTGTGGCCGTAGTGATCTTGCTGGTGATTTGGGGCGTGGCTATTTCCGCTTTGTTTACAGGTCTGCAGACC
TGGGTATTGAGGATTGCCGGTGATCACACTGTACCGGCAACCGCGATCCATACGGCTGTATTGAACAGCGCGATTGGTCT
GGGTGTGATTATTGGCGGGGAGGCGCTGAGTGTAGCTGGCTTTAAAGGTGCCATGTTGTCAGCCGGTGTAGTGGTTGTCC
CTGCCATTATTCTGATGATGGCCTCGATTCCACGATCTCGAACAGAACCCGTTTCCTCGTAA

Upstream 100 bases:

>100_bases
ATCGCCAAGCACCACTTTTTTGTGGCATGGTAGCCGCTACGAGTCAGGGTTTCCTCGCAGGAGGGCTCACAATGGCTCCG
TCATAAACAGGAATGGACAG

Downstream 100 bases:

>100_bases
TCGCGCCTAAATTACAGTACGTTATATTTCTGCAACGGCGGTTAGCTAGACCGCCAAGTTTTGAAAAATCCGCCGGAGGT
TTGATGACGACATTGCCAAC

Product: major facilitator transporter

Products: arabinose [Periplasm]; Proton [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 393; Mature: 392

Protein sequence:

>393_residues
MPNSTLRIWCAVSVLCVASFTMVTSEFAPIGLLSQLSNDLNQDPSTIGLTVTLYAWIGAASGLLSNWLNRWIPRKALLIA
LMFILAVSNGLVALSPEFSMLLGARAVGALAHGMFWAIVAATAAHIVPAHRMGLATSIVLGGITIATVMGVPLINLVGQY
DGWRTAFVCLALLCVVSAGAMVLVLPTMHIHSLAKGVGFAVVLRRKDLLITYVITGLTAAAHFGAYTFVEPFIGQVPGMT
SYLIAALLFAFGAAGFLGNLLSALFIDRYLKVFILVALMVMALALVTLGIYGPPLGIVAVVILLVIWGVAISALFTGLQT
WVLRIAGDHTVPATAIHTAVLNSAIGLGVIIGGEALSVAGFKGAMLSAGVVVVPAIILMMASIPRSRTEPVSS

Sequences:

>Translated_393_residues
MPNSTLRIWCAVSVLCVASFTMVTSEFAPIGLLSQLSNDLNQDPSTIGLTVTLYAWIGAASGLLSNWLNRWIPRKALLIA
LMFILAVSNGLVALSPEFSMLLGARAVGALAHGMFWAIVAATAAHIVPAHRMGLATSIVLGGITIATVMGVPLINLVGQY
DGWRTAFVCLALLCVVSAGAMVLVLPTMHIHSLAKGVGFAVVLRRKDLLITYVITGLTAAAHFGAYTFVEPFIGQVPGMT
SYLIAALLFAFGAAGFLGNLLSALFIDRYLKVFILVALMVMALALVTLGIYGPPLGIVAVVILLVIWGVAISALFTGLQT
WVLRIAGDHTVPATAIHTAVLNSAIGLGVIIGGEALSVAGFKGAMLSAGVVVVPAIILMMASIPRSRTEPVSS
>Mature_392_residues
PNSTLRIWCAVSVLCVASFTMVTSEFAPIGLLSQLSNDLNQDPSTIGLTVTLYAWIGAASGLLSNWLNRWIPRKALLIAL
MFILAVSNGLVALSPEFSMLLGARAVGALAHGMFWAIVAATAAHIVPAHRMGLATSIVLGGITIATVMGVPLINLVGQYD
GWRTAFVCLALLCVVSAGAMVLVLPTMHIHSLAKGVGFAVVLRRKDLLITYVITGLTAAAHFGAYTFVEPFIGQVPGMTS
YLIAALLFAFGAAGFLGNLLSALFIDRYLKVFILVALMVMALALVTLGIYGPPLGIVAVVILLVIWGVAISALFTGLQTW
VLRIAGDHTVPATAIHTAVLNSAIGLGVIIGGEALSVAGFKGAMLSAGVVVVPAIILMMASIPRSRTEPVSS

Specific function: Involved in the efflux of sugars. The physiological role may be the reduction of the intracellular concentration of toxic sugars or sugar metabolites [H]

COG id: COG2814

COG function: function code G; Arabinose efflux permease

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. SotB (TC 2.A.1.2) family [H]

Homologues:

Organism=Escherichia coli, GI1787808, Length=392, Percent_Identity=30.6122448979592, Blast_Score=150, Evalue=2e-37,
Organism=Escherichia coli, GI145693198, Length=382, Percent_Identity=27.2251308900524, Blast_Score=130, Evalue=2e-31,
Organism=Escherichia coli, GI1787947, Length=329, Percent_Identity=28.8753799392097, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1786595, Length=257, Percent_Identity=22.1789883268482, Blast_Score=67, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 40986; Mature: 40855

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPNSTLRIWCAVSVLCVASFTMVTSEFAPIGLLSQLSNDLNQDPSTIGLTVTLYAWIGAA
CCCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SGLLSNWLNRWIPRKALLIALMFILAVSNGLVALSPEFSMLLGARAVGALAHGMFWAIVA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
ATAAHIVPAHRMGLATSIVLGGITIATVMGVPLINLVGQYDGWRTAFVCLALLCVVSAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
MVLVLPTMHIHSLAKGVGFAVVLRRKDLLITYVITGLTAAAHFGAYTFVEPFIGQVPGMT
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SYLIAALLFAFGAAGFLGNLLSALFIDRYLKVFILVALMVMALALVTLGIYGPPLGIVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VILLVIWGVAISALFTGLQTWVLRIAGDHTVPATAIHTAVLNSAIGLGVIIGGEALSVAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCHHHHCC
FKGAMLSAGVVVVPAIILMMASIPRSRTEPVSS
CCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
PNSTLRIWCAVSVLCVASFTMVTSEFAPIGLLSQLSNDLNQDPSTIGLTVTLYAWIGAA
CCCCEEHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
SGLLSNWLNRWIPRKALLIALMFILAVSNGLVALSPEFSMLLGARAVGALAHGMFWAIVA
HHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCEEECCHHHHHHHHHHHHHHHHHHHHHHHH
ATAAHIVPAHRMGLATSIVLGGITIATVMGVPLINLVGQYDGWRTAFVCLALLCVVSAGA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
MVLVLPTMHIHSLAKGVGFAVVLRRKDLLITYVITGLTAAAHFGAYTFVEPFIGQVPGMT
CEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
SYLIAALLFAFGAAGFLGNLLSALFIDRYLKVFILVALMVMALALVTLGIYGPPLGIVAV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHH
VILLVIWGVAISALFTGLQTWVLRIAGDHTVPATAIHTAVLNSAIGLGVIIGGEALSVAG
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHEEEECCCHHHHCC
FKGAMLSAGVVVVPAIILMMASIPRSRTEPVSS
CCHHHHHCCHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: arabinose [Cytoplasm]; Proton [Periplasm] [C]

Specific reaction: arabinose [Cytoplasm] + Proton [Periplasm] = arabinose [Periplasm] + Proton [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA