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The map label for this gene is srlR [H]

Identifier: 157371809

GI number: 157371809

Start: 3950445

End: 3951218

Strand: Direct

Name: srlR [H]

Synonym: Spro_3574

Alternate gene names: 157371809

Gene position: 3950445-3951218 (Clockwise)

Preceding gene: 157371808

Following gene: 157371810

Centisome position: 72.5

GC content: 54.26

Gene sequence:

>774_bases
ATGAAACCAAAGCAGCGACAGGCCGCTATCCTTGAATATCTGCAGCGACATGGCAAAACGGCAGTGGATGCCCTGGCGGT
ACATTTCGCCACCACCGGCACCACCATACGTAAAGATCTCACCCTCTTGGAAGACGAAGGCGAGGTGATCCGCACCTACG
GCGGCGTAGTGCTCAGCCGCGACGATGGCGACCAGCCCATCGACCGAAAAACGCATATCAATACCGAAAAGAAACGCCAG
ATCGCCTACGCCGCCATCAAGTTGATCAACGACGGTGATTCGCTGATATTCGATGCCGGCAGTACGGTACTGCAAATGGT
CCCGCATCTGGCGCAGTTCAATAACATCACGGTAATGACCAACAGCCTGCACATCGTCAATGCGCTGGTGGAGCTGGATA
ACGACCAGACCATCCTGATGCCCGGCGGCACTTATCGCAAAAAATCGGCGTCCTTCCACGGCAGTCTGGCGGAGTCTGCT
TTCCAGCAATTCAGCTTTGATAAGCTGTTTATCGGCGCAGACGGCGTGGATCTCAATGCCGGTGTCACCACCTTTAACGA
AGTGCATAACGTCAGCAAGGCGATGTGCGAAGCCGCCAGCCGCATTATCCTGCTGGTGGACTCGTCAAAATTCGGCCGCA
AAAGCCCCAATGTGGTTTGCGATCTGAGCGCCGTCGATACGCTGATCACCGATAAAAACATCAACCCGGATTATCTCGCC
GCGCTGCAAGCGAAAGGCATCAATATCCTTCTGGTAGGAGATTCTGATGAGTAA

Upstream 100 bases:

>100_bases
TTGCCCCTAAATCATGATATTTTCACATTAAAAGACATTACCTTTCATATTGAATTATTCATTAAAGGGAAATGCTCAAC
TCTTGTGAACAGGACGGGCT

Downstream 100 bases:

>100_bases
TAGTGCCGCCCTGCTGGCCTTTGCCCGCGAAACGCTGGAAATTGAGCTGGCCGAAGCACAACGCCTGCTGGCACGACTGG
ACGACAATTTCGTCTGTGCC

Product: DNA-binding transcriptional repressor SrlR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 257; Mature: 257

Protein sequence:

>257_residues
MKPKQRQAAILEYLQRHGKTAVDALAVHFATTGTTIRKDLTLLEDEGEVIRTYGGVVLSRDDGDQPIDRKTHINTEKKRQ
IAYAAIKLINDGDSLIFDAGSTVLQMVPHLAQFNNITVMTNSLHIVNALVELDNDQTILMPGGTYRKKSASFHGSLAESA
FQQFSFDKLFIGADGVDLNAGVTTFNEVHNVSKAMCEAASRIILLVDSSKFGRKSPNVVCDLSAVDTLITDKNINPDYLA
ALQAKGINILLVGDSDE

Sequences:

>Translated_257_residues
MKPKQRQAAILEYLQRHGKTAVDALAVHFATTGTTIRKDLTLLEDEGEVIRTYGGVVLSRDDGDQPIDRKTHINTEKKRQ
IAYAAIKLINDGDSLIFDAGSTVLQMVPHLAQFNNITVMTNSLHIVNALVELDNDQTILMPGGTYRKKSASFHGSLAESA
FQQFSFDKLFIGADGVDLNAGVTTFNEVHNVSKAMCEAASRIILLVDSSKFGRKSPNVVCDLSAVDTLITDKNINPDYLA
ALQAKGINILLVGDSDE
>Mature_257_residues
MKPKQRQAAILEYLQRHGKTAVDALAVHFATTGTTIRKDLTLLEDEGEVIRTYGGVVLSRDDGDQPIDRKTHINTEKKRQ
IAYAAIKLINDGDSLIFDAGSTVLQMVPHLAQFNNITVMTNSLHIVNALVELDNDQTILMPGGTYRKKSASFHGSLAESA
FQQFSFDKLFIGADGVDLNAGVTTFNEVHNVSKAMCEAASRIILLVDSSKFGRKSPNVVCDLSAVDTLITDKNINPDYLA
ALQAKGINILLVGDSDE

Specific function: Unknown

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789059, Length=257, Percent_Identity=70.8171206225681, Blast_Score=385, Evalue=1e-108,
Organism=Escherichia coli, GI1789519, Length=256, Percent_Identity=36.328125, Blast_Score=182, Evalue=2e-47,
Organism=Escherichia coli, GI1788069, Length=254, Percent_Identity=29.9212598425197, Blast_Score=117, Evalue=7e-28,
Organism=Escherichia coli, GI1789829, Length=245, Percent_Identity=28.9795918367347, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI226510968, Length=253, Percent_Identity=28.4584980237154, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790635, Length=254, Percent_Identity=27.5590551181102, Blast_Score=98, Evalue=5e-22,
Organism=Escherichia coli, GI1787540, Length=250, Percent_Identity=31.2, Blast_Score=97, Evalue=1e-21,
Organism=Escherichia coli, GI1790753, Length=251, Percent_Identity=29.0836653386454, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI87082344, Length=249, Percent_Identity=26.9076305220884, Blast_Score=84, Evalue=7e-18,
Organism=Escherichia coli, GI1789170, Length=232, Percent_Identity=27.5862068965517, Blast_Score=83, Evalue=2e-17,
Organism=Escherichia coli, GI1787063, Length=250, Percent_Identity=26.8, Blast_Score=78, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28018; Mature: 28018

Theoretical pI: Translated: 5.89; Mature: 5.89

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPKQRQAAILEYLQRHGKTAVDALAVHFATTGTTIRKDLTLLEDEGEVIRTYGGVVLSR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHCCEEECCCCCEEEEECCEEEEC
DDGDQPIDRKTHINTEKKRQIAYAAIKLINDGDSLIFDAGSTVLQMVPHLAQFNNITVMT
CCCCCCCCCCCCCCCHHHHHHEEHEEEEECCCCEEEEECCHHHHHHHHHHHHCCCEEEEE
NSLHIVNALVELDNDQTILMPGGTYRKKSASFHGSLAESAFQQFSFDKLFIGADGVDLNA
CCHHEEEHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCC
GVTTFNEVHNVSKAMCEAASRIILLVDSSKFGRKSPNVVCDLSAVDTLITDKNINPDYLA
CCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHH
ALQAKGINILLVGDSDE
HHHHCCEEEEEEECCCC
>Mature Secondary Structure
MKPKQRQAAILEYLQRHGKTAVDALAVHFATTGTTIRKDLTLLEDEGEVIRTYGGVVLSR
CCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCHHHCCEEECCCCCEEEEECCEEEEC
DDGDQPIDRKTHINTEKKRQIAYAAIKLINDGDSLIFDAGSTVLQMVPHLAQFNNITVMT
CCCCCCCCCCCCCCCHHHHHHEEHEEEEECCCCEEEEECCHHHHHHHHHHHHCCCEEEEE
NSLHIVNALVELDNDQTILMPGGTYRKKSASFHGSLAESAFQQFSFDKLFIGADGVDLNA
CCHHEEEHHHCCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHCCCCEEEEECCCCCCCC
GVTTFNEVHNVSKAMCEAASRIILLVDSSKFGRKSPNVVCDLSAVDTLITDKNINPDYLA
CCCHHHHHHHHHHHHHHHHCEEEEEEECCCCCCCCCCEEEEHHHHHHHHCCCCCCHHHHH
ALQAKGINILLVGDSDE
HHHHCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3062173; 9278503; 9205837 [H]