Click here to switch to the map view.

The map label for this gene is baeS [H]

Identifier: 157371791

GI number: 157371791

Start: 3933180

End: 3934562

Strand: Direct

Name: baeS [H]

Synonym: Spro_3556

Alternate gene names: 157371791

Gene position: 3933180-3934562 (Clockwise)

Preceding gene: 157371790

Following gene: 157371792

Centisome position: 72.18

GC content: 58.28

Gene sequence:

>1383_bases
ATGAAAATAGGCATTACCGGTAAACTGTTCATGGCGATTTTCGCCACCTGCATGCTGGTGTTAATCACCATGCACTGGGG
TGTGCGTGTCAGCTTCGAACGCGGGTTTATCGACTACATCAAGAACAGTAACGAGCAGCGCATCAACATGCTGAGTGAAG
CGCTGGAAGAACAGTACAGCCACCACGGCAACTGGGTCTTTCTGCGCAATAACGATCAGGTGGTTTACCAGATCATGCGT
TCGTTCGAACAAAACAGCGACAGCAGCCACAATCTGCCGCCCAAGGGCTGGCGTACCCAGTTCTGGGTGGTGGACAGCCA
GTTTAACCGGCTGGTGGGGCATTCCGGCCCGCTGCCAAAGGAAGGCCCGCGTCATCCCATCCGCTACAACAATGAAATTG
TCGGCTGGGTGCTCACCACCCCGGTAGAGAGGCTGACGCGCAATACCGACATCAACTTCGACCAACAGCAAAGACGCACC
AGCTGGATGATTGTCGCCCTCTCCACCCTGTTAGCTGCGGCGGTGACCTGGCTGATGTCGCGCGGACTACTGGCGCCGGT
CAAACGCCTGGTAGCGGGTACCCATCGGCTGGCGGCGGGGGATTTCAGCACCCGCGTGGCGGTCAGCAGCCAGGATGAAC
TGGGGCGACTGGCGCTGGACTTTAACCAGCTTGCCACCTCACTGGAAAAAAATGAGCAGATGCGACGCGCCGTGATGGCC
GACGTCTCGCACGAATTACGCACCCCGCTGGCGGTGTTGCGCGGCGAACTCGAAGCCTTGCAAGATGGCGTGCGTCAGCC
CACCCCGGCCTCACTCAGCTCACTGCTGGCGGAAGTCGCCACCCTGACCAAGCTGGTCGATGACCTGCATCAACTGTCGT
TATCCGATCTCGGCGCGCTCGCCTACCGTAAATCACCGCTCGACTGTGTGCACCTGCTGCAAGTTGCGGTCGCCAGCTTC
CGCGACCGGTTCCACGCTAAAGGGCTGGAGATCGTGACACTGCTACCAGAGCAGGCACCGCTGTTTGGCGATCCCGACAG
GCTTAACCAACTGTTTAATAACCTGCTGGAAAACAGCCTGCGTTATACCGATGCCGAGGGTAAGCTGGAGATCGGCGCAG
AATCGTTGCCGGGCCGCCTGCTAATCTATTGGCAGGACAGCGCACCGGGCGTCAATGACGAGCAACTGGCACTCATTTTT
GAACGCTTCTACCGTACCGAAGGTTCGCGTAATCGCGCCAGCGGCGGCTCCGGACTGGGGCTATCGATCTGTCAAAACAT
AGTGGAAGCACACAACGGGAAGATCTACGCACAGCACTCGCCTTTGGGCGGCGTGCGGATTACTGTAGAATTCGCCACCC
CGGTAATGAATAAGGCGTCATGA

Upstream 100 bases:

>100_bases
TCGCCCTGCCCGCGTTGGCCTTCGCCCGCGTCCCGGCTGATACCACCACTAACCGCACGCTGACCAAAGAGCCGGGCACA
GGCTCCACGAGGTTGCAACA

Downstream 100 bases:

>100_bases
TGGAAACCCAGAACCAGCCGTTGCAAATTATGATTGTTGAAGATGAACCCAAGCTGGGCCAACTGCTGGTGGACTACCTG
CAGGCTGCGGGATACGCCAC

Product: signal transduction histidine-protein kinase BaeS

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MKIGITGKLFMAIFATCMLVLITMHWGVRVSFERGFIDYIKNSNEQRINMLSEALEEQYSHHGNWVFLRNNDQVVYQIMR
SFEQNSDSSHNLPPKGWRTQFWVVDSQFNRLVGHSGPLPKEGPRHPIRYNNEIVGWVLTTPVERLTRNTDINFDQQQRRT
SWMIVALSTLLAAAVTWLMSRGLLAPVKRLVAGTHRLAAGDFSTRVAVSSQDELGRLALDFNQLATSLEKNEQMRRAVMA
DVSHELRTPLAVLRGELEALQDGVRQPTPASLSSLLAEVATLTKLVDDLHQLSLSDLGALAYRKSPLDCVHLLQVAVASF
RDRFHAKGLEIVTLLPEQAPLFGDPDRLNQLFNNLLENSLRYTDAEGKLEIGAESLPGRLLIYWQDSAPGVNDEQLALIF
ERFYRTEGSRNRASGGSGLGLSICQNIVEAHNGKIYAQHSPLGGVRITVEFATPVMNKAS

Sequences:

>Translated_460_residues
MKIGITGKLFMAIFATCMLVLITMHWGVRVSFERGFIDYIKNSNEQRINMLSEALEEQYSHHGNWVFLRNNDQVVYQIMR
SFEQNSDSSHNLPPKGWRTQFWVVDSQFNRLVGHSGPLPKEGPRHPIRYNNEIVGWVLTTPVERLTRNTDINFDQQQRRT
SWMIVALSTLLAAAVTWLMSRGLLAPVKRLVAGTHRLAAGDFSTRVAVSSQDELGRLALDFNQLATSLEKNEQMRRAVMA
DVSHELRTPLAVLRGELEALQDGVRQPTPASLSSLLAEVATLTKLVDDLHQLSLSDLGALAYRKSPLDCVHLLQVAVASF
RDRFHAKGLEIVTLLPEQAPLFGDPDRLNQLFNNLLENSLRYTDAEGKLEIGAESLPGRLLIYWQDSAPGVNDEQLALIF
ERFYRTEGSRNRASGGSGLGLSICQNIVEAHNGKIYAQHSPLGGVRITVEFATPVMNKAS
>Mature_460_residues
MKIGITGKLFMAIFATCMLVLITMHWGVRVSFERGFIDYIKNSNEQRINMLSEALEEQYSHHGNWVFLRNNDQVVYQIMR
SFEQNSDSSHNLPPKGWRTQFWVVDSQFNRLVGHSGPLPKEGPRHPIRYNNEIVGWVLTTPVERLTRNTDINFDQQQRRT
SWMIVALSTLLAAAVTWLMSRGLLAPVKRLVAGTHRLAAGDFSTRVAVSSQDELGRLALDFNQLATSLEKNEQMRRAVMA
DVSHELRTPLAVLRGELEALQDGVRQPTPASLSSLLAEVATLTKLVDDLHQLSLSDLGALAYRKSPLDCVHLLQVAVASF
RDRFHAKGLEIVTLLPEQAPLFGDPDRLNQLFNNLLENSLRYTDAEGKLEIGAESLPGRLLIYWQDSAPGVNDEQLALIF
ERFYRTEGSRNRASGGSGLGLSICQNIVEAHNGKIYAQHSPLGGVRITVEFATPVMNKAS

Specific function: Member of the two-component regulatory system BaeS/BaeR. May activate BaeR by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1788393, Length=451, Percent_Identity=67.4057649667406, Blast_Score=608, Evalue=1e-175,
Organism=Escherichia coli, GI1790346, Length=266, Percent_Identity=30.4511278195489, Blast_Score=117, Evalue=2e-27,
Organism=Escherichia coli, GI1786783, Length=290, Percent_Identity=25.8620689655172, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI1786912, Length=278, Percent_Identity=29.8561151079137, Blast_Score=97, Evalue=3e-21,
Organism=Escherichia coli, GI87081816, Length=260, Percent_Identity=28.8461538461538, Blast_Score=96, Evalue=4e-21,
Organism=Escherichia coli, GI1787894, Length=301, Percent_Identity=26.578073089701, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1786600, Length=289, Percent_Identity=26.9896193771626, Blast_Score=90, Evalue=3e-19,
Organism=Escherichia coli, GI1787374, Length=295, Percent_Identity=26.1016949152542, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI145693157, Length=255, Percent_Identity=25.8823529411765, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1789149, Length=381, Percent_Identity=23.6220472440945, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1790861, Length=315, Percent_Identity=25.0793650793651, Blast_Score=80, Evalue=3e-16,
Organism=Escherichia coli, GI1789808, Length=295, Percent_Identity=28.8135593220339, Blast_Score=80, Evalue=4e-16,
Organism=Escherichia coli, GI87082128, Length=272, Percent_Identity=27.2058823529412, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788279, Length=312, Percent_Identity=25, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1788713, Length=245, Percent_Identity=26.1224489795918, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI1788549, Length=260, Percent_Identity=26.5384615384615, Blast_Score=74, Evalue=3e-14,
Organism=Escherichia coli, GI1790551, Length=282, Percent_Identity=26.9503546099291, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789403, Length=295, Percent_Identity=30.1694915254237, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1790436, Length=202, Percent_Identity=29.7029702970297, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 51510; Mature: 51510

Theoretical pI: Translated: 7.45; Mature: 7.45

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIGITGKLFMAIFATCMLVLITMHWGVRVSFERGFIDYIKNSNEQRINMLSEALEEQYS
CCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHH
HHGNWVFLRNNDQVVYQIMRSFEQNSDSSHNLPPKGWRTQFWVVDSQFNRLVGHSGPLPK
CCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCCCCCCC
EGPRHPIRYNNEIVGWVLTTPVERLTRNTDINFDQQQRRTSWMIVALSTLLAAAVTWLMS
CCCCCCCCCCCEEEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLLAPVKRLVAGTHRLAAGDFSTRVAVSSQDELGRLALDFNQLATSLEKNEQMRRAVMA
CCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVSHELRTPLAVLRGELEALQDGVRQPTPASLSSLLAEVATLTKLVDDLHQLSLSDLGAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYRKSPLDCVHLLQVAVASFRDRFHAKGLEIVTLLPEQAPLFGDPDRLNQLFNNLLENSL
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHC
RYTDAEGKLEIGAESLPGRLLIYWQDSAPGVNDEQLALIFERFYRTEGSRNRASGGSGLG
CCCCCCCCEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LSICQNIVEAHNGKIYAQHSPLGGVRITVEFATPVMNKAS
HHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure
MKIGITGKLFMAIFATCMLVLITMHWGVRVSFERGFIDYIKNSNEQRINMLSEALEEQYS
CCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHCCCHHHHHHHHHHHHHHHH
HHGNWVFLRNNDQVVYQIMRSFEQNSDSSHNLPPKGWRTQFWVVDSQFNRLVGHSGPLPK
CCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCHHHHHHCCCCCCCC
EGPRHPIRYNNEIVGWVLTTPVERLTRNTDINFDQQQRRTSWMIVALSTLLAAAVTWLMS
CCCCCCCCCCCEEEEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RGLLAPVKRLVAGTHRLAAGDFSTRVAVSSQDELGRLALDFNQLATSLEKNEQMRRAVMA
CCHHHHHHHHHHHHHHHCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVSHELRTPLAVLRGELEALQDGVRQPTPASLSSLLAEVATLTKLVDDLHQLSLSDLGAL
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AYRKSPLDCVHLLQVAVASFRDRFHAKGLEIVTLLPEQAPLFGDPDRLNQLFNNLLENSL
HHCCCCHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHC
RYTDAEGKLEIGAESLPGRLLIYWQDSAPGVNDEQLALIFERFYRTEGSRNRASGGSGLG
CCCCCCCCEEECCCCCCCEEEEEECCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCC
LSICQNIVEAHNGKIYAQHSPLGGVRITVEFATPVMNKAS
HHHHHHHHHHCCCEEEEECCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8282725; 9097040; 9278503 [H]