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The map label for this gene is mdtA [H]

Identifier: 157371787

GI number: 157371787

Start: 3924302

End: 3925543

Strand: Direct

Name: mdtA [H]

Synonym: Spro_3552

Alternate gene names: 157371787

Gene position: 3924302-3925543 (Clockwise)

Preceding gene: 157371785

Following gene: 157371788

Centisome position: 72.02

GC content: 58.86

Gene sequence:

>1242_bases
ATGAATGCAAAAAACCCACGTCGTTCACTGATACTGCGCCTGCTGGTGGTGGTCATTGTGGCTATTGCCGCCGTGCTGAT
TTGGCGTCACTTCCGCGCTGCGCAACCTGCCACGGATGCTGCACCGCATGCGCGCCACGCAGGTAAAGGCCAGGCGGCCG
CTGGCCGACGTGGGGCACCGATGTCACCGGTACAGGCCGCGACCGTCACGCAGCAGACGGTACCACGCTATCTTTCCGGA
CTGGGCACCGCCACCGCCGCCAACACCGTGACCGTCACCAGCCGGGTTGATGGCCAACTGATGGCTATCCACTTTACCGA
AGGCCAACAGGTCAAGGCAGGCGATCTGCTGGTGGAAATCGACCCGCGCCCGTTTGAAGTGCAACTGACTCAGGCGTTGG
GGCAACTGGCAAAAGACCAGGCCACGCTCGCTAATGCCCGGCGCGATTTGGCGCGTTACCAGCAACTGGCGAAAACCAAT
CTGGTTTCGCGGCAGGATCTGGATACCCAATTGTCATTAGTGCAGCAGACTGAGGGGGCGATCAAGGCCGATCAGGGCAC
GGTGGACAGCGCCAGACTGCAAATCACCTACAGTCGCATCACCGCGCCGATCGACGGTCGCGTCGGCCTGAAACTGGTGG
ATGTCGGCAATTACATCACCAGCGGCAGCACCACCGGCATTGTGGTGATCACCCAAACTCATCCTATCGACGTGGTGTTT
ACCCTGCCGGAAGCCAATATCAGCGACTTGATCAAAGCGCAAAAAACCGGCCCGGTTAGCGTCGAAGCCTGGGATCGCAC
CAACCAAAATCAACTGGCAACCGGTTCATTACTGAGCCTGGATAACCAAATCGACACCACCACCGGCACCATCAAACTCA
AGGCGCGTTTCACCAACGAGGACGATGCGCTGTTTCCCAACCAGTTTGTGAATGCACGTTTGAAGGTGGCGACGCTGCAC
GATGCCATGGTCATCCCGACCGCAGCGCTACAGATGGGCAACGAAGGCAACTTCGTCTGGACCCTGAGTGAAGAGAACAA
AGTCAACAAACACCTGGTTACCACCGGCATGCAGGATAGCCAACAGGTGGTGATCACCGCCGGCCTGAACGTCGGCGATC
GGGTGGTCACCGACGGTATCGATCGTCTGACTGAAGGCATGCAGGTAGAAGTGGTGACGCCGCAGGCGGCTTCGGCAGCG
ACTAAACCGAACCAACCAACTCGCGCTCAGGGGAAATCCTGA

Upstream 100 bases:

>100_bases
TTATGCCGTCTTGACTGGCTAAACTAGTATCCTGTAAGGAGTGTAACTTTTTTGGCAATGAGTGCCCGCACGCCTGCCTT
TTGGAGATATTTTCACCACC

Downstream 100 bases:

>100_bases
TGCAGGTGATGCCACCTAACCCCGGCGGTGGCCCATCCCGCCTGTTTATTCTGCGCCCGGTCGCGACCACGCTGTTGATG
GTGGCGATCCTGCTGGCGGG

Product: multidrug efflux system subunit MdtA

Products: NA

Alternate protein names: Multidrug transporter mdtA [H]

Number of amino acids: Translated: 413; Mature: 413

Protein sequence:

>413_residues
MNAKNPRRSLILRLLVVVIVAIAAVLIWRHFRAAQPATDAAPHARHAGKGQAAAGRRGAPMSPVQAATVTQQTVPRYLSG
LGTATAANTVTVTSRVDGQLMAIHFTEGQQVKAGDLLVEIDPRPFEVQLTQALGQLAKDQATLANARRDLARYQQLAKTN
LVSRQDLDTQLSLVQQTEGAIKADQGTVDSARLQITYSRITAPIDGRVGLKLVDVGNYITSGSTTGIVVITQTHPIDVVF
TLPEANISDLIKAQKTGPVSVEAWDRTNQNQLATGSLLSLDNQIDTTTGTIKLKARFTNEDDALFPNQFVNARLKVATLH
DAMVIPTAALQMGNEGNFVWTLSEENKVNKHLVTTGMQDSQQVVITAGLNVGDRVVTDGIDRLTEGMQVEVVTPQAASAA
TKPNQPTRAQGKS

Sequences:

>Translated_413_residues
MNAKNPRRSLILRLLVVVIVAIAAVLIWRHFRAAQPATDAAPHARHAGKGQAAAGRRGAPMSPVQAATVTQQTVPRYLSG
LGTATAANTVTVTSRVDGQLMAIHFTEGQQVKAGDLLVEIDPRPFEVQLTQALGQLAKDQATLANARRDLARYQQLAKTN
LVSRQDLDTQLSLVQQTEGAIKADQGTVDSARLQITYSRITAPIDGRVGLKLVDVGNYITSGSTTGIVVITQTHPIDVVF
TLPEANISDLIKAQKTGPVSVEAWDRTNQNQLATGSLLSLDNQIDTTTGTIKLKARFTNEDDALFPNQFVNARLKVATLH
DAMVIPTAALQMGNEGNFVWTLSEENKVNKHLVTTGMQDSQQVVITAGLNVGDRVVTDGIDRLTEGMQVEVVTPQAASAA
TKPNQPTRAQGKS
>Mature_413_residues
MNAKNPRRSLILRLLVVVIVAIAAVLIWRHFRAAQPATDAAPHARHAGKGQAAAGRRGAPMSPVQAATVTQQTVPRYLSG
LGTATAANTVTVTSRVDGQLMAIHFTEGQQVKAGDLLVEIDPRPFEVQLTQALGQLAKDQATLANARRDLARYQQLAKTN
LVSRQDLDTQLSLVQQTEGAIKADQGTVDSARLQITYSRITAPIDGRVGLKLVDVGNYITSGSTTGIVVITQTHPIDVVF
TLPEANISDLIKAQKTGPVSVEAWDRTNQNQLATGSLLSLDNQIDTTTGTIKLKARFTNEDDALFPNQFVNARLKVATLH
DAMVIPTAALQMGNEGNFVWTLSEENKVNKHLVTTGMQDSQQVVITAGLNVGDRVVTDGIDRLTEGMQVEVVTPQAASAA
TKPNQPTRAQGKS

Specific function: Unknown

COG id: COG0845

COG function: function code M; Membrane-fusion protein

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

Organism=Escherichia coli, GI87082036, Length=363, Percent_Identity=72.1763085399449, Blast_Score=525, Evalue=1e-150,
Organism=Escherichia coli, GI1789929, Length=323, Percent_Identity=30.3405572755418, Blast_Score=140, Evalue=1e-34,
Organism=Escherichia coli, GI1789665, Length=329, Percent_Identity=31.0030395136778, Blast_Score=139, Evalue=4e-34,
Organism=Escherichia coli, GI1786668, Length=337, Percent_Identity=30.2670623145401, Blast_Score=127, Evalue=1e-30,
Organism=Escherichia coli, GI87081951, Length=161, Percent_Identity=30.4347826086957, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI87081796, Length=340, Percent_Identity=25.8823529411765, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022824
- InterPro:   IPR006143 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 44280; Mature: 44280

Theoretical pI: Translated: 9.84; Mature: 9.84

Prosite motif: PS00037 MYB_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNAKNPRRSLILRLLVVVIVAIAAVLIWRHFRAAQPATDAAPHARHAGKGQAAAGRRGAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MSPVQAATVTQQTVPRYLSGLGTATAANTVTVTSRVDGQLMAIHFTEGQQVKAGDLLVEI
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEECCCCEEECCCEEEEE
DPRPFEVQLTQALGQLAKDQATLANARRDLARYQQLAKTNLVSRQDLDTQLSLVQQTEGA
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
IKADQGTVDSARLQITYSRITAPIDGRVGLKLVDVGNYITSGSTTGIVVITQTHPIDVVF
EECCCCCCCCEEEEEEEHHEECCCCCCCCEEEEEECCEEECCCCCEEEEEEECCCEEEEE
TLPEANISDLIKAQKTGPVSVEAWDRTNQNQLATGSLLSLDNQIDTTTGTIKLKARFTNE
ECCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCEEEEEEEEECCC
DDALFPNQFVNARLKVATLHDAMVIPTAALQMGNEGNFVWTLSEENKVNKHLVTTGMQDS
CCCCCCCHHHCCEEEEEEECCCCEECHHHHHCCCCCCEEEEECCCCCCCCEEEECCCCCC
QQVVITAGLNVGDRVVTDGIDRLTEGMQVEVVTPQAASAATKPNQPTRAQGKS
CEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MNAKNPRRSLILRLLVVVIVAIAAVLIWRHFRAAQPATDAAPHARHAGKGQAAAGRRGAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCC
MSPVQAATVTQQTVPRYLSGLGTATAANTVTVTSRVDGQLMAIHFTEGQQVKAGDLLVEI
CCCCHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEECCCEEEEEEECCCCEEECCCEEEEE
DPRPFEVQLTQALGQLAKDQATLANARRDLARYQQLAKTNLVSRQDLDTQLSLVQQTEGA
CCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCC
IKADQGTVDSARLQITYSRITAPIDGRVGLKLVDVGNYITSGSTTGIVVITQTHPIDVVF
EECCCCCCCCEEEEEEEHHEECCCCCCCCEEEEEECCEEECCCCCEEEEEEECCCEEEEE
TLPEANISDLIKAQKTGPVSVEAWDRTNQNQLATGSLLSLDNQIDTTTGTIKLKARFTNE
ECCCCCHHHHHHHCCCCCEEEEECCCCCCCCCCCCCEEECCCCCCCCCEEEEEEEEECCC
DDALFPNQFVNARLKVATLHDAMVIPTAALQMGNEGNFVWTLSEENKVNKHLVTTGMQDS
CCCCCCCHHHCCEEEEEEECCCCEECHHHHHCCCCCCEEEEECCCCCCCCEEEECCCCCC
QQVVITAGLNVGDRVVTDGIDRLTEGMQVEVVTPQAASAATKPNQPTRAQGKS
CEEEEEECCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA