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The map label for this gene is hicB2 [H]

Identifier: 157371637

GI number: 157371637

Start: 3759279

End: 3759719

Strand: Direct

Name: hicB2 [H]

Synonym: Spro_3400

Alternate gene names: 157371637

Gene position: 3759279-3759719 (Clockwise)

Preceding gene: 157371635

Following gene: 157371640

Centisome position: 68.99

GC content: 54.65

Gene sequence:

>441_bases
ATGTCTTGCCACTACCCCGCCCAATACACCTTTGATAACGACAGCGACGCCTGGCAGATTCAGTTTCGTGATTTTCCTCA
GCAACAGGCTGCCTGCTATAAGCGTGAAGACATCGAACTGGAAGCACAGGAAAGCCTGCTGATTGCCATAGCGCTGGAAA
TGGAAGAAGGCCGCCCGGTACCGGCCCCTTCTCGTGCCTTGCCGGATGAGCTGGCGATCCACCTGCCGGTGCTGGTTAAA
CTCAAGCTCGAGTTGCATAACATTATGCTGGCCGATACCACGTCCAAAGCCAGCCTGGCGCGTAAACTGGGCTTTAACGC
CGGCCAAATGGACCGCCTGTTGGATGTGGCCTATGCCTCCAAGGTAGAAGCGCTGGAACAGGCTCTTTATCTGTTGGGAT
ATGAGGTACAAACCTCGGTAGCAGAGATCCGCCAGCAATAA

Upstream 100 bases:

>100_bases
CCAATGAGAACAACTATCATCTCCACCCGGTACAACACTGGCTATCTGCGGGCCAAGCGGTCACAATGCCGCACCACTCC
CGGCCCAAACAGGAAATACC

Downstream 100 bases:

>100_bases
GAAAAATATTTTATTCGGGGGCTAAATTTTCTCCATTTTTCGCCGATGTGTTCATTACCGAATCATCAAGAGCAAAAAGT
GAAGGCTAAAAATGGAGTGG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 146; Mature: 145

Protein sequence:

>146_residues
MSCHYPAQYTFDNDSDAWQIQFRDFPQQQAACYKREDIELEAQESLLIAIALEMEEGRPVPAPSRALPDELAIHLPVLVK
LKLELHNIMLADTTSKASLARKLGFNAGQMDRLLDVAYASKVEALEQALYLLGYEVQTSVAEIRQQ

Sequences:

>Translated_146_residues
MSCHYPAQYTFDNDSDAWQIQFRDFPQQQAACYKREDIELEAQESLLIAIALEMEEGRPVPAPSRALPDELAIHLPVLVK
LKLELHNIMLADTTSKASLARKLGFNAGQMDRLLDVAYASKVEALEQALYLLGYEVQTSVAEIRQQ
>Mature_145_residues
SCHYPAQYTFDNDSDAWQIQFRDFPQQQAACYKREDIELEAQESLLIAIALEMEEGRPVPAPSRALPDELAIHLPVLVKL
KLELHNIMLADTTSKASLARKLGFNAGQMDRLLDVAYASKVEALEQALYLLGYEVQTSVAEIRQQ

Specific function: Part of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin preventing effects of the HicA 2 toxin [H]

COG id: COG1598

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH cro/C1-type DNA-binding domain [H]

Homologues:

None

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005357 [H]

Pfam domain/function: PF03681 UPF0150 [H]

EC number: NA

Molecular weight: Translated: 16480; Mature: 16349

Theoretical pI: Translated: 4.46; Mature: 4.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSCHYPAQYTFDNDSDAWQIQFRDFPQQQAACYKREDIELEAQESLLIAIALEMEEGRPV
CCCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHCCCCCEECCCCEEEEEEEEECCCCCC
PAPSRALPDELAIHLPVLVKLKLELHNIMLADTTSKASLARKLGFNAGQMDRLLDVAYAS
CCCCCCCCHHHHHHCCEEEEEEEEHHEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHH
KVEALEQALYLLGYEVQTSVAEIRQQ
HHHHHHHHHHHHCHHHHHHHHHHHCC
>Mature Secondary Structure 
SCHYPAQYTFDNDSDAWQIQFRDFPQQQAACYKREDIELEAQESLLIAIALEMEEGRPV
CCCCCCEEEECCCCCEEEEEECCCCHHHHHHHHCCCCCEECCCCEEEEEEEEECCCCCC
PAPSRALPDELAIHLPVLVKLKLELHNIMLADTTSKASLARKLGFNAGQMDRLLDVAYAS
CCCCCCCCHHHHHHCCEEEEEEEEHHEEEEECCCCHHHHHHHHCCCCCHHHHHHHHHHHH
KVEALEQALYLLGYEVQTSVAEIRQQ
HHHHHHHHHHHHCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 14528314 [H]