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The map label for this gene is flk [H]

Identifier: 157371589

GI number: 157371589

Start: 3708549

End: 3709577

Strand: Direct

Name: flk [H]

Synonym: Spro_3352

Alternate gene names: 157371589

Gene position: 3708549-3709577 (Clockwise)

Preceding gene: 157371584

Following gene: 157371596

Centisome position: 68.06

GC content: 59.18

Gene sequence:

>1029_bases
ATGCAACCTTTGAGTGGACCGGGCACCCCGATCGCCAGCGATCGTTCCCCTAGCCCGGACAAAACCACCACCACTGACGG
TAGCCCGCTCTCCCCGGCACAACGCACGACGCTGGAGAAGCTGGTCGTCAAGATCATGGCGCTCAGCCCGGCCAAGTCCG
CAGAGATCTGGGTCACGCTGCGTCATGACCTGCAAACGGACAACAACAGTGAGCTACTGGCACGCCATTTCCAACCGGCC
GAGCAACTGTTGCAAAACCGCCTGGCACAGGTGCAGCAAAGCCATGCCAACCGCCAATTGTTGCAGCAACTCACCGATCT
GCTGCCGCAGGGCAATAACCGCCAGGCCGTCAGCGACTTTATTCGCCAGCAGTTTGGCCATACGGTGCTGAGTCAATTGA
GCCACCCGCAGTTGCAGCAGGTACTGAACCTGTTGCAGACCGGCAGCCTGACCATCCCGCTCCCGCAACAAACCACCACC
AGCGATCGTCCGCTGTTGCCTGCCGAACATCAGAGCCTGCAACTGCAGGTGACCAAGCTGAGCGCCGCCACCGGCGAATC
ACCGGTCAAAATTTGGCAGACGCTATTTGATCTCAGCGGGGTCAAAACCAACGATCCGCTGCCGGCTCGCCATTTCCAAC
TGCTGAATCAGTTTTTGCAGGTGAAGGTAGCGCTGAGTCCACAAACCGCACCGACGCTGAACAATCTGTTGGCCGCACTG
AAACATCCTGCGGATCCGCAGGAGCAGCAACAGTTGAATGACTACTGTCAGTCACGTTTTCACTGCAATGCCGGCGCACC
GCTGACCCATCCGCAGATGAGCGACCTGATCAACCAGCTGTTTGCGCGTCGTCTGGAAAAGACCGGCCCGGCACAGCCGC
TGTCCGGCAGCCACGCCGAACCGCAGCCGTTGCTCAACCCACTGATTGCCGCCCTGCCCCAACCGCTGCAAAAAGCGCTG
AGCAAACCGGCCGTGGCGTTTATCCTGTTTATTCTGGTGCTGGCTCTGGTATTGGCGCTGGTGTTTTAA

Upstream 100 bases:

>100_bases
TGAGGACGGTATTGGTCGCGGCCGTTTACAGGTATCATAAGAACAATCCTGCGCTTTTCGCCGGGTACGACGATTTTCTA
CACAGCGAAGGACAGGTGAT

Downstream 100 bases:

>100_bases
CTTTTTGACTTCCCGGCAACCTATTTCCTGGCCAGCGGATAACCCTTATCCAAGGCCAGACTGGGTATGGTGCTCGGAGG
CTTCAAGCTTGAATTGACGC

Product: flagella biosynthesis regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 342; Mature: 342

Protein sequence:

>342_residues
MQPLSGPGTPIASDRSPSPDKTTTTDGSPLSPAQRTTLEKLVVKIMALSPAKSAEIWVTLRHDLQTDNNSELLARHFQPA
EQLLQNRLAQVQQSHANRQLLQQLTDLLPQGNNRQAVSDFIRQQFGHTVLSQLSHPQLQQVLNLLQTGSLTIPLPQQTTT
SDRPLLPAEHQSLQLQVTKLSAATGESPVKIWQTLFDLSGVKTNDPLPARHFQLLNQFLQVKVALSPQTAPTLNNLLAAL
KHPADPQEQQQLNDYCQSRFHCNAGAPLTHPQMSDLINQLFARRLEKTGPAQPLSGSHAEPQPLLNPLIAALPQPLQKAL
SKPAVAFILFILVLALVLALVF

Sequences:

>Translated_342_residues
MQPLSGPGTPIASDRSPSPDKTTTTDGSPLSPAQRTTLEKLVVKIMALSPAKSAEIWVTLRHDLQTDNNSELLARHFQPA
EQLLQNRLAQVQQSHANRQLLQQLTDLLPQGNNRQAVSDFIRQQFGHTVLSQLSHPQLQQVLNLLQTGSLTIPLPQQTTT
SDRPLLPAEHQSLQLQVTKLSAATGESPVKIWQTLFDLSGVKTNDPLPARHFQLLNQFLQVKVALSPQTAPTLNNLLAAL
KHPADPQEQQQLNDYCQSRFHCNAGAPLTHPQMSDLINQLFARRLEKTGPAQPLSGSHAEPQPLLNPLIAALPQPLQKAL
SKPAVAFILFILVLALVLALVF
>Mature_342_residues
MQPLSGPGTPIASDRSPSPDKTTTTDGSPLSPAQRTTLEKLVVKIMALSPAKSAEIWVTLRHDLQTDNNSELLARHFQPA
EQLLQNRLAQVQQSHANRQLLQQLTDLLPQGNNRQAVSDFIRQQFGHTVLSQLSHPQLQQVLNLLQTGSLTIPLPQQTTT
SDRPLLPAEHQSLQLQVTKLSAATGESPVKIWQTLFDLSGVKTNDPLPARHFQLLNQFLQVKVALSPQTAPTLNNLLAAL
KHPADPQEQQQLNDYCQSRFHCNAGAPLTHPQMSDLINQLFARRLEKTGPAQPLSGSHAEPQPLLNPLIAALPQPLQKAL
SKPAVAFILFILVLALVLALVF

Specific function: Acts as a regulator of flagellar gene expression by modulating the protein level of the anti sigma factor flgM upon sensing ring completion or hook elongation. Flk could inhibit flgM secretion by acting as a braking system for the flagellar- associated ty

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the flk family [H]

Homologues:

Organism=Escherichia coli, GI1788661, Length=320, Percent_Identity=44.6875, Blast_Score=240, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

NA

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 37538; Mature: 37538

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQPLSGPGTPIASDRSPSPDKTTTTDGSPLSPAQRTTLEKLVVKIMALSPAKSAEIWVTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
RHDLQTDNNSELLARHFQPAEQLLQNRLAQVQQSHANRQLLQQLTDLLPQGNNRQAVSDF
ECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IRQQFGHTVLSQLSHPQLQQVLNLLQTGSLTIPLPQQTTTSDRPLLPAEHQSLQLQVTKL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEH
SAATGESPVKIWQTLFDLSGVKTNDPLPARHFQLLNQFLQVKVALSPQTAPTLNNLLAAL
HHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEHHCCCCCCHHHHHHHHHH
KHPADPQEQQQLNDYCQSRFHCNAGAPLTHPQMSDLINQLFARRLEKTGPAQPLSGSHAE
HCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PQPLLNPLIAALPQPLQKALSKPAVAFILFILVLALVLALVF
CHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHC
>Mature Secondary Structure
MQPLSGPGTPIASDRSPSPDKTTTTDGSPLSPAQRTTLEKLVVKIMALSPAKSAEIWVTL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEE
RHDLQTDNNSELLARHFQPAEQLLQNRLAQVQQSHANRQLLQQLTDLLPQGNNRQAVSDF
ECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
IRQQFGHTVLSQLSHPQLQQVLNLLQTGSLTIPLPQQTTTSDRPLLPAEHQSLQLQVTKL
HHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCCCCCCCCCCEEEEEEH
SAATGESPVKIWQTLFDLSGVKTNDPLPARHFQLLNQFLQVKVALSPQTAPTLNNLLAAL
HHCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHEEHHCCCCCCHHHHHHHHHH
KHPADPQEQQQLNDYCQSRFHCNAGAPLTHPQMSDLINQLFARRLEKTGPAQPLSGSHAE
HCCCCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
PQPLLNPLIAALPQPLQKALSKPAVAFILFILVLALVLALVF
CHHHHHHHHHHCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9079927; 11677609 [H]