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The map label for this gene is katA [H]

Identifier: 157371515

GI number: 157371515

Start: 3620533

End: 3621969

Strand: Direct

Name: katA [H]

Synonym: Spro_3278

Alternate gene names: 157371515

Gene position: 3620533-3621969 (Clockwise)

Preceding gene: 157371513

Following gene: 157371522

Centisome position: 66.45

GC content: 55.39

Gene sequence:

>1437_bases
ATGAGCAAGAAAGGACTGACCACCGCAGCCGGCGCCCCGGTTGTCGATAATAATAACGTGATCACCGCCGGCAAACGCGG
CCCGATGTTGTTACAGGACGTGTGGTTTCTGGAAAAACTGGCCCATTTCGACCGTGAAGTGATCCCCGAGCGCCGCATGC
ACGCCAAAGGTTCCGGCGCCTACGGCACTTTCACCGTCACCCACGACATTAGCCAGTACACCCGCGCAAAAATCTTCTCT
GAAATCGGCAAGCAAACTGACATGTTCATCCGCTTCTCCACCGTAGCCGGTGAGCGTGGGGCCGCCGACGCCGAGCGTGA
CATTCGTGGTTTCGCCATGAAGTTTTATACCGAGGAAGGCAATTGGGATCTGGTGGGTAACGACACGCCGGTATTCTATC
TGCGCGATCCGCTGAAATTCCCCGACCTTAACCACGTAGTCAAACGCGATCCGCGCACCAATCTGCGTAACCCAACCTAC
AAGTGGGACTTCTTCTCGCTGTCACCGGAAAGCCTGCATCAGTTGACCATCGACTTCAGTGACCGCGGTATTCCTAAATC
CTATCGCCATATGCATGGTTTCGGCAGCCATACCTTCAGTTTTATCAATGCCGACAATGAACGCTTCTGGGTGAAGTTCC
ACTTCCGTTGCGAACAGGGTATTGAAAACCTGATGGATGATGAAGCAGAAGCGATTATCGCCAAAGACCGTGAAAGCTCG
CAGCGCGATCTGTATGAGGCCATCGAACGAGGTGATTTCCCACGCTGGAAGCTGCAAATCCAGATCATGCCGGAACACGA
AGCCTCTCAGACGCCATACAACCCATTCGATCTGACCAAGGTATGGCCGCATGGCGACTATCCGCTGATCGACGTGGGTT
TCTTCGAGCTGCACCGCAACCCGGAAAACTACTTCTCAGAAGTGGAGCAGGTGGCGATGAACCCGGCCAACGTGGTACCC
GGAGTGAGTTTCTCGCCGGACAAGATGCTGCAGGGGCGTCTGTTCTCCTACGGGGATACGCACCGTTATCGTCTGGGCGT
AAATCACCATCAAATCCCGGTGAACAGCCCAAAATGCCCGTTCCACAACTATCATCGTGACGGTGCGATGCGCGTGGACG
GTAACAGCGGCAACGGAGCCACCTACGAGCCAAACAGTTTCGGCCTGTTCCAGGAGCAACCGGACTTCAGCGAACCGCCG
TTGAGCATTGAAGGTGCCGCTGACCACTGGAATCACCGTGAAGACGATGATTACTACAGCCAGCCGCGCGCGCTGTTCAA
CCTGCTGAGTGCCGAAGAACACCAACGCATGTTCACCCGCATCGCCGGAGAGCTGTCGCAGGTGCCGGAACAGATCCAGC
GTCGTCAGGTTGAATTGTTTACCAAAGTGCACCCGAATTACGGTGCCGGCGTAGCCAAGGCGTTAGGTCTGAAATAA

Upstream 100 bases:

>100_bases
ATTGACCCAAGTCAGGGTAACCACGCCCTGCCAGATTATGATGATGAACGCTTACGCCGCCAGAATCTTAACTCGATTGC
ACTACAATAAGGAGCAAGTG

Downstream 100 bases:

>100_bases
CCCGCGTTACCCTCAAGGCCGCCTTCAGGCGGCCATTTTTATTGAGCCGAGATCTGCTCCACCGCCCATTGCTGCAACTG
ACGGCGCGAGATCTTGATAC

Product: catalase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 478; Mature: 477

Protein sequence:

>478_residues
MSKKGLTTAAGAPVVDNNNVITAGKRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDISQYTRAKIFS
EIGKQTDMFIRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPTY
KWDFFSLSPESLHQLTIDFSDRGIPKSYRHMHGFGSHTFSFINADNERFWVKFHFRCEQGIENLMDDEAEAIIAKDRESS
QRDLYEAIERGDFPRWKLQIQIMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGFFELHRNPENYFSEVEQVAMNPANVVP
GVSFSPDKMLQGRLFSYGDTHRYRLGVNHHQIPVNSPKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPP
LSIEGAADHWNHREDDDYYSQPRALFNLLSAEEHQRMFTRIAGELSQVPEQIQRRQVELFTKVHPNYGAGVAKALGLK

Sequences:

>Translated_478_residues
MSKKGLTTAAGAPVVDNNNVITAGKRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDISQYTRAKIFS
EIGKQTDMFIRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPTY
KWDFFSLSPESLHQLTIDFSDRGIPKSYRHMHGFGSHTFSFINADNERFWVKFHFRCEQGIENLMDDEAEAIIAKDRESS
QRDLYEAIERGDFPRWKLQIQIMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGFFELHRNPENYFSEVEQVAMNPANVVP
GVSFSPDKMLQGRLFSYGDTHRYRLGVNHHQIPVNSPKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPP
LSIEGAADHWNHREDDDYYSQPRALFNLLSAEEHQRMFTRIAGELSQVPEQIQRRQVELFTKVHPNYGAGVAKALGLK
>Mature_477_residues
SKKGLTTAAGAPVVDNNNVITAGKRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGAYGTFTVTHDISQYTRAKIFSE
IGKQTDMFIRFSTVAGERGAADAERDIRGFAMKFYTEEGNWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPTYK
WDFFSLSPESLHQLTIDFSDRGIPKSYRHMHGFGSHTFSFINADNERFWVKFHFRCEQGIENLMDDEAEAIIAKDRESSQ
RDLYEAIERGDFPRWKLQIQIMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGFFELHRNPENYFSEVEQVAMNPANVVPG
VSFSPDKMLQGRLFSYGDTHRYRLGVNHHQIPVNSPKCPFHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPPL
SIEGAADHWNHREDDDYYSQPRALFNLLSAEEHQRMFTRIAGELSQVPEQIQRRQVELFTKVHPNYGAGVAKALGLK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=472, Percent_Identity=53.3898305084746, Blast_Score=521, Evalue=1e-148,
Organism=Escherichia coli, GI48994891, Length=491, Percent_Identity=42.3625254582485, Blast_Score=373, Evalue=1e-104,
Organism=Caenorhabditis elegans, GI71998444, Length=472, Percent_Identity=52.7542372881356, Blast_Score=511, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI25151141, Length=475, Percent_Identity=49.6842105263158, Blast_Score=488, Evalue=1e-138,
Organism=Caenorhabditis elegans, GI25147792, Length=475, Percent_Identity=49.6842105263158, Blast_Score=488, Evalue=1e-138,
Organism=Saccharomyces cerevisiae, GI6320462, Length=484, Percent_Identity=43.1818181818182, Blast_Score=389, Evalue=1e-109,
Organism=Saccharomyces cerevisiae, GI6321525, Length=507, Percent_Identity=35.3057199211045, Blast_Score=309, Evalue=6e-85,
Organism=Drosophila melanogaster, GI17981717, Length=481, Percent_Identity=50.1039501039501, Blast_Score=479, Evalue=1e-135,
Organism=Drosophila melanogaster, GI19920968, Length=479, Percent_Identity=46.5553235908142, Blast_Score=452, Evalue=1e-127,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 54926; Mature: 54795

Theoretical pI: Translated: 6.40; Mature: 6.40

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSKKGLTTAAGAPVVDNNNVITAGKRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGA
CCCCCCCCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
YGTFTVTHDISQYTRAKIFSEIGKQTDMFIRFSTVAGERGAADAERDIRGFAMKFYTEEG
EEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHEEEEEEECCC
NWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPTYKWDFFSLSPESLHQLTIDFS
CEEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCHHHHEEEEEEEC
DRGIPKSYRHMHGFGSHTFSFINADNERFWVKFHFRCEQGIENLMDDEAEAIIAKDRESS
CCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHHHHHHHHHCCHHHEEEECCCCCH
QRDLYEAIERGDFPRWKLQIQIMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGFFELHRN
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEEEEHEEECCC
PENYFSEVEQVAMNPANVVPGVSFSPDKMLQGRLFSYGDTHRYRLGVNHHQIPVNSPKCP
HHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHCHHHCCCCCEEEEECCCCCCCCCCCCCCC
FHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPPLSIEGAADHWNHREDDDYYS
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHCCCCCCCCHHHH
QPRALFNLLSAEEHQRMFTRIAGELSQVPEQIQRRQVELFTKVHPNYGAGVAKALGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCC
>Mature Secondary Structure 
SKKGLTTAAGAPVVDNNNVITAGKRGPMLLQDVWFLEKLAHFDREVIPERRMHAKGSGA
CCCCCCCCCCCCEECCCCEEECCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHCCCCCCC
YGTFTVTHDISQYTRAKIFSEIGKQTDMFIRFSTVAGERGAADAERDIRGFAMKFYTEEG
EEEEEEECCHHHHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCHHHHHHHEEEEEEECCC
NWDLVGNDTPVFYLRDPLKFPDLNHVVKRDPRTNLRNPTYKWDFFSLSPESLHQLTIDFS
CEEEECCCCCEEEEECCCCCCCCHHHHHCCCCCCCCCCCEEEEEEECCHHHHEEEEEEEC
DRGIPKSYRHMHGFGSHTFSFINADNERFWVKFHFRCEQGIENLMDDEAEAIIAKDRESS
CCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEEEEHHHHHHHHHCCHHHEEEECCCCCH
QRDLYEAIERGDFPRWKLQIQIMPEHEASQTPYNPFDLTKVWPHGDYPLIDVGFFELHRN
HHHHHHHHHHCCCCCEEEEEEEECCCCCCCCCCCCCCCEEECCCCCCCEEEEEHEEECCC
PENYFSEVEQVAMNPANVVPGVSFSPDKMLQGRLFSYGDTHRYRLGVNHHQIPVNSPKCP
HHHHHHHHHHHHCCCHHHCCCCCCCHHHHHHCHHHCCCCCEEEEECCCCCCCCCCCCCCC
FHNYHRDGAMRVDGNSGNGATYEPNSFGLFQEQPDFSEPPLSIEGAADHWNHREDDDYYS
CCCCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEECCCHHCCCCCCCCHHHH
QPRALFNLLSAEEHQRMFTRIAGELSQVPEQIQRRQVELFTKVHPNYGAGVAKALGLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7786407; 7791219; 8901874; 12486720 [H]