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The map label for this gene is rtn [H]

Identifier: 157371482

GI number: 157371482

Start: 3577758

End: 3579344

Strand: Direct

Name: rtn [H]

Synonym: Spro_3245

Alternate gene names: 157371482

Gene position: 3577758-3579344 (Clockwise)

Preceding gene: 157371481

Following gene: 157371483

Centisome position: 65.66

GC content: 54.13

Gene sequence:

>1587_bases
ATGGGCTTGAAAAGGGCTTTTGCACGCCACGTTTCACACAGACGACGCAGTTTGGTTAAAAGCAGTGTCGTGGCCCTGGT
ATTTTTTATCCTGTTTATGGGGATTACGCTTTCGCTGATTAACCACCAGCGCACGCAATATCAACGTGCGGTAGAACAAC
GTACGCAGAAATTCACCCTCGATACCTTTAATAACCTGACTCAAATCATGCAGCGGTTGATGCCGCTAACCGAACAACCC
TGTAGCAGCAGCCAACCGGAAATTACCTATCAGGCGGCTTTTCATGCCGGCGTGCGTACCTTTATGTTGGTGAAAAACGG
CTTTGCCTATTGCTCTTCCGCCACCGGCGACATGATGTTGGCGCTGAAAAATATTTATCCGGAGATTGATCAACGCCAGC
GGTTGGATCTCAAATTGCAGCAAGGTACGCCACTGGTGCCGGGAAAACCGGCGTTCGCGGTTTGGCTGCGTCAGGCAGGC
AAGGAAGATACCGGCATACTGGCGACGCTGGATATCGGCCTGATGCCCCAACAGATGTTTGGCACCAGCCCCGAACGTGC
GCCAGGCATTGCCATTATTCTGGGCGATCGCGCCCTGACCAGCTTTAGCCCGAACCTGATGCCGGTCAACCAGTTGCCGG
ACGAAAAGGCCGACCGCATTTCCATCGCCGGCACCCCGATGATTATTATGTTTTATAACCAAAAATTGACGCCCAACGAT
ATCCGCCTGACTCTGCTGGGTAGTCTGGTGCTGTCCTTAATGATCGGCGTGCTGTGCTACTACATGCTGTTACTGCGCCA
AAGCCCGGAGCGCGCCCTGATGCGCGGCATCAAACGCAACGAATTCTTTATCGAGTATCAACCGGTATTTCATACCAAAA
CCGGCACCATCGCTGGGTTGGAAGCGCTGATCCGCTGGCAGCACCCGATCGAAGGACGTATTCCGCCGGATCTGTTTATT
CCCTACGCCGAAAGCGAAGGGCTGATAGTGCCGCTGACGCGTCACCTGTTCCGCCTGATTGCCGAAGACGCCCCCAGGCT
GGCGACGGCGCTGCCGCAGGGCGCCAAGCTCGGTCTGAACATCTCCCCTTCTCATCTCAGTGCGCCCTCTTTCCATCAGG
ACGTGTACGAACTGCTGGCGCAATTGCCGGGCAATTACTTTACGTTGGTATTTGAAATTACCGAGCGCGGCATGGTGGAG
GAAGGCAACGCGCTGGCGGAGTTCGACTGGTTGCATAAACAAGGCATTGAAATTGCCATCGATGACTTCGGTACCGGCCA
CAGCGCACTGATCTATCTGCAACGCTTTAGCATGGACTATCTGAAAATCGACCGCGGTTTCGTCAACTCCATCGGCCGGG
ATACGGTCACCGCACCGGTACTGGACGCGGTCATTTCACTGGCCAAAAAACTCAAAATGCAAACCGTGGCGGAGGGCGTA
GAAACCGCAGAACAGGTGAGCTTCCTGCAGGAACAGGACGTTAATTTTATGCAGGGGTACTATTACAGCAAACCGTTGAG
CATCGACAATTTTGTCGCCTTCTGCAACGCCCATACGGTCATGGACCATCAGGCGCTAACGGACTGA

Upstream 100 bases:

>100_bases
ATAAACGATGAATAATGACTGAGACACCGTCATTGCGATATATTAGGCAGTCACTCTATAACAAAAACAAATTGATACGC
CGTGTTCAGGGGGCAGGTTT

Downstream 100 bases:

>100_bases
ATCTTTTAACTTCTTTACTCTGCGGCGCGGCAGTAAATGTTATGCTGACCCAGATTTAATCGACTTAACAGCAGGAGCTT
ACCGTCAAGATGTCCGTGCG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 528; Mature: 527

Protein sequence:

>528_residues
MGLKRAFARHVSHRRRSLVKSSVVALVFFILFMGITLSLINHQRTQYQRAVEQRTQKFTLDTFNNLTQIMQRLMPLTEQP
CSSSQPEITYQAAFHAGVRTFMLVKNGFAYCSSATGDMMLALKNIYPEIDQRQRLDLKLQQGTPLVPGKPAFAVWLRQAG
KEDTGILATLDIGLMPQQMFGTSPERAPGIAIILGDRALTSFSPNLMPVNQLPDEKADRISIAGTPMIIMFYNQKLTPND
IRLTLLGSLVLSLMIGVLCYYMLLLRQSPERALMRGIKRNEFFIEYQPVFHTKTGTIAGLEALIRWQHPIEGRIPPDLFI
PYAESEGLIVPLTRHLFRLIAEDAPRLATALPQGAKLGLNISPSHLSAPSFHQDVYELLAQLPGNYFTLVFEITERGMVE
EGNALAEFDWLHKQGIEIAIDDFGTGHSALIYLQRFSMDYLKIDRGFVNSIGRDTVTAPVLDAVISLAKKLKMQTVAEGV
ETAEQVSFLQEQDVNFMQGYYYSKPLSIDNFVAFCNAHTVMDHQALTD

Sequences:

>Translated_528_residues
MGLKRAFARHVSHRRRSLVKSSVVALVFFILFMGITLSLINHQRTQYQRAVEQRTQKFTLDTFNNLTQIMQRLMPLTEQP
CSSSQPEITYQAAFHAGVRTFMLVKNGFAYCSSATGDMMLALKNIYPEIDQRQRLDLKLQQGTPLVPGKPAFAVWLRQAG
KEDTGILATLDIGLMPQQMFGTSPERAPGIAIILGDRALTSFSPNLMPVNQLPDEKADRISIAGTPMIIMFYNQKLTPND
IRLTLLGSLVLSLMIGVLCYYMLLLRQSPERALMRGIKRNEFFIEYQPVFHTKTGTIAGLEALIRWQHPIEGRIPPDLFI
PYAESEGLIVPLTRHLFRLIAEDAPRLATALPQGAKLGLNISPSHLSAPSFHQDVYELLAQLPGNYFTLVFEITERGMVE
EGNALAEFDWLHKQGIEIAIDDFGTGHSALIYLQRFSMDYLKIDRGFVNSIGRDTVTAPVLDAVISLAKKLKMQTVAEGV
ETAEQVSFLQEQDVNFMQGYYYSKPLSIDNFVAFCNAHTVMDHQALTD
>Mature_527_residues
GLKRAFARHVSHRRRSLVKSSVVALVFFILFMGITLSLINHQRTQYQRAVEQRTQKFTLDTFNNLTQIMQRLMPLTEQPC
SSSQPEITYQAAFHAGVRTFMLVKNGFAYCSSATGDMMLALKNIYPEIDQRQRLDLKLQQGTPLVPGKPAFAVWLRQAGK
EDTGILATLDIGLMPQQMFGTSPERAPGIAIILGDRALTSFSPNLMPVNQLPDEKADRISIAGTPMIIMFYNQKLTPNDI
RLTLLGSLVLSLMIGVLCYYMLLLRQSPERALMRGIKRNEFFIEYQPVFHTKTGTIAGLEALIRWQHPIEGRIPPDLFIP
YAESEGLIVPLTRHLFRLIAEDAPRLATALPQGAKLGLNISPSHLSAPSFHQDVYELLAQLPGNYFTLVFEITERGMVEE
GNALAEFDWLHKQGIEIAIDDFGTGHSALIYLQRFSMDYLKIDRGFVNSIGRDTVTAPVLDAVISLAKKLKMQTVAEGVE
TAEQVSFLQEQDVNFMQGYYYSKPLSIDNFVAFCNAHTVMDHQALTD

Specific function: Involved in resistance to phages N4 and lambda [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1788502, Length=508, Percent_Identity=45.6692913385827, Blast_Score=483, Evalue=1e-137,
Organism=Escherichia coli, GI87081980, Length=523, Percent_Identity=29.4455066921606, Blast_Score=210, Evalue=2e-55,
Organism=Escherichia coli, GI87081845, Length=524, Percent_Identity=29.1984732824427, Blast_Score=209, Evalue=3e-55,
Organism=Escherichia coli, GI1786507, Length=247, Percent_Identity=40.080971659919, Blast_Score=187, Evalue=1e-48,
Organism=Escherichia coli, GI87081743, Length=307, Percent_Identity=31.9218241042345, Blast_Score=153, Evalue=3e-38,
Organism=Escherichia coli, GI1787541, Length=237, Percent_Identity=35.4430379746835, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI87081921, Length=239, Percent_Identity=33.8912133891213, Blast_Score=131, Evalue=8e-32,
Organism=Escherichia coli, GI1790496, Length=242, Percent_Identity=33.0578512396694, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI226510982, Length=253, Percent_Identity=31.2252964426877, Blast_Score=113, Evalue=3e-26,
Organism=Escherichia coli, GI1788849, Length=240, Percent_Identity=29.5833333333333, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1787055, Length=240, Percent_Identity=30.4166666666667, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI87082096, Length=197, Percent_Identity=29.9492385786802, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787410, Length=167, Percent_Identity=28.7425149700599, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 59334; Mature: 59203

Theoretical pI: Translated: 7.42; Mature: 7.42

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGLKRAFARHVSHRRRSLVKSSVVALVFFILFMGITLSLINHQRTQYQRAVEQRTQKFTL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTFNNLTQIMQRLMPLTEQPCSSSQPEITYQAAFHAGVRTFMLVKNGFAYCSSATGDMML
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHCCCCCHHHH
ALKNIYPEIDQRQRLDLKLQQGTPLVPGKPAFAVWLRQAGKEDTGILATLDIGLMPQQMF
HHHHHCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHH
GTSPERAPGIAIILGDRALTSFSPNLMPVNQLPDEKADRISIAGTPMIIMFYNQKLTPND
CCCCCCCCCEEEEECCCHHHCCCCCCEECCCCCCCCCCEEEECCCCEEEEEECCCCCCCH
IRLTLLGSLVLSLMIGVLCYYMLLLRQSPERALMRGIKRNEFFIEYQPVFHTKTGTIAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEECEEECCCCHHHHH
EALIRWQHPIEGRIPPDLFIPYAESEGLIVPLTRHLFRLIAEDAPRLATALPQGAKLGLN
HHHHHCCCCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHCCCHHHHHCCCCCEECCC
ISPSHLSAPSFHQDVYELLAQLPGNYFTLVFEITERGMVEEGNALAEFDWLHKQGIEIAI
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEE
DDFGTGHSALIYLQRFSMDYLKIDRGFVNSIGRDTVTAPVLDAVISLAKKLKMQTVAEGV
ECCCCCCHHEEHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ETAEQVSFLQEQDVNFMQGYYYSKPLSIDNFVAFCNAHTVMDHQALTD
HHHHHHHHHHHHCCHHHHCEEECCCCCHHHHHHHHHHHHHHCCHHCCC
>Mature Secondary Structure 
GLKRAFARHVSHRRRSLVKSSVVALVFFILFMGITLSLINHQRTQYQRAVEQRTQKFTL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DTFNNLTQIMQRLMPLTEQPCSSSQPEITYQAAFHAGVRTFMLVKNGFAYCSSATGDMML
HHHHHHHHHHHHHCCCCCCCCCCCCCCEEEHHHHHHHHHHHHHHHCCHHHHCCCCCHHHH
ALKNIYPEIDQRQRLDLKLQQGTPLVPGKPAFAVWLRQAGKEDTGILATLDIGLMPQQMF
HHHHHCCCCCCCCCCCEEECCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEECCCCCHHHH
GTSPERAPGIAIILGDRALTSFSPNLMPVNQLPDEKADRISIAGTPMIIMFYNQKLTPND
CCCCCCCCCEEEEECCCHHHCCCCCCEECCCCCCCCCCEEEECCCCEEEEEECCCCCCCH
IRLTLLGSLVLSLMIGVLCYYMLLLRQSPERALMRGIKRNEFFIEYQPVFHTKTGTIAGL
HHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCCEEEEEECEEECCCCHHHHH
EALIRWQHPIEGRIPPDLFIPYAESEGLIVPLTRHLFRLIAEDAPRLATALPQGAKLGLN
HHHHHCCCCCCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHHCCCHHHHHCCCCCEECCC
ISPSHLSAPSFHQDVYELLAQLPGNYFTLVFEITERGMVEEGNALAEFDWLHKQGIEIAI
CCCCCCCCCCHHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCCHHHHHHHHHCCCEEEE
DDFGTGHSALIYLQRFSMDYLKIDRGFVNSIGRDTVTAPVLDAVISLAKKLKMQTVAEGV
ECCCCCCHHEEHHHHHCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
ETAEQVSFLQEQDVNFMQGYYYSKPLSIDNFVAFCNAHTVMDHQALTD
HHHHHHHHHHHHCCHHHHCEEECCCCCHHHHHHHHHHHHHHCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503; 9079933 [H]