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The map label for this gene is ycjZ [C]

Identifier: 157371338

GI number: 157371338

Start: 3408709

End: 3409608

Strand: Direct

Name: ycjZ [C]

Synonym: Spro_3099

Alternate gene names: 157371338

Gene position: 3408709-3409608 (Clockwise)

Preceding gene: 157371335

Following gene: 157371339

Centisome position: 62.56

GC content: 58.11

Gene sequence:

>900_bases
ATGTTAAAAGAAAACTTTAACGATTTAATTTCGTTTCTGATGGTCGCCCGCGAACGTAGCTTCACCAAAGCGGCGGCGAA
ACTTGGCGTTTCCCAATCGGCCTTGAGTCATGCCATCAGGGGGCTGGAAGAACGGCTGGAACTGCGTTTATTGACCCGAA
CCACCCGCAGCGTGGCACCTACCGAAGCCGGTGAAAGGCTGCTCAACAGCATCGGGCCGCGCTTTGCCGAGATTGAAAGT
GAACTGGATGCCCTGAGTGAAATGCGGGCACGTCCGGCGGGCAACATCCGCATCACCGCCGGCGAACATGCCGTCGACTC
GGTGCTGTGGCCGGTGTTGAAGACATTTCTGGCGGACTACCCGGATATCAATGTCGAGATCACCTTGGATAACACCCTGA
CCGATATCGTCAGCGGCCGTTTTGATGCCGGAATTCGTCTGGGTGAACAGGTCGCCAAGGATATGGTTGCGGTGCGTATC
GCAGCGGATATGCGCCTGATCCCCATCGCCTCCCCCGCTTATTTTGAACAATACGGCACGCCAACCACCCCGCAGGAACT
GCAAAACCATCGCTGCATCAATATGCGCTTACCCACCATGGGCGGTCTCTACGCCTGGGAGTTCGAAAAGGACGGGCGCG
AAATTAAGGTACGGGTCGACGGCCAGCTAACCTTTAACAGTCTGCGCCAACGCATTGACGCGGCGAGGCTCGGCTTCGGC
ATCGCCTTTGTCCCGCAAGACAGCGTCACCGATGAGCTGGCCGACGGCCGTTTGGTCCAGGTGCTCGACGAGTGGTGCCC
ACGGTTCCCCGGCTATTACCTCTATTATCCCAGCCGCAGGCAGCACACCACCGCCTTTGCGCTGTTTGTCGAGGCACTGC
GCTACCCACGGCAAGCCTGA

Upstream 100 bases:

>100_bases
AAAATGCACAAGGAGCTATGAGCTGAATTCATTAATTGTCGGTGGTCATCGCAAACGGCTAGAATATCGTCATTAATTCT
GCCCATACGGCGAGGCCGTG

Downstream 100 bases:

>100_bases
AAATCTAATTTCCATTCATAAAGCCAACAAAAAATCGCCGAAACAGCACAAGGTATGCAACGAAAGAGTAACAATTAGAG
TAACCTAGCCGCGCTTCAGG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MLKENFNDLISFLMVARERSFTKAAAKLGVSQSALSHAIRGLEERLELRLLTRTTRSVAPTEAGERLLNSIGPRFAEIES
ELDALSEMRARPAGNIRITAGEHAVDSVLWPVLKTFLADYPDINVEITLDNTLTDIVSGRFDAGIRLGEQVAKDMVAVRI
AADMRLIPIASPAYFEQYGTPTTPQELQNHRCINMRLPTMGGLYAWEFEKDGREIKVRVDGQLTFNSLRQRIDAARLGFG
IAFVPQDSVTDELADGRLVQVLDEWCPRFPGYYLYYPSRRQHTTAFALFVEALRYPRQA

Sequences:

>Translated_299_residues
MLKENFNDLISFLMVARERSFTKAAAKLGVSQSALSHAIRGLEERLELRLLTRTTRSVAPTEAGERLLNSIGPRFAEIES
ELDALSEMRARPAGNIRITAGEHAVDSVLWPVLKTFLADYPDINVEITLDNTLTDIVSGRFDAGIRLGEQVAKDMVAVRI
AADMRLIPIASPAYFEQYGTPTTPQELQNHRCINMRLPTMGGLYAWEFEKDGREIKVRVDGQLTFNSLRQRIDAARLGFG
IAFVPQDSVTDELADGRLVQVLDEWCPRFPGYYLYYPSRRQHTTAFALFVEALRYPRQA
>Mature_299_residues
MLKENFNDLISFLMVARERSFTKAAAKLGVSQSALSHAIRGLEERLELRLLTRTTRSVAPTEAGERLLNSIGPRFAEIES
ELDALSEMRARPAGNIRITAGEHAVDSVLWPVLKTFLADYPDINVEITLDNTLTDIVSGRFDAGIRLGEQVAKDMVAVRI
AADMRLIPIASPAYFEQYGTPTTPQELQNHRCINMRLPTMGGLYAWEFEKDGREIKVRVDGQLTFNSLRQRIDAARLGFG
IAFVPQDSVTDELADGRLVQVLDEWCPRFPGYYLYYPSRRQHTTAFALFVEALRYPRQA

Specific function: May have a role in the regulation of oprD expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787589, Length=295, Percent_Identity=48.8135593220339, Blast_Score=310, Evalue=6e-86,
Organism=Escherichia coli, GI1787128, Length=293, Percent_Identity=38.5665529010239, Blast_Score=225, Evalue=2e-60,
Organism=Escherichia coli, GI1786401, Length=295, Percent_Identity=30.8474576271186, Blast_Score=120, Evalue=1e-28,
Organism=Escherichia coli, GI87081978, Length=291, Percent_Identity=30.9278350515464, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1789440, Length=260, Percent_Identity=29.2307692307692, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI145693193, Length=286, Percent_Identity=30.7692307692308, Blast_Score=110, Evalue=1e-25,
Organism=Escherichia coli, GI1789639, Length=277, Percent_Identity=27.7978339350181, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=26.9360269360269, Blast_Score=90, Evalue=1e-19,
Organism=Escherichia coli, GI1789173, Length=263, Percent_Identity=27.3764258555133, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1788748, Length=120, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1790011, Length=278, Percent_Identity=23.021582733813, Blast_Score=69, Evalue=5e-13,
Organism=Escherichia coli, GI1788706, Length=261, Percent_Identity=23.3716475095785, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI145693105, Length=150, Percent_Identity=29.3333333333333, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI87082132, Length=261, Percent_Identity=22.6053639846743, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1787879, Length=139, Percent_Identity=32.3741007194245, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI157672245, Length=127, Percent_Identity=33.8582677165354, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 33695; Mature: 33695

Theoretical pI: Translated: 6.17; Mature: 6.17

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKENFNDLISFLMVARERSFTKAAAKLGVSQSALSHAIRGLEERLELRLLTRTTRSVAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TEAGERLLNSIGPRFAEIESELDALSEMRARPAGNIRITAGEHAVDSVLWPVLKTFLADY
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCC
PDINVEITLDNTLTDIVSGRFDAGIRLGEQVAKDMVAVRIAADMRLIPIASPAYFEQYGT
CCCEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCC
PTTPQELQNHRCINMRLPTMGGLYAWEFEKDGREIKVRVDGQLTFNSLRQRIDAARLGFG
CCCHHHHHCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCEECHHHHHHHHHHHHHCCC
IAFVPQDSVTDELADGRLVQVLDEWCPRFPGYYLYYPSRRQHTTAFALFVEALRYPRQA
EEECCCCCHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MLKENFNDLISFLMVARERSFTKAAAKLGVSQSALSHAIRGLEERLELRLLTRTTRSVAP
CCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
TEAGERLLNSIGPRFAEIESELDALSEMRARPAGNIRITAGEHAVDSVLWPVLKTFLADY
CHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCCEEEECCCHHHHHHHHHHHHHHHCCC
PDINVEITLDNTLTDIVSGRFDAGIRLGEQVAKDMVAVRIAADMRLIPIASPAYFEQYGT
CCCEEEEEECCHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCEEEEEECCHHHHHHCCC
PTTPQELQNHRCINMRLPTMGGLYAWEFEKDGREIKVRVDGQLTFNSLRQRIDAARLGFG
CCCHHHHHCCCEEEEECCCCCCEEEEEECCCCCEEEEEECCEECHHHHHHHHHHHHHCCC
IAFVPQDSVTDELADGRLVQVLDEWCPRFPGYYLYYPSRRQHTTAFALFVEALRYPRQA
EEECCCCCHHHHHHCCHHHHHHHHHCCCCCCEEEECCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043; 1427017 [H]